This document discusses the importance of minerals in animal health and production. It provides information on the classification of minerals as major/macro or trace/micro minerals. The major minerals are calcium, phosphorus, magnesium, sodium, potassium, chlorine and sulfur. Trace minerals include iron, copper, cobalt, manganese, zinc, iodine, selenium and molybdenum. Minerals perform important structural, physiological, catalytic and regulatory functions in the body. Calcium and phosphorus are particularly significant as they make up the majority of mineral content in bones and teeth. The document outlines factors that influence mineral requirements and utilization.
Advances in vitamin & mineral nutrition in livestockRameswar Panda
feeding management cannot be ignored under any circumstances. This presentation depicts the tangential and burning points related to the role and significance of Vitamins and minerals for the livestock
Advances in vitamin & mineral nutrition in livestockRameswar Panda
feeding management cannot be ignored under any circumstances. This presentation depicts the tangential and burning points related to the role and significance of Vitamins and minerals for the livestock
This slides contains information on precision feeding in dairy cattle and requirement of energy, protein, fat, minerals and vitamins of a dairy cattle during lactation. Precision feeding protects reproductive health and milk production while reducing the nutrient loss in manure.
Only 25-35% of the N in feed goes into milk, with the rest excreted in feces and urine.
Dairy diets often have 120-160% of the P and that the excess is excreted in the manure.
Cost of feed can be reduced.
Precision feeding helps to improve water quality
Improving the efficiency of use of feed N.
Reduce SARA condition.
Controlled-release urea in dairy cattle feed.
Straw treatment-Ammoniation.
Reducing Enteric Methane Losses from Ruminant Livestock.
Phase feeding in dairy cattle.
Feeding bypass fat in early lactation.
Use of chelated minerals in dairy animals.
Nutraceuticals in dairy animal precision feeding.
10. Use of area specific mineral mixture to precise dairy animal nutrition.
11. TMR in precision nutrition.
12. Manipulation of dietary CAD.
Five distinct feeding phases can be defined to attain optimum production, reproduction and health of dairy cows:
Early lactation—0 to 70 days (peak milk production) after calving (postpartum).
Peak DM intake—70 to 140 days (declining milk production) postpartum.
Mid and late lactation—140 to 305 days (declining milk production) postpartum.
Dry period—60 days before the next lactation.
Transition or close-up period—14 days before to parturition.
Feed top quality forage.
Make sure the diet contains adequate amounts of CP, DIP and UIP.
Increase grain intake at a constant rate after calving.
Consider adding fat (0.4-0.6 kg/cow/day) to diets.
Allow constant access to feed.
Minimize stress conditions.
Limit urea to 80-160g/day.
Buffers, such as Na bicarbonate alone or in combination with Mg oxide (rumen pH)
In Transition period
Increase grain feeding, so cows are consuming 4.5-6 kg grain/day at calving (1% of B.wt)
Increase protein in the ration to between 14 - 15 % of the ration DM
Limit fat in the ration to 0.1kg. High fat feeding will depress DM intake.
Maintain 2.5-4kg of long hay in the ration to stimulate rumination.
Feed a low-Ca ration (< 0.20%, reduce Ca intake to 14 to 18 g/d)
Also, feed a diet with a negative dietary electrolyte balance (-10 to -15meq/100 g DM) may alleviate milk fever problems
Niacin (to control ketosis) and/or anionic salts (to help prevent milk fever) should be included in the ration during this period.
"عسى ان تكون علما ينتفع به"
Role of trace minerals in poultry nutrition
Difference between organic and inorganic source of trace minerals
Poultry nutrition
Different methods to calculateEnergy requirement for maintenance, growth, pregnancy, and lactation in ruminants
Sri Venkateswara veterinary university, Animal nutrition, Vishnu Vardhan Reddy
Importance of Vitamins and Minerals for Dairy Cattle. The article written by Mr. Rakesh Kumar, Marketing Director, Growel Agrovet Private Limited, has been published in Dairy Planner magazine, March – 2021 edition.
