The document summarizes the key digestive processes in humans. It describes digestion as involving the mixing of food, its movement through the digestive tract, and the chemical breakdown of large food molecules into smaller ones. The major digestive processes are ingestion, propulsion, mechanical and chemical digestion, absorption, and defecation. Mechanical digestion breaks food into smaller pieces physically, while chemical digestion uses enzymes to break molecules down chemically starting in the mouth and finishing in the small intestine.
THIS PRESENTATION INCLUDES DETAILED INFORMATION ABOUT ACCESSORY ORGANS OF DIGESTIVE SYSTEM..i,e TEETH, TONGUE, SALIVARY GLANDS, PANCREAS, LIVER AND GALL BLADDER
Human digestive system structure and function
overview
Major organs
Mouth
Esophagus
Stomach
small intestine
large intestine
Acessory organs:
Liver
gall bladder
Pancreas.
Human digestive system
Major organs
Mouth
Esophagus
Stomach
small intestine
large intestine.
Acessory organs:
Liver
Gall bladder
Pancreas.
MAJOR ORGANSThe Mouth
pH: 7
The first part of the digestive system
the entry point of food.
Structures in the mouth that aids digestion
Teeth – cut, tear, crush and grind food.
Salivary glands – produce and secrete saliva into the oral cavity.
saliva
moistens the food
contains enzymes (ptyalin or salivary amylase)
begins digestion of starch into smaller polysaccharides.
Function:
Mechanical digestion.
increasing surface area for faster chemical digestion.
The Esophagus
a tube connecting the mouth to the stomach
running through the Thoracic cavity.
Location:
lies behind windpipe (Trachea).
The trachea has as an epiglottis
preventing food from entering the windpipe,
moving the food to the esophagus while swallowing.
Food travels down the esophagus, through a series of involuntary rhythmic contractions (wave-like) called peristalsis.
Function:
The lining of the esophagus secretes mucus
lubricating
to support the movement of food.
Esophageal sphincter:
bolus reaches the stomach
must pass through a muscular ringed valve called the esophageal sphincter (Cardiac Sphincter).
Function:
prevent stomach acids from back flowing into the esophagus.
Stomach
J-shaped muscular sac
Has inner folds (rugae)
Increasing surface area of the stomach.
Function:
Stomach performs mechanical digestion
HOW By churning the bolus and mixing it with the gastric juices
secreted by the lining of the stomach.
GASTRIC JUICES HCl, salts, enzymes, water and mucus)
HCL helps break down of food and kills bacteria that came along with the food.
The bolus is now called Chyme.
Enzymes in stomach:
Acidic environment
HCl secreation
kill any microbes that are found in the bolus,
creating a pH of 2.
Mucus prevents the stomach from digesting itself.
Pepsin secreation
responsible for initiating the breakdown of proteins (in )food.
hydrolyzes proteins to yield polypeptides.
pH is 2, the enzyme from the salivary glands stops breaking down carbohydrates.
Pyloric sphincter:
chyme moves from the stomach to the small intestine.
It passes through a muscular ringed sphincter called the pyloric sphincter.
stomach does not digest itselfWhy ?
Protective Mechanism:
three protective mechanisms.
First the stomach only secretes small amounts of gastric juices until food is present.
Second the secretion of mucus coats the lining of the stomach protecting it from the gastric juices.
The third mechanism is the digestive enzyme pepsin is secreted in an inactive protein c
The digestive system includes the organs of the alimentary canal and accessory structures. The alimentary canal forms a continuous tube that is open to the outside environment at both ends. The organs of the alimentary canal are the mouth, pharynx, esophagus, stomach, small intestine, and large intestine.
Human kidney,structure and functions of kidneyAnand P P
human kidney structural and functions.different types of structural components present in kidney and each structure having definite functions.structural and functional aspects of kidney.
THIS PRESENTATION INCLUDES DETAILED INFORMATION ABOUT ACCESSORY ORGANS OF DIGESTIVE SYSTEM..i,e TEETH, TONGUE, SALIVARY GLANDS, PANCREAS, LIVER AND GALL BLADDER
Human digestive system structure and function
overview
Major organs
Mouth
Esophagus
Stomach
small intestine
large intestine
Acessory organs:
Liver
gall bladder
Pancreas.
