This document discusses genetic variation and intercultural management of grape. It notes that genetic variation arises from mechanisms like mutation, sexual reproduction, and genetic drift. Grape is grown in three agro-climatic zones in India - subtropical, hot tropical, and mild tropical regions. Various pruning, training, irrigation, fertilization, and pest and disease management practices are used depending on the region. Grape varieties grown vary by region and include Perlette, Thompson Seedless, Anab-e-Shahi, and Sharad Seedless. Methods to increase genetic variation through hybridization and polyploidy are also summarized.