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FEMALE REPRODUCTIVE ORGANS
Overview Ovary   Oviduct Uterus   Vagina Breast Components Functions  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Components Functions  Overview Ovary   Oviduct Uterus   Vagina Breast ,[object Object],[object Object],[object Object]
Overview Ovary   Oviduct Uterus   Vagina Breast Structure Oogenesis   Ovarian follicles Ovulation Corpus luteum  &  interstitial cells ,[object Object],[object Object]
Overview Ovary   Oviduct Uterus   Vagina Breast Structure Oogenesis   Ovarian follicles Ovulation Corpus luteum  &  interstitial cells ,[object Object],[object Object],[object Object]
Overview Ovary   Oviduct Uterus   Vagina Breast Structure Oogenesis   Ovarian follicles Ovulation Corpus luteum  &  interstitial cells
Overview Ovary   Oviduct Uterus   Vagina Breast Structure Oogenesis  Ovarian follicles Ovulation Corpus luteum  &  interstitial cells ,[object Object],[object Object],[object Object]
Overview Ovary   Oviduct Uterus   Vagina Breast Structure Oogenesis   Ovarian follicles Ovulation Corpus luteum  &  interstitial cells ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Overview Ovary   Oviduct Uterus   Vagina Breast Structure Oogenesis   Ovarian follicles Ovulation Corpus luteum  &  interstitial cells ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Overview Ovary   Oviduct Uterus   Vagina Breast Structure Oogenesis   Ovarian follicles Ovulation Corpus luteum  &  interstitial cells ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Overview Ovary   Oviduct Uterus   Vagina Breast Structure Oogenesis   Ovarian follicles Ovulation Corpus luteum  &  interstitial cells Primary follicle Unilaminar Multilaminar (preantral) Single layer Stratified of follicular cuboidal epithelium Zona pellucida  ( a thick amorphous layer of    glycoprotein   covering the oocyte)
Overview Ovary   Oviduct Uterus   Vagina Breast Structure Oogenesis   Ovarian follicles Ovulation Corpus luteum  &  interstitial cells
Overview Ovary   Oviduct Uterus   Vagina Breast Structure Oogenesis   Ovarian follicles Ovulation Corpus luteum  &  interstitial cells ,[object Object],[object Object],[object Object]
Overview Ovary   Oviduct Uterus   Vagina Breast Structure Oogenesis   Ovarian follicles Ovulation Corpus luteum  &  interstitial cells ,[object Object],[object Object]
Overview Ovary   Oviduct Uterus   Vagina Breast Structure Oogenesis   Ovarian follicles Ovulation Corpus luteum  &  interstitial cells ,[object Object],[object Object]
Overview Ovary   Oviduct Uterus   Vagina Breast Structure Oogenesis   Ovarian follicles Ovulation Corpus luteum  &  interstitial cells Secondary follicle 5. A group of cells concentrate around the oocyte and form the  corona radiata
Overview Ovary   Oviduct Uterus   Vagina Breast Structure Oogenesis   Ovarian follicles Ovulation Corpus luteum  &  interstitial cells Secondary follicle Fibroblasts  of the stroma  differentiate  to form  theca folliculi  (TF) Theca  Theca Interna Externa Androste- Fibroblasts nedione   Aromatase  (GC) Estrogen
Overview Ovary   Oviduct Uterus   Vagina Breast Structure Oogenesis   Ovarian follicles Ovulation Corpus luteum  &  interstitial cells ,[object Object],[object Object],[object Object],[object Object]
Overview Ovary   Oviduct Uterus   Vagina Breast Structure Oogenesis   Ovarian follicles Ovulation Corpus luteum  &  interstitial cells ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Overview Ovary   Oviduct Uterus   Vagina Breast Structure Oogenesis   Ovarian follicles Ovulation Corpus luteum  &  interstitial cells LH surge Blood flow through ovary  Plasma protein leakage Edema Local release of  prostaglandins ,  histamine ,  vasopressin  and  collagenase Pressure  Collagen degradation of  of follicular tunica albuginea fluid Ischemia & death of cells Rupture of outer follicular wall and ovulation