Human digestive system
Major organs
Mouth
Esophagus
Stomach
small intestine
large intestine.
Acessory organs:
Liver
Gall bladder
Pancreas.
MAJOR ORGANSThe Mouth
pH: 7
The first part of the digestive system
the entry point of food.
Structures in the mouth that aids digestion
Teeth – cut, tear, crush and grind food.
Salivary glands – produce and secrete saliva into the oral cavity.
saliva
moistens the food
contains enzymes (ptyalin or salivary amylase)
begins digestion of starch into smaller polysaccharides.
Function:
Mechanical digestion.
increasing surface area for faster chemical digestion.
The Esophagus
a tube connecting the mouth to the stomach
running through the Thoracic cavity.
Location:
lies behind windpipe (Trachea).
The trachea has as an epiglottis
preventing food from entering the windpipe,
moving the food to the esophagus while swallowing.
Food travels down the esophagus, through a series of involuntary rhythmic contractions (wave-like) called peristalsis.
Function:
The lining of the esophagus secretes mucus
lubricating
to support the movement of food.
Esophageal sphincter:
bolus reaches the stomach
must pass through a muscular ringed valve called the esophageal sphincter (Cardiac Sphincter).
Function:
prevent stomach acids from back flowing into the esophagus.
Stomach
J-shaped muscular sac
Has inner folds (rugae)
Increasing surface area of the stomach.
Function:
Stomach performs mechanical digestion
HOW By churning the bolus and mixing it with the gastric juices
secreted by the lining of the stomach.
GASTRIC JUICES HCl, salts, enzymes, water and mucus)
HCL helps break down of food and kills bacteria that came along with the food.
The bolus is now called Chyme.
Enzymes in stomach:
Acidic environment
HCl secreation
kill any microbes that are found in the bolus,
creating a pH of 2.
Mucus prevents the stomach from digesting itself.
Pepsin secreation
responsible for initiating the breakdown of proteins (in )food.
hydrolyzes proteins to yield polypeptides.
pH is 2, the enzyme from the salivary glands stops breaking down carbohydrates.
Pyloric sphincter:
chyme moves from the stomach to the small intestine.
It passes through a muscular ringed sphincter called the pyloric sphincter.
stomach does not digest itselfWhy ?
Protective Mechanism:
three protective mechanisms.
First the stomach only secretes small amounts of gastric juices until food is present.
Second the secretion of mucus coats the lining of the stomach protecting it from the gastric juices.
The third mechanism is the digestive enzyme pepsin is secreted in an inactive protein c
The digestive system includes the organs of the alimentary canal and accessory structures. The alimentary canal forms a continuous tube that is open to the outside environment at both ends. The organs of the alimentary canal are the mouth, pharynx, esophagus, stomach, small intestine, and large intestine.
Human kidney,structure and functions of kidneyAnand P P
human kidney structural and functions.different types of structural components present in kidney and each structure having definite functions.structural and functional aspects of kidney.
The excretory system is a passive biological system that removes excess, unnecessary materials from the body fluids of an organism, so as to help maintain internal chemical homeostasis and prevent damage to the body.
Digestion is the breakdown of large insoluble food molecules into small water-soluble food molecules so that they can be absorbed into the watery blood plasma. In certain organisms, these smaller substances are absorbed through the small intestine into the blood stream.
he sense organs — eyes, ears, tongue, skin, and nose — help to protect the body. The human sense organs contain receptors that relay information through sensory neurons to the appropriate places within the nervous system.
Each sense organ contains different receptors.
General receptors are found throughout the body because they are present in skin, visceral organs (visceral meaning in the abdominal cavity), muscles, and joints.
Special receptors include chemoreceptors (chemical receptors) found in the mouth and nose, photoreceptors (light receptors) found in the eyes, and mechanoreceptors found in the ears.
