Sedimentation for determining molecular weight of macromoleculesShubhangiSuri1
Process of sedimentation with mechanism of action and mathematical derivations, different methods for separation of macromolecules by sedimentation, viscometry vs sedimentation
Quantitative estimation of carbohydrates Likhith KLIKHITHK1
Carbohydrates are one of the three macronutrients in the human diet, along with protein and fat. These molecules contain carbon, hydrogen, and oxygen atoms. Carbohydrates play an important role in the human body. They act as an energy source, help control blood glucose and insulin metabolism, participate in cholesterol and triglyceride metabolism, and help with fermentation. The digestive tract begins to break down carbohydrates into glucose, which is used for energy, upon consumption. Any extra glucose in the bloodstream is stored in the liver and muscle tissue until further energy is needed. Carbohydrates is an umbrella term that encompasses sugar, fruits, vegetables, fibers, and legumes. While there are numerous divisions of carbohydrates, the human diet benefits mostly from a certain subset.
Sedimentation for determining molecular weight of macromoleculesShubhangiSuri1
Process of sedimentation with mechanism of action and mathematical derivations, different methods for separation of macromolecules by sedimentation, viscometry vs sedimentation
Quantitative estimation of carbohydrates Likhith KLIKHITHK1
Carbohydrates are one of the three macronutrients in the human diet, along with protein and fat. These molecules contain carbon, hydrogen, and oxygen atoms. Carbohydrates play an important role in the human body. They act as an energy source, help control blood glucose and insulin metabolism, participate in cholesterol and triglyceride metabolism, and help with fermentation. The digestive tract begins to break down carbohydrates into glucose, which is used for energy, upon consumption. Any extra glucose in the bloodstream is stored in the liver and muscle tissue until further energy is needed. Carbohydrates is an umbrella term that encompasses sugar, fruits, vegetables, fibers, and legumes. While there are numerous divisions of carbohydrates, the human diet benefits mostly from a certain subset.
Gas chromatography-Mass spectrometry (GC-MS)Saira Fatima
PRESENTED BY
SAIRA FATIMA
SABAHAT MEHMOOD
SANA USMAN
MSc 4 (2018-2020)
Department of MicroBiology & Molecular Genetics
University of the Punjab
Lahore, Pakistan
Hi, I'm Presents a Research article for Journal club entitled with
"3D Printing: A Case of ZipDose® Technology –World’s First 3D Printing Platform to Obtain FDA Approval for a Pharmaceutical Product"
Reference (Source article):
1. West, Thomas & Bradbury, Thomas. (2018). 3D Printing: A Case of ZipDose® Technology - World's First 3D Printing Platform to Obtain FDA Approval for a Pharmaceutical Product: Process Engineering and Additive Manufacturing. https://doi.org/10.1002/9783527813704...
2. https://www.aprecia.com/technology/zipdose
Gas chromatography-Mass spectrometry (GC-MS)Saira Fatima
PRESENTED BY
SAIRA FATIMA
SABAHAT MEHMOOD
SANA USMAN
MSc 4 (2018-2020)
Department of MicroBiology & Molecular Genetics
University of the Punjab
Lahore, Pakistan
Hi, I'm Presents a Research article for Journal club entitled with
"3D Printing: A Case of ZipDose® Technology –World’s First 3D Printing Platform to Obtain FDA Approval for a Pharmaceutical Product"
Reference (Source article):
1. West, Thomas & Bradbury, Thomas. (2018). 3D Printing: A Case of ZipDose® Technology - World's First 3D Printing Platform to Obtain FDA Approval for a Pharmaceutical Product: Process Engineering and Additive Manufacturing. https://doi.org/10.1002/9783527813704...
2. https://www.aprecia.com/technology/zipdose
stability The ability of a pharmaceutical product to retain its chemical, physical, microbiological and biopharmaceutical properties within specified limits throughout its shelf-life.Why is stability of a drug important?
