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HOW THE BRAIN WORKS




  DR. JAMES M. ALO
I. Anatomy/Physiology
2


    A.    Neuron- highly specialized for the processing and
          transmission of cellular signals


         1.        Basic component of the nervous sy.
         2.        Composed of cell body, axon & dendrites
              a.    Cell body = center of metabolism
              b.    Axon =long fibers > conduct impulses away from the cell
                    body; usually 1 axon for each cell body
              c.    Dendrites = short, unsheathed fibers> receive nerve
                    impulses> transmit to cell body
                                                   drjAlo
3


    3. Myelin sheath – covering that protects nerve fiber>
       facilitates> speed of impulse conductor
         a. Axon & dendrite – may/may not have myelin
               sheath




        b.   Most axons leaving the CNS – heavily myelinated
             w/ schwann cells
        c.   Gaps in myelin sheath – termed Nodes of Ranvier
                                        drjAlo
4


    4. Primary fxn – transmission of nerve impulses
        a.   Afferent (sensory) n. – transmit impulses from
             peripheral receptors } CNS



        b.   Efferent (motor) n. – conduct impulses from CNS
        c.   Action potentials travel along axons} end of
             nerve fiber }impulse is transmitted across
             junction bet. nerve cells (synapse) }chemical
             interaction
                                       drjAlo
5


    5. Neuroglia – glial cells
        a.   Provide support,
        b.   Nourishment and
        c.   Protection for neurons




                                      drjAlo
6


    B. PNS } contains cranial
       nerves, spinal nerves,
       autonomic nervous
       system(unconscious
       reflexes), sympathetic
       division (accelerates
       activity), &
       parasympathetic
       division(slows body
       processes).
                                drjAlo
7


    C. CNS contains:
      1.   Cerebrum – divided into: left right hemisphere}
           longitudinal fissure




                                        drjAlo
8


    a. Frontal lobes
         Precentral   gyrus – contralateral movement; face, arm, leg,
          trunk
         Broca’s area – dominant hemisphere } respon.> formation of
          words
         Supplementary motor area – contralateral head & eye
          turning
         Prefrontal area- personality, initiative
         Paracentral lobule- contralateral inhibition of bladder &
          bowel


                                             drjAlo
9


    b. Parietal lobes
       Postcentralgyrus – body sensations; temp, touch,
        pressure, pain }from opposite side of the body
       Dominant parietal lobe- wernickes’ speech area,
        auditory & visual aspects> comprehensions are
        integrated
               Responsible for skills { handle numbers & calculations
       Nondominant  parietal lobe- concept of body image &
        awareness of external envi{ ability to construct shapes


                                                  drjAlo
10


     c. Occipital lobes – visual center; comprehension of
        written word
     d. Temporal lobes
        Dominant   hearing of language; taste, smell
        Memory

        Wernicke’s   speech area – recognition of language




                                         drjAlo
11


     2. Basal ganglia – reg & integr skeletal voluntary &
        autonomic motor activity originating in cerebral cortex
     3. Diencephalon – connects the cerebrum & brain stem;
        contains several small structures, the most important of
        w/c are the thalamus & hypothalamus
       a. Thalamus – relay station for discrimination of sensation
         }received from periphery>several nuclei in the thalamus,
         each w/ specific fxns} such as: integration of sensory stimuli
         necessary for abstract thinking & reasoning, vision, hearing;
         relay station for fibers going to limbic system

                                            drjAlo
12


      Hypothalamus- responsible for maintaining
      momeostasis} thru the secretion of hormones & central
      control of ANS
        Controls vital fxn: water balance, BP, sleep, appetite, temp
        Affects some emotional responses ] pleasure/fear
        Control center for pituitary fxn
        Affects both divisions of the ANS




                                           drjAlo
13


     c. Limbic system –responsible for controlling various
        functions in the body. Structures of this system
        include the hippocampus, hypothalamus, and
        thalamus
        Fig.




                                       drjAlo
14


     4. Brain stem- contains; midbrain, pons & medulla
       oblangata, extending from the cerebral
       hemispheres to the foramen magnum @ the base of
       the skull
       a.   Contains nuclei- 5,6,7,8th Cnerves & ascending
            sensory & descending motor tracts
       b.   Contains vital center- respiratory, vasomotor &
            cardiac fxn
       c.   Reticular formation – relays sensory of info; controls
            vasomotor/respiratory activity
                                           drjAlo
15


     5. Ventricular system & CSF – supports & cushions
       CNS
        Removes metabolic wastes
        Compensatory mechanisms for ICVolume/pressure

        Produces 55 cc/d of CSF; 130-150cc amt ave in sy




                                      drjAlo
16


     6. Cranial meninges
        Dura mater – dense, fibrous, outermost layer serves as
         periosteum for Cnerves
        Arachnoid mater
            Delicate, avascular membrane lying under dura
            Surrounds brain loosely
            Subarachnoid space contains; CSF, arteries & veins
            Contains arachnoid granulations that enable CSF } pass from
             subarachnoid space>venous system
          Pia mater
            Most delicate inner meningeal layer
            Barrier system