In humans, the respiratory tract is the part of the anatomy of the respiratory system involved with the process of respiration. Air is breathed in through the nose or the mouth. In the nasal cavity, a layer of mucous membrane acts as a filter and traps pollutants and other harmful substances found in the air.
753 Learning OutcomesAfter reading this chapter, .docxpoulterbarbara
75
3
Learning Outcomes
After reading this chapter, you will be able to:
3.1 Describe the processes and organs involved in
digestion.
3.2 Explain how food is propelled through the gas-
trointestinal tract.
3.3 Identify the role of enzymes and other secre-
tions in chemical digestion.
3.4 Describe how digested nutrients are absorbed.
3.5 Explain how hormones and the nervous sys-
tem regulate digestion.
3.6 Explain how absorbed nutrients are trans-
ported throughout the body.
3.7 Discuss the most common digestive disorders.
True or False?
1. Saliva can alter the taste of food. T/F
2. Without mucus, the stomach would digest itself. T/F
3. The major function of bile is to emulsify fats. T/F
4. Acid reflux is caused by gas in the stom-ach. T/F
5. The primary function of the large intes-tine is to absorb water. T/F
6. Feces contain a high amount of bacteria. T/F
7. The lymphatic system transports all nutrients through the body once they’ve been absorbed. T/F
8. Hormones play an important role in digestion. T/F
9. Diarrhea is always caused by bacterial infection. T/F
10. Irritable bowel syndrome is caused by an allergy to gluten. T/F
See page 110 for the answers.
Digestion,
Absorption,
and Transport
M03_BLAK8260_04_SE_C03.indd 75 12/1/17 11:28 PM
76 Chapter 3 | Digestion, Absorption, and Transport
The digestion of food begins even before you take that first bite. Just the sight and smell of homemade apple pie stimulates the release of saliva in
the mouth. The secretion of saliva and other digestive juices starts a cascade of
events that prepares the body for digestion, the chemical and mechanical
processes by which the body breaks food down into individual nutrient
molecules ready for absorption. Food components that aren’t absorbed are
excreted as waste (feces) by elimination. Although these are complex
processes, they go largely unnoticed. You consciously chew and swallow the
pie, but you don’t feel the release of chemicals or the muscular contractions
that cause it to be digested or the absorption of nutrient molecules through
the intestinal lining cells. In fact, you may be unaware of the entire process
until about 48 hours after eating, when the body is ready to eliminate waste.
In this chapter, we explore the processes of digestion, absorption, and
elimination, the organs involved, and the other biological mechanisms that
regulate our bodies’ processing of food and nutrients. We also discuss the causes
and treatments of some common gastrointestinal conditions and disorders.
What Are the Processes and Organs
Involved in Digestion?
LO 3.1 Describe the processes and organs involved in digestion.
Digestion, absorption, and elimination occur in the gastrointestinal (GI) tract, a mus-
cular tube approximately 20–24 feet long in an adult. Stretched vertically, the tube would
be about as high as a two-story building. It provides a barrier between the food within the
lumen (the hollow .
The excretory system is a passive biological system that removes excess, unnecessary materials from the body fluids of an organism, so as to help maintain internal chemical homeostasis and prevent damage to the body.
Digestion is the breakdown of large insoluble food molecules into small water-soluble food molecules so that they can be absorbed into the watery blood plasma. In certain organisms, these smaller substances are absorbed through the small intestine into the blood stream.
he sense organs — eyes, ears, tongue, skin, and nose — help to protect the body. The human sense organs contain receptors that relay information through sensory neurons to the appropriate places within the nervous system.
Each sense organ contains different receptors.
General receptors are found throughout the body because they are present in skin, visceral organs (visceral meaning in the abdominal cavity), muscles, and joints.
Special receptors include chemoreceptors (chemical receptors) found in the mouth and nose, photoreceptors (light receptors) found in the eyes, and mechanoreceptors found in the ears.
In humans, the respiratory tract is the part of the anatomy of the respiratory system involved with the process of respiration. Air is breathed in through the nose or the mouth. In the nasal cavity, a layer of mucous membrane acts as a filter and traps pollutants and other harmful substances found in the air.