Rdp,udn and kinetics, Rumen undegradable protein, Rumen degradable protein and their kinetics, Sri Venkateswara veterinary university, Animal nutrition, Vishnu Vardhan Reddy
Protein quality determination in monogastric animals, we can determine which protein is better in case of monogastric animals, Sri Venkateswara veterinary university, Animal nutrition, Vishnu Vardhan Reddy
This slides contains information on precision feeding in dairy cattle and requirement of energy, protein, fat, minerals and vitamins of a dairy cattle during lactation. Precision feeding protects reproductive health and milk production while reducing the nutrient loss in manure.
Only 25-35% of the N in feed goes into milk, with the rest excreted in feces and urine.
Dairy diets often have 120-160% of the P and that the excess is excreted in the manure.
Cost of feed can be reduced.
Precision feeding helps to improve water quality
Improving the efficiency of use of feed N.
Reduce SARA condition.
Controlled-release urea in dairy cattle feed.
Straw treatment-Ammoniation.
Reducing Enteric Methane Losses from Ruminant Livestock.
Phase feeding in dairy cattle.
Feeding bypass fat in early lactation.
Use of chelated minerals in dairy animals.
Nutraceuticals in dairy animal precision feeding.
10. Use of area specific mineral mixture to precise dairy animal nutrition.
11. TMR in precision nutrition.
12. Manipulation of dietary CAD.
Five distinct feeding phases can be defined to attain optimum production, reproduction and health of dairy cows:
Early lactation—0 to 70 days (peak milk production) after calving (postpartum).
Peak DM intake—70 to 140 days (declining milk production) postpartum.
Mid and late lactation—140 to 305 days (declining milk production) postpartum.
Dry period—60 days before the next lactation.
Transition or close-up period—14 days before to parturition.
Feed top quality forage.
Make sure the diet contains adequate amounts of CP, DIP and UIP.
Increase grain intake at a constant rate after calving.
Consider adding fat (0.4-0.6 kg/cow/day) to diets.
Allow constant access to feed.
Minimize stress conditions.
Limit urea to 80-160g/day.
Buffers, such as Na bicarbonate alone or in combination with Mg oxide (rumen pH)
In Transition period
Increase grain feeding, so cows are consuming 4.5-6 kg grain/day at calving (1% of B.wt)
Increase protein in the ration to between 14 - 15 % of the ration DM
Limit fat in the ration to 0.1kg. High fat feeding will depress DM intake.
Maintain 2.5-4kg of long hay in the ration to stimulate rumination.
Feed a low-Ca ration (< 0.20%, reduce Ca intake to 14 to 18 g/d)
Also, feed a diet with a negative dietary electrolyte balance (-10 to -15meq/100 g DM) may alleviate milk fever problems
Niacin (to control ketosis) and/or anionic salts (to help prevent milk fever) should be included in the ration during this period.
"عسى ان تكون علما ينتفع به"
Role of trace minerals in poultry nutrition
Difference between organic and inorganic source of trace minerals
Poultry nutrition
Different methods to calculateEnergy requirement for maintenance, growth, pregnancy, and lactation in ruminants
Sri Venkateswara veterinary university, Animal nutrition, Vishnu Vardhan Reddy
Importance of Vitamins and Minerals for Dairy Cattle. The article written by Mr. Rakesh Kumar, Marketing Director, Growel Agrovet Private Limited, has been published in Dairy Planner magazine, March – 2021 edition.
