1. The document discusses various phase II conjugation reactions that transform drugs and xenobiotics into more polar and excretable metabolites. These include glucuronidation, sulphation, amino acid conjugation, glutathione conjugation, acetylation, and methylation. 2. Conjugation reactions involve the addition of endogenous hydrophilic groups such as glucuronic acid, sulphate, glycine, glutathione, acetyl, or methyl groups to drugs. This makes the drugs more water soluble and easier to eliminate from the body. 3. The major conjugation reactions, the functional groups they involve, the enzymes that catalyze the reactions, and common drug examples are described in detail in the document.