753 Learning OutcomesAfter reading this chapter, .docxpoulterbarbara
75
3
Learning Outcomes
After reading this chapter, you will be able to:
3.1 Describe the processes and organs involved in
digestion.
3.2 Explain how food is propelled through the gas-
trointestinal tract.
3.3 Identify the role of enzymes and other secre-
tions in chemical digestion.
3.4 Describe how digested nutrients are absorbed.
3.5 Explain how hormones and the nervous sys-
tem regulate digestion.
3.6 Explain how absorbed nutrients are trans-
ported throughout the body.
3.7 Discuss the most common digestive disorders.
True or False?
1. Saliva can alter the taste of food. T/F
2. Without mucus, the stomach would digest itself. T/F
3. The major function of bile is to emulsify fats. T/F
4. Acid reflux is caused by gas in the stom-ach. T/F
5. The primary function of the large intes-tine is to absorb water. T/F
6. Feces contain a high amount of bacteria. T/F
7. The lymphatic system transports all nutrients through the body once they’ve been absorbed. T/F
8. Hormones play an important role in digestion. T/F
9. Diarrhea is always caused by bacterial infection. T/F
10. Irritable bowel syndrome is caused by an allergy to gluten. T/F
See page 110 for the answers.
Digestion,
Absorption,
and Transport
M03_BLAK8260_04_SE_C03.indd 75 12/1/17 11:28 PM
76 Chapter 3 | Digestion, Absorption, and Transport
The digestion of food begins even before you take that first bite. Just the sight and smell of homemade apple pie stimulates the release of saliva in
the mouth. The secretion of saliva and other digestive juices starts a cascade of
events that prepares the body for digestion, the chemical and mechanical
processes by which the body breaks food down into individual nutrient
molecules ready for absorption. Food components that aren’t absorbed are
excreted as waste (feces) by elimination. Although these are complex
processes, they go largely unnoticed. You consciously chew and swallow the
pie, but you don’t feel the release of chemicals or the muscular contractions
that cause it to be digested or the absorption of nutrient molecules through
the intestinal lining cells. In fact, you may be unaware of the entire process
until about 48 hours after eating, when the body is ready to eliminate waste.
In this chapter, we explore the processes of digestion, absorption, and
elimination, the organs involved, and the other biological mechanisms that
regulate our bodies’ processing of food and nutrients. We also discuss the causes
and treatments of some common gastrointestinal conditions and disorders.
What Are the Processes and Organs
Involved in Digestion?
LO 3.1 Describe the processes and organs involved in digestion.
Digestion, absorption, and elimination occur in the gastrointestinal (GI) tract, a mus-
cular tube approximately 20–24 feet long in an adult. Stretched vertically, the tube would
be about as high as a two-story building. It provides a barrier between the food within the
lumen (the hollow .
The digestive system of the human body comprises a group of organs working together to convert food into energy for the body. Human Digestive System and Nutrition involve the intake of food by an organism and its utilization for energy. This is a vital process which helps living beings to obtain their energy from various sources. The food which we eat undergoes much processing before the nutrients present in them are utilized to generate energy. This processing is known as digestion. The digestion process involves the alimentary canal along with various accessory organs and organ systems. In humans, the process is quite simple due to our monogastric nature. This means that we have a one-chambered stomach, unlike other animals such as cows, which have four chambers.
Science Grade 8- The Digestive System.pptxnairamarano
The Digestive System- Science (Biology)Grade 8
The food that we eat plays a central role in the survival of species. It provides the energy that enables us to carry out the many activities that we do each day such as breathing, walking, studying and cooking. Food also provides the substances needed for growth and repair of body parts.
IDENTIFYING CHARACTERISTICS OF IMPORTANT EDIBLE CRUSTACEANS.pptxDr. Karri Ramarao
Crabs, prawns, crayfish and lobster are examples of edible crustaceans that are among the main sources of nutrient-rich food for people. A crustacean's nutritional value is determined by its biochemical makeup, which includes its protein, amino acids, lipids, fatty acids, carbohydrates, vitamins, and minerals.
