Diethyl ether can be prepared both in laboratories and on an industrial scale by the process called acid ether synthesis.
Ethanol is mixed with a strong acid like sulfuric acid (H2SO4).This strong acid dissociates in the aqueous environment producing H3O+(hydronium ions).
Diethyl Ether (DEE): Literature ReviewPratik Patel
Literature review for production of Diethyl ether. Literature Review includes History, Market Worldwide, Production capacity, properties, Selection of process.
Design of Primary & auxiliary equipment of Diethyl ether production plant. Process & mechanical design of Reactor, Heat exchanger, Distillation column.
Diethyl Ether (DEE): Literature ReviewPratik Patel
Literature review for production of Diethyl ether. Literature Review includes History, Market Worldwide, Production capacity, properties, Selection of process.
Design of Primary & auxiliary equipment of Diethyl ether production plant. Process & mechanical design of Reactor, Heat exchanger, Distillation column.
The dyestuff sector is one of the important segments of the chemicals industry in India, linked with a variety of sectors like textiles, leather, paper, plastics, printing inks and foodstuffs.
Unit operations and process involved in manufacturing of dyes and dye intermediates, wastewater characteristics of dyes and dye intermediates, effluent discharge standards, treatment technology for dye and dye intermediates, solid waste generation and Gaseous emissions.
this is the simple ppt about the manufacturing of H-acid which is used as the dye and dye intermediate in industry, and it is part of the syllabus in GTU sem-IV in subject of CPI-II.
Slides for the eLearning course Separation and purification processes in biorefineries (https://open-learn.xamk.fi) in IMPRESS project (https://www.spire2030.eu/impress).
Section: Distillation
Subject: 1.2 Flash distillation.
Advanced Oxidation Process for Industrial Water Treatment and Waste WaterUus Soedjak
Advanced Oxidation Process for Industrial Water Treatment and Waste Water is a liquid waste treatment technology which utilizes oxidation method using ozone gas. This technology is combined with ultraviolet light
The dyestuff sector is one of the important segments of the chemicals industry in India, linked with a variety of sectors like textiles, leather, paper, plastics, printing inks and foodstuffs.
Unit operations and process involved in manufacturing of dyes and dye intermediates, wastewater characteristics of dyes and dye intermediates, effluent discharge standards, treatment technology for dye and dye intermediates, solid waste generation and Gaseous emissions.
this is the simple ppt about the manufacturing of H-acid which is used as the dye and dye intermediate in industry, and it is part of the syllabus in GTU sem-IV in subject of CPI-II.
Slides for the eLearning course Separation and purification processes in biorefineries (https://open-learn.xamk.fi) in IMPRESS project (https://www.spire2030.eu/impress).
Section: Distillation
Subject: 1.2 Flash distillation.
Advanced Oxidation Process for Industrial Water Treatment and Waste WaterUus Soedjak
Advanced Oxidation Process for Industrial Water Treatment and Waste Water is a liquid waste treatment technology which utilizes oxidation method using ozone gas. This technology is combined with ultraviolet light
PRODUCTION OF METHYL TERTIARY BUTYL ETHER (MTBE)Aree Salah
this project submitted in partial fulfilment of the requirements for the degree of bachelor in science in Chemical engineering at Koya University.
The main purpose of our project is to describe and design the production of MTBE, and using it as an additive to gasoline in order to increase its quality.
We work at this plant to produce 112,200tons / year (112,200,000 kg/y) of methyl tertiary butyl ether (MTBE)
5 Production Methods of Benzene cyclic hydrocarbon first isolated by Faraday a natural component of crude oil can be produced using different methods Pyrolysis gasoline, coal tar, Catalytic Reforming, Toluene hydrodealkylation, Toluene disproportionation
alternative liquid fuels , ethanol and methanol production , application of ethanol and methanol , limitations and conclusion, contains all production of ethanol and methanol all over the world chart.