Rdp,udn and kinetics, Rumen undegradable protein, Rumen degradable protein and their kinetics, Sri Venkateswara veterinary university, Animal nutrition, Vishnu Vardhan Reddy
Protein quality determination in monogastric animals, we can determine which protein is better in case of monogastric animals, Sri Venkateswara veterinary university, Animal nutrition, Vishnu Vardhan Reddy
Introduction to Minerals and essential nutrients DHANANJAY PATIL
A Comprehensive Introduction to Minerals and essential nutrients- Biochemical functions, source, RDA, disease states. This will give readers a overall insight to this topic.
this matter useful for B.V.Sc student . Minerals ,their deficiency and their roles also available in this matter it is also useful for Animal nutritionist .
metabolism is the sum total of tissue activity as considered in terms of physicochemical changes associated with and regulated by the availability, utilization and disposal of protein, fat, carbohydrate, vitamins, minerals, water and the influences which the endocrines exert on these processes”
The mineral elements constitutes only small proportion of body weight.
Minerals perform several vital functions which are absolutely essential for the existance of the organism.
These include calcification of bone, blood coagulation, neuromuscular irritability, acid-base equilibrium, fluid balance and osmotic regulation.
this presentation describes the various types of minerals, their roles, deficiency symptoms. this presentation also describe the criteria of essentially of the minerals.
Physiological and nutritional significance of minerals paper 3.pptxSanatsawant
1.Introduction :
“Minerals in food are the elements present in food that are required by our body to develop and function properly.”
2.Nutritionally important minerals are
a. Sodium: A) Nutritional Significance :-
Sodium is taken in diet along with chloride in the form of common salt.
Sodium is found in table salt, baking soda, monosodium glutamate, egg, meat, fish, dairy products, poultry, olives & pickled food.
The Recommended dietary allowance of sodium is in
Child :- 0.3 - 2.5 mg/day
Adult :- 1.3 - 5.0 mg/day
B) Physiological significance :-
Body needs small amount of sodium to help maintain normal B.P. & normal function of muscles and nerves.
Sodium is important in maintaining fluid balance as the concentration of sodium is directly related to the osmotic pressure of plasma .
b.Potassium:A) Nutritional Significance :-
K + is a major intracellular cation.
Normal concentration of K + in plasma is 3.5 – 5.0 Meq. per litre.
Main sources of potassium are banana, orange, potatoes, sweet potatoes, watermelon ,mushrooms, dried plums etc.
B) Physiological Significance :-
It influences muscular activity.
It is involved in regulation of acid-base balance.
It plays an important role in cardiac function.
c.Chloride: A) Nutritional Significance :-
Cl- is taken in the diet along with Na+ in the form of common salt.
Plasma volume of Cl- depends upon Na+ & HCO3- levels in plasma.
Low Na+ level is associated with low Cl- .
High Na+ level is associated with high Cl- .
High HCO3- is associated with low Cl- .
Low HCO3- is associated with high Cl- .
The sources of chloride are table salt, tomatoes, Olives , meats etc.
The recommended daily allowance of chloride is
In children = 1500 - 2300 mg /day
In Adults = 1800 - 2300 mg/day
B) Physiological Significance :-
It is important for the production of HCI in the gastric juice .
It is an essential part of digestive (stomach) juices .
Chloride is needed to keep the proper balance of body fluids .
d.Phosphorus:Nutritional Significance : -
Phosphorous is an important mineral for teeths and bones .
It is most widely distributed in foods such as milk, cheese, egg, nuts, meat etc.
About 85% of phosphorous in the body is stored in bones and teeths .
Recommended daily allowance of Phosphorous is,
In Childrens :- 1200 mg/day ( because bone formation and development is more rapid at this stage of life)
In Adults :- 700 mg/day
B) Physiological significance : -
It is used for the maintenance of bones and teeth.
It is used to produce DNA & RNA.
Phosphorous is required by the body for Creating, utilizing and storing energy.
e.Nutritional Significance :-
Calcium is an important mineral for bones & teeth .
It is widely distributed in foods such as milk, cheese, egg, beans, cabbage, etc.
Of the total Ca absorbed in the body 45 % bound to protein 45 % exists as diffusible Ca2+ & 10 % is complexed with anions.