Habitat: All ctenophores are exclusively marine.
Habits: They feed on plankton, swim by cilia. Power of regeneration is well marked. Bioluminescence
Body form is variable
Symmetry:
Symmetry is biradial (radial + bilateral).
The spicules or sclerites are definite bodies, having a crystalline appearance and consisting in general of simple spines or of spines radiating from a point.
They have an axis of organic material around which is deposited the inorganic substance, either calcium carbonate or hydrated silica.
A number of different substances are used as liming materials, the chemical used for the liming of soil and water are the oxides, hydroxides and silicates of calcium or magnesium
Gynogenesis, a form of Parthenogensis, is a system of asexual reproduction that requires the presence of sperm without the actual contribution of its DNA for completion. The paternal DNA dissolves or is destroyed before it can fuse with the egg
A Secchi disk is a metal disk, 8 inches (20 centimeter) in diameter, It is an 8-inch (20 centimeter) diameter, black and white disk attached to a dowel rod, PVC pipe, rope or chain The depth that the Secchi disk can no longer be seen through the water is the Secchi depth.
Biostatistics is also known as biometry, the development and application of statistical methods to a wide range of topics in biology. It encompasses the design of biological experiments, the collection and analysis of data from those experiments and the interpretation of the results.
The alimentary canal of Scoliodon comprises:
the mouth,
buccal cavity,
pharynx,
oesophagus,
stomach,
intestine and
rectum opening in the cloaca through anus.
Fishes possess dermal scales on the body for protection. Each scale is made of dentine that is secreted by dermal papilla which is a group of specialized neighbouring tissues. The exposed
portion of scale is covered with a layer of hard enamel to minimise wear and tear. Ancient
fishes generally had thick bony scales while the modern fishes have evolved thin and flexible
scales for more agility.
Catadromous migration: The movement of large number of individuals from fresh water to sea water, generally for spawning as happens in the case of eels.
Anadromous fishes live and feed in ocean waters but their spawning grounds lie in the tributaries of rivers.
Fish culture is classified based on the number of fish species as monoculture and polyculture. This is the culture of single species of fish in a pond or tank. The culture of trout, tilapia, catfish , carps are typical examples of monoculture.
Classification of Nematodes
Nematodes are classified into the following classes:
1. Phasmidia or Secernentea
• These are mostly parasitic.
• Caudal glands are absent.
• Unicellular, pouch-like sense organs called plasmids are present.
• The excretory system has paired lateral canals.
• Eg., Ascaris, Enterobius
2. Aphasmidia or Adenophorea
• They are free-living organisms.
• The excretory system has no lateral canals.
• Caudal glands are present.
• Phasmids are absent.
• Eg., Capillaria, Trichinella
The most common fish diseases, particularly in freshwater aquaria, include columnaris, gill disease, ick (ich), dropsy, tail and fin-rot, fungal infections, white spot disease, pop-eye, cloudy eye, swim bladder disease, lice and nematode worms infestation, water quality induced diseases, constipation, anorexia, ...
Identification and study of important cultivable FishesDr. Karri Ramarao
In India mostly major carps are use to cultivable freshwater fish and some catfish also use to culture. The important cultivable species are Catla catla, Labeo rohita, Cirrhinus mrigalaIn India mostly major carps are use to cultivable fish and some catfish also use to culture. The important cultivable saline water species areMugils, Lates etc,.
Richard's aventures in two entangled wonderlandsRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Introduction:
RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is an important biological process for modulating eukaryotic gene expression.
It is highly conserved process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) causes sequence-specific degradation of mRNA sequences.
dsRNA-induced gene silencing (RNAi) is reported in a wide range of eukaryotes ranging from worms, insects, mammals and plants.
This process mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes.
What are small ncRNAs?
micro RNA (miRNA)
short interfering RNA (siRNA)
Properties of small non-coding RNA:
Involved in silencing mRNA transcripts.
Called “small” because they are usually only about 21-24 nucleotides long.
Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered).
Silence an mRNA by base pairing with some sequence on the mRNA.
Discovery of siRNA?
