Bioinformatics is a fast-growing field of study that is providing major solutions to global challenges. It has its applications in the fields of medicine, pharmacology, agriculture, evolution, and environmental management. This document discusses one of the key tools in the field of Bioinformatics - the FastA Homology search algorithm. This document is for academic purposes and does not attempt to exhaust the subject. However, if you would like to discuss the subject in more depth, write to me on my email and we will surely have a discussion. Enjoy the read!
MediaEval 2015 - The SPL-IT-UC Query by Example Search on Speech system for M...multimediaeval
This document describes the system built by the SPL-IT-UC team from the Signal Processing Lab of Instituto de Telecomunicações (pole of Coimbra) and University of Coimbra for the Query by Example Search on Speech Task (QUESST) of MediaEval 2015. The submitted system filters considerable background noise by applying spectral subtraction, uses five phonetic recognizers from which posterior probabilities are extracted as features, implements novel modifications of Dynamic Time Warping (DTW) that focus on complex queries, and uses linear calibration and fusion to optimize results. This year’s task proved extra challenging in terms of acoustic conditions and match cases, though we observe the best results when merging all complex approaches.
http://ceur-ws.org/Vol-1436/
http://www.multimediaeval.org
Experimental Evaluation of a Novel Fast Beamsteering Algorithm for Link Re-Es...Avishek Patra
The millimeter-wave (mm-wave) bands are currently being explored for multi-Gbps wireless local area networks (WLANs). Directional antennas are required to overcome the high attenuation inherent at the mm-wave frequencies. However, directionality makes link maintenance and establishment tasks complex, especially under node mobility, as slight misalignment of antenna beams between nodes leads to link disruption. Consequently, low latency beamsteering algorithms are needed for fast link re-establishment to support seamless data provisioning. Solutions based on exhaustive sequential scanning induce high latency, thereby disrupting communication. On the other hand, existing low latency proposals typically consider only static links, depend on additional hardware, or require a priori information about the network environment. In this paper, we propose a generic, fast mm-wave beamsteering algorithm that utilizes the previous valid link information to initiate the feasible antenna sector pair search and adaptively increases the sector search space around it to re-establish a link. Additionally, we experimentally evaluate the performance of our algorithm through measurements conducted in a real indoor environment using 60 GHz packet radio transceivers. The results show that, compared to exhaustive sequential scanning, our algorithm reduces the required sector search space, and thereby the link re-establishment latency, by 89% on average compared to exhaustive sequential scanning.
With the constant increase of availability of processing power comes the need for longer passwords and hence the need for usage of passphrases in order to remember them. But are passphrases really safe? This session will explain how to crack passphrases up to 20 characters long, where normal password attacks most often fail, in a reasonable timespan using a normal gaming PC and a Markov process.
(Source: RSA USA 2016-San Francisco)
Bioinformatics is a fast-growing field of study that is providing major solutions to global challenges. It has its applications in the fields of medicine, pharmacology, agriculture, evolution, and environmental management. This document discusses one of the key tools in the field of Bioinformatics - the FastA Homology search algorithm. This document is for academic purposes and does not attempt to exhaust the subject. However, if you would like to discuss the subject in more depth, write to me on my email and we will surely have a discussion. Enjoy the read!
MediaEval 2015 - The SPL-IT-UC Query by Example Search on Speech system for M...multimediaeval
This document describes the system built by the SPL-IT-UC team from the Signal Processing Lab of Instituto de Telecomunicações (pole of Coimbra) and University of Coimbra for the Query by Example Search on Speech Task (QUESST) of MediaEval 2015. The submitted system filters considerable background noise by applying spectral subtraction, uses five phonetic recognizers from which posterior probabilities are extracted as features, implements novel modifications of Dynamic Time Warping (DTW) that focus on complex queries, and uses linear calibration and fusion to optimize results. This year’s task proved extra challenging in terms of acoustic conditions and match cases, though we observe the best results when merging all complex approaches.