Absorption of Ca depends upon Ca:P ratio & also vitamin D that promotes absorption of Ca from food .
R
The minerals form only a small portion of the total body weight. They form only 7% of the composition of human body.
Many of these minerals are widely distributed in foods so that a well-balanced diet will supply them in sufficient quantities.
The mineral elements present in the animal body may be classified into 2 groups:
1.Principal elements(macro nutrients)
2.Trace elements(micro nutrients)
Mineral notes for medical students
Insha Allah i will uploaded anatomy, physiology, biomechanics and biochemistry, pharmacology related notes
My YouTube channel
https://www.youtube.com/@DrphysioO
India is facing scarcity of feed and fodder for feeding of livestock and poultry, which limits livestock productivity. Feed and Fodder development Platform is very essential to deal with scarcity of quality feed and fodder in Livestock. Accelerated fodder production and their preservation, collection, storage and utilization of agro-industrial by-products like rice and wheat straw using bailing, cubing etc. and fodder bank may help in dealing with scarcity of fodder. Ration balancing at farmer`s doorstep, regular quality of feed and fodder will be very helpful in sustaining livestock productivity.
Antibiotic growth promoter have played a critical role in contributing to the economic effectiveness of animal production as feed supplements at sub-therapeutic doses, to improve growth and feed conversion efficiency, and to prevent infections However, injudicious use of antibiotic growth promoter leads to development of antimicrobial resistance and antibiotic residue posing a potential threat to human health.
Organic acids, probiotics, prebiiotic, enzymes, phytobiotics, bacteriophage etc. are effective antibiotic alternatives to promote animal growth performance in poultry, swine, and beef and dairy production.
Earliest Galaxies in the JADES Origins Field: Luminosity Function and Cosmic ...Sérgio Sacani
We characterize the earliest galaxy population in the JADES Origins Field (JOF), the deepest
imaging field observed with JWST. We make use of the ancillary Hubble optical images (5 filters
spanning 0.4−0.9µm) and novel JWST images with 14 filters spanning 0.8−5µm, including 7 mediumband filters, and reaching total exposure times of up to 46 hours per filter. We combine all our data
at > 2.3µm to construct an ultradeep image, reaching as deep as ≈ 31.4 AB mag in the stack and
30.3-31.0 AB mag (5σ, r = 0.1” circular aperture) in individual filters. We measure photometric
redshifts and use robust selection criteria to identify a sample of eight galaxy candidates at redshifts
z = 11.5 − 15. These objects show compact half-light radii of R1/2 ∼ 50 − 200pc, stellar masses of
M⋆ ∼ 107−108M⊙, and star-formation rates of SFR ∼ 0.1−1 M⊙ yr−1
. Our search finds no candidates
at 15 < z < 20, placing upper limits at these redshifts. We develop a forward modeling approach to
infer the properties of the evolving luminosity function without binning in redshift or luminosity that
marginalizes over the photometric redshift uncertainty of our candidate galaxies and incorporates the
impact of non-detections. We find a z = 12 luminosity function in good agreement with prior results,
and that the luminosity function normalization and UV luminosity density decline by a factor of ∼ 2.5
from z = 12 to z = 14. We discuss the possible implications of our results in the context of theoretical
models for evolution of the dark matter halo mass function.
(May 29th, 2024) Advancements in Intravital Microscopy- Insights for Preclini...Scintica Instrumentation
Intravital microscopy (IVM) is a powerful tool utilized to study cellular behavior over time and space in vivo. Much of our understanding of cell biology has been accomplished using various in vitro and ex vivo methods; however, these studies do not necessarily reflect the natural dynamics of biological processes. Unlike traditional cell culture or fixed tissue imaging, IVM allows for the ultra-fast high-resolution imaging of cellular processes over time and space and were studied in its natural environment. Real-time visualization of biological processes in the context of an intact organism helps maintain physiological relevance and provide insights into the progression of disease, response to treatments or developmental processes.