The first small RNA:
In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the
development of the worm C. elegans.
Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14.
Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions.
Types of RNAi ( non coding RNA)
MiRNA
Length (23-25 nt)
Trans acting
Binds with target MRNA in mismatch
Translation inhibition
Si RNA
Length 21 nt.
Cis acting
Bind with target Mrna in perfect complementary sequence
Piwi-RNA
Length ; 25 to 36 nt.
Expressed in Germ Cells
Regulates trnasposomes activity
MECHANISM OF RNAI:
First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces.
Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands.
The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it.
THE RISC COMPLEX:
RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA
Unwinding of double stranded Si RNA by ATP independent Helicase
Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA.
DICER: endonuclease (RNase Family III)
Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC)
One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute
ARGONAUTE PROTEIN :
1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA
2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity.
MiRNA:
The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .
(May 29th, 2024) Advancements in Intravital Microscopy- Insights for Preclini...Scintica Instrumentation
Intravital microscopy (IVM) is a powerful tool utilized to study cellular behavior over time and space in vivo. Much of our understanding of cell biology has been accomplished using various in vitro and ex vivo methods; however, these studies do not necessarily reflect the natural dynamics of biological processes. Unlike traditional cell culture or fixed tissue imaging, IVM allows for the ultra-fast high-resolution imaging of cellular processes over time and space and were studied in its natural environment. Real-time visualization of biological processes in the context of an intact organism helps maintain physiological relevance and provide insights into the progression of disease, response to treatments or developmental processes.
In this webinar we give an overview of advanced applications of the IVM system in preclinical research. IVIM technology is a provider of all-in-one intravital microscopy systems and solutions optimized for in vivo imaging of live animal models at sub-micron resolution. The system’s unique features and user-friendly software enables researchers to probe fast dynamic biological processes such as immune cell tracking, cell-cell interaction as well as vascularization and tumor metastasis with exceptional detail. This webinar will also give an overview of IVM being utilized in drug development, offering a view into the intricate interaction between drugs/nanoparticles and tissues in vivo and allows for the evaluation of therapeutic intervention in a variety of tissues and organs. This interdisciplinary collaboration continues to drive the advancements of novel therapeutic strategies.
Observation of Io’s Resurfacing via Plume Deposition Using Ground-based Adapt...Sérgio Sacani
Since volcanic activity was first discovered on Io from Voyager images in 1979, changes
on Io’s surface have been monitored from both spacecraft and ground-based telescopes.
Here, we present the highest spatial resolution images of Io ever obtained from a groundbased telescope. These images, acquired by the SHARK-VIS instrument on the Large
Binocular Telescope, show evidence of a major resurfacing event on Io’s trailing hemisphere. When compared to the most recent spacecraft images, the SHARK-VIS images
show that a plume deposit from a powerful eruption at Pillan Patera has covered part
of the long-lived Pele plume deposit. Although this type of resurfacing event may be common on Io, few have been detected due to the rarity of spacecraft visits and the previously low spatial resolution available from Earth-based telescopes. The SHARK-VIS instrument ushers in a new era of high resolution imaging of Io’s surface using adaptive
optics at visible wavelengths.
Nutraceutical market, scope and growth: Herbal drug technologyLokesh Patil
As consumer awareness of health and wellness rises, the nutraceutical market—which includes goods like functional meals, drinks, and dietary supplements that provide health advantages beyond basic nutrition—is growing significantly. As healthcare expenses rise, the population ages, and people want natural and preventative health solutions more and more, this industry is increasing quickly. Further driving market expansion are product formulation innovations and the use of cutting-edge technology for customized nutrition. With its worldwide reach, the nutraceutical industry is expected to keep growing and provide significant chances for research and investment in a number of categories, including vitamins, minerals, probiotics, and herbal supplements.
This pdf is about the Schizophrenia.
For more details visit on YouTube; @SELF-EXPLANATORY;
https://www.youtube.com/channel/UCAiarMZDNhe1A3Rnpr_WkzA/videos
Thanks...!
