The document discusses salivary gland diseases, focusing on sialadenitis (inflammation of the salivary glands) and salivary gland tumors. Sialadenitis can be caused by viruses, bacteria, or autoimmune disorders. The most common viral cause is mumps. Bacterial sialadenitis often results from ductal obstruction. Chronic sialadenitis is usually caused by Sjögren's syndrome. Common benign salivary gland tumors include pleomorphic adenoma, Warthin's tumor, and monomorphic adenomas. Malignant tumors include mucoepidermoid carcinoma and adenoid cystic carcinoma.

1. SALIVARY GLAND PATHOLOGY SMS 2044 Dr. Mohanad r. alwan

3. Micrograph showing chronic sialadenitis .

11. NORMAL HISTOLOGY

12. PLEOMORPHIC ADENOMA

16. PLEOMORPHIC ADENOMA A, Low-power view showing a well-demarcated tumor with adjacent normal salivary gland parenchyma. B, High-power view showing epithelial cells as well as myoepithelial cells found within a chondroid matrix material.

22. WARTHIN’S TUMOR A, Low-power view showing epithelial and lymphoid elements. Note the follicular germinal center beneath the epithelium. B, Cystic spaces separate lobules of neoplastic epithelium consisting of a double layer of eosinophilic epithelial cells based on a reactive lymphoid stroma.

25. MALIGNANT SALIVARY GLAND TUMORS

29. MUCOEPIDERMOID CARCINOMA A, Mucoepidermoid carcinoma showing islands having squamous cells as well as clear cells containing mucin. B, Mucicarmine stains the mucin reddish-pink. (Courtesy of Dr. James Gulizia, Brigham and Women's Hospital, Boston.)

32. ADENOID CYSTIC CARCINOMA Adenoid cystic carcinoma in a salivary gland. A, Low-power view. The tumor cells have created a cribriform pattern enclosing secretions. B, Perineural invasion by tumor cells.

36. SALIVARY GLAND TUMORS

37. HABIS QUESTION?????????????? Q1 . Mention the common types of salivary gland benign tumors with origin of each. Q2. Identify the histological feature for mucoepidermoid carcinoma