Gillian Butcher1,Theresa Swanson2, Loreto Pinnuck1, Meagan Shannon3
1.Monash Health, Melbourne Australia
2.South West Healthcare, Warrnambool Australia 3.Peninsula Health, Melbourne Australia
The Efficacy of Pocket Elimination/Reduction Compared to Access Flap Surgery: A SystematicReview and Meta-analysis
To assess the efficacy and adverse effects of resective
surgery compared to access flap in patients with
periodontitis.
Impact of Different Surgical Protocols on Dimensional Changes of Free Soft Ti...Dr. B.V.Parvathy
To determine if there is a difference in the amount of shrinkage during
healing of free soft tissue autografts (FSTA) using different surgical
techniques—suturing the vestibular flap margin apically to the base of
the recipient bed versus leaving the flap margin free and unsutured.
The Efficacy of Pocket Elimination/Reduction Compared to Access Flap Surgery: A SystematicReview and Meta-analysis
To assess the efficacy and adverse effects of resective
surgery compared to access flap in patients with
periodontitis.
Impact of Different Surgical Protocols on Dimensional Changes of Free Soft Ti...Dr. B.V.Parvathy
To determine if there is a difference in the amount of shrinkage during
healing of free soft tissue autografts (FSTA) using different surgical
techniques—suturing the vestibular flap margin apically to the base of
the recipient bed versus leaving the flap margin free and unsutured.
Course Director, Elizabeth A. Stewart, MD, prepared useful Practice Aids pertaining to uterine fibroids and endometriosis for this CME activity titled "Advances in Medical Options for Uterine Fibroids and Endometriosis: Clinical Highlights From Montreal." For the full presentation, monograph, complete CME information, and to apply for credit, please visit us at http://bit.ly/2HY3HDz. CME credit will be available until June 24, 2020.
Current Role of Surgery in Endometriosis; Indications and ProgressCrimsonpublisherssmoaj
Endometriosis is a chronic debilitating disease , which affects women of reproductive age group, although medical therapy may be helpful in managing pain associated with Endometriosis or infertility, surgery becomes an integral part of managing this disease .Although initially surgery was limited to l aporotomy associated with ovarian cystectomy and/or TAH with BSO. Laporoscopy gradually replaced that. Though diagnostic laparoscopy is used for confirmation of endometriosis by histological examination, it is not acceptable that Laporoscopy be done in multiple steps, initially to diagnose and later for treatment. Recently a lot of advancement has come in the imaging techniques by which one can combine planning of surgery based on the imaging classification. Deep endometriosis involving bowel, genitourinary tract can be dealt by careful dissection in controlled trained hands, in a well equipped set up to achieve the optimum results .Endometriosis associated infertility may or may not warrant surgery as with multiple studies operation on ovarian endometriomas might land up in reducing ovarian reserve - while doing straight IVF may result in better pregnancy rates ,getting good oocyte retrieval in contrast to poor ovarian reserve resulting from damage to ovarian morphology. Use of laser for ovarian cystectomy helps in getting better outcomes than simple drainage and coagulation procedures. Robotic surgery is the latest addition, which aids in better dissection and management but its problem is its cost, not accessible to many patients and not many trained personnel available.
IOSR Journal of Dental and Medical Sciences is one of the speciality Journal in Dental Science and Medical Science published by International Organization of Scientific Research (IOSR). The Journal publishes papers of the highest scientific merit and widest possible scope work in all areas related to medical and dental science. The Journal welcome review articles, leading medical and clinical research articles, technical notes, case reports and others.
This is one of my recent presentations on ambulatory surgery in Minimal Access or Laparoscopy GI Surgery. How to plan and ambulate and discharge patients early. My Personal experience.
In working within the parameters of the SaferHealth Care Now bundle what have we within Sunrise been able to do to increase patients safety. By looking at indicators of infection we have been able to set up improvement projects to work towards a goal of zero clean surgical site infections. This session is to describe three of these improvement projects.
