Addiction is a chronic, relapsing disease characterized by compulsive drug seeking and abuse. It requires long-term treatment to help arrest the progression of the disease and allow improved functioning. The presentation discussed addiction and commonly abused psychoactive substances. It outlined treatment objectives like intervention, detoxification, and rehabilitation through individual counseling, family counseling, group therapy, and aftercare. Homoeopathic constitutional remedies like Nux vomica, Sulphuric acid and Sulphur are recommended, especially for withdrawal symptoms.