Hypopituitarism is an uncommon health condition where the pituitary gland does not produce hormones or fails to do so in sufficient amounts. The pituitary is an important endocrine gland, located at the bottom of the brain, responsible for secretion of hormones that influence almost every body part. To know more visit here: www.lazoi.com

1. HYPOPITUITARISM
Causes | Symptoms | Treatment | Diagnosis | preventions

2. What is Hypopituitarism ?
Hypopituitarism is an uncommon health condition where the
pituitary gland does not produce hormones or fails to do so in
sufficient amounts. The pituitary is an important endocrine gland,
located at the bottom of the brain, responsible for secretion of
hormones that influence almost every body part.
Hypopituitarism is marked by less production of pituitary hormones.
This low production hampers many body functions like, blood
pressure, reproduction and growth.

3. Causes of Hypopituitarism
 Head injuries
 Brain or pituitary tumors
 Brain surgery
 Radiation treatment
 Autoimmune inflammation (hypophysitis)
 Stroke
 Infections of the brain, such as meningitis
 Tuberculosis
 Severe loss of blood during childbirth, which may cause damage to
the front part of the pituitary gland (Sheehan syndrome or
postpartum pituitary necrosis)
 Genetic mutations resulting in impaired pituitary hormone
production

4. Symptoms of Hypopituitarism
 Tiredness
 Weight Loss
 Limited sex drive
 Increased sensitivity to cold
 Loss of appetite
 Iron deficiency
 Infertility
 Irregular periods, hot flashes, loss of pubic hair, less milk
production in breastfeeding women
 Loss of body or facial hair in men
 Short height of children

5. Diagnosis of Hypopituitarism
 Blood tests can help detect faults in hormones. They can easily
discover low levels of thyroid, sex hormones and tell if these low
levels are associated with insufficient pituitary hormone
production.
 Stimulation or dynamic testing test the body's secretion of
hormones after you've taken certain medications that might have
hampered the hormone production.
 MRI (Magnetic resonance imaging) can easily identify a pituitary
tumor.
 Vision tests can verify if growth of a pituitary tumor has an effect
on your vision.

6. Treatment of Hypopituitarism
 Oral Corticosteroids replace the adrenal hormones that are not
being produces because of a defiant ACTH (adrenocorticotropic
hormone).
 Levothyroxine replaces faulty thyroid hormone levels caused by
low TSH production.
 Sex hormones include testosterone (men) and a combination
of estrogen and progesterone (women). Testosterone levels are
checked through the skin with a patch, gel or injection. Estrogen
levels are checked with pills, gels or patches.
 Growth hormone helps children achieve normal height. Those
(adults) who have a growth hormone deficiency may benefit
from growth hormone replacement, but their height will not
increase.

7. Preventions of Hypopituitarism
Hypopituitarism occurring after delivery can be minimized by taking
proper obstetric care. For known patients of hypopituitarism, regular
monitoring and dose adjustment during periods of stress, infections
may be required; so regular follow-up is essential. Being prepared for
emergency situations can help to prevent adverse outcomes. It is
worth to consider wearing a medical alert bracelet or carrying an
identity card with details of disorder and medicines.

8. Risk factors of Hypopituitarism
 History of childhood cancer—some treatments can damage the
pituitary
 Infections
 Genetics
 Type 1 diabetes
 Sickle cell anemia
 Reduced blood volume or hypovolemia

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