Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease, is a progressive and fatal neurodegenerative disorder affecting motor neurons in the brain and spinal cord, leading to muscle weakness and paralysis. The disease is more prevalent in men aged 40-60, with possible causes including genetic mutations and elevated glutamate levels. Currently, there is no cure for ALS, and while symptom-relieving medications and therapies exist, the condition remains terminal.

2. Amyotrophic Lateral Sclerosis (ALS) is a neurological disease,
which is categorized under a group of disorders called motor
neuron diseases. This disorder is also referred to as Lou
Gehrig’s disease, after Lou Gehrig, a popular baseball player
who died of this disease in 1941. It is a progressive
neurodegenerative fatal disease, which affects neurons in the
brain and spinal cord. It can cause symptoms such as muscle
weakness, eventually leading to paralysis and death. This
disease more commonly affects men than women. People
between the age of 40 and 60 years are at a higher risk of
developing this disorder.

3. Several studies have been conducted and are being conducted
until now to determine the causes of Amyotrophic Lateral
Sclerosis. There have been theories presented though. Others
believe that the Lou Gehrig’s disease is a genetic disorder.
Studies also show that another probable cause of amyotrophic
lateral sclerosis is the mutations in the gene that produces the
SOD1 enzyme. Another possibility in terms of ALS causes that
researchers are looking into is the increased levels of glutamate.
This glutamate happens to be a chemical responsible for that
makes the transmission of messages between the neurons. This
is because patients suffering from the Lou Gehrig’s disease were
found to have elevated levels of glutamate. This isn't the case
with normal people who don’t have the said ailment. There are
those who think that the body’s autoimmune responses have
something to do with amyotrophic lateral sclerosis as well.

4. One of the early symptoms of the Lou Gehrig’s disease is
disordered articulation so if you know someone who is
struggling to speak and form certain words all of a
sudden, you should consider the possibility of
Amyotrophic Lateral Sclerosis. Check with a physician right
away. It’s the responsibility of those medical professionals
to confirm whether that individual is suffering from
amyotrophic lateral sclerosis or something else. Another
symptom that you should watch out for is if the person
involved has trouble walking or running and experiences
weakness in his/her muscles. That could be Amyotrophic
Lateral Sclerosis working its way through. Other motor
neuron degeneration symptoms include shortness of
breath, weakened reflexes and muscle cramps.

5. Sad to say, no cure or immediate prevention has
been discovered yet for Amyotrophic Lateral
Sclerosis, which makes it one of the fatal diseases
ever to hit humanity. There may be medications
being offered to relieve the symptoms including
muscle stiffness, cramping, eating difficulties and
others but that’s just it. Some patients are being
given physiotherapy and special equipments like
the ventilator.

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