This document discusses substance abuse and psychiatric disorders related to substance abuse. It covers various substances that are commonly abused like alcohol, opioids, cannabis, cocaine, and others. It describes the biological, psychological, and social factors contributing to substance abuse. It then outlines several psychiatric disorders that can result from substance abuse like alcohol dependence syndrome, opioid disorder, cannabis use disorder, and others. The document discusses the consequences of substance abuse and treatments for alcohol and opioid disorders. It provides prevention strategies and rehabilitation approaches for substance abuse disorders.