Overview Ovary   Oviduct Uterus   Vagina Breast Structure Oogenesis   Ovarian follicles Ovulation Corpus luteum   &  interstitial cells ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Overview Ovary   Oviduct Uterus   Vagina Breast Structure Oogenesis   Ovarian follicles Ovulation Corpus luteum   &  interstitial cells ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Overview Ovary   Oviduct Uterus   Vagina Breast Structure Oogenesis   Ovarian follicles Ovulation Corpus luteum   &  interstitial cells ,[object Object],[object Object],[object Object]
Overview Ovary   Oviduct Uterus   Vagina Breast Structure Oogenesis   Ovarian follicles Ovulation Corpus luteum   &  interstitial cells ,[object Object],[object Object],[object Object],[object Object]
Overview Ovary   Oviduct Uterus   Vagina Breast Structure Oogenesis   Ovarian follicles Ovulation Corpus luteum   &  interstitial cells Pituitary hormones control most ovarian functions
Overview Ovary   Oviduct Uterus   Vagina Breast Structure Oogenesis   Ovarian follicles Ovulation Corpus luteum  &  interstitial cells ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Overview Ovary   Oviduct Uterus   Vagina Breast Structure Oogenesis   Ovarian follicles Ovulation Corpus luteum  &  interstitial cells Follicular atresia
Overview Ovary   Oviduct Uterus   Vagina Breast Parts  Structure Function  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Overview Ovary   Oviduct Uterus   Vagina Breast Parts   Structure Function  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Overview Ovary   Oviduct Uterus   Vagina Breast Parts   Structure Function
Overview Ovary   Oviduct Uterus   Vagina Breast Parts   Structure Function  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Overview Ovary   Oviduct Uterus   Vagina Breast Parts   Structure Function  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
BREAK
Overview Ovary   Oviduct Uterus   Vagina Breast Structure Myometrium Endometrium Cycle Proliferative phase Secretory phase Menstrual phase  Cervix  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Structure Myometrium Endometrium Cycle Proliferative phase Secretory phase Menstrual phase  Cervix  Overview Ovary   Oviduct Uterus   Vagina Breast ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Structure Myometrium Endometrium Cycle Proliferative phase Secretory phase Menstrual phase  Cervix  Overview Ovary   Oviduct Uterus   Vagina Breast ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Structure Myometrium Endometrium Cycle Proliferative phase Secretory phase Menstrual phase  Cervix  Overview Ovary   Oviduct Uterus   Vagina Breast ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Structure Myometrium Endometrium Cycle Proliferative phase Secretory phase Menstrual phase  Cervix  Overview Ovary   Oviduct Uterus   Vagina Breast ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Structure Myometrium Endometrium Cycle Proliferative phase Secretory phase Menstrual phase  Cervix  Overview Ovary   Oviduct Uterus   Vagina Breast ,[object Object],[object Object],[object Object],[object Object],[object Object]
Structure Myometrium Endometrium Cycle Proliferative phase Secretory phase Menstrual phase  Cervix  Overview Ovary   Oviduct Uterus   Vagina Breast ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Structure Myometrium Endometrium Cycle Proliferative phase Secretory phase Menstrual phase  Cervix  Overview Ovary   Oviduct Uterus   Vagina Breast ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Structure Myometrium Endometrium Cycle Proliferative phase Secretory phase Menstrual phase  Cervix  Overview Ovary   Oviduct Uterus   Vagina Breast ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Structure Myometrium Endometrium Cycle Proliferative phase Secretory phase Menstrual phase  Cervix  Overview Ovary   Oviduct Uterus   Vagina Breast ,[object Object],[object Object],[object Object],[object Object],[object Object]
Structure Myometrium Endometrium Cycle Proliferative phase Secretory phase Menstrual phase   Cervix  Overview Ovary   Oviduct Uterus   Vagina Breast In absence of pregnancy,  CL ceases to function 10-12 days after ovulation Levels of  progesterone and estrogen in blood falls  rapidly Several cycles of  contraction of spiral arteries , closing off blood flow Ischemic necrosis  of vessel walls and functionalis layer of endometrium Rupture of blood vessels  and bleeding Endometrium reduced to a thin layer
