Digital Fabrication Studio.01 discusses the history and concepts of digital fabrication (fabbing) and Fab Labs. It provides examples of how digital fabrication is used from craft projects to industrial manufacturing. It outlines the key aspects of Fab Labs as spaces that democratize digital fabrication technologies and allow for collaborative exploration and project development. Applications of digital fabrication discussed include DIY and hacker projects, generative design, mass customization, customized prosthetics, shorter supply chains, and use in different media like photography, video, and books.