The document discusses why multicellular organisms require organ systems. It explains that single-celled organisms can carry out all life processes within a single cell by directly exchanging substances with the external environment. However, the cells of multicellular organisms are not all in direct contact with the environment and cannot independently obtain nutrients, oxygen, or remove wastes. Therefore, multicellular organisms have developed organ systems that work together to provide nutrients, oxygen, remove wastes, and perform other necessary functions for the organism. The main human organ systems listed are the digestive, circulatory, respiratory, excretory, reproductive, nervous, muscular and skeletal systems.