Drug stability affects the safety and efficacy of the drug product; degradation impurities may cause a loss of efficacy and generate possible adverse effects. Therefore, achieving the chemical and physical stability of drugs is essential to ensure their quality and safety.Common factors that affect this stability include temperature, light, pH, oxidation and enzymatic degradation. Special considerations are also required when dealing with chiral molecules, deuterated internal standards and large biomolecules.
Upcoming USP 665 - Level of Characterization of Single-Use Systems Today and ...Merck Life Sciences
Register for the interactive, on-demand webinar now: https://bit.ly/USP665
Single-use plastic systems are being utilized more frequently especially for COVID-19 vaccine manufacturing. However, there are issues regarding standardization of quality information that limits implementation efficiencies. One of the challenges is the evaluation of leachables derived from a variety of different plastic components in a timely manner.
Since the USP <665> highlights a risk assessment approach with no typical pass/fail limit, approaches to decision-making based on the extractables data package will be reviewed. In addition, we will highlight legacy testing requirements which may not be necessary once USP <665> is implemented.
In this webinar, we will discuss:
- Regulatory expectations of extractables and leachables assessment today and tomorrow
- The right criteria that need to be assessed to select the type and quality of plastic materials for use in biopharmaceutical manufacturing
Upcoming USP 665 - Level of Characterization of Single-Use Systems Today and ...MilliporeSigma
Register for the interactive, on-demand webinar now: https://bit.ly/USP665
Single-use plastic systems are being utilized more frequently especially for COVID-19 vaccine manufacturing. However, there are issues regarding standardization of quality information that limits implementation efficiencies. One of the challenges is the evaluation of leachables derived from a variety of different plastic components in a timely manner.
Since the USP <665> highlights a risk assessment approach with no typical pass/fail limit, approaches to decision-making based on the extractables data package will be reviewed. In addition, we will highlight legacy testing requirements which may not be necessary once USP <665> is implemented.
In this webinar, we will discuss:
- Regulatory expectations of extractables and leachables assessment today and tomorrow
- The right criteria that need to be assessed to select the type and quality of plastic materials for use in biopharmaceutical manufacturing
Challenges using Multiple Single-use Systems: Functionality versus Extractabl...MilliporeSigma
As single-use technologies continue to expand in pharmaceutical manufacturing processes, the risk assessment for extractables and leachables becomes increasingly complex. Join this webinar to obtain guidance on how to perform risk evaluation on a process with multiple single-use components.
A Single-Use System (SUS) is typically designed for a specific process step. In many cases, single-use components are chosen based on their functionality. The challenge arises when there are multiple processing steps-- as the different applications and product matrices are evaluated, the complexity of the risk assessment increases. Complexity includes component evaluation, process conditions, and model solvents streams which ultimately relates to the patient safety risk.
This webinar will evaluate the different single-use components with respect to compatibility and extractables and leachables. A case study will be used to demonstrate the complexity and potential concerns when performing a risk evaluation on the manufacturing process.
In this webinar, you will learn:
- Risk assessment of extractables
- Single-use component evaluation
- Complexity when evaluating multiple assemblies
Challenges using Multiple Single-use Systems: Functionality versus Extractabl...Merck Life Sciences
As single-use technologies continue to expand in pharmaceutical manufacturing processes, the risk assessment for extractables and leachables becomes increasingly complex. Join this webinar to obtain guidance on how to perform risk evaluation on a process with multiple single-use components.
A Single-Use System (SUS) is typically designed for a specific process step. In many cases, single-use components are chosen based on their functionality. The challenge arises when there are multiple processing steps-- as the different applications and product matrices are evaluated, the complexity of the risk assessment increases. Complexity includes component evaluation, process conditions, and model solvents streams which ultimately relates to the patient safety risk.
This webinar will evaluate the different single-use components with respect to compatibility and extractables and leachables. A case study will be used to demonstrate the complexity and potential concerns when performing a risk evaluation on the manufacturing process.
In this webinar, you will learn:
- Risk assessment of extractables
- Single-use component evaluation
- Complexity when evaluating multiple assemblies
Toy Safety – A Guide to the Latest Updates to ASTM F963QIMA
Safety regulations in the toy and children’s products industry are subject to frequent updates, to become more harmonized and reflect the latest new scientific data.
