The document discusses various drugs used to treat diabetes, including their mechanisms of action, side effects, and classifications. It notes that lactic acidosis is common with phenformin, rosiglitazone acts as a PPAR gamma agonist but not by increasing insulin secretion, hypokalemia can occur if insulin is given rapidly for diabetic ketoacidosis, and metformin can cause vitamin B12 deficiency. Common side effects of thiazolidinadiones include water retention and weight gain.

1. Insulin,Oral
Hypoglycemic
agents

2. Lactic acidosis is common
in Phenformin
Rosiglitazone mechanism of
action is Acts as PPAR
gamma agonist
Rosiglitazone does not act
by increasing insulin
secretion

3. Hypokalemia will happen if
insulin alone is given rapidly in
diabetic ketoacidosis
Tolbutamide is the most potent
among antidiabetic drugs are
the insulin secretogogue
Metformin drug causes Vitamin
B12 Deficiency

4. Common side effect of
thiazolidinadiones is Water
retention with weight gain
Promlintide is Synthetic
amylin analoge
2nd generation
hypoglycemic drugs are all
except Tolbutamide

5. Incretin like function is
seen in Exenatide
If a patient with severe
hyperglycemia is given i.v.
insulin, can occur
Hypokalemia
Glargine is a long – acting
insulin

6. Tolbutamide acts by
increasing Insulin
Secretion
Acarbose drugs does not
cause hypoglycemia
Alpha - glucosidase
inhibitor is Acarbose

7. Acarbose is used (with diet or
diet and other medications) to
TREAT TYPE 2 DIABETES
condition in which the body
does not use insulin normally
and therefore Cannot Control
The Amount Of Sugar In The
Blood and it is Alpha –
glucosidase inhibitor