This document discusses anesthesia considerations for bronchoscopy procedures to remove foreign body inhalation. It notes that foreign body inhalation is most common in children ages 6 months to 3 years and presents highest risk in that age group due to exploring objects orally and lack of coordination. Rigid bronchoscopy is the standard approach for removal, requiring careful anesthesia to control breathing while the scope is inserted and foreign body extracted. Key goals are maintaining oxygenation and minimizing risks like pulmonary aspiration or dislodging the object during ventilation changes.
A basic overview on the management of intra-operative bronchospasm: the risk factors, triggers, diagnosis, prevention and management. Includes a case scenario – discussion.
A basic overview on the management of intra-operative bronchospasm: the risk factors, triggers, diagnosis, prevention and management. Includes a case scenario – discussion.
Children and even mentally retarded adults have the tendency to have habit of putting Foreign Bodies in their Nose themselves or by others. However treating surgeons are likely to forget nasal packs and splints as well.
Approach to non-infectious Upper Airway Obstruction “Stridor” in children.pptxJwan AlSofi
This lecture will discus the approach to stridor / upper airway obstruction in children and paediatric age group.
Topics to be discussed:-
Upper Airway Obstruction (UAO):- eitiology, clinical features, invetigations, treatment
Foreign Body Aspiration
Choanal Stenosis (Atresia)
Laryngomalacia (Floppy Larynx)
Subglottic Stenosis
Adenoidal and Tonsillar Hypertrophy
Others causes of UAO
This is a seminar presentation conducted by 4th year medical students under supervision of a lecturer. Reference were not attached here, but all information are from google, few textbooks and also from previous ENT posting's seminar.
to differentiate b/w wheezing and stridor....lead to know to make clinical dx for asthma, croup, laryngomalacia, epiglottis...there many noisy breathing....our focus wheezing n stridor....
This introductory lecture in thoracic surgery covers the following topics:
Development of the lung.
Developmental Anomalies.
Anatomy of the lungs and the bronchial tree.
Diagnostic procedures in thoracic surgery.
Closed tube thoracostomy.
Aspirated tracheobronchial foreign bodies.
Pulmonary hydatid cysts.
COMPLETE EXAMINATION OF RESPIRATORY SYSTEM IN PEDIATRICS. IT HAS BEEN SUMMARIZED FROM ALL WELL KNOWN 32 BOOKS UNDER GUIDANCE OF ONE OF THE BEST PEDIATRIC DOCTORS AND PROFESSORS .
BY DR. SURAJ R. DHANKIKAR.
COMPLETE EXAMINATION OF RESPIRATORY SYSTEM IN PEDIATRICS. IT HAS BEEN SUMMARIZED FROM ALL WELL KNOWN 32 BOOKS UNDER GUIDANCE OF ONE OF THE BEST PEDIATRIC DOCTORS AND PROFESSORS .
BY DR. SURAJ R. DHANKIKAR.
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...
management of foreign body inhalation and bronchoscopy in children
1. ANESTHESIA FOR FOREIGN BODY
INHALATION BRONCHOSCOPY
• By Dr. Vineet Chowdhary
• Moderator- Dr. Neelam Dogra
2. EPIDEMIOLOGY
• More than 17,000 ED visits for children
younger than 14 years (2000)
• 5th most common cause of unintentional-injury
mortality in the U.S.
• Leading cause of unintentional-injury
mortality in children less than 1 year
3. INCIDENCE
The maximum incidence of inhalation of foreign bodies occurs
in
AGE: 6 months to 3 years:
SEX:
Male >female
4. HISTORY
• During the 19th century, treatment of foreign body aspiration
by purges, bleeding, and emetics were largely ineffective.
• Mortality was estimated at 23%.
• This rate plummeted with the development of bronchoscopic
techniques for the removal of these foreign bodies.
• In 1897, Gustav Killian, a German otolaryngologist, performed
the first bronchoscopy using a rigid esophagoscope to
successfully remove a pig bone from a farmer’s right main
bronchus.
5. • Shortly thereafter, Chevalier Jackson developed the lighted
bronchoscope and several specialized instruments for the removal
of foreign bodies.
• While early clinicians used topical anesthesia, general anesthesia
became commonplace for the removal of aspirated objects with
increased experience with the rigid bronchoscope and advances in
anesthetic delivery.
