This document provides information about the mineral Hingula (cinnabar) in several languages. It describes cinnabar's chemical composition, typical physical properties like color and hardness, common locations where it is found, traditional and artificial methods of preparation, various medical uses in formulations, and ways to identify it mineralogically. The key points are that cinnabar is a bright red mineral composed of mercury and sulfur, used historically as a pigment and source of mercury, and in Ayurveda it has rejuvenating, strength-building and aphrodisiac properties.
Sandhana kalpana is the preparation of self generated alcohol. All the preparations that are resulting from FERMENTATION procedure come under SANDHANA KALPANA.
Sandhana kalpana is a special technique to prepare most effective medicines like Asava and Aristas. The medicines prepared through Sandhana kriya are quick in action, long shelf life, palatability and has nutritive value.The self-generated alcohol is the key factor behind the success of Sandhana kalpana.
This is the second part of presentation regarding definitions in Rasa shastra. An attempt is made to clarify the definitions in more clear way also useful images are added to further improvise the presentation.
Sandhana kalpana is the preparation of self generated alcohol. All the preparations that are resulting from FERMENTATION procedure come under SANDHANA KALPANA.
Sandhana kalpana is a special technique to prepare most effective medicines like Asava and Aristas. The medicines prepared through Sandhana kriya are quick in action, long shelf life, palatability and has nutritive value.The self-generated alcohol is the key factor behind the success of Sandhana kalpana.
This is the second part of presentation regarding definitions in Rasa shastra. An attempt is made to clarify the definitions in more clear way also useful images are added to further improvise the presentation.
For a rasa Shastra student its necessary to have knowledge of Parada Bandhas. In this presentation bandhas are explained according to various authors and detailed description is narrated according to Rasa Ratna Samucchaya the most accepted book of Rasa Shastra. I hope this presentation will help the students of Rasa Shastra in having better summarised knowledge of bandhas.
Kajjali (mercury- sulphur bond) is one of the basic kalpana in Rasa shastra. Its use in various formulations is well described in rasa text. Although is single use is quite limited in clinical practice, this presentation reveals few of the uses of kajjali in single form.
• Rasashastra deals with metallic, mineral and poisonous drugs.
• These drugs are pharmaceutically processed and rendered fit for internal administration.
• For the various processing of rasa uparasadi dhatus and for the preparation of medicines, specific apparatuses called ‘Yantras’ are needed.
• Metals and minerals are required to undergo certain processes like shodhana, jarana, marana, satwapatana etc before they could be administered into the body and all these processes could only be achieved with the help of yantras.
• For exploring and utilizing the knowledge of Rasasastra, a better understanding of yantras is needed.
• Textbooks of Ayurvediya Rasasastra including Rasatarangini, Rasaratna samuchaya, Rasarnavam and Rasendra Choodamani have been the sources of literature along with other published works on Rasasastra.
For a rasa Shastra student its necessary to have knowledge of Parada Bandhas. In this presentation bandhas are explained according to various authors and detailed description is narrated according to Rasa Ratna Samucchaya the most accepted book of Rasa Shastra. I hope this presentation will help the students of Rasa Shastra in having better summarised knowledge of bandhas.
Kajjali (mercury- sulphur bond) is one of the basic kalpana in Rasa shastra. Its use in various formulations is well described in rasa text. Although is single use is quite limited in clinical practice, this presentation reveals few of the uses of kajjali in single form.
• Rasashastra deals with metallic, mineral and poisonous drugs.
• These drugs are pharmaceutically processed and rendered fit for internal administration.
• For the various processing of rasa uparasadi dhatus and for the preparation of medicines, specific apparatuses called ‘Yantras’ are needed.
• Metals and minerals are required to undergo certain processes like shodhana, jarana, marana, satwapatana etc before they could be administered into the body and all these processes could only be achieved with the help of yantras.
• For exploring and utilizing the knowledge of Rasasastra, a better understanding of yantras is needed.
• Textbooks of Ayurvediya Rasasastra including Rasatarangini, Rasaratna samuchaya, Rasarnavam and Rasendra Choodamani have been the sources of literature along with other published works on Rasasastra.
The Sanskrit word "Parpati" denotes a thin flake like preparation.
"Parpati" indicates a preparation which is thin, brittle and has a shape of thin Paapad.
Rasendra Mangal in 8th century by Acharya Nagarjun has mentioned use of Parpati in Kushtha Roga Later in 11th century Acharya Chakrapani Dutt in Chakradutt mentioned its use in Grahani Roga
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
CDSCO and Phamacovigilance {Regulatory body in India}NEHA GUPTA
The Central Drugs Standard Control Organization (CDSCO) is India's national regulatory body for pharmaceuticals and medical devices. Operating under the Directorate General of Health Services, Ministry of Health & Family Welfare, Government of India, the CDSCO is responsible for approving new drugs, conducting clinical trials, setting standards for drugs, controlling the quality of imported drugs, and coordinating the activities of State Drug Control Organizations by providing expert advice.