Course Director, Elizabeth A. Stewart, MD, prepared useful Practice Aids pertaining to uterine fibroids and endometriosis for this CME activity titled "Advances in Medical Options for Uterine Fibroids and Endometriosis: Clinical Highlights From Montreal." For the full presentation, monograph, complete CME information, and to apply for credit, please visit us at http://bit.ly/2HY3HDz. CME credit will be available until June 24, 2020.
Current Role of Surgery in Endometriosis; Indications and ProgressCrimsonpublisherssmoaj
Endometriosis is a chronic debilitating disease , which affects women of reproductive age group, although medical therapy may be helpful in managing pain associated with Endometriosis or infertility, surgery becomes an integral part of managing this disease .Although initially surgery was limited to l aporotomy associated with ovarian cystectomy and/or TAH with BSO. Laporoscopy gradually replaced that. Though diagnostic laparoscopy is used for confirmation of endometriosis by histological examination, it is not acceptable that Laporoscopy be done in multiple steps, initially to diagnose and later for treatment. Recently a lot of advancement has come in the imaging techniques by which one can combine planning of surgery based on the imaging classification. Deep endometriosis involving bowel, genitourinary tract can be dealt by careful dissection in controlled trained hands, in a well equipped set up to achieve the optimum results .Endometriosis associated infertility may or may not warrant surgery as with multiple studies operation on ovarian endometriomas might land up in reducing ovarian reserve - while doing straight IVF may result in better pregnancy rates ,getting good oocyte retrieval in contrast to poor ovarian reserve resulting from damage to ovarian morphology. Use of laser for ovarian cystectomy helps in getting better outcomes than simple drainage and coagulation procedures. Robotic surgery is the latest addition, which aids in better dissection and management but its problem is its cost, not accessible to many patients and not many trained personnel available.
IOSR Journal of Dental and Medical Sciences is one of the speciality Journal in Dental Science and Medical Science published by International Organization of Scientific Research (IOSR). The Journal publishes papers of the highest scientific merit and widest possible scope work in all areas related to medical and dental science. The Journal welcome review articles, leading medical and clinical research articles, technical notes, case reports and others.
This is one of my recent presentations on ambulatory surgery in Minimal Access or Laparoscopy GI Surgery. How to plan and ambulate and discharge patients early. My Personal experience.
In working within the parameters of the SaferHealth Care Now bundle what have we within Sunrise been able to do to increase patients safety. By looking at indicators of infection we have been able to set up improvement projects to work towards a goal of zero clean surgical site infections. This session is to describe three of these improvement projects.
MicroGuide app, pop up uni, 1pm, 3 september 2015NHS England
Expo is the most significant annual health and social care event in the calendar, uniting more NHS and care leaders, commissioners, clinicians, voluntary sector partners, innovators and media than any other health and care event.
Expo 15 returned to Manchester and was hosted once again by NHS England. Around 5000 people a day from health and care, the voluntary sector, local government, and industry joined together at Manchester Central Convention Centre for two packed days of speakers, workshops, exhibitions and professional development.
This year, Expo was more relevant and engaging than ever before, happening within the first 100 days of the new Government, and almost 12 months after the publication of the NHS Five Year Forward View. It was also a great opportunity to check on and learn from the progress of Greater Manchester as the area prepares to take over a £6 billion devolved health and social care budget, pledging to integrate hospital, community, primary and social care and vastly improve health and well-being.
More information is available online: www.expo.nhs.uk
This presentation was done by RUTAYISIRE François Xavier and ISHIMWE Diane, medical students at University of RWANDA School of Medicine and pharmacy, department of medicine and surgery. They did it while they were in Year 4 (Doctorate2), under supervision of Dr Ntakiyiruta Georges,Mmed,FCSECSA. It tell us about what a surgical safety checklist is, and why is it important in surgical field.
This presentation was prepared by RUTAYISIRE François Xavier and ISHIMWE Diane, Medical students in Year 4(Doctorate 2) at University of RWANDA school of medicine and Pharmacy, Department of Medicine and Surgery. we did the work under supervision of Dr Ntakiyiruta Georges,Mmed,FCSECSA
ICN Victoria presents Dr Dashiell Gantner, research fellow at the Monash University in Melbourne. Here he talks about translating ICU research into clinical practice.