• The flexible bronchoscope was introduced by Shigeto Ikeda in 1966,
and the removal of an airway foreign body using this instrument
was reported in the 1970s
6. WHO IS AT RISK?
In children: because
Natural urge to explore the objects by mouth
Tendency to put everything possible into their mouth
Lack of molar teeth to crush nuts
Crying and playing while eating
Lack of parental supervision
Immature glottis reflex
Incomplete coordination of mouth and tongue
7. WHO IS AT RISK? In elderly : because
Impaired cough reflex and swallow reflex
Mental retardation
Alcohol
General anesthesia
Poor dentition
Dental, pharyngeal and airway procedure
Loss of consciousness
Convulsions
Stroke
Parkinsonism
Maxillofacial trauma
Senile dementia
8. WHERE DOES IT GO?
The larynx
Trachea
Bronchus
Smaller airways
80-90 % occurs in bronchus ,mainly right main bronchus and lower
lobe
However Aspiration can occur in all lobes, including upper lobes
(though with less frequency)
9. REMEMBER!!
• Objects can fragment and lodge in multiple sites
(e.g., sunflower seeds)
• Children can aspirate several different objects
concurrently (or sequentially)
• Foreign bodies can erode through the esophagus
and cause respiratory symptoms
10. DANGEROUS
OBJECTS
• Round
• Balls, marbles
• More likely to cause complete
obstruction
• Break apart easily
• Compressibility
• Smooth, slippery surface
11. WHY RIGHT SIDE BRONCHUS IS MORE
COMMON?
• Larger Diameter
• Angle of divergence from the tracheal axis is smaller (More in
line with the trachea)
Airflow through the right bronchus
is greater
Situation of carina to left of the
midline of trachea.
12. WHAT GETS ASPIRATED?
According to source
Endogenous - vomitus or broken tooth
Exogenous - Pins, Peanut, seeds etc
According to nature of foreign body
Non-irritating type: plastic, metallic
Irritating(organic origin) : peanuts, beans, seeds etc.
14. PATHOPHYSIOLOGY
Organic foreign bodies (peanuts , Beans and seeds) absorb water
with time
Swelling rapidly change partial to complete bronchial obstruction
Long standing foreign body tends to move downward and
outward.
Mucosa becomes edematous partly closing over the foreign body
and even completely obliterating the lumen.
Foreign body becomes friable and fragments may dislodge into
other bronchus or smaller airways.
Foreign body produces inflammatory response and complications
like granulations and strictures
Removal of foreign body should be done as soon as possible.
However it does not justify hasty, ill planned and poorly equipped
bronchoscopy
15. HISTORY
In Children:
A history of a witnessed choking event is highly suggestive of
an acute aspiration.
In Adults:
H/O choking after eating or holding a foreign body in mouth
16. CLINICAL PRESENTATION
Depends upon the
Location of foreign body
Size of foreign body
Nature of foreign body
Time since inhalation
• HOWEVER, only 50% of diagnoses occur in the first 24
hours
• 80% within first week
• Will sometimes take years
17. CLINICAL PRESENTATION
In general, aspiration of foreign bodies produces the
following 3 phases:
Initial phase - Choking , gasping, coughing, or airway
obstruction at the time of aspiration
Asymptomatic phase - Subsequent lodging of the object with
relaxation of reflexes that often results in a reduction or
cessation of symptoms, lasting hours to weeks
Complication phase - Foreign body producing erosion or
obstruction leading to pneumonia, atelectasis , or abscess
Chronic long standing foreign body often present with
misdiagnosis of URI, asthma ,or pneumonia
18. OFTEN NEED HIGH
LEVEL OF SUSPICION TO
DIAGNOSE
TRACHEOBRONCHIAL FOREIGN BODY
19. • Classic triad in only 57%
• Wheeze, cough and decreased breath sounds
• 25-40% with normal exam
20. LARYNGEAL FOREIGN BODY
Present as sudden total or near total obstruction.
Initially cough then Hoarseness , Aphonia , Choking and
Dyspnoea .
And if total obstruction may cause asphyxia , cyanosis , and
death.
21. TRACHEAL FOREIGN BODY
Tracheal foreign bodies present similarly to laryngeal foreign
bodies but without hoarseness or aphonia.
Hemoptysis by sharp foreign body
Audible slap--heard at open mouth of child.