http://ceur-ws.org/Vol-1436/
http://www.multimediaeval.org
Experimental Evaluation of a Novel Fast Beamsteering Algorithm for Link Re-Es...Avishek Patra
The millimeter-wave (mm-wave) bands are currently being explored for multi-Gbps wireless local area networks (WLANs). Directional antennas are required to overcome the high attenuation inherent at the mm-wave frequencies. However, directionality makes link maintenance and establishment tasks complex, especially under node mobility, as slight misalignment of antenna beams between nodes leads to link disruption. Consequently, low latency beamsteering algorithms are needed for fast link re-establishment to support seamless data provisioning. Solutions based on exhaustive sequential scanning induce high latency, thereby disrupting communication. On the other hand, existing low latency proposals typically consider only static links, depend on additional hardware, or require a priori information about the network environment. In this paper, we propose a generic, fast mm-wave beamsteering algorithm that utilizes the previous valid link information to initiate the feasible antenna sector pair search and adaptively increases the sector search space around it to re-establish a link. Additionally, we experimentally evaluate the performance of our algorithm through measurements conducted in a real indoor environment using 60 GHz packet radio transceivers. The results show that, compared to exhaustive sequential scanning, our algorithm reduces the required sector search space, and thereby the link re-establishment latency, by 89% on average compared to exhaustive sequential scanning.
With the constant increase of availability of processing power comes the need for longer passwords and hence the need for usage of passphrases in order to remember them. But are passphrases really safe? This session will explain how to crack passphrases up to 20 characters long, where normal password attacks most often fail, in a reasonable timespan using a normal gaming PC and a Markov process.
(Source: RSA USA 2016-San Francisco)
A brief information about the SCOP protein database used in bioinformatics.
The Structural Classification of Proteins (SCOP) database is a comprehensive and authoritative resource for the structural and evolutionary relationships of proteins. It provides a detailed and curated classification of protein structures, grouping them into families, superfamilies, and folds based on their structural and sequence similarities.
This pdf is about the Schizophrenia.
For more details visit on YouTube; @SELF-EXPLANATORY;
https://www.youtube.com/channel/UCAiarMZDNhe1A3Rnpr_WkzA/videos
Thanks...!
THE IMPORTANCE OF MARTIAN ATMOSPHERE SAMPLE RETURN.Sérgio Sacani
The return of a sample of near-surface atmosphere from Mars would facilitate answers to several first-order science questions surrounding the formation and evolution of the planet. One of the important aspects of terrestrial planet formation in general is the role that primary atmospheres played in influencing the chemistry and structure of the planets and their antecedents. Studies of the martian atmosphere can be used to investigate the role of a primary atmosphere in its history. Atmosphere samples would also inform our understanding of the near-surface chemistry of the planet, and ultimately the prospects for life. High-precision isotopic analyses of constituent gases are needed to address these questions, requiring that the analyses are made on returned samples rather than in situ.
Deep Behavioral Phenotyping in Systems Neuroscience for Functional Atlasing a...Ana Luísa Pinho
Functional Magnetic Resonance Imaging (fMRI) provides means to characterize brain activations in response to behavior. However, cognitive neuroscience has been limited to group-level effects referring to the performance of specific tasks. To obtain the functional profile of elementary cognitive mechanisms, the combination of brain responses to many tasks is required. Yet, to date, both structural atlases and parcellation-based activations do not fully account for cognitive function and still present several limitations. Further, they do not adapt overall to individual characteristics. In this talk, I will give an account of deep-behavioral phenotyping strategies, namely data-driven methods in large task-fMRI datasets, to optimize functional brain-data collection and improve inference of effects-of-interest related to mental processes. Key to this approach is the employment of fast multi-functional paradigms rich on features that can be well parametrized and, consequently, facilitate the creation of psycho-physiological constructs to be modelled with imaging data. Particular emphasis will be given to music stimuli when studying high-order cognitive mechanisms, due to their ecological nature and quality to enable complex behavior compounded by discrete entities. I will also discuss how deep-behavioral phenotyping and individualized models applied to neuroimaging data can better account for the subject-specific organization of domain-general cognitive systems in the human brain. Finally, the accumulation of functional brain signatures brings the possibility to clarify relationships among tasks and create a univocal link between brain systems and mental functions through: (1) the development of ontologies proposing an organization of cognitive processes; and (2) brain-network taxonomies describing functional specialization. To this end, tools to improve commensurability in cognitive science are necessary, such as public repositories, ontology-based platforms and automated meta-analysis tools. I will thus discuss some brain-atlasing resources currently under development, and their applicability in cognitive as well as clinical neuroscience.
Professional air quality monitoring systems provide immediate, on-site data for analysis, compliance, and decision-making.
Monitor common gases, weather parameters, particulates.
Observation of Io’s Resurfacing via Plume Deposition Using Ground-based Adapt...Sérgio Sacani
Since volcanic activity was first discovered on Io from Voyager images in 1979, changes
on Io’s surface have been monitored from both spacecraft and ground-based telescopes.