Production of ethyl acetate by esterificationrita martin
Ethyl acetate is synthesised via the Fischer esterification reaction from ethanol and acetic acid, typically in the presence of an acid catalyst such as concentrated sulfuric acid.
Corrosion Technology Forum – A two-day conclave discusses about corrosion prevention opportunities in the four major industries across geographies. Discusses various issues related to corrosion control, mitigation and methodologies to assess the damage due to corrosion.
Get 15% off on subscription now!! Chemical today magazine is a book for chemistry or chemical industry professionals which covers all influential topics, exotic concept &, fantastic appearance has attracted tons of readers over the globe.
Since the beginning of history recorded, human beings have sought to mask or augment their own body odor by applying perfume, which imitates nature’s pleasant smells. Many natural and man-made materials have been utilized or extracted to make perfumes. No perfume smells
Distillation is a method that can be utilized to take out an unadulterated liquid from a combination of liquids. It works when the liquids have distinguished boiling points. Distillation is typically used to detach ethanol, which is the alcohol in alcoholic drinks - from water.
Few things about Acetic acid you must knowrita martin
Acetic acid which is also known as Ethanoic acid is a colorless organic acid with chemicals formula C2H4O2 is liquid with strong and distinctive pungent and sour smell. Acetic acid got its name from a word “Acetum”, which is a Latin word for vinegar.
Tin is the 49th most rich element in the earth’s crust, having 2 parts per million compared with 75 parts per million for zinc, 50 parts per million for copper, and 14 parts per million for lead.
Calcium carbonate or CaCO3 is one of chemical compound found in the rocks as a mineral calcite and aragonite mostly particularly as a limestone, chalk or a marble.
A covalent bond is a chemical bond that involves sharing of pairs of electrons between atoms. These pairs of electrons are known as bonding pairs or shared pair
4 vital things about zinc that you should knowrita martin
Zinc designated with the chemical symbol of Zn and an atomic number of 30. The number of electrons per shell is 2, 8, 18 and 2. The two valence electrons of zinc are in charge of shaping bonds with different atoms, which is determined by its electron affinity, electro-negativity and ionization energies.
Toluene Biodegration Using Jet Loop Reactorrita martin
Toluene aromatic hydrocarbon solvent is a solvent in paints, lacquers, thinners, glues, correction fluid, carbon nanotubes and nail polish remover used as an octane booster in gasoline fuels
AIDS stands for: Acquired Immunodeficiency Syndrome HIV stands for: Human immunodeficiency virus AIDS is a disease of the human immune system caused by the HIV
Why the statue of liberty is colored blue greenrita martin
Statue of Liberty is its own special colour because of its unique environmental conditions. It's not a simple single reaction between copper and oxygen to generate a green oxide, like you may think. The copper oxide continues to react to make copper carbonates, copper sulphide, and copper sulphate.
6 methods of preparation of caustic sodarita martin
Sodium hydroxide, also known as caustic soda or lye, is an inorganic compound with the chemical formula NaOH. It is a white solid, and is a highly caustic metallic base and alkali salt. It is available in pellets, flakes, granules, and as prepared solutions at a number of different concentrations.
A solvent can be any substance, that turns into a solution by dissolving a solid, liquid, or gaseous solute. The solvent is usually a liquid, but can also be a solid or gas.
Milk is a cocktail of nearly 20 chemical compoundsrita martin
Milk is a nutritious liquid that is secreted by mammals and used to feed their young, and as food by human beings. Worldwide, dairy farms produced about 730 million tonnes of milk in 2011.
A brief information about the SCOP protein database used in bioinformatics.
The Structural Classification of Proteins (SCOP) database is a comprehensive and authoritative resource for the structural and evolutionary relationships of proteins. It provides a detailed and curated classification of protein structures, grouping them into families, superfamilies, and folds based on their structural and sequence similarities.
