Titrimetric (volumetric) analysis is a quantitative analytical method where the volume of a solution of known concentration that reacts completely with the analyte is used to determine the concentration of the analyte. It involves a titrant of known concentration, an indicator to signal the endpoint, and standardization. Common titration reactions include acid-base neutralization, precipitation, complexation, and redox. Indicators are used to detect the endpoint visually through a color change. Primary standards have a known high purity and are used directly, while secondary standards are standardized against a primary standard. Burets and volumetric flasks are used to deliver and contain solutions accurately for titrations.
This presentation quotes various pharmaceutical calculations with examples. The following aspects like percentage calculations, alcoholic dilutions, Alligation method, proof spirit calculations, isotonicity adjustment, posology, temperature measurements, dialysis clearance, Pharmacokinetics calculations were covered with examples.
Teaching the history of pharmacy to young people is a challenge but it can be done if delivered in an interesting and engaging way. These slides summarize what I share with my students.
This presentation quotes various pharmaceutical calculations with examples. The following aspects like percentage calculations, alcoholic dilutions, Alligation method, proof spirit calculations, isotonicity adjustment, posology, temperature measurements, dialysis clearance, Pharmacokinetics calculations were covered with examples.
Teaching the history of pharmacy to young people is a challenge but it can be done if delivered in an interesting and engaging way. These slides summarize what I share with my students.
Patient Counseling is defined as providing medication information Orally or in written form to the patients or their representatives on directions of use, on side effects, precautions, storage, diet, life style modifications.
Patient Counseling is defined as providing medication information Orally or in written form to the patients or their representatives on directions of use, on side effects, precautions, storage, diet, life style modifications.
Unit 6 Water Content Determination and Moisture analysisMalou Mojares
To my CEU Senior Pharmacy QC 2 students.
Water Content Determination by Karl Fischer method, principle by Bunsen Reaction, types of KF method, Loss on Drying (LOD) moisture content determination.
This is useful to the chemical analysis persons. Tittration is one of the basic and standard method for quantitative chemical analysis. This describs the principles of titration, function of indicators, calculation of errors etc.
Titration - principle, working and applicationSaloni Shroff
A brief introduction to the titration technique used to know the concentration of unknown solutions. different types, indicators used and its application in foods and nutrition is also described.
Chemistry Lab Report on standardization of acid and bases. Karanvir Sidhu
I hope it might be helpful to you.
Email me on sidhu.s.karanvir@gmail.com to see more work.
Follow me at Linkedln
https://www.linkedin.com/in/karanvir-sidhu-b6995864/
In this presentation I have mentioned whatever the possible relevant content is required for this method
Citation Is done at the end of slide.
Content is up to date & true to my belief.
Thanks & Best Regards.
Anurag Pandey
B.Pharm (FACULTY OF PHARMACY, INVERTIS UNIVERSITY)
M.Pharm (INSTITUTE OF PHARMACY, NIRMA UNIVERSITY)
Email :- anurag.dmk05@gmail.com
Learning objectives
Introduction
Conditions For Volumetric Analysis
Terms In Volumetric Analysis
Primary Standard
Methods Of Expressing Concentrations In Volumetric Analysis
Types of Titration Methods
Classification Of Titrimetric Or Volumetric Methods
Conclusion
References
263778731218 Abortion Clinic /Pills In Harare ,sisternakatoto
263778731218 Abortion Clinic /Pills In Harare ,ABORTION WOMEN’S CLINIC +27730423979 IN women clinic we believe that every woman should be able to make choices in her pregnancy. Our job is to provide compassionate care, safety,affordable and confidential services. That’s why we have won the trust from all generations of women all over the world. we use non surgical method(Abortion pills) to terminate…Dr.LISA +27730423979women Clinic is committed to providing the highest quality of obstetrical and gynecological care to women of all ages. Our dedicated staff aim to treat each patient and her health concerns with compassion and respect.Our dedicated group ABORTION WOMEN’S CLINIC +27730423979 IN women clinic we believe that every woman should be able to make choices in her pregnancy. Our job is to provide compassionate care, safety,affordable and confidential services. That’s why we have won the trust from all generations of women all over the world. we use non surgical method(Abortion pills) to terminate…Dr.LISA +27730423979women Clinic is committed to providing the highest quality of obstetrical and gynecological care to women of all ages. Our dedicated staff aim to treat each patient and her health concerns with compassion and respect.Our dedicated group of receptionists, nurses, and physicians have worked together as a teamof receptionists, nurses, and physicians have worked together as a team wwww.lisywomensclinic.co.za/
The Gram stain is a fundamental technique in microbiology used to classify bacteria based on their cell wall structure. It provides a quick and simple method to distinguish between Gram-positive and Gram-negative bacteria, which have different susceptibilities to antibiotics
CDSCO and Phamacovigilance {Regulatory body in India}NEHA GUPTA
The Central Drugs Standard Control Organization (CDSCO) is India's national regulatory body for pharmaceuticals and medical devices. Operating under the Directorate General of Health Services, Ministry of Health & Family Welfare, Government of India, the CDSCO is responsible for approving new drugs, conducting clinical trials, setting standards for drugs, controlling the quality of imported drugs, and coordinating the activities of State Drug Control Organizations by providing expert advice.