Palpatory thud.-on palpation of trachea
Asthmatoid wheeze--wheeze similar to asthma
22. BRONCHIAL FOREIGN BODY
In case of bronchial foreign body the classical clinical triad
consist of :
Paroxysmal Cough
Unilateral wheezing
Unilateral diminished breath sounds
23. VALVE MECHANISM
Three Mechanisms in bronchial obstruction:
Bypass mechanism(Two way valve)
Check valve mechanism (One way valve )
Stop valve mechanism(No way valve)
24. BYPASS VALVE (2 WAY)MECHANISM
• Partial obstruction
• Ingress and egress both occurs
• No collapse,no emphysema
TRACHEOBRONCHIAL
25. CHECK VALVE (1 WAY) MECHANISM
• On inspiration enlargement of diameter of bronchus opens a
small passage for ingress of air.
• On expiration Foreign body is embedded in swollen mucosa
preventing exit of air .
• Air is trapped inside and lung
becomes emphysematous.
(obstructive emphysema)
26. STOP VALVE (NO WAY) MECHANISM
• Both Ingress and egress stopped.
• Absorbtion of air results in collapse of lung.
(Obstructive atelectasis.)
28. INVESTIGATIONS
1. Chest X ray ( imaging modality of choice )
2. Fluoroscopy & video fluoroscopy
3. Chest CT
4. Virtual Bronchoscopy
29. CHEST XRAY
Chest radiograph to assess for other potential causes of symptoms,
to identify a radio opaque foreign body, or to detect the position of
a foreign body on the basis of localized emphysema and air-trapping,
atelectasis, infiltrate, or mediastinal shift
Radiopaque materials like metallic Foreign bodies are easily
identified on chest X rays
May show less dense objects like teeth, bone, shell, button.
Organic materials are not radiopaque but shows radiographic
abnormalities like
Hyperinflation due to Air trapping and shifting of the
mediastinum towards the opposite side.
Atelectasis
A final CXR for checking the presence and position of Foreign body
should be made immediately before bronchoscopy because
Foreign bodies often shifts.
36. • Many chest x-ray may have completely negative
findings ,especially within the first 24 hours following
aspiration.
• A positive history plus clinical symptoms of aspiration may
be sufficient to justify bronchoscopy.
37. CONSIDER LATERAL
DECUBITUS IF CHILD CANNOT
COOPERATE
• Lateral decubitus views [lower lung doesn’t collapse if FB present.]
38. COMPLICATIONS OF FOREIGN BODY
Obstructive emphysema
Atelectasis
Bronchiectasis
Pneumonia
Hemoptysis
Lung abscess
Subcutaneous Emphysema
Pneumothorax / pneumomediastinum
Granulation tissue and hemorrhage
Cartilage destruction
39. Emergency Treatment for Aspirated
Foreign Bodies
Note : none of
these should be
applied if patient
is able to speak
or cough
1.Heimlich maneuver
2.Back blows
3.Chest thrusts
4.Finger sweep / grasp
–(finger sweep should be done only if object is
visible and will not be pushed deeper)
40. HEIMLICH’S MANAEUVER
In erect (sitting/standing) position ,encircle from behind and fist
in epigastrium between the xiphoid and umblicus and apply
abdomen thrust
42. CHEST THRUST (STERNAL THRUST)
• For pregnant and massively
obese persons.
• Chest is encircled from
behind and fist is placed on
the midsternum.
TRACHEOBRONCHIAL
43. INFANT BACK BLOWS
• Rescuer sandwiches infant between
one hand supporting neck and the
other hand delivering back blows .
44. INFANT CHEST THRUST
• Rescuer holds infant on thigh in
head down position and delivers
upto 4 chest thrusts just like
chest compressions.
45. MANAGEMENT
If patient is in distress ->EMERGENCY BRONCHOSCOPY
If patient is stable ->PLANNED BRONCHOSCOPY
LARYNGEAL FOREIGN BODY:-> By direct laryngoscopy/Bronchoscopy
TRACHEAL OR BRONCHIAL FOREIGN BODY:-> Rigid bronchoscopy or
fibreoptic bronchoscope
Chest physical therapy
Bronchodialators
TRACHEOSTOMY indicated in
Laryngeal foreign body if Too large and sharp
46. MEASURES BEFORE
BRONCHOSCOPY
A Team Effort
Good communication and cooperation between
surgeon and anaesthetist
Senior ENT surgeon & expert Anaesthetist.
Light and suction checked before procedure.
Good venturi system
Proper size bronchoscope
Tracheostomy trolley should be ready
47. CHALLENGES
• Fighting irritable child.
