The document discusses evidence-based practice (EBP) in nursing and healthcare. It defines EBP as integrating the best research evidence, clinical expertise, and patient values. The key figures in the development of EBP are Florence Nightingale, who emphasized using statistics to improve patient outcomes, and Archibald Cochrane, who advocated for using randomized controlled trials and research in patient care. The document also outlines the five steps of EBP: asking a focused question, finding evidence, appraising the evidence, applying evidence to practice, and evaluating outcomes. Several models of implementing EBP are described, including the Stetler, Iowa, and Johns Hopkins models. The goal of EBP is to make nursing practice more objective and