Pharmacovigilance, on the other hand, is the science and activities related to the detection, assessment, understanding, and prevention of adverse effects or any other drug-related problems. The primary aim of pharmacovigilance is to ensure the safety and efficacy of medicines, thereby protecting public health.
In India, pharmacovigilance activities are monitored by the Pharmacovigilance Programme of India (PvPI), which works closely with CDSCO to collect, analyze, and act upon data regarding adverse drug reactions (ADRs). Together, they play a critical role in ensuring that the benefits of drugs outweigh their risks, maintaining high standards of patient safety, and promoting the rational use of medicines.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Basavarajeeyam is an important text for ayurvedic physician belonging to andhra pradehs. It is a popular compendium in various parts of our country as well as in andhra pradesh. The content of the text was presented in sanskrit and telugu language (Bilingual). One of the most famous book in ayurvedic pharmaceutics and therapeutics. This book contains 25 chapters called as prakaranas. Many rasaoushadis were explained, pioneer of dhatu druti, nadi pareeksha, mutra pareeksha etc. Belongs to the period of 15-16 century. New diseases like upadamsha, phiranga rogas are explained.
Basavarajeeyam is a Sreshta Sangraha grantha (Compiled book ), written by Neelkanta kotturu Basavaraja Virachita. It contains 25 Prakaranas, First 24 Chapters related to Rogas& 25th to Rasadravyas.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
2. Titrimetric methods
as an analytical method in which the volume of a
solution of known concentration consumed during an
analysis is taken as a measure of the amount of active
constituent in a sample analyzed
3. Analyte – or the active constituent in the sample
Titrant – solution of known concentration
Indicator – chemical which changes color at a point
equivalent quantities of analyte and titrant have
reacted
4. Stoichiometric point or Equivalence point – the
theoretical point at which equivalent amounts of each
have reacted
Endpoint – a sudden change apparent by use of
indicators
5. Standardization – determination of the exact
concentration of the solution
Standardized using 2 types of standards:
Primary standard – subs of known and high
degree of purity; used in direct standardization
Secondary standard – std. soln used in indirect
standardization
- std solution of known conc usually
standardized by primary std.
6. Requirements for Primary Standard:
1. High purity = 99.9%
2. Definite and known composition
3. Not affected by drying
4. Soluble in water
8. Example: standardization of HCL
Standardize titrimetrically using sodium carbonate of
known purity as a primary standard or
using standard NaOH as a secondary standard
16. Types of Titration:
DIRECT TITRATION – one titrant used, one volumetric
solution
RESIDUAL TITRATION – two titrants, two volumetric
solutions
1st VS – is added in excess
2nd VS – used to titrate the excess
17. Residual Titration - is used whenever the direct
titration is not practicable
- for compounds which react too slowly
with titrant
- poor solubility
- volatile substances are involved
Blank Determination – process of repeating the
procedure but omitting the sample
27. 1. Find the molarity of HCl soln. which contains the
volume of 2400 mL and also it contains 230 g of
HCl. MW of HCl=36.46
2. Find the normality of 20 g NaOH diluted to a volume
of 1L. MW of NaOH= 40
28. 3. Compute for normality of HCl that make use of a
primary standard (Na2CO3) that weighs 1.5 g. It
consumed 30 mL of HCl after titration. MW of
Na2CO3 = 106
4. Compute for normality of HCl using secondary
standard (NaOH) having a concentration of 2 N. It
consumed 35 mL of NaOH. The volume sample used
was 25 mL.