ASTM F963-11, the mandatory US standard for toy safety, has undergone significant revisions, with the new version, ASTM F963-16, due to become mandatory in April 2017. In our free webinar, we reviewed key updates to ASTM F963 to help you maintain compliance in your supply chain.
Why attend this webinar?
• Get a recap of ASTM F963 purpose and scope of application
• Learn about significant changes to Chemical, Microbiological, Physical, Electrical, Labeling, Instruction, and Producer Marking requirements
• Understand the purpose of changes from ASTM F963-11 to F963-16 and the steps you need to take to stay compliant
A little description of what the Cube can do for you:
20 colors and dual-color jetted mashables. Mix and match dual-color and dual-materials.
2X faster than other printers.
instant load cartridges
preloaded filament jets
auto-leveling print pad
Specs:
Print volume: 6 x 6 x 6“ / 152 x 152 x 152 mm
Material: PLA plastic and ABS plastic
Layer thickness: 70 microns, 200 microns in fast mode
The first 3D printer that prints a nylon-carbon fiber blend stronger-to-weight than aluminum 6061 and adopted by NASA! Only 5500 US$!
This specification sheet describes:
- Build size
- Technology
- Material
- Resolution
- Software compatibility
Applications and Technologies of Selective Laser Sintering. See what clearances, materials and other design or engineering considerations 3D Systems recommends. From baffles to tanks, know that you are not designing alone and we are here to help.
Strong, tough plastic that stands up to the rigors of long-term real world use replacing traditionally injection molded articles. Engineered for the ProX 500 SLS® 3D printer, with exceptional recyclability and unparalleled mechanical properties. Replace articles that are typically CNC machined or injection molded with this tough plastic.
An engineered composite with the durability of an
injection molded part and the appearance of cast
aluminum. Address broad applications requiring high stiffness and heat resistance. For aerodynamic wind-tunnel models, household appliances, consumer products, automotive manifolds, ducts, electrical clips, cases, etc.
DuraForm HST Composite - SLS Systems - Material properties (EN)Quoc Tuan Duong, ing.
High specific stiffness, elevated temperature resistance, anisotropic mechanical properties just like fiber-filled, injection
molded materials. For UAV structural components, housings, enclosures, impellers, connectors, consumer sporting goods applications, etc.
Durable polyamide (nylon) material for real-world physical
testing and functional use. Nicely balanced mechanical properties and processability. Good chemical resistance and low moisture absorption. Medical applications requiring
USP Class VI compliance, or biocompatibility
Glass filled polyamide (nylon) material for real-world physical testing and functional use. Excellent mechanical stiffness
and elevated temperature resistance. For Enclosures and housings that require more stiffness, sporting goods, aircraft and motorsports parts applications, etc.
DuraForm FR 100 Plastic - SLS Systems - Material properties (EN)Quoc Tuan Duong, ing.
In addition to meeting the flame retardancy necessary for many potential aerospace applications, DuraForm® FR100 has been formulated to reduce production of smoke and related toxic byproducts of combustion and achieve UL94 V-0 rating to meet the needs of today’s human environmental safety for many other consumer applications. For electrical appliances, aerospace and aircraft cabin, compartment & cargo applications, etc.
A durable, rubber-like material with good tear resistance and burst strength. Address broad applications requiring rubber-like flexibility and durability. For Gaskets, hoses and seals applications, etc.
Manufacture tough, impact-resistant plastic prototypes or
end-use parts requiring molded-part performance and
capable of withstanding harsh enviroments. Outstanding toughness and excellent impact resistance. For complex, thin-walled ductwork, consumer sporting goods, housings and enclosures applications, etc.
Directly produce complex investment casting patterns without tooling. Functions like foundry wax and is “foundry
friendly”. Create patterns directly rather than through
indirect methods
Get extreme performance and durability with Accura® Xtreme Plastic. Durability, impact resistance. For master patterns and CNC machining of polypropylene and ABS applications.
