Lymph nodes are small bean-shaped organs found mainly in the neck and trunk that play a vital role in filtering antigens and debris from lymph fluid and generating immune responses. They are structured with an outer cortex populated by B-lymphocytes, an inner paracortex containing T-lymphocytes and dendritic cells, and a medulla containing plasma cells that secrete antibodies. Lymph nodes filter lymph draining from tissues, catch tumor cells that have metastasized from primary cancers, and raise immune reactions against microbial infections.

1. LYMPH
NODE
By
K.Sanjay
I MSc Applied Microbiology

2. Structure of
Lymph node

3. Definition:
Lymph nodes are a group of small, bean-shaped organs
(2.6 cm in length) found mainly in
the neck and trunk of the human body.
They play vital roles in the filtration of antigens and
debris from Lymph (circulating
colourless watery fluid) and in the generation of
immune responses to pathogens.
Lymph nodes are often removed from cancer patients
as their filtration function catches
tumor cells metastasized (spread to other sites in the
body) from primary tumors.

4. Structure of Lymph Nodes
 Beneath the cortex is the Paracortex, which is
populated largely by T - lymphocytes and
also contains Interdigitating dendritic cells thought to
have migrated from tissues to the
node.
 The innermost layer of a lymph node, the Medulla is
more sparsely populated with
Lymphoid-lineage cells of those present, many are
Plasma cells actively secreting antibody
molecules.
 The Medulla in the core of the lymph node mainly
processes T - lymphocytes.

5. Drainage of fluid from blood stream
into the tissues.
Filtration of the lymph at the lymph
nodes.
Filtering blood.
Raise an immune reaction and fight
against microbial infections.
Functions of lymph node

6. Thank
you