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...Oleg Kshivets
Overall life span (LS) was 1671.7±1721.6 days and cumulative 5YS reached 62.4%, 10 years – 50.4%, 20 years – 44.6%. 94 LCP lived more than 5 years without cancer (LS=2958.6±1723.6 days), 22 – more than 10 years (LS=5571±1841.8 days). 67 LCP died because of LC (LS=471.9±344 days). AT significantly improved 5YS (68% vs. 53.7%) (P=0.028 by log-rank test). Cox modeling displayed that 5YS of LCP significantly depended on: N0-N12, T3-4, blood cell circuit, cell ratio factors (ratio between cancer cells-CC and blood cells subpopulations), LC cell dynamics, recalcification time, heparin tolerance, prothrombin index, protein, AT, procedure type (P=0.000-0.031). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and N0-12 (rank=1), thrombocytes/CC (rank=2), segmented neutrophils/CC (3), eosinophils/CC (4), erythrocytes/CC (5), healthy cells/CC (6), lymphocytes/CC (7), stick neutrophils/CC (8), leucocytes/CC (9), monocytes/CC (10). Correct prediction of 5YS was 100% by neural networks computing (error=0.000; area under ROC curve=1.0).
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
These lecture slides, by Dr Sidra Arshad, offer a quick overview of the physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar lead (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
6. Describe the flow of current around the heart during the cardiac cycle
7. Discuss the placement and polarity of the leads of electrocardiograph
8. Describe the normal electrocardiograms recorded from the limb leads and explain the physiological basis of the different records that are obtained
9. Define mean electrical vector (axis) of the heart and give the normal range
10. Define the mean QRS vector
11. Describe the axes of leads (hexagonal reference system)
12. Comprehend the vectorial analysis of the normal ECG
13. Determine the mean electrical axis of the ventricular QRS and appreciate the mean axis deviation
14. Explain the concepts of current of injury, J point, and their significance
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. Chapter 3, Cardiology Explained, https://www.ncbi.nlm.nih.gov/books/NBK2214/
7. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Adv. biopharm. APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMSAkankshaAshtankar
MIP 201T & MPH 202T
ADVANCED BIOPHARMACEUTICS & PHARMACOKINETICS : UNIT 5
APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMS By - AKANKSHA ASHTANKAR
The Gram stain is a fundamental technique in microbiology used to classify bacteria based on their cell wall structure. It provides a quick and simple method to distinguish between Gram-positive and Gram-negative bacteria, which have different susceptibilities to antibiotics
Best Ayurvedic medicine for Gas and IndigestionSwastikAyurveda
Here is the updated list of Top Best Ayurvedic medicine for Gas and Indigestion and those are Gas-O-Go Syp for Dyspepsia | Lavizyme Syrup for Acidity | Yumzyme Hepatoprotective Capsules etc
Muktapishti is a traditional Ayurvedic preparation made from Shoditha Mukta (Purified Pearl), is believed to help regulate thyroid function and reduce symptoms of hyperthyroidism due to its cooling and balancing properties. Clinical evidence on its efficacy remains limited, necessitating further research to validate its therapeutic benefits.
Role of Mukta Pishti in the Management of Hyperthyroidism
EWMA 2013-Ep446-ULTRASONIC ASSISTED WOUND DEBRIDEMENT – AN AUSTRALIAN EXPERIENCE
1. Email: gillian.butcher@southernhealth.org.au
Ultrasonic Assisted Wound Debridement: An
Australian Experience
Gillian Butcher1,Theresa Swanson2, Loreto Pinnuck1, Meagan Shannon3
1.Monash Health, Melbourne Australia
2.South West Healthcare, Warrnambool Australia 3.Peninsula Health, Melbourne Australia
MonashHealth
2. Background and Aim
• 4 public hospitals' in Victoria
Australia
• Funded by Department of
Health New Technology
program
• The aim of trial was to
implement Ultrasonic Assisted
Wound Debridement (UAWD),
into different clinical
environments with different
wound types
3. Method
• A central minimum data set
(CMDS)
• Policies, procedures and
patient education material
• Quarterly meetings of all sites
with the Dept of Health to
review cost, issues and activity
• A train-the-trainer model to
ensure the ongoing availability
of suitably trained staff.