High stiffness, best in class moisture stability and elevated temperature resistance. For Test of water and fluid handling
components, wind tunnel models and master patterns applications.
Accura® e-Stone™ material is compatible with all intraoral and impression scanning systems that output an .stl file to produce accurate, durable models of individual teeth and arches with crisp resolution.
Water scarcity is the lack of fresh water resources to meet the standard water demand. There are two type of water scarcity. One is physical. The other is economic water scarcity.
Hybrid optimization of pumped hydro system and solar- Engr. Abdul-Azeez.pdffxintegritypublishin
Advancements in technology unveil a myriad of electrical and electronic breakthroughs geared towards efficiently harnessing limited resources to meet human energy demands. The optimization of hybrid solar PV panels and pumped hydro energy supply systems plays a pivotal role in utilizing natural resources effectively. This initiative not only benefits humanity but also fosters environmental sustainability. The study investigated the design optimization of these hybrid systems, focusing on understanding solar radiation patterns, identifying geographical influences on solar radiation, formulating a mathematical model for system optimization, and determining the optimal configuration of PV panels and pumped hydro storage. Through a comparative analysis approach and eight weeks of data collection, the study addressed key research questions related to solar radiation patterns and optimal system design. The findings highlighted regions with heightened solar radiation levels, showcasing substantial potential for power generation and emphasizing the system's efficiency. Optimizing system design significantly boosted power generation, promoted renewable energy utilization, and enhanced energy storage capacity. The study underscored the benefits of optimizing hybrid solar PV panels and pumped hydro energy supply systems for sustainable energy usage. Optimizing the design of solar PV panels and pumped hydro energy supply systems as examined across diverse climatic conditions in a developing country, not only enhances power generation but also improves the integration of renewable energy sources and boosts energy storage capacities, particularly beneficial for less economically prosperous regions. Additionally, the study provides valuable insights for advancing energy research in economically viable areas. Recommendations included conducting site-specific assessments, utilizing advanced modeling tools, implementing regular maintenance protocols, and enhancing communication among system components.
Industrial Training at Shahjalal Fertilizer Company Limited (SFCL)MdTanvirMahtab2
This presentation is about the working procedure of Shahjalal Fertilizer Company Limited (SFCL). A Govt. owned Company of Bangladesh Chemical Industries Corporation under Ministry of Industries.
Overview of the fundamental roles in Hydropower generation and the components involved in wider Electrical Engineering.
This paper presents the design and construction of hydroelectric dams from the hydrologist’s survey of the valley before construction, all aspects and involved disciplines, fluid dynamics, structural engineering, generation and mains frequency regulation to the very transmission of power through the network in the United Kingdom.
Author: Robbie Edward Sayers
Collaborators and co editors: Charlie Sims and Connor Healey.
(C) 2024 Robbie E. Sayers
Immunizing Image Classifiers Against Localized Adversary Attacksgerogepatton
This paper addresses the vulnerability of deep learning models, particularly convolutional neural networks
(CNN)s, to adversarial attacks and presents a proactive training technique designed to counter them. We
introduce a novel volumization algorithm, which transforms 2D images into 3D volumetric representations.
When combined with 3D convolution and deep curriculum learning optimization (CLO), itsignificantly improves
the immunity of models against localized universal attacks by up to 40%. We evaluate our proposed approach
using contemporary CNN architectures and the modified Canadian Institute for Advanced Research (CIFAR-10
and CIFAR-100) and ImageNet Large Scale Visual Recognition Challenge (ILSVRC12) datasets, showcasing
accuracy improvements over previous techniques. The results indicate that the combination of the volumetric
input and curriculum learning holds significant promise for mitigating adversarial attacks without necessitating
adversary training.
Explore the innovative world of trenchless pipe repair with our comprehensive guide, "The Benefits and Techniques of Trenchless Pipe Repair." This document delves into the modern methods of repairing underground pipes without the need for extensive excavation, highlighting the numerous advantages and the latest techniques used in the industry.