                                                   drjAlo
17


     7. Cerebellum – control of: muscle motion, balance,
       coordination; trunk mobility & equilibrium
        Spinal   cord – communications link bet CNS & PNS
          Ascending    pathways ] transmit
               Sensory information
          Descending    pathways] relay
               Motor instrtuctions




                                              drjAlo
18




     Thank You.




             drjAlo

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How the brain works

  • 1. HOW THE BRAIN WORKS DR. JAMES M. ALO
  • 2. I. Anatomy/Physiology 2 A. Neuron- highly specialized for the processing and transmission of cellular signals 1. Basic component of the nervous sy. 2. Composed of cell body, axon & dendrites a. Cell body = center of metabolism b. Axon =long fibers > conduct impulses away from the cell body; usually 1 axon for each cell body c. Dendrites = short, unsheathed fibers> receive nerve impulses> transmit to cell body drjAlo
  • 3. 3 3. Myelin sheath – covering that protects nerve fiber> facilitates> speed of impulse conductor a. Axon & dendrite – may/may not have myelin sheath b. Most axons leaving the CNS – heavily myelinated w/ schwann cells c. Gaps in myelin sheath – termed Nodes of Ranvier drjAlo
  • 4. 4 4. Primary fxn – transmission of nerve impulses a. Afferent (sensory) n. – transmit impulses from peripheral receptors } CNS b. Efferent (motor) n. – conduct impulses from CNS c. Action potentials travel along axons} end of nerve fiber }impulse is transmitted across junction bet. nerve cells (synapse) }chemical interaction drjAlo
  • 5. 5 5. Neuroglia – glial cells a. Provide support, b. Nourishment and c. Protection for neurons drjAlo
  • 6. 6 B. PNS } contains cranial nerves, spinal nerves, autonomic nervous system(unconscious reflexes), sympathetic division (accelerates activity), & parasympathetic division(slows body processes). drjAlo
  • 7. 7 C. CNS contains: 1. Cerebrum – divided into: left right hemisphere} longitudinal fissure drjAlo
  • 8. 8 a. Frontal lobes  Precentral gyrus – contralateral movement; face, arm, leg, trunk  Broca’s area – dominant hemisphere } respon.> formation of words  Supplementary motor area – contralateral head & eye turning  Prefrontal area- personality, initiative  Paracentral lobule- contralateral inhibition of bladder & bowel drjAlo
  • 9. 9 b. Parietal lobes  Postcentralgyrus – body sensations; temp, touch, pressure, pain }from opposite side of the body  Dominant parietal lobe- wernickes’ speech area, auditory & visual aspects> comprehensions are integrated  Responsible for skills { handle numbers & calculations  Nondominant parietal lobe- concept of body image & awareness of external envi{ ability to construct shapes drjAlo
  • 10. 10 c. Occipital lobes – visual center; comprehension of written word d. Temporal lobes  Dominant hearing of language; taste, smell  Memory  Wernicke’s speech area – recognition of language drjAlo
  • 11. 11 2. Basal ganglia – reg & integr skeletal voluntary & autonomic motor activity originating in cerebral cortex 3. Diencephalon – connects the cerebrum & brain stem; contains several small structures, the most important of w/c are the thalamus & hypothalamus a. Thalamus – relay station for discrimination of sensation }received from periphery>several nuclei in the thalamus, each w/ specific fxns} such as: integration of sensory stimuli necessary for abstract thinking & reasoning, vision, hearing; relay station for fibers going to limbic system drjAlo
  • 12. 12  Hypothalamus- responsible for maintaining momeostasis} thru the secretion of hormones & central control of ANS  Controls vital fxn: water balance, BP, sleep, appetite, temp  Affects some emotional responses ] pleasure/fear  Control center for pituitary fxn  Affects both divisions of the ANS drjAlo
  • 13. 13 c. Limbic system –responsible for controlling various functions in the body. Structures of this system include the hippocampus, hypothalamus, and thalamus  Fig. drjAlo
  • 14. 14 4. Brain stem- contains; midbrain, pons & medulla oblangata, extending from the cerebral hemispheres to the foramen magnum @ the base of the skull a. Contains nuclei- 5,6,7,8th Cnerves & ascending sensory & descending motor tracts b. Contains vital center- respiratory, vasomotor & cardiac fxn c. Reticular formation – relays sensory of info; controls vasomotor/respiratory activity drjAlo
  • 15. 15 5. Ventricular system & CSF – supports & cushions CNS  Removes metabolic wastes  Compensatory mechanisms for ICVolume/pressure  Produces 55 cc/d of CSF; 130-150cc amt ave in sy drjAlo
  • 16. 16 6. Cranial meninges  Dura mater – dense, fibrous, outermost layer serves as periosteum for Cnerves  Arachnoid mater  Delicate, avascular membrane lying under dura  Surrounds brain loosely  Subarachnoid space contains; CSF, arteries & veins  Contains arachnoid granulations that enable CSF } pass from subarachnoid space>venous system  Pia mater  Most delicate inner meningeal layer  Barrier system drjAlo
  • 17. 17 7. Cerebellum – control of: muscle motion, balance, coordination; trunk mobility & equilibrium  Spinal cord – communications link bet CNS & PNS  Ascending pathways ] transmit  Sensory information  Descending pathways] relay  Motor instrtuctions drjAlo
  • 18. 18 Thank You. drjAlo