The increased availability of biomedical data, particularly in the public domain, offers the opportunity to better understand human health and to develop effective therapeutics for a wide range of unmet medical needs. However, data scientists remain stymied by the fact that data remain hard to find and to productively reuse because data and their metadata i) are wholly inaccessible, ii) are in non-standard or incompatible representations, iii) do not conform to community standards, and iv) have unclear or highly restricted terms and conditions that preclude legitimate reuse. These limitations require a rethink on data can be made machine and AI-ready - the key motivation behind the FAIR Guiding Principles. Concurrently, while recent efforts have explored the use of deep learning to fuse disparate data into predictive models for a wide range of biomedical applications, these models often fail even when the correct answer is already known, and fail to explain individual predictions in terms that data scientists can appreciate. These limitations suggest that new methods to produce practical artificial intelligence are still needed.
In this talk, I will discuss our work in (1) building an integrative knowledge infrastructure to prepare FAIR and "AI-ready" data and services along with (2) neurosymbolic AI methods to improve the quality of predictions and to generate plausible explanations. Attention is given to standards, platforms, and methods to wrangle knowledge into simple, but effective semantic and latent representations, and to make these available into standards-compliant and discoverable interfaces that can be used in model building, validation, and explanation. Our work, and those of others in the field, creates a baseline for building trustworthy and easy to deploy AI models in biomedicine.
Bio
Dr. Michel Dumontier is the Distinguished Professor of Data Science at Maastricht University, founder and executive director of the Institute of Data Science, and co-founder of the FAIR (Findable, Accessible, Interoperable and Reusable) data principles. His research explores socio-technological approaches for responsible discovery science, which includes collaborative multi-modal knowledge graphs, privacy-preserving distributed data mining, and AI methods for drug discovery and personalized medicine. His work is supported through the Dutch National Research Agenda, the Netherlands Organisation for Scientific Research, Horizon Europe, the European Open Science Cloud, the US National Institutes of Health, and a Marie-Curie Innovative Training Network. He is the editor-in-chief for the journal Data Science and is internationally recognized for his contributions in bioinformatics, biomedical informatics, and semantic technologies including ontologies and linked data.
2. Digestion involves the mixing
of food, its movement through
the digestive tract, and the chemical
breakdown of the large molecules
of food into smaller molecules.
Digestion begins in the mouth, when
we chew and swallow,
and is completed in the small
intestine.
3. The digestive system
uses mechanical and
chemical activities to
break food down into
absorbable substances
during its journey
through the digestive
system.
4. Digestive Processes.
The processes of digestion include
six activities: ingestion, propulsion,
mechanical or physical digestion,
chemical digestion, absorption, and
defecation.
The first of these processes,
ingestion, refers to the entry of
food into the alimentary canal
through the mouth.
5. Organ Major functions Other functions
Mouth
Ingests food
Chews and mixes food
Begins chemical breakdown
of carbohydrates
Moves food into the pharynx
Begins breakdown of lipids
via lingual lipase
Moistens and dissolves
food, allowing you to
taste it
Cleans and lubricates the
teeth and oral cavity
Has some antimicrobial
activity
Pharynx
Propels food from the oral
cavity to the esophagus
Lubricates food and
passageways
Functions of the Digestive Organs
6. Organ Major functions Other functions
Esophagus Propels food to the stomach
Lubricates food and
passageways
Stomach
Mixes and churns food with gastric
juices to form chyme
Begins chemical breakdown of
proteins
Releases food into the duodenum as
chyme
Absorbs some fat-soluble
substances (for example, alcohol,
aspirin)
Possesses antimicrobial functions
Stimulates protein-
digesting enzymes
Secretes intrinsic
factor required for
vitamin
B12 absorption in
small intestine
7. Organ Major functions
Other
functions
Small
intestine
Mixes chyme with digestive juices
Propels food at a rate slow enough for
digestion and absorption.
