Recombination sequences in DNA may help determine the order of genes on chromosomes. This allows estimation of relative distances between genes and localization of genes. A study genotyped nearly 700,000 markers in the genomes of about 9,000 individuals to identify genes associated with polycystic ovary syndrome (PCOS). The study did not find genes regulating testosterone production in the ovaries, which was previously thought to be a major factor in PCOS. Another study mapped gene activity in the first few days of human embryo development from fertilization to provide insight into the "ignition key" that switches on human development.

4. Recombination sequences
may constitute a
convenient way to
determine the order of
the genes on the
cromosome.
That makes possible to
estimate the relative
distances between genes,
finding its correct
localization.

5. August 19,2015
DATA MINING DNA FOR POLYCYSTIC
OVARY SYNDROME GENES

6. Polycystic ovary syndrome
affects 7-10 % of
reproductive-age
worldwide
Characteristic symptoms
•Increased male pattern hair
growth
•Weight gain
•Irregular periods
•Infertility
DATA MINING DNA FOR POLYCYSTIC
OVARY SYNDROME GENES

7. They genotyped nearly
700000 markers across the
genomes of aprox. 9000
individual dna samples
DATA MINING DNA FOR POLYCYSTIC
OVARY SYNDROME GENES

8. For many years, researchers had
been thinking that is testosterone
produced by the ovary the major
problem in PCOS
The study didn´t find signals or
genes regulating testosterone
DATA MINING DNA FOR POLYCYSTIC
OVARY SYNDROME GENES

9. STUDENT´S OPINION
The information
provided by studies like
this, facilitates the
development of more
efficient treatments for
the syndrome

10. September 4, 2015
SCIENTISTS MAP GENE ACTIVITY
OF HUMAN EMBRYO'S FIRST DAYS

11. The first study to map all
the genes that are
activated in the first few
days of embryo
development from the
point of fertilization
Is like finding the “ignition
key” that switches on
human development
SCIENTISTS MAP GENE ACTIVITY OF
HUMAN EMBRYO'S FIRST DAYS

12. Human egg fertilization sparks
a cascade of genetic activity
After 1 day ,
the single
cells becomes
two
After 2days ,
there are four
cells
After 3 days ,
there are
eight cells

13. It still being a mistery the order
in wich genes are activated
following fertilization
SCIENTISTS MAP GENE ACTIVITY OF
HUMAN EMBRYO'S FIRST DAYS

14. STUDENT´S OPINION
Approaches on gene regulation
from the moment of
fertilization found in this study
are useful for genetics and
invite us to interest and inquire
more about it
Approaches on gene regulation
from the moment of
fertilization found in this study
are useful for genetics and
invite us to interest and inquire
more about it

15. MEDICAL UTILITY
Genetic mapping is a key
element in determining
congenital diseases

16. Knowing the location
of a gene responsible
of any disease allows
the realization of a
specific therapy for
the disease
MEDICAL UTILITY

17. MEDICAL UTILITY
Pcos is a high incidence
disease in worldwide
women. Studies about it
are needed to improve the
way it is treated and the
quality life of those women

18. MEDICAL UTILITY
Factors found in genetic
mapping after fertilization
might be used in
reprogramming cells into
stem ones could maximize
the treatment of infertility

19. BIBLIOGRAPHY
• PIERCE, Benjamin A. Genética un enfoque conceptual. 2ª, edición. Madrid:
editorial Médica Panamericana.2006. 172-173p.
• STRACHAN, Andrew; READ, Andrew P. Genética humana. 3° edición.
México: Mc Graw Hill Interamericana.2004.400p.
• MARTINEZ SÁNCHEZ, Lina María. Biología molecular libro de clase. 8 ed.
Medellín: Editorial UPB. 2015. 185-191 p.
• ScienceDaily,. (2015). Data mining DNA for polycystic ovary syndrome
genes: Scientists identify PCOS susceptibility that appears to be unique to
European women. Retrieved 11 September 2015, from
http://www.sciencedaily.com/releases/2015/08/150819103654.htm
• Medical News Today (2015). Scientists map gene activity of human
embryo's first days. Medical News Today. Retrieved 10 September 2015,
from http://www.medicalnewstoday.com/articles/299061.php