This document provides guidance from the WHO on preventing and managing wound infections. It outlines three key principles: do not close infected wounds, do not close contaminated wounds that are over six hours old, and use antibiotic prophylaxis and surgical debridement to prevent infections. It then describes three protocols: 1) wound toilet and surgical debridement to clean wounds, 2) management of tetanus-prone wounds with vaccination and immunoglobulin, and 3) antibiotic prophylaxis and treatment for wounds at high risk of infection.