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Unit- I, Lecture- 7
Importance, of minerals in animal
health and production
Dr. Pankaj Kumar Singh
Department of Animal Nutrition
Bihar Animal Sciences University, Patna, India
e-mail: vetpank@gmail.com ; 7909079625
BIHAR ANIMAL SCIENCES UNIVERSITY
Bihar Veterinary College, Patna
Department of Animal Nutrition
• Inorganic component of diet
• Represented by total ash
• Perform essential functions & must be present in food
• In animal tissues and feeds, minerals are present in
varying amounts and concentrations.
• Total body mineral  Ca (46%)
P (29%)
 Mg, Na, K, Cl, S (25%)
 micro minerals (3%)
Minerals
• Essential Minerals:
– Major/macro- 07
– Minor/Micro-15
• Major/macro:
– The seven minerals that are present in high
concentration (>70 mg/kg live weight) are termed
as major minerals.
– Calcium (Ca),Phosphorus (P), Magnesium (Mg),
Sodium (Na), Potassium (K), Chlorine (Cl), Sulphur
(S)
Minerals
• Trace elements or Micro minerals are those minerals that are present
in low concentration (<70 mg/kg live weight)
• but are physiologically equally important.
• The following fifteen trace elements are essential to fullfil
physiological functions in the body
Minerals
Iron (Fe) Chromium (Cr)
Copper (Cu) Fluorine (F)
Cobalt (Co) Tin (Su)
Manganese (Mg) Vanadium (V)
Zinc (Zn) Silicon (Si)
Iodine (I) Nickel (Ni)
Selenium (Se) Arsenic (As)
Molybdenum (Mo)
I. Structural: form structural components of body organs and
tissues,
eg. as calcium, phosphorus and magnesium in bones
and teeth; and phosphorus and sulfur in muscle proteins.
II. Physiological: in body fluids and tissues as electrolytes
concerned with the maintenance of osmotic pressure, acid–base
balance, membrane permeability and transmission of nerve
impulses.
eg. sodium, potassium, chlorine, calcium and magnesium in
the blood, cerebrospinal fluid and gastric juice
III. Catalytic: act as catalysts in enzyme and endocrine systems, as
integral and specific components of the structure of metallo
enzymes and hormones or as activators (coenzymes) within
those systems.
Minerals: General functions
Minerals
• Regulatory: minerals regulate cell replication and
differentiation;
– eg. calcium ions influence signal transduction and selenocysteine
influences gene transcription, The pivotal metabolic role of thyroxine has
been attributed to the influence of triiodothyronine on gene
transcription
• Component of biomolecules: of biologically important
compounds
– Iron in haemoglobin
– Cobalt in vitamin B12
– Iodine in the hormone thyroxine
Minerals: General functions
Dietary sources of Mineral
–Concentrate feed and forages
–Mineral supplements such as bone meal, mineral
mixture, common salt, calcite, shell grit etc.,
–Drinking water – minor source
–Soil contamination of herbage source for grazing
animals.
• Mineral req. are more difficult to define (w.r.t. organic nutrients) due
to involvement of so many factors.
• Strong interrelationship/ interaction among minerals causes
increased or decreased utilization.
• Presence of antimetal compounds in food
E.g. oxalates, phytates etc.
• Actual amount of mineral in diet affect utilization.
Higher concentration reduced absorption efficiency
• Mineral status of animal.
Iron deficient animal will have better efficient absorption than that
with higher iron reserve
• Form of mineral: salt (generally sulphates are more available than
oxides)
• Animal factors: Age, sex, productivity level, genetic make up
Factors affecting mineral req./ utilization
• Second most abundant nutrient element (after N) in body.
Functions of Ca
• Structural component of body (Skeleton and teeth): 99% of the
calcium in the body is present in the bones and teeth.
• controls the excitability of nerves and muscles
• required for normal clotting of blood
Functions of P
• occurs in close association with calcium in bone.
• vital role in energy metabolism (ATP)
• key role in metabolic reaction of carbohydrate, protein and lipids
(phosphorylated intermediate compounds).
• component of phospholipids, which are important in lipid transport
and metabolism as constituent of cell membranes.
• constituent of RNA and DNA.
• component of many enzyme systems.
Calcium & Phosphorus
Ca & P in bones:
• Total mineral in animal body 3%
• Out of total mineral 70% Ca & P
• Majority of Ca (99%) and P (80%) in bones (store of Ca & P) and teeth.
• In bones exist in ratio of 2: 1
• Moisture and fat free bone= 36% Ca and 17% P
Adult bone
Water 45%
Ash (minerals) 25%
Protein 20%
Fat 10%
Calcium & Phosphorus
• Blood cells are devoid of Ca
• Plasma Ca in two forms: soluble ionised form (60% of total) and
bound with proteins (albumin and plasma protein)
• Blood Ca9-11 mg/dl
• Whole blood P 35-45 mg/dl (most of it present in cells
• Plasma iP 4-9mg/dl
• Blood concentration of P is more dependent on dietary manipulation
as compared to that of Ca.?????
Calcium & Phosphorus
Regulation of calcium metabolism
• Whenever blood calcium level decreases below the normal,
parathyroid gland is stimulated to secrete parathormone. This
hormone mobilizes calcium from the bone and also facilitates
reabsorption of calcium in the kidney.
• It also increases calcium absorption in the small intestine by
increasing the synthesis of 1,25 dihydroxy cholecalciferol (active form
of vitamin D) from 25 hydroxy cholecalciferol in the kidneys, which in
turn increases the synthesis of calcium binding protein resulting in
increased calcium absorption.
• High level of blood calcium stimulates the secretion of calcitonin,
which has antagonistic action to that of parathormone.