• Full stomach.
• Sharing of airway.
• Difficult to maintain oxygenation and ventilation, as
pulmonary gas exchange is already reduced.
• Difficulty pertaining to pediatric airway
48. GOALS OF ANAESTHESIA
1. Adequate oxygenation.
2. A good i.v. access
3. Controlled cardiorespiratory reflexes during
bronchoscopy.
4. Rapid return of airway reflexes.
5. Prevention of pulmonary aspiration.
6. Meticulous monitoring : spo2,ECG,NIBP,EtCO2
49. RIGID BRONCHOSCOPE
Standard of care in most centers for evaluation
Allows visualization, ventilation, removal with multiple forceps and
ready management of mucosal hemorrhage
Successful in about 95% of cases
Complications are rare (about 1%)
Laryngeal and subglottic edema, atelectasis
Dislodgement of foreign body into more dangerous position
Hypoxic insults
Port for
venturi
Port for circuit
50.
51. PREOPERATIVE CONSIDERATIONS
The preoperative assessment should determine
• where the aspirated foreign body has lodged
• what was aspirated,
•when the aspiration occurred.
• time of the last meal .
PREMEDICATION
•Sedatives are avoided as it may precipitate total airway obstruction.
•Dexamethasone given prophylactically minimize postoperative stridor
and laryngeal edema.
•Anticholinergics (atropine, pyrolate) given to reduce secretions and
reflex bradycardia associated with airway instrumentation.
52. • If patient is not fasting then inj. ondansetron and inj.
Metaclopramide can be given.
• In urgent cases, induction by rapid sequence and cricoid
pressure. The stomach can be suctioned through a
nasogastric tube before the bronchoscope is inserted to
minimize the risk of gastric aspiration.
• In delayed presentations in which bronchoscopy is not
urgent, a preanesthetic fasting is appropriate.
53. Mask ventilation is done to maintain oxygen saturation before
inserting bronchoscope.
Once the scope introduced beyond the glottis, ventilation by
Jet ventilator with oxygen.
During active ventilation the distal end of the bronchoscope is
pulled back to the mid of the trachea and the proximal open
end is occluded with the thumb or a glass obturator.
Nitrous oxide is avoided, as it increases gas volume, air
trapping and possible rupture of affected lung.
Intermittent succinyl choline is administered till the procedure
is completed.
Later mask ventilation is done till the patient become fully
awake.
54. • After the extraction of the foreign body and the removal
of the rigid bronchoscope, the choice of ventilation during
emergence is influenced by pulmonary gas exchange and
the degree of airway edema.
• For uncomplicated cases,spontaneous ventilation assisted
by mask ventilation as needed may be adequate.
• Intubation during emergence may be indicated for a
marginal airway, pulmonary compromise,or residual
neuromuscular blockade.
56. ANAESTHETIC CONSIDERATIONS FOR
RIGID
BRONCHOSCOPY
• The conversion from spontaneous negative pressure breathing
to positive pressure ventilation theoretically risks dislodging an
unstable proximal body, causing complete obstruction.
• A survey of 838 paediatric anaesthesiologists found that the
majority preferred an inhaled induction when foreign bodies
were present in the tracheobronchial tree.
• A cautious IV induction that maintains spontaneous ventilation
is also possible
57. Controlled ventilation :
I.V. induction + muscle relaxant
and ventilation by
• 1) Venturi attachment
• 2) Inflation via side arm of bronchoscope
• 3) Insufflation via a catheter in the trachea
• 4) Insertion of a tube into the end of the bronchoscope
intermittently.
TRACHEOBRONCHIAL FOREIGN BODY
58. ANESTHETIC MAINTENANCE
• Oxygen, halo/iso.[ give more time for airway
manipulation] Or repeat ketamine/ propofol
• Suxa 0.25-0.5mg/kg with atropine 0.02mg/kg.
• Ventilation has to be intrupted while suctioning and
removal of foreign body.
• If foreign body is big/swollen tracheostomy may be
needed
59. • Big FB can be taken out in pieces.
• Apnea/ oxygen insufflation, is preferred at some crucial
time, ideally should not last beyond 1 min. After 5 min
hypercarbia may lead to dysrhythmias.
• If ventilation is inadequate with rigid bronchoscope, high
frequency jet ventilation via bronchoscope or ECMO can
be used.