29. 5. A soln. with a final volume of 500 mL was prepared by
dissolving 25mL of methanol (density= 0.7914) in
chloroform. Calculate the molarity of methanol in the
soln. MW = 32
6. Calculate the normality of a NaCl soln. prepared by
dissolving 2.5 g of NaCl in water and then tapping it
off with more water to a total volume of 500 mL. MW
of NaCl= 58.44 g/mole
30. 7. What mass of oxalic acid, H2C2O4, is required to
make 250 mL of 0.05M soln.(MW=90)
8. Sulfamic acid is a primary standard that can be used
to standardize NaOH. What is the molarity if 34.26 mL
reacts with 0.3337 g of sulfamic acid. MW= 97
31. 9. What is the normality of H2SO4 containing 73.5 g/
500 mL of solution? MW of H2SO4= 98 g/mole
32. 10. The molecular wt. of NaOH is 40. How many grams
of NaOH pellets are needed to make 500 mL of 1.5 N
soln?
33. 11. Convert the following concentration as required:
0.5 M KOH to N
0.025 M H2SO4 to N
2 N NaCl to M
35. Standardization
determination of normality or molarity of solution
accomplished by the use of another standard solution
known as a SECONDARY STANDARD or by the use of
known purity substance as PRIMARY STANDARD
36. The wt. of substance chemically equivalent to 1 mL of
std. soln.
Express in mg/ mL
To get titer value:
N x meq wt.
1 meq X 60 g x 1000 mg
mL 1000 meq 1 g
= 60 mg/mL
37. Ex.
1. What would the titer value be of the soln. in terms of
CaCl2 of 0.05 N soln.? MW = 111
2. Compute for percent purity of 0.1 g sodium ascorbate
if the titer value is 9.905 mg/mL. It consumed 10 mL
thru direct titration with iodine.
39. Burets
Graduated glass tubes of uniform bore throughout the
whole length
Closed at the bottom by glass or stopcock
Volumes read at lower meniscus except highly colored
liquid
41. CHEMICAL REACTIONS USED IN TITRIMETRY
1. Neutralization (acid-base)
2. precipitation
3. complexation
4. redox
42. NEUTRALIZATION REACTION
a chemical process in which an acid (proton donor)
reacts with a base (proton acceptor)
the products are : water and salt
46. Commonly used pH indicators
Color Change
Indicator pH Range Acid Base
Malachite green 0.0 – 2.0 yellow green
Methyl Yellow 2.9 – 4.0 red yellow
Bromophenol blue 3.0 - 4.6 yellow blue
Methyl Orange 3.2 – 4.4pink yellow
Bromocresol green 4.0 -5.4 yellow blue
47. Methyl red 4.2 – 6.2 red yellow
Bromocresol purple 5.2 – 6.8 yellow purple
Bromothymol blue 6.0 – 7.6 yellow blue
Phenol red 6.8 – 8.2 yellow red
Cresol red 7.2 – 8.8 yellow red
Thymol blue 8.0 – 9.2 yellow blue
Phenolphthalein 8.0 – 10.0 colorless red
Thymolphthalein 9.3 – 10.5 colorless blue
48. Indicators:
Aqueous :
Phenolphthalein
Methyl orange
Methyl red
Strong Acid + Strong Base : php, MO, MR
Weak Acid + Strong base : php
Weak base + strong acid : MR
51. Standard Acid Solutions used in Acidimetry and
Alkalimetry
1. HCl – more preferable to sulfuric in the titration of
compounds that yield precipitate
2, Sulfuric Acid – preferable in hot titrations since HCl
will volatilize