Structure Myometrium Endometrium Cycle Proliferative phase Secretory phase Menstrual phase  Cervix   Overview Ovary   Oviduct Uterus   Vagina Breast ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Overview Ovary   Oviduct Uterus   Vagina Breast Structure ,[object Object],[object Object],[object Object],[object Object],[object Object]
Overview Ovary   Oviduct Uterus   Vagina Breast Structure ,[object Object],[object Object],[object Object]
Overview Ovary   Oviduct Uterus   Vagina Breast Structure ,[object Object],[object Object],[object Object],[object Object],[object Object]
Overview Ovary   Oviduct Uterus   Vagina Breast Structure ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Overview Ovary   Oviduct Uterus   Vagina   Breast Structure Development Pregnancy & Lactation Post-lactational regression ,[object Object],[object Object],[object Object],[object Object]
Overview Ovary   Oviduct Uterus   Vagina   Breast Structure Development Pregnancy & Lactation Post-lactational regression Before puberty : lactiferous sinus and lactiferous ducts In girls  during puberty  – breasts enlarge –  accumulation of adipose tissue and connective tissue , increased  growth and branching of lactiferous ducts  (estrogenic)
Overview Ovary   Oviduct Uterus   Vagina   Breast Structure Development Pregnancy & Lactation Post-lactational regression Adult women  –  lobes develop at the tips of the smallest ducts  embedded in loose connective tissue A lobe consists of  several ducts that empty into one terminal duct
Overview Ovary   Oviduct Uterus   Vagina   Breast Structure Development Pregnancy & Lactation Post-lactational regression Near the opening of nipple, the  lactiferous ducts dilate to form lactiferous sinuses   lined by stratified squamous epithelium at their external openings that changes to stratified columnar or cuboidal proximally . Lining of  lactiferous ducts and terminal ducts is formed of simple cuboidal epithelium  with closely packed  myoepithelial cells .
Overview Ovary   Oviduct Uterus   Vagina   Breast Structure Development Pregnancy & Lactation Post-lactational regression Connective tissue surrounding alveoli contains many  lymphocytes and plasma cells  (increase at end of pregnancy –  secrete IgA ) Nipple  – externally covered by  keratinized stratified squamous epithelium Abundant sensory nerve endings Areola  – skin around  the nipple –  darkens during  pregnancy
Overview Ovary   Oviduct Uterus   Vagina   Breast Structure Development Pregnancy & Lactation Post-lactational regression ,[object Object],[object Object],[object Object],[object Object],[object Object]
Overview Ovary   Oviduct Uterus   Vagina   Breast Structure Development Pregnancy & Lactation Post-lactational regression ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Overview Ovary   Oviduct Uterus   Vagina   Breast Structure Development Pregnancy & Lactation Post-lactational regression Weaning  (cessation of breast-feeding) Alveoli undergo degeneration through apoptosis Sloughing of whole cells Autophagy of cellular components Dead cells and debris removed by macrophages
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Female reproductive systems

  • 2.
  • 3.
  • 4.
  • 5.
  • 6. Overview Ovary Oviduct Uterus Vagina Breast Structure Oogenesis Ovarian follicles Ovulation Corpus luteum & interstitial cells
  • 7.
  • 8.
  • 9.
  • 10.
  • 11. Overview Ovary Oviduct Uterus Vagina Breast Structure Oogenesis Ovarian follicles Ovulation Corpus luteum & interstitial cells Primary follicle Unilaminar Multilaminar (preantral) Single layer Stratified of follicular cuboidal epithelium Zona pellucida ( a thick amorphous layer of glycoprotein covering the oocyte)
  • 12. Overview Ovary Oviduct Uterus Vagina Breast Structure Oogenesis Ovarian follicles Ovulation Corpus luteum & interstitial cells
  • 13.
  • 14.
  • 15.