Here, we present the highest spatial resolution images of Io ever obtained from a groundbased telescope. These images, acquired by the SHARK-VIS instrument on the Large
Binocular Telescope, show evidence of a major resurfacing event on Io’s trailing hemisphere. When compared to the most recent spacecraft images, the SHARK-VIS images
show that a plume deposit from a powerful eruption at Pillan Patera has covered part
of the long-lived Pele plume deposit. Although this type of resurfacing event may be common on Io, few have been detected due to the rarity of spacecraft visits and the previously low spatial resolution available from Earth-based telescopes. The SHARK-VIS instrument ushers in a new era of high resolution imaging of Io’s surface using adaptive
optics at visible wavelengths.
Comparing Evolved Extractive Text Summary Scores of Bidirectional Encoder Rep...University of Maribor
Slides from:
11th International Conference on Electrical, Electronics and Computer Engineering (IcETRAN), Niš, 3-6 June 2024
Track: Artificial Intelligence
https://www.etran.rs/2024/en/home-english/
What is greenhouse gasses and how many gasses are there to affect the Earth.moosaasad1975
What are greenhouse gasses how they affect the earth and its environment what is the future of the environment and earth how the weather and the climate effects.
Earliest Galaxies in the JADES Origins Field: Luminosity Function and Cosmic ...Sérgio Sacani
We characterize the earliest galaxy population in the JADES Origins Field (JOF), the deepest
imaging field observed with JWST. We make use of the ancillary Hubble optical images (5 filters
spanning 0.4−0.9µm) and novel JWST images with 14 filters spanning 0.8−5µm, including 7 mediumband filters, and reaching total exposure times of up to 46 hours per filter. We combine all our data
at > 2.3µm to construct an ultradeep image, reaching as deep as ≈ 31.4 AB mag in the stack and
30.3-31.0 AB mag (5σ, r = 0.1” circular aperture) in individual filters. We measure photometric
redshifts and use robust selection criteria to identify a sample of eight galaxy candidates at redshifts
z = 11.5 − 15. These objects show compact half-light radii of R1/2 ∼ 50 − 200pc, stellar masses of
M⋆ ∼ 107−108M⊙, and star-formation rates of SFR ∼ 0.1−1 M⊙ yr−1
. Our search finds no candidates
at 15 < z < 20, placing upper limits at these redshifts. We develop a forward modeling approach to
infer the properties of the evolving luminosity function without binning in redshift or luminosity that
marginalizes over the photometric redshift uncertainty of our candidate galaxies and incorporates the
impact of non-detections. We find a z = 12 luminosity function in good agreement with prior results,
and that the luminosity function normalization and UV luminosity density decline by a factor of ∼ 2.5
from z = 12 to z = 14. We discuss the possible implications of our results in the context of theoretical
models for evolution of the dark matter halo mass function.
2. Introduction
• The FASTA algorithm is a heuristic method for
string comparison.
• Developed by Lipman and Pearson in 1985
and further improved in 1988.
• It performs Local alignment of sequences
• It uses hash coding in which the sequence is
broken into small “words or K-tuples” of
specific sizes.
3. FASTA
• FASTA’s general strategy
– is to find the most significant diagonals in the dot-
plot or dynamic programming matrix.
– compute best diagonals from all frames of
alignment in a dot plot
2) Word method looks for exact matches
between words in query and test sequence
– hash tables (fast computer technique)
– DNA words are usually 6 bases
– protein words are 1 or 2 amino acids
– only searches for diagonals in region of word
matches = faster searching
4. Steps in FASTA Algorithm
Four steps:
1. Identify regions of similarity:
• Using the ktup parameter which specifies the size of
the word
• uses the word hits to identify potential matches
between the query sequence and database sequence
• Lesser the ktup value, more sensitive the search
• By default ktup is 2 for proteins and 4 or 6 for
nucleotides
• 10 best diagonal regions found based on #matches and
distance between matches
5. 2. Rescore regions and identify best initial
regions
• PAM250 or other scoring matrix used for
rescoring the 10 diagonal regions identified in
step 1 to allow for conservative replacements
and runs of identities shorter than ktup
• For each of the best diagonal regions, identify
“initial region” that is best scoring sub region
6. Makes Longest Diagonal
3) after all diagonals found, tries to join
diagonals by adding gaps
4) computes alignments in regions of best
diagonals
