Intergenic regions are segments of DNA located between genes on chromosomes. They do not code for proteins but can contain regulatory sequences that influence the expression of adjacent genes. Introns are sequences within genes that are removed from precursor mRNA by RNA splicing. Recent research suggests intergenic regions may play roles in imprinting, cancers, and birth defects by containing control elements. Computational analysis is being used to better characterize intergenic regions and investigate their potential regulatory functions.