Calcium
General Mineral Nutrition of Livestock

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General Mineral Nutrition of Livestock

  • 1. Unit- I, Lecture- 7 Importance, of minerals in animal health and production Dr. Pankaj Kumar Singh Department of Animal Nutrition Bihar Animal Sciences University, Patna, India e-mail: vetpank@gmail.com ; 7909079625 BIHAR ANIMAL SCIENCES UNIVERSITY Bihar Veterinary College, Patna Department of Animal Nutrition
  • 2. • Inorganic component of diet • Represented by total ash • Perform essential functions & must be present in food • In animal tissues and feeds, minerals are present in varying amounts and concentrations. • Total body mineral  Ca (46%) P (29%)  Mg, Na, K, Cl, S (25%)  micro minerals (3%) Minerals
  • 3. • Essential Minerals: – Major/macro- 07 – Minor/Micro-15 • Major/macro: – The seven minerals that are present in high concentration (>70 mg/kg live weight) are termed as major minerals. – Calcium (Ca),Phosphorus (P), Magnesium (Mg), Sodium (Na), Potassium (K), Chlorine (Cl), Sulphur (S) Minerals
  • 4. • Trace elements or Micro minerals are those minerals that are present in low concentration (<70 mg/kg live weight) • but are physiologically equally important. • The following fifteen trace elements are essential to fullfil physiological functions in the body Minerals Iron (Fe) Chromium (Cr) Copper (Cu) Fluorine (F) Cobalt (Co) Tin (Su) Manganese (Mg) Vanadium (V) Zinc (Zn) Silicon (Si) Iodine (I) Nickel (Ni) Selenium (Se) Arsenic (As) Molybdenum (Mo)
  • 5. I. Structural: form structural components of body organs and tissues, eg. as calcium, phosphorus and magnesium in bones and teeth; and phosphorus and sulfur in muscle proteins. II. Physiological: in body fluids and tissues as electrolytes concerned with the maintenance of osmotic pressure, acid–base balance, membrane permeability and transmission of nerve impulses. eg. sodium, potassium, chlorine, calcium and magnesium in the blood, cerebrospinal fluid and gastric juice III. Catalytic: act as catalysts in enzyme and endocrine systems, as integral and specific components of the structure of metallo enzymes and hormones or as activators (coenzymes) within those systems. Minerals: General functions
  • 7. • Regulatory: minerals regulate cell replication and differentiation; – eg. calcium ions influence signal transduction and selenocysteine influences gene transcription, The pivotal metabolic role of thyroxine has been attributed to the influence of triiodothyronine on gene transcription • Component of biomolecules: of biologically important compounds – Iron in haemoglobin – Cobalt in vitamin B12 – Iodine in the hormone thyroxine Minerals: General functions
  • 8. Dietary sources of Mineral –Concentrate feed and forages –Mineral supplements such as bone meal, mineral mixture, common salt, calcite, shell grit etc., –Drinking water – minor source –Soil contamination of herbage source for grazing animals.
  • 9. • Mineral req. are more difficult to define (w.r.t. organic nutrients) due to involvement of so many factors. • Strong interrelationship/ interaction among minerals causes increased or decreased utilization. • Presence of antimetal compounds in food E.g. oxalates, phytates etc. • Actual amount of mineral in diet affect utilization. Higher concentration reduced absorption efficiency • Mineral status of animal. Iron deficient animal will have better efficient absorption than that with higher iron reserve • Form of mineral: salt (generally sulphates are more available than oxides) • Animal factors: Age, sex, productivity level, genetic make up Factors affecting mineral req./ utilization
  • 10. • Second most abundant nutrient element (after N) in body. Functions of Ca • Structural component of body (Skeleton and teeth): 99% of the calcium in the body is present in the bones and teeth. • controls the excitability of nerves and muscles • required for normal clotting of blood Functions of P • occurs in close association with calcium in bone. • vital role in energy metabolism (ATP) • key role in metabolic reaction of carbohydrate, protein and lipids (phosphorylated intermediate compounds). • component of phospholipids, which are important in lipid transport and metabolism as constituent of cell membranes. • constituent of RNA and DNA. • component of many enzyme systems. Calcium & Phosphorus
  • 11. Ca & P in bones: • Total mineral in animal body 3% • Out of total mineral 70% Ca & P • Majority of Ca (99%) and P (80%) in bones (store of Ca & P) and teeth. • In bones exist in ratio of 2: 1 • Moisture and fat free bone= 36% Ca and 17% P Adult bone Water 45% Ash (minerals) 25% Protein 20% Fat 10% Calcium & Phosphorus
  • 12.
  • 13. • Blood cells are devoid of Ca • Plasma Ca in two forms: soluble ionised form (60% of total) and bound with proteins (albumin and plasma protein) • Blood Ca9-11 mg/dl • Whole blood P 35-45 mg/dl (most of it present in cells • Plasma iP 4-9mg/dl • Blood concentration of P is more dependent on dietary manipulation as compared to that of Ca.????? Calcium & Phosphorus
  • 14. Regulation of calcium metabolism • Whenever blood calcium level decreases below the normal, parathyroid gland is stimulated to secrete parathormone. This hormone mobilizes calcium from the bone and also facilitates reabsorption of calcium in the kidney. • It also increases calcium absorption in the small intestine by increasing the synthesis of 1,25 dihydroxy cholecalciferol (active form of vitamin D) from 25 hydroxy cholecalciferol in the kidneys, which in turn increases the synthesis of calcium binding protein resulting in increased calcium absorption. • High level of blood calcium stimulates the secretion of calcitonin, which has antagonistic action to that of parathormone. Calcium