Pharmacovigilance, on the other hand, is the science and activities related to the detection, assessment, understanding, and prevention of adverse effects or any other drug-related problems. The primary aim of pharmacovigilance is to ensure the safety and efficacy of medicines, thereby protecting public health.
In India, pharmacovigilance activities are monitored by the Pharmacovigilance Programme of India (PvPI), which works closely with CDSCO to collect, analyze, and act upon data regarding adverse drug reactions (ADRs). Together, they play a critical role in ensuring that the benefits of drugs outweigh their risks, maintaining high standards of patient safety, and promoting the rational use of medicines.
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
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Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
4. Introduction
•7th mineral of Sadharana rasa.
•Identified as cinnabar.
•Chemically red sulphide of mercury.
•86.2% of Hg & 13.5% S
•Generally found in a massive granular or earthy form and is
bright scarlet to brick red in colour.
•Occasionally crystals with adamantine luster.
•Ancient times it has been mined for use as pigment as well
as for mercury.
•Crushed cinnabar is roasted in rotary furnace to get quick
silver(Hg).
5. Occurance
•Ores found in US, Japan, Spain, Italy, France, Germany and
Japan.
•Not found in India.
•Artificially prepared in laboratories.
6. Mineralological properties
Cleavage: {1010} Perfect
Color:
Lead gray, Brown, Brown pink, Vermilion, Gray.
Density: 8.1
Diaphaneity: Transparent to translucent to opaque
Fracture: Brittle - Sectile - Brittle fracture with slightly sectile shavings
possible.
Crystal system
Triagonal trapezohedral
Habit: Massive - Uniformly indistinguishable crystals forming large
masses.
Hardness: 2-2.5 - Gypsum-Finger Nail
Luminescence:
Non-fluorescent.
Luster: Adamantine
Streak: bright red
12. According to rasa tarangini
2types:-1.khanija
2.krithrima
Places of availability
Spain,Italy,France,Germany,Brazil,China,Japan,Russia,Americ
a,Iran,British columbia of Canada.In the city of Korea in Asia
minor,Hingula has been available since 3000yrs&has been in-
use in colour-industry
13. Sodhanam
bhavana in any of the following liquid for7times
Ginger juice
Lakuja rasa
Mesha dugdha&amla varga
Nimbu rasa
18. Methods adopted
•Urdhwa patanam
•Adhapathanam
Required quantity of hingula is taken in clean khalva and
subjected to bhavana with ardraka swarasa for 7 times.
It is dried and taken in lower pot of clean urdhva patana or
vidyadhara yantra.Another pot is kept on top and sandhilepa
is done followed by enabling condensation of mercury
vapours by placing a wet cloth over the top of upper pot.
Mercury is collected in the upper pot
It is collected washed and used as hingulotha parada.
19. • Dose:-1/2-1gunja
• Amayika prayoga
Hingula along with
Jatiphala+pippali+sunti+ahiphena+su.gandaka
—sukrasrita vata
Pippali+ativisha+madhu+ginger juice---jwara
Jatiphala+lavanga+indrayava+karpura—
amatisara with ruja
Jatiphala+ahiphena+musta+karpura+indrayava
—amatisara
Guduchi satva—amlapitta
20. Artificial preparation of Hingula
• 8part S+42part Hg ground &put in mrdhanga
yantra
• Rotate well by holding its handle for getting
slakshna curna
• While opening the yantra we will get dusara
varnabha curna
• Put this powder in a stali&close with another&do
sandhi lepana
• Put into fire&give heat in orderly
manner(increasing order)
21. Contd…
• Will get hingula from the neck portion of adha
stali&bottom of the urdha stali
(R.T.)
Another method
• 1part Hg+4 part S in iron vessel&give mrudwagni
• Resultant mass break into small pieces&fill this in
kachakupi
• Put in valuka yantra&give mrudwagni for 1 day
• Then increase heat in orderly manner for 7 days
• 7th day will get beautiful hingula
(A.P.)
22. Important yogas
• Amruthamanjari rasa Anandabhairava rasa
• Kamagnisandeepana rasa Kshethrapala rasa
• Jwaradumaketu rasa Jwara murari rasa
• Mruta sanjeevana rasa Mrutyunjaya rasa
• Sree siddha daradamrutam(R.T.) Hinguleswara rasa
• Hinguliya manikya rasa(R.T) Sreesiddhahinguleswara
rasa(R.T.)
• Daradamrutha malahara Darada vati
• Hinguladya malahara Hingulamruta malahara
24. Contd…
• Fracture Sub concoidal to uneven
• Elasticity Imperfectly sectile
• Hardness 2
• Gravity 8.1
• Fusibility 1.5
• Cinnabar is formed from hydrothermal solutions at
relatively low temperature & is found in veins &
impregations in areas of hot springs of volcanic activity