• For FB embedded in mucosa, wait for 48-72hrs. Let odema
subside. Repeat bronchoscopy , if unsuccessful-thoracotomy.
60. • Spontaneous Ventilation
a) IV induction : with thiopentone, propofol, ketamine,
remifentanil.
Maintanance with halothane or propofol infusion
b) Inhalational induction with sevoflurane/halothane
Maintainance with halothane/isoflurane.
TRACHEOBRONCHIAL FOREIGN BODY
61. • An advantage of an IV anaesthetic is that it provides a
constant level of anesthesia irrespective of ventilation.
• Propofol is especially useful because of its rapid recovery
and also good reflex suppression.
• By contrast, hypoventilation and leaks around the rigid
bronchoscope may produce an inadequate depth of
inhaled anesthesia.
• Pollution of the operating room, due to the combination
of leaks around the rigid bronchoscope and high gas flows
needed for ventilation, are additional drawbacks of
inhalation anesthetics
62. • Laryngeal foreign bodiesremoved by direct
laryngoscopy.
• Tracheal and bronchial foreign bodies are best removed
using a rigid bronchoscope.
• Rigid bronchoscopy supersedes any form of conservative
approach like using bronchodilators, thoracic percussion
and postural drainage.
• However ,Preoperative physiotherapy, and antibiotics is
useful in a peripherally situated, organic, foreign body of
long standing, in which there is atelectasis of the lung with
pneumonia or abscess.
63. • In the rare event of being unable to remove a foreign body
endoscopically, it must be removed by thoracotomy or
bronchotomy.
• It is very important after removal of the foreign body, while
the child is still anaesthetized, that a second look is taken to
remove any remaining small fragments particularly in the case
of peanuts.
• Pus and mucus can be aspirated from the distal bronchus -
which helps in speeding the resolution of atelectasis or
pneumonia.
64. Intermittent succinyl choline
• Keeps the patient totally quiet during the procedure;
• Bronchial caliber does not vary
• Permits easy introduction of endoscope
TRACHEOBRONCHIAL FOREIGN BODY
65. DISADVANTAGE OF SPONTANEOUS
VENTILATION
• Some times foreign bodies may be too large to be withdrawn
through the lumen and it is common to loose the foreign body
during the removal, which commonly occur at subglottic region, if
the muscle relaxation is not adequate. This is known to occur often
with spontaneous ventilation technique and maintenance by
halothane.
• With Halothane as primary anaesthetic agent is that it requires
higher concentrations of halothane to obliterate airway reflexes
which may cause decreased myocardial contractility.
• Increased CO2
• Hard to GUARANTEE no movement: therefore additional airway
trauma may occur.
• Prolonged emergence
66. ADVANTAGES OF SPONTANEOUS
VENTILATION
• More effective alveolar ventilation- with difficulty in positive
pressure ventilation ,anesthesiologists typically exert more
pressure. For the patient with airway compromise, this results in
more turbulence in the upper airways and less effective air
exchange downstream.
• Better ventilation/perfusion matching
• Better ventilation during bronchoscopy with window closed
• Better ventilation during bronchoscopy with window open
• Foreign body mimic: not every patient believed to have a foreign
body, even if stridor is present, actually has one. If there is any
doubt, then spontaneous ventilation should be preserved in order
to make a diagnosis
67. • Neuromuscular blockade may worsen the situation by
converting a patient with a compromised airway to a
patient with no airway
• Multiple placements of forceps in difficult to grasp FB
cause gases to be exhausted to the room rather than
delivered to the patient during controlled ventilation,
unless the window is constantly replaced.
68. CONTROLLED VENTILATION
• Positive pressure ventilation down the bronchoscope,
with intermittent apnea while manipulating the
object,may be more suitable for distal foreign body
removal.
• The use of optical forceps allows for positive pressure
ventilation to be maintained while the foreign body is
being manipulated so that periods of apnea can be
minimized
TRACHEOBRONCHIAL FOREIGN BODY
69. ADVANTAGES OF CONTROLLED
VENTILATION
• A RSI allows more rapid control of the airway, lessening the
chance of aspiration
• Positive pressure ventilation avoids hypoxaemia and also
improves oxygenation
• Patient immobility. It is essential to avoid coughing and bucking
secondary to the intense stimulation from a rigid bronchoscope
deep in the bronchial tree
• The possibility of more rapid emergence since NMB can be
monitored throughout the procedure, allowing administration
of lower doses of IV anaesthetic
TRACHEOBRONCHIAL FOREIGN BODY
70. DISADVANTAGES OF CONTROLLED
VENTILATION
• Leads to overdistension of the obstructed lung which can
embarass the cardiovascular system and may cause
rupture of the alveoli resulting in tension pneumothorax.