This trial focussed on four types
of wounds:
• Diabetic Foot ulcers
• Chronic leg ulcers
• Pressure ulcers/injuries
• Dehisced surgical wounds
4. Results :
29%
47%
12%
12%
Types of wounds treated
DFUs
Chronic leg ulcers
Pressure injury/ulcer
Dihisced surgical
wounds
• The total number of treatments was 1056 on 223 patients:
• Average number of treatments per patient = 4.7
• 50% of wounds had greater than 75% of wound bed slough
removed with this therapy at each debridement
• While data is still being analysed for percentage of healing,
• one site has shown 60.32% reduction in size of leg ulcers
and
• 36% reduction in size of diabetic foot ulcers over the
course of treatment.
5. Clinical outcomes
Decreased hospital admissions due to:
• Effective debridement in an
outpatient setting and for patients
not suitable for theatre
• Improved, rapid and safe
debridement of wet slough
• Bioburden reduction and
antibacterial activity improved
• Decreased infection rates –
only one patient was admitted to
hospital for a wound infection
6. Clinical outcomes
Cost effectiveness:
• UAWD can be performed in an outpatient
or inpatient setting.
• The total cost of a UAWD treatment was
calculated at $180AUD (including staff
time and all consumables) compared with:
• Simple theatre debridement $3500 AUD
• Average inpatient bed day $800AUD
• One patient had 32 hospital admissions
from 2006-2010 for wound management.
After commencing on UAWD therapy in
January 2011 he had no admissions that
year due to weekly treatments
Ease of use:
• Training is simple and straightforward
and the train-the-trainer model ensures a
continuous skilled workforce.
• All staff trained found the Sonoca 185
easy to use
Pain:
• Not painless as suggested by the
literature
• Topical analgesic applied to the wound at
least 30 minutes prior to UAWD
• 7.9% of participants discontinued
treatment due to pain issues.
7. Case Studies:1, – Dehisced surgical wound and
decreased bioburden
Morbidly obese 60 year old female:
• Dehisced abdominal wound following bowel
surgery.
• UAWD performed at 60% amplitude for 30
minutes
• After one treatment this wound was ready
for Negative Pressure Wound Therapy
(NPWT)
• While the patient was on NWPT the wound
developed pseudomonas aeruginosa
• UAWD in contact mode was used
consecutively for 3 days. At this time
pathology testing showed the wound to be
pseudomonas free.
8. Case Study 2 – Non-healing donor site
Three months post-Coronary Artery Bypass
Graft this graft donor site had not healed
and was infected with Staphylococcus
Aureus:
• The base of the wound had 90% slough and
10% granulation tissue
• Systemic antibiotics were implemented
• LFUD was used in contact mode at 60%
amplitude for 20 minutes, followed by
moist wound dressings
• The following day the wound remained
slough free and Negative Pressure Wound
Therapy was applied
• The wound healed within 4 months.
• No theatre debridement was necessary
9. Conclusions:
• Safe and effective
• Selective debridement
• Antibacterial activity
• Wound stimulation effects
• Sustainable ongoing treatment
modality
Further investigations:
A randomized control trial currently
being conducted at Monash Health
comparing UAWD to conservative
sharps debridement will hopefully
provide us with a better comparison of
healing rates.
10. References
Butcher G, Pinnuck L. Wound Bed Preparation - ultrasonic-assisted
debridement. British Journal of Nursing, 2013 (Tissue Viability
Supplement), Vol 22, No 6
Shannon MK, Williams A & Bloomer M. Low-frequency ultrasound
debridement (Sonoca-185) in acute wound management: A case study.
Wound Practice & Research 2012 Vol 20 Issue 4
Michailidis L, Low Frequency Ultrasonic Debridement: A case of healing
against all odds. Connective Issues, Vol 15 Issue 1 2012