In this webinar we give an overview of advanced applications of the IVM system in preclinical research. IVIM technology is a provider of all-in-one intravital microscopy systems and solutions optimized for in vivo imaging of live animal models at sub-micron resolution. The system’s unique features and user-friendly software enables researchers to probe fast dynamic biological processes such as immune cell tracking, cell-cell interaction as well as vascularization and tumor metastasis with exceptional detail. This webinar will also give an overview of IVM being utilized in drug development, offering a view into the intricate interaction between drugs/nanoparticles and tissues in vivo and allows for the evaluation of therapeutic intervention in a variety of tissues and organs. This interdisciplinary collaboration continues to drive the advancements of novel therapeutic strategies.
Introduction:
RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is an important biological process for modulating eukaryotic gene expression.
It is highly conserved process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) causes sequence-specific degradation of mRNA sequences.
dsRNA-induced gene silencing (RNAi) is reported in a wide range of eukaryotes ranging from worms, insects, mammals and plants.
This process mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes.
What are small ncRNAs?
micro RNA (miRNA)
short interfering RNA (siRNA)
Properties of small non-coding RNA:
Involved in silencing mRNA transcripts.
Called “small” because they are usually only about 21-24 nucleotides long.
Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered).
Silence an mRNA by base pairing with some sequence on the mRNA.
Discovery of siRNA?
The first small RNA:
In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the
development of the worm C. elegans.
Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14.
Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions.
Types of RNAi ( non coding RNA)
MiRNA
Length (23-25 nt)
Trans acting
Binds with target MRNA in mismatch
Translation inhibition
Si RNA
Length 21 nt.
Cis acting
Bind with target Mrna in perfect complementary sequence
Piwi-RNA
Length ; 25 to 36 nt.
Expressed in Germ Cells
Regulates trnasposomes activity
MECHANISM OF RNAI:
First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces.
Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands.
The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it.
THE RISC COMPLEX:
RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA
Unwinding of double stranded Si RNA by ATP independent Helicase
Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA.
DICER: endonuclease (RNase Family III)
Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC)
One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute
ARGONAUTE PROTEIN :
1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA
2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity.
MiRNA:
The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .
Richard's aventures in two entangled wonderlandsRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
This presentation explores a brief idea about the structural and functional attributes of nucleotides, the structure and function of genetic materials along with the impact of UV rays and pH upon them.
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
A brief information about the SCOP protein database used in bioinformatics.
The Structural Classification of Proteins (SCOP) database is a comprehensive and authoritative resource for the structural and evolutionary relationships of proteins. It provides a detailed and curated classification of protein structures, grouping them into families, superfamilies, and folds based on their structural and sequence similarities.
What is greenhouse gasses and how many gasses are there to affect the Earth.moosaasad1975
What are greenhouse gasses how they affect the earth and its environment what is the future of the environment and earth how the weather and the climate effects.
Seminar of U.V. Spectroscopy by SAMIR PANDASAMIR PANDA
Spectroscopy is a branch of science dealing the study of interaction of electromagnetic radiation with matter.
Ultraviolet-visible spectroscopy refers to absorption spectroscopy or reflect spectroscopy in the UV-VIS spectral region.
Ultraviolet-visible spectroscopy is an analytical method that can measure the amount of light received by the analyte.