Nutraceutical market, scope and growth: Herbal drug technologyLokesh Patil
As consumer awareness of health and wellness rises, the nutraceutical market—which includes goods like functional meals, drinks, and dietary supplements that provide health advantages beyond basic nutrition—is growing significantly. As healthcare expenses rise, the population ages, and people want natural and preventative health solutions more and more, this industry is increasing quickly. Further driving market expansion are product formulation innovations and the use of cutting-edge technology for customized nutrition. With its worldwide reach, the nutraceutical industry is expected to keep growing and provide significant chances for research and investment in a number of categories, including vitamins, minerals, probiotics, and herbal supplements.
Multi-source connectivity as the driver of solar wind variability in the heli...Sérgio Sacani
The ambient solar wind that flls the heliosphere originates from multiple
sources in the solar corona and is highly structured. It is often described
as high-speed, relatively homogeneous, plasma streams from coronal
holes and slow-speed, highly variable, streams whose source regions are
under debate. A key goal of ESA/NASA’s Solar Orbiter mission is to identify
solar wind sources and understand what drives the complexity seen in the
heliosphere. By combining magnetic feld modelling and spectroscopic
techniques with high-resolution observations and measurements, we show
that the solar wind variability detected in situ by Solar Orbiter in March
2022 is driven by spatio-temporal changes in the magnetic connectivity to
multiple sources in the solar atmosphere. The magnetic feld footpoints
connected to the spacecraft moved from the boundaries of a coronal hole
to one active region (12961) and then across to another region (12957). This
is refected in the in situ measurements, which show the transition from fast
to highly Alfvénic then to slow solar wind that is disrupted by the arrival of
a coronal mass ejection. Our results describe solar wind variability at 0.5 au
but are applicable to near-Earth observatories.
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
Richard's aventures in two entangled wonderlandsRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
The increased availability of biomedical data, particularly in the public domain, offers the opportunity to better understand human health and to develop effective therapeutics for a wide range of unmet medical needs. However, data scientists remain stymied by the fact that data remain hard to find and to productively reuse because data and their metadata i) are wholly inaccessible, ii) are in non-standard or incompatible representations, iii) do not conform to community standards, and iv) have unclear or highly restricted terms and conditions that preclude legitimate reuse. These limitations require a rethink on data can be made machine and AI-ready - the key motivation behind the FAIR Guiding Principles. Concurrently, while recent efforts have explored the use of deep learning to fuse disparate data into predictive models for a wide range of biomedical applications, these models often fail even when the correct answer is already known, and fail to explain individual predictions in terms that data scientists can appreciate. These limitations suggest that new methods to produce practical artificial intelligence are still needed.
In this talk, I will discuss our work in (1) building an integrative knowledge infrastructure to prepare FAIR and "AI-ready" data and services along with (2) neurosymbolic AI methods to improve the quality of predictions and to generate plausible explanations. Attention is given to standards, platforms, and methods to wrangle knowledge into simple, but effective semantic and latent representations, and to make these available into standards-compliant and discoverable interfaces that can be used in model building, validation, and explanation. Our work, and those of others in the field, creates a baseline for building trustworthy and easy to deploy AI models in biomedicine.
Bio
Dr. Michel Dumontier is the Distinguished Professor of Data Science at Maastricht University, founder and executive director of the Institute of Data Science, and co-founder of the FAIR (Findable, Accessible, Interoperable and Reusable) data principles. His research explores socio-technological approaches for responsible discovery science, which includes collaborative multi-modal knowledge graphs, privacy-preserving distributed data mining, and AI methods for drug discovery and personalized medicine. His work is supported through the Dutch National Research Agenda, the Netherlands Organisation for Scientific Research, Horizon Europe, the European Open Science Cloud, the US National Institutes of Health, and a Marie-Curie Innovative Training Network. He is the editor-in-chief for the journal Data Science and is internationally recognized for his contributions in bioinformatics, biomedical informatics, and semantic technologies including ontologies and linked data.
Introduction:
RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is an important biological process for modulating eukaryotic gene expression.
It is highly conserved process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) causes sequence-specific degradation of mRNA sequences.
dsRNA-induced gene silencing (RNAi) is reported in a wide range of eukaryotes ranging from worms, insects, mammals and plants.
