This document discusses evidence-based practice (EBP) in nursing. It provides background on EBP, noting that EBP integrates the best research evidence with clinical expertise and patient preferences. The document reviews the history of EBP and its importance for improving patient outcomes. It defines EBP in nursing as locating, appraising, and applying the best medical and nursing research evidence to improve clinical practice. The document also outlines models of EBP, barriers to implementing EBP, and strategies for overcoming those barriers.