Learn about the cost savings, reduced environmental impact, and minimal disruption associated with trenchless technology. Discover detailed explanations of popular techniques such as pipe bursting, cured-in-place pipe (CIPP) lining, and directional drilling. Understand how these methods can be applied to various types of infrastructure, from residential plumbing to large-scale municipal systems.
Ideal for homeowners, contractors, engineers, and anyone interested in modern plumbing solutions, this guide provides valuable insights into why trenchless pipe repair is becoming the preferred choice for pipe rehabilitation. Stay informed about the latest advancements and best practices in the field.
CFD Simulation of By-pass Flow in a HRSG module by R&R Consult.pptxR&R Consult
CFD analysis is incredibly effective at solving mysteries and improving the performance of complex systems!
Here's a great example: At a large natural gas-fired power plant, where they use waste heat to generate steam and energy, they were puzzled that their boiler wasn't producing as much steam as expected.
R&R and Tetra Engineering Group Inc. were asked to solve the issue with reduced steam production.
An inspection had shown that a significant amount of hot flue gas was bypassing the boiler tubes, where the heat was supposed to be transferred.
R&R Consult conducted a CFD analysis, which revealed that 6.3% of the flue gas was bypassing the boiler tubes without transferring heat. The analysis also showed that the flue gas was instead being directed along the sides of the boiler and between the modules that were supposed to capture the heat. This was the cause of the reduced performance.
Based on our results, Tetra Engineering installed covering plates to reduce the bypass flow. This improved the boiler's performance and increased electricity production.
It is always satisfying when we can help solve complex challenges like this. Do your systems also need a check-up or optimization? Give us a call!
Work done in cooperation with James Malloy and David Moelling from Tetra Engineering.
More examples of our work https://www.r-r-consult.dk/en/cases-en/
Student information management system project report ii.pdfKamal Acharya
Our project explains about the student management. This project mainly explains the various actions related to student details. This project shows some ease in adding, editing and deleting the student details. It also provides a less time consuming process for viewing, adding, editing and deleting the marks of the students.
Design and Analysis of Algorithms-DP,Backtracking,Graphs,B&B
DuraForm PA Certification - USP class VI & ISO 10993 and Food contact FDA certification
1. 07 November 2013
REGULATORY INFORMATION SHEET
DuraForm® PA Powder
A. USP Class VI Certification
DuraForm PA powder has met the requirements of USP Class VI testing. Compliance is based on the
animal testing of a single batch which is considered representative of production.
B. ISO 10993 Certification
Based upon similar testing for USP Class VI, 3D Systems believes DuraForm PA powder should meet
the requirements of ISO 10993 sections for surface device/skin contact/limited duration.
C. Food Contact Certification
The components of this product are listed in regulations promulgated by the U.S. Food and Drug
Administration (FDA), 21CFR §177.1500 “Nylon Resins,” as resins that may be safely used to produce
articles intended for use in processing, handling and packaging non-alcoholic food. The restrictions
apply which are contained in §177.1500(b)(9) applicable to Nylon 12 resins.
The components of this product are also listed in the Plastic Directive of the European Union (EU),
No 10/2011and its amendments implementing the regulation (EC) No 1935/2004 for plastics, as
appropriate for use in food contact materials subject to the restrictions of:
1) Laurolactame (CAS # 947-04-6) SML=5ppm
2) 1,6-hexamethylene-bis(3-(3,5-di-tert-butyl-4-hydrooxyphenyl)propionamide)
(CAS # 23128-74-7) SML=45ppm
Based on these results, it is expected that similar articles made from these products, under conditions
of good manufacturing practice and according to 3D Systems recommendations, will meet the
compliance requirements of the cited regulations.
It is the responsibility of our customers to determine that their use of our product(s) is safe, lawful, and
technically suitable to their intended applications. Customers should conduct their own testing to
ensure that this is the case. Because of possible changes in the law and in regulations, as well as
possible changes in our products, we cannot guarantee that the status of this product will remain
unchanged. We, therefore, recommend that customers continuing to use this product verify its status
no less frequently than two years from the date of this publication.
For additional information about this product, please contact David Sloan, Operations Manager,
sloand@3dsystems.com.