Absorbs breakdown products of
carbohydrates, proteins, lipids, and
nucleic acids, along with vitamins,
minerals, and water
Performs physical digestion via
segmentation
Provides
optimal
medium
for
enzymatic
activity
8. Organ Major functions Other functions
Accessory
organs
Liver: produces bile salts, which
emulsify lipids, aiding their
digestion and absorption
Gallbladder: stores,
concentrates, and releases bile
Pancreas: produces digestive
enzymes and bicarbonate
Bicarbonate-rich pancreatic
juices help neutralize acidic
chyme and provide optimal
environment for enzymatic
activity
Large
intestine
Further breaks down food
residues
Absorbs most residual water,
electrolytes, and vitamins
produced by enteric bacteria
Propels feces toward rectum
Eliminates feces
Food residue is
concentrated and
temporarily stored prior to
defecation
Mucus eases passage of
feces through colon
9. Digestive Processes
The processes of digestion include six
activities: ingestion, propulsion, mechanical
or physical digestion, chemical digestion,
absorption, and defecation.
The first of these processes, ingestion,
refers to the entry of food into the alimentary
canal through the mouth.
10. There, the food is chewed and mixed with
saliva, which contains enzymes that begin
breaking down the carbohydrates in the food
plus some lipid digestion via lingual lipase.
Chewing increases the surface area of the
food and allows an appropriately sized bolus
to be produced.
Food leaves the mouth when the tongue and
pharyngeal muscles propel it into the
esophagus.
11. This act of swallowing, the last voluntary act
until defecation, is an example
of propulsion, which refers to the
movement of food through the digestive
tract.
It includes both the voluntary process of
swallowing and the involuntary process of
peristalsis.
12. Fig 1. Peristalsis moves
food through the digestive
tract with alternating
waves of muscle
contraction and
relaxation.
Peristalsis consists of sequential,
alternating waves of contraction and
relaxation of alimentary wall smooth muscles,
which act to propel food along. These waves
also play a role in mixing food with digestive
juices.
13. Peristalsis is so powerful that foods and
liquids you swallow enter your stomach even
if you are standing on your head.
Digestion includes both mechanical and
chemical processes.
Mechanical digestion is a purely physical
process that does not change the chemical
nature of the food. Instead, it makes the
food smaller to increase both surface area
and mobility.
14. It includes mastication, or chewing, as well as
tongue movements that help break food into
smaller bits and mix food with saliva.
Although there may be a tendency to think
that mechanical digestion is limited to the
first steps of the digestive process, it occurs
after the food leaves the mouth, as well.
15.
16. The mechanical churning of food in the
stomach serves to further break it apart and
expose more of its surface area to digestive
juices, creating an acidic “soup”
called chyme.
Segmentation, which occurs mainly in the
small intestine, consists of localized
contractions of circular muscle of the
muscularis layer of the alimentary canal.
17. These contractions isolate small sections of
the intestine, moving their contents back and
forth while continuously subdividing,
breaking up, and mixing the contents.
By moving food back and forth in the
intestinal lumen, segmentation mixes food
with digestive juices and facilitates
absorption.
18. In chemical digestion, starting in the
mouth, digestive secretions break down
complex food molecules into their chemical
building blocks (for example, proteins into
separate amino acids).
These secretions vary in composition, but
typically contain water, various enzymes,
acids, and salts. The process is completed in
the small intestine.
19. Food that has been broken down is of no
value to the body unless it enters the
bloodstream and its nutrients are put to work.
This occurs through the process
of absorption, which takes place primarily
within the small intestine.
There, most nutrients are absorbed from the
lumen of the alimentary canal into the
bloodstream through the epithelial cells that
make up the mucosa.
20. Lipids are absorbed into lacteals and are
transported via the lymphatic vessels to the
bloodstream (the subclavian veins near the
heart). The details of these processes will be
discussed later.
In defecation, the final step in digestion,
undigested materials are removed from the
body as feces.
21. In some cases, a single organ is in charge of
a digestive process. For example, ingestion
occurs only in the mouth and defecation
only in the anus.
However, most digestive processes involve
the interaction of several organs and occur
gradually as food moves through the
alimentary canal
22. Fig: 2. The
digestive
processes are
ingestion,
propulsion,
mechanical
digestion,
chemical
digestion,
absorption,
and
defecation.