This process mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes.
What are small ncRNAs?
micro RNA (miRNA)
short interfering RNA (siRNA)
Properties of small non-coding RNA:
Involved in silencing mRNA transcripts.
Called “small” because they are usually only about 21-24 nucleotides long.
Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered).
Silence an mRNA by base pairing with some sequence on the mRNA.
Discovery of siRNA?
The first small RNA:
In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the
development of the worm C. elegans.
Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14.
Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions.
Types of RNAi ( non coding RNA)
MiRNA
Length (23-25 nt)
Trans acting
Binds with target MRNA in mismatch
Translation inhibition
Si RNA
Length 21 nt.
Cis acting
Bind with target Mrna in perfect complementary sequence
Piwi-RNA
Length ; 25 to 36 nt.
Expressed in Germ Cells
Regulates trnasposomes activity
MECHANISM OF RNAI:
First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces.
Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands.
The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it.
THE RISC COMPLEX:
RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA
Unwinding of double stranded Si RNA by ATP independent Helicase
Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA.
DICER: endonuclease (RNase Family III)
Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC)
One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute
ARGONAUTE PROTEIN :
1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA
2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity.
MiRNA:
The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .
Professional air quality monitoring systems provide immediate, on-site data for analysis, compliance, and decision-making.
Monitor common gases, weather parameters, particulates.
2. Diethyl Ether is an ether class of organic
compound. Basically, it has characteristics of
colourless, volatile, sweet solvent-like smelling
chemical. Diethyl Ether finds common use as a
solvent as well as in various household products.
It is a colourless, highly volatile flammable
liquid. It is commonly used as a solvent in
laboratories and as a starting fluid for some
engines. Diethyl ether is also a common solvent
for the Grignard reaction in addition to other
reactions involving organometallic reagents.
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3. It is used extensively in the chemical industry and as an
aerosol propellant. Diethyl ether was formerly used as a general
anaesthetic, until non-flammable drugs were developed, such as
halothane. It has been used as a recreational drug to cause
intoxication.
It has been used for decades as an energy source in various
countries like China, Japan, Korea, Egypt, and Brazil.
Domestically it can be produced from a variety of feedstocks,
including biogas from organic waste. Because of its lack of carbon-
to-carbon bonds, using Diethyl ether as an alternative to diesel
can virtually eliminate particulate emissions and potentially
negate the need for costly diesel particulate filters. Diethyl ether
has a high cetane number of 85-96 and is used as a starting fluid,
in combination with petroleum distillates for gasoline and Diesel
engines because of its high volatility and low flash point.
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4. Diethyl ether can be prepared both in
laboratories and on an industrial scale by the
process called acid ether synthesis.
Ethanol is mixed with a strong acid like sulfuric
acid (H2SO4).This strong acid dissociates in the
aqueous environment producing
H3O+(hydronium ions).
Later a hydrogen ion protonates the
electronegative oxygen atom of the ethanol,
giving the ethanol molecule a positive charge.
C2H5OH + H3O+ → C2H5OH2
+ + H2O
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5. A nucleophilic oxygen atom of unprotonated ethanol displaces a
water molecule from the protonated (electrophilic) ethanol
molecule, producing water, a hydrogen ion and diethyl ether.
C2H5OH2
+ + CH3CH2OH → H2O + H+ + C2H5OC2H5
This reaction must be carried out at temperatures lower than
150°C in order to ensure that an elimination product (ethylene) is
not a product of the reaction. At higher temperatures, ethanol will
dehydrate to form ethylene.
The reaction to make diethyl ether is reversible, so eventually, an
equilibrium between reactants and products is achieved. Getting a
good yield of ether, which in turn requires that ether is distilled out
of the reaction mixture before it reverts to ethanol.
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6. ThankYou
To read this article follow the link:
http://www.worldofchemicals.com/556/chemistry-articles/industrial-production-of-diethyl-ether.html
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