Deep Behavioral Phenotyping in Systems Neuroscience for Functional Atlasing a...Ana Luísa Pinho
Functional Magnetic Resonance Imaging (fMRI) provides means to characterize brain activations in response to behavior. However, cognitive neuroscience has been limited to group-level effects referring to the performance of specific tasks. To obtain the functional profile of elementary cognitive mechanisms, the combination of brain responses to many tasks is required. Yet, to date, both structural atlases and parcellation-based activations do not fully account for cognitive function and still present several limitations. Further, they do not adapt overall to individual characteristics. In this talk, I will give an account of deep-behavioral phenotyping strategies, namely data-driven methods in large task-fMRI datasets, to optimize functional brain-data collection and improve inference of effects-of-interest related to mental processes. Key to this approach is the employment of fast multi-functional paradigms rich on features that can be well parametrized and, consequently, facilitate the creation of psycho-physiological constructs to be modelled with imaging data. Particular emphasis will be given to music stimuli when studying high-order cognitive mechanisms, due to their ecological nature and quality to enable complex behavior compounded by discrete entities. I will also discuss how deep-behavioral phenotyping and individualized models applied to neuroimaging data can better account for the subject-specific organization of domain-general cognitive systems in the human brain. Finally, the accumulation of functional brain signatures brings the possibility to clarify relationships among tasks and create a univocal link between brain systems and mental functions through: (1) the development of ontologies proposing an organization of cognitive processes; and (2) brain-network taxonomies describing functional specialization. To this end, tools to improve commensurability in cognitive science are necessary, such as public repositories, ontology-based platforms and automated meta-analysis tools. I will thus discuss some brain-atlasing resources currently under development, and their applicability in cognitive as well as clinical neuroscience.
THE IMPORTANCE OF MARTIAN ATMOSPHERE SAMPLE RETURN.Sérgio Sacani
The return of a sample of near-surface atmosphere from Mars would facilitate answers to several first-order science questions surrounding the formation and evolution of the planet. One of the important aspects of terrestrial planet formation in general is the role that primary atmospheres played in influencing the chemistry and structure of the planets and their antecedents. Studies of the martian atmosphere can be used to investigate the role of a primary atmosphere in its history. Atmosphere samples would also inform our understanding of the near-surface chemistry of the planet, and ultimately the prospects for life. High-precision isotopic analyses of constituent gases are needed to address these questions, requiring that the analyses are made on returned samples rather than in situ.
THE IMPORTANCE OF MARTIAN ATMOSPHERE SAMPLE RETURN.
General Mineral Nutrition of Livestock
1. Unit- I, Lecture- 7
Importance, of minerals in animal
health and production
Dr. Pankaj Kumar Singh
Department of Animal Nutrition
Bihar Animal Sciences University, Patna, India
e-mail: vetpank@gmail.com ; 7909079625
BIHAR ANIMAL SCIENCES UNIVERSITY
Bihar Veterinary College, Patna
Department of Animal Nutrition
2. • Inorganic component of diet
• Represented by total ash
• Perform essential functions & must be present in food
• In animal tissues and feeds, minerals are present in
varying amounts and concentrations.
• Total body mineral Ca (46%)
P (29%)
Mg, Na, K, Cl, S (25%)
micro minerals (3%)
Minerals
3. • Essential Minerals:
– Major/macro- 07
– Minor/Micro-15
• Major/macro:
– The seven minerals that are present in high
concentration (>70 mg/kg live weight) are termed
as major minerals.
– Calcium (Ca),Phosphorus (P), Magnesium (Mg),
Sodium (Na), Potassium (K), Chlorine (Cl), Sulphur
(S)
Minerals
4. • Trace elements or Micro minerals are those minerals that are present
in low concentration (<70 mg/kg live weight)
• but are physiologically equally important.
• The following fifteen trace elements are essential to fullfil
physiological functions in the body
Minerals
Iron (Fe) Chromium (Cr)
Copper (Cu) Fluorine (F)
Cobalt (Co) Tin (Su)
Manganese (Mg) Vanadium (V)
Zinc (Zn) Silicon (Si)
Iodine (I) Nickel (Ni)
Selenium (Se) Arsenic (As)
Molybdenum (Mo)
5. I. Structural: form structural components of body organs and
tissues,
eg. as calcium, phosphorus and magnesium in bones
and teeth; and phosphorus and sulfur in muscle proteins.
