This document summarizes efforts by NASA's Dryden Flight Research Center to change its project execution culture through implementing Critical Chain Project Management tools and philosophies. The Dryden Center has around 550 civil service employees and 600 contractors working on 40+ active projects of varying sizes from multiple customers. Previously, the culture was characterized by unclear priorities, budget-driven staffing, poorly defined work, projects often in delay, and severe multi-tasking leading to delays, overruns, and workforce burnout. The desired new culture focuses on reducing multi-tasking and stress, improving on-time performance, and allowing more time for training through implementing techniques like staggered milestones, identifying and resolving issues quickly, and using buffers to set priorities.