• Positive airway pressure may cause distal migration and
dislodge the foreign body peripherally and may cause
failure to remove the foreign body.
71. IMPORTANT CONSIDERATIONS IN
CONTROLLING VENTILATION
• Adequate time is needed for exhalation
through the relatively high resistance
bronchoscope in order to prevent air trapping
and the associated barotrauma.
• Ventilation must be done in concert with the
bronchoscopist. Ventilation when the
bronchoscope is open will "ventilate" the room
72. • Excessive suctioning during the procedure can markedly
diminish oxygen concentration and also might induce
atelectasis.
• Therefore suction must be applied for short periods of
time ,which should be followed by lung inflation.
TRACHEOBRONCHIAL FOREIGN BODY
73. COMPLICATIONS
• Trauma to lips, teeth, base of tongue, epiglottis and larynx
• Severe cardiovascular embarrassment or even cardiac arrest may follow
tracheobronchial manipulation and suction;
This is due to a combination of hypoxia and reflex vagal stimulation. Hypoxia
aggravates vagal responses and increases the incidence of cardiac
arrhythmias.
• Laranygo/bronchospasm- ms. Relaxation,adequate ventilation.
• Pneumothorax, Pneumomediastinum , Pneumonia
• Atelectsasis
• Stridor secondary to subglottic oedema: Nebulized epinephrine 1:1000
should be administered in a dose of 0.5 ml /kg maximum 5 ml per
administration. I.V. dexamethasone produces more sustained relief of
stridor, but may take 1–2 h to act. Re-intubation may be required.
74. What About Flexible Bronchoscopy?
Excellent diagnostic tool
Minimal trauma, no general anesthesia
Reports of successful removal as well
American Thoracic Society still recommends rigid
bronchoscopy for removal
Flexible bronchoscopy can be performed with local anesthetic
topically and sedation in both children and adults
In smaller children who are unable to cooperate, general
anesthesia can be given using propofol and sevoflurane with
topical lignocaine
75. TO CONCLUDE
Normal CXR does not rule out Foreign Body
Bronchoscopy should be performed if foreign body aspiration is
suspected because it is better to do a negative bronchoscopy rather
missing a foreign body.
Not leaving small objects within reach of children.
No consensus from the literature as to which technique is optimal
Be ready and equipped
Don’t turn a non-obstructing FB into an obstructing one
Don’t miss the second FB- go back for another look
Not all FB’s can be removed endoscopically
76. REFRENCES
Miller’s anesthesia 7th edition.
Stoelting’s anesthesia and co-existing disease 5th edition.
Paediatric bronchoscopy:
Steve Roberts MBChB FRCA
Roger E Thornington MBBS FFA(SA) FRCA
Bronchoscopy by Chevalier Jackson.
PREFERRED ANAESTHETIC TECHNIQUE FOR TRACHEOBRONCHIAL
FOREIGN BODY - A OTOLARYNGOLOGIST’S PERSPECTIVE (INDIAN
JOURNAL OF ANAESTHESIA 2004)
REVIEW ARTICLE
CME
The Anesthetic Considerations of Tracheobronchial Foreign Bodies in Children: A
Literature Review of 12,979 Cases
Christina W. Fidkowski, MD,* Hui Zheng, PhD,† and Paul G. Firth, MBChB*‡
Article :Foreign bodies in the larynx and trachea BY J. N. G. Evans
Presently the death rates vary from 0.21% to 0.91% in different studies.
Since no symptom or sign is both highly sensitive and specific.
Add about the case not being an emergency/ patient not fasting. If the foreign body is
located in the trachea, the child is at risk for complete
airway obstruction and should be taken urgently to the
operating room. Conversely, the risk of complete airway
obstruction is less if the object is firmly lodged beyond the
carina. It is important to determine the type of foreign
body: Organic materials can absorb fluid and swell, oils
from nuts cause localized inflammation, and sharp objects
can pierce the airway. The time since the aspiration should
be established because airway edema, granulation tissue,
and infection may make retrieval more difficult with delayed presentations. A recently aspirated object may move
to a different position with coughing.