II. Physiological: in body fluids and tissues as electrolytes
concerned with the maintenance of osmotic pressure, acid–base
balance, membrane permeability and transmission of nerve
impulses.
eg. sodium, potassium, chlorine, calcium and magnesium in
the blood, cerebrospinal fluid and gastric juice
III. Catalytic: act as catalysts in enzyme and endocrine systems, as
integral and specific components of the structure of metallo
enzymes and hormones or as activators (coenzymes) within
those systems.
Minerals: General functions
7. • Regulatory: minerals regulate cell replication and
differentiation;
– eg. calcium ions influence signal transduction and selenocysteine
influences gene transcription, The pivotal metabolic role of thyroxine has
been attributed to the influence of triiodothyronine on gene
transcription
• Component of biomolecules: of biologically important
compounds
– Iron in haemoglobin
– Cobalt in vitamin B12
– Iodine in the hormone thyroxine
Minerals: General functions
8. Dietary sources of Mineral
–Concentrate feed and forages
–Mineral supplements such as bone meal, mineral
mixture, common salt, calcite, shell grit etc.,
–Drinking water – minor source
–Soil contamination of herbage source for grazing
animals.
9. • Mineral req. are more difficult to define (w.r.t. organic nutrients) due
to involvement of so many factors.
• Strong interrelationship/ interaction among minerals causes
increased or decreased utilization.
• Presence of antimetal compounds in food
E.g. oxalates, phytates etc.
• Actual amount of mineral in diet affect utilization.
Higher concentration reduced absorption efficiency
• Mineral status of animal.
Iron deficient animal will have better efficient absorption than that
with higher iron reserve
• Form of mineral: salt (generally sulphates are more available than
oxides)
• Animal factors: Age, sex, productivity level, genetic make up
Factors affecting mineral req./ utilization
10. • Second most abundant nutrient element (after N) in body.
Functions of Ca
• Structural component of body (Skeleton and teeth): 99% of the
calcium in the body is present in the bones and teeth.
• controls the excitability of nerves and muscles
• required for normal clotting of blood
Functions of P
• occurs in close association with calcium in bone.
• vital role in energy metabolism (ATP)
• key role in metabolic reaction of carbohydrate, protein and lipids
(phosphorylated intermediate compounds).
• component of phospholipids, which are important in lipid transport
and metabolism as constituent of cell membranes.
• constituent of RNA and DNA.
• component of many enzyme systems.
Calcium & Phosphorus
11. Ca & P in bones:
• Total mineral in animal body 3%
• Out of total mineral 70% Ca & P
• Majority of Ca (99%) and P (80%) in bones (store of Ca & P) and teeth.
• In bones exist in ratio of 2: 1
• Moisture and fat free bone= 36% Ca and 17% P
Adult bone
Water 45%
Ash (minerals) 25%
Protein 20%
Fat 10%
Calcium & Phosphorus
12.
13. • Blood cells are devoid of Ca
• Plasma Ca in two forms: soluble ionised form (60% of total) and
bound with proteins (albumin and plasma protein)
• Blood Ca9-11 mg/dl
• Whole blood P 35-45 mg/dl (most of it present in cells
• Plasma iP 4-9mg/dl
• Blood concentration of P is more dependent on dietary manipulation
as compared to that of Ca.?????
Calcium & Phosphorus
14. Regulation of calcium metabolism
• Whenever blood calcium level decreases below the normal,
parathyroid gland is stimulated to secrete parathormone. This
hormone mobilizes calcium from the bone and also facilitates
reabsorption of calcium in the kidney.
• It also increases calcium absorption in the small intestine by
increasing the synthesis of 1,25 dihydroxy cholecalciferol (active form
of vitamin D) from 25 hydroxy cholecalciferol in the kidneys, which in
turn increases the synthesis of calcium binding protein resulting in
increased calcium absorption.
• High level of blood calcium stimulates the secretion of calcitonin,
which has antagonistic action to that of parathormone.
Calcium