  • 16. Overview Ovary Oviduct Uterus Vagina Breast Structure Oogenesis Ovarian follicles Ovulation Corpus luteum & interstitial cells Secondary follicle 5. A group of cells concentrate around the oocyte and form the corona radiata
  • 17. Overview Ovary Oviduct Uterus Vagina Breast Structure Oogenesis Ovarian follicles Ovulation Corpus luteum & interstitial cells Secondary follicle Fibroblasts of the stroma differentiate to form theca folliculi (TF) Theca Theca Interna Externa Androste- Fibroblasts nedione Aromatase (GC) Estrogen
  • 18.
  • 19.
  • 20. Overview Ovary Oviduct Uterus Vagina Breast Structure Oogenesis Ovarian follicles Ovulation Corpus luteum & interstitial cells LH surge Blood flow through ovary Plasma protein leakage Edema Local release of prostaglandins , histamine , vasopressin and collagenase Pressure Collagen degradation of of follicular tunica albuginea fluid Ischemia & death of cells Rupture of outer follicular wall and ovulation
  • 21.
  • 22.
  • 23.
  • 24.
  • 25. Overview Ovary Oviduct Uterus Vagina Breast Structure Oogenesis Ovarian follicles Ovulation Corpus luteum & interstitial cells Pituitary hormones control most ovarian functions
  • 26.
  • 27. Overview Ovary Oviduct Uterus Vagina Breast Structure Oogenesis Ovarian follicles Ovulation Corpus luteum & interstitial cells Follicular atresia
  • 28.
  • 29.
  • 30. Overview Ovary Oviduct Uterus Vagina Breast Parts Structure Function
  • 31.
  • 32.
  • 33. BREAK
  • 34.
  • 35.
  • 36.
  • 37.
  • 38.
  • 39.
  • 40.
  • 41.
  • 42.
  • 43.
  • 44. Structure Myometrium Endometrium Cycle Proliferative phase Secretory phase Menstrual phase Cervix Overview Ovary Oviduct Uterus Vagina Breast In absence of pregnancy, CL ceases to function 10-12 days after ovulation Levels of progesterone and estrogen in blood falls rapidly Several cycles of contraction of spiral arteries , closing off blood flow Ischemic necrosis of vessel walls and functionalis layer of endometrium Rupture of blood vessels and bleeding Endometrium reduced to a thin layer
  • 45.
  • 46.
  • 47.
  • 48.
  • 49.
  • 50.
  • 51. Overview Ovary Oviduct Uterus Vagina Breast Structure Development Pregnancy & Lactation Post-lactational regression Before puberty : lactiferous sinus and lactiferous ducts In girls during puberty – breasts enlarge – accumulation of adipose tissue and connective tissue , increased growth and branching of lactiferous ducts (estrogenic)
  • 52. Overview Ovary Oviduct Uterus Vagina Breast Structure Development Pregnancy & Lactation Post-lactational regression Adult women – lobes develop at the tips of the smallest ducts embedded in loose connective tissue A lobe consists of several ducts that empty into one terminal duct
  • 53. Overview Ovary Oviduct Uterus Vagina Breast Structure Development Pregnancy & Lactation Post-lactational regression Near the opening of nipple, the lactiferous ducts dilate to form lactiferous sinuses lined by stratified squamous epithelium at their external openings that changes to stratified columnar or cuboidal proximally . Lining of lactiferous ducts and terminal ducts is formed of simple cuboidal epithelium with closely packed myoepithelial cells .
  • 54. Overview Ovary Oviduct Uterus Vagina Breast Structure Development Pregnancy & Lactation Post-lactational regression Connective tissue surrounding alveoli contains many lymphocytes and plasma cells (increase at end of pregnancy – secrete IgA ) Nipple – externally covered by keratinized stratified squamous epithelium Abundant sensory nerve endings Areola – skin around the nipple – darkens during pregnancy
  • 55.
  • 56.
  • 57. Overview Ovary Oviduct Uterus Vagina Breast Structure Development Pregnancy & Lactation Post-lactational regression Weaning (cessation of breast-feeding) Alveoli undergo degeneration through apoptosis Sloughing of whole cells Autophagy of cellular components Dead cells and debris removed by macrophages