This document discusses genetic mapping and its various medical applications. It describes how genetic mapping is used to identify the positions of genes within genomes and locate genes associated with certain traits or diseases. Specifically, it mentions two studies: one that used genetic mapping in mice to identify the pituitary tumor transforming gene's role in liver fibrosis, and another that mapped genes responsible for leaf rust resistance in wheat. The document also outlines some of genetic mapping's utility in medical fields like assessing disease predispositions, genetically engineering crop resistance, and examining fetal genetics during high-risk pregnancies.

1. GENETIC MAPPING
By
Juana Hoyos Palacio
Medicine Student

4. Introduction
The technique
shows the position
of genes in the
genome.
Inquire aobut the
information that
they have

5. Pituitary tumor transforming
gene as a novel regulatory
factor of liver fibrosis
Life sciences.
(2015, april 15).

6. Pituitary tumor transforming gene as a
novel regulatory factor of liver fibrosis
Scientists found by an
exhaustive investigation that
the pituitary tumor
transforming gene (PTTG)
has an important function in
liver diseases.

7. Pituitary tumor transforming gene as a
novel regulatory factor of liver fibrosis
They used mice
and mapping
genes technique
to find them in
their loci. After
that, they
searched for a
real correlation
between both
genes.

8. Pituitary tumor transforming gene as a
novel regulatory factor of liver fibrosis
Results showed that the
mice with knockout PTTG
might prevent the
development of liver
fibrosis
Liver fibrosis

9. Pituitary tumor transforming gene as a
novel regulatory factor of liver fibrosis
Student criterion
This investigation is interesting because it
shows the relationship between a gene that
has the correlation with the brain and liver
diseases.
From now on scientist have more tools to
continue investigating genes, and other
implications they may have
This is helps demonstrate that almost every
component in the body is correlated, and
that patients need to be evaluated as a
whole

10. Molecular mapping
of leaf rust
resistance genes in
the wheat line Yu
356-9

11. Molecular mapping of leaf rust
resistance genes in the wheat line Yu
356-9
The answer resides in the
genetic information that each
organism has. Some
researchers from china had
curiosity about the special
resistance that has the wheat
line 356-9 to leaf rust
pathotypes
Have you ever wondered
why some plants are more
resistant to pathogens than
others?

12. Molecular mapping of leaf rust
resistance genes in the wheat line Yu
356-9
Scientists exposed several
genes from a type of
wheat to leaf rust
pathotypes. All of them
except Yu 356-9 were
infected.

13. Molecular mapping of leaf rust
resistance genes in the wheat line Yu
356-9
They used mapping genes strategy to
find the place where the gene was.
Later they tried to determine if there
were any relationship between the
gene and the neighbors’ gene.
The purpose was to know more about
it and learn from it.

14. Molecular mapping of leaf rust
resistance genes in the wheat line Yu
356-9
Student criterion
This is useful because with the
modifications that the gene has,
we can eat more healthy food. In
this way we prevent the inducing
of apoptosis becoming from the
food with nonresistance genes to
pathogens.

15. Medical
utility

16. Medical utility
As well, molecular
mapping can be used
to check the
predisposition
people has about
specific genes that
develop diseases.

17. Medical utility
The technique is also
used in genetic therapy
with crops to find any
weakness that their DNA
might have and
"correct" the mistake;
resulting in genetic
resistance.

18. Medical utility
In high-risk pregnancy,
it allows to check the
genetic material of the
fetus; giving
information to the
doctors about the
baby´s condition and
what possible treatment
to follow if necessary.

19. Bibliografia
• HAN Lui-sha, LI Zai-feng (2015), “ Molecular mapping of
leaf rust resistance genes in the wheat line Yu 356-9”,
Journal of integrative agriculture, China. From:
http://www.sciencedirect.com/science/article/pii/S20953
11914609643
• Vyacheslav Buko, Belonovskaya Elena (2015), “pituitaty
tumor transforming gene as a novel regulatory factor of
lives fibrosis”, life sciences, Poland. From:
http://www.sciencedirect.com/science/article/pii/S00243
20515002301
• Martinez Sanches, Lina Maria. Biologia molecular, 8 ,
edicion, Medellin UPB . Fac.Medicina.

20. I LOVE BOB