IB Biology markscheme, past exam papers, notes and 2012 IB Biology syllabus. IB Biology option D evolution markscheme. IB Biology option D evolution notes, IB Biology option D Evolution exam papers, IB Biology option E markscheme, IB Biology option E notes, IB Biology option E Neurobiology papers, IB Biology Option A Human Nutrition and Health syllabus 2012, Stimulus and response, Homologous structures, Pavlov experiments.
- Definition of lysosome
- Structure of lysosome
- Discovery of lysosome
- Synthesis of primary and secondary lysosome
- Functions of lysosome
- 4 intracellular processes by lysosome – phagocytosis, exocytosis, endocytosis and autolysis
- Definition of lysosome
- Structure of lysosome
- Discovery of lysosome
- Synthesis of primary and secondary lysosome
- Functions of lysosome
- 4 intracellular processes by lysosome – phagocytosis, exocytosis, endocytosis and autolysis
transduction is a mode of horizontal gene transfer in which the recipient does not come in contact with the donor bacterial cell, it is mediated by temperate phages.
This presentation covers a general introduction to expression vector, its components, types, and its application. Then it covers some of the expression system with examples.
Basics only
A variety of small cellular components bounded by single membrane found in Plant and
animal cell. Microbodies are of two types; Peroxisomes and glyoxysomes
Prokaryotic dna replication by kk sahuKAUSHAL SAHU
INTRODUCTION
HISTORY
TYPES OF DNA REPLICATION
ENZYMES AND PROTEINS INVOLVED
IN PROKARYOTIC DNA REPLICATION
MECHANISM OF PROKARYOTIC DNA
REPLICATION
INITIATION
ELONGATION
TERMINATION
CONCLUSION
REFERENCES
transduction is a mode of horizontal gene transfer in which the recipient does not come in contact with the donor bacterial cell, it is mediated by temperate phages.
This presentation covers a general introduction to expression vector, its components, types, and its application. Then it covers some of the expression system with examples.
Basics only
A variety of small cellular components bounded by single membrane found in Plant and
animal cell. Microbodies are of two types; Peroxisomes and glyoxysomes
Prokaryotic dna replication by kk sahuKAUSHAL SAHU
INTRODUCTION
HISTORY
TYPES OF DNA REPLICATION
ENZYMES AND PROTEINS INVOLVED
IN PROKARYOTIC DNA REPLICATION
MECHANISM OF PROKARYOTIC DNA
REPLICATION
INITIATION
ELONGATION
TERMINATION
CONCLUSION
REFERENCES
Life, living matter are those that shows certain attributes that include responsiveness, growth, metabolism, energy transformation and reproduction.
In biology origin of life or abiogenesis is the natural process by which life has arisen from non-living matter, such as simple organic compounds.
It means the emergence of heritable and evolvable self-reproduction.
It is a complex subject and oftentimes controversial.
Several attempts have been made from time to time to explain the origin of life on earth.
There are several theories which offer their own explanation on the possible mechanism of origin of life.
Embracing GenAI - A Strategic ImperativePeter Windle
Artificial Intelligence (AI) technologies such as Generative AI, Image Generators and Large Language Models have had a dramatic impact on teaching, learning and assessment over the past 18 months. The most immediate threat AI posed was to Academic Integrity with Higher Education Institutes (HEIs) focusing their efforts on combating the use of GenAI in assessment. Guidelines were developed for staff and students, policies put in place too. Innovative educators have forged paths in the use of Generative AI for teaching, learning and assessments leading to pockets of transformation springing up across HEIs, often with little or no top-down guidance, support or direction.
This Gasta posits a strategic approach to integrating AI into HEIs to prepare staff, students and the curriculum for an evolving world and workplace. We will highlight the advantages of working with these technologies beyond the realm of teaching, learning and assessment by considering prompt engineering skills, industry impact, curriculum changes, and the need for staff upskilling. In contrast, not engaging strategically with Generative AI poses risks, including falling behind peers, missed opportunities and failing to ensure our graduates remain employable. The rapid evolution of AI technologies necessitates a proactive and strategic approach if we are to remain relevant.
Model Attribute Check Company Auto PropertyCeline George
In Odoo, the multi-company feature allows you to manage multiple companies within a single Odoo database instance. Each company can have its own configurations while still sharing common resources such as products, customers, and suppliers.
Unit 8 - Information and Communication Technology (Paper I).pdfThiyagu K
This slides describes the basic concepts of ICT, basics of Email, Emerging Technology and Digital Initiatives in Education. This presentations aligns with the UGC Paper I syllabus.
Acetabularia Information For Class 9 .docxvaibhavrinwa19
Acetabularia acetabulum is a single-celled green alga that in its vegetative state is morphologically differentiated into a basal rhizoid and an axially elongated stalk, which bears whorls of branching hairs. The single diploid nucleus resides in the rhizoid.
Honest Reviews of Tim Han LMA Course Program.pptxtimhan337
Personal development courses are widely available today, with each one promising life-changing outcomes. Tim Han’s Life Mastery Achievers (LMA) Course has drawn a lot of interest. In addition to offering my frank assessment of Success Insider’s LMA Course, this piece examines the course’s effects via a variety of Tim Han LMA course reviews and Success Insider comments.
The French Revolution, which began in 1789, was a period of radical social and political upheaval in France. It marked the decline of absolute monarchies, the rise of secular and democratic republics, and the eventual rise of Napoleon Bonaparte. This revolutionary period is crucial in understanding the transition from feudalism to modernity in Europe.
For more information, visit-www.vavaclasses.com
2. • The conditions of pre-biotic Earth
• Experiments of Miller and Urey
• Hypothesis regarding first catalysts
• Theory that regarding RNA and replication
• Possible origin of membranes and prokaryotic
cells
• Endosymbiotic theory for the origin
of eukaryotes
MISS J WERBA – IB BIOLOGY 2
3.
4. D.1.1
• There are processes that were needed for the
spontaneous generation of life on Earth:
– Non-living synthesis of simple organic molecules
– Assembly of these molecules into polymers
– Inheritance possible once self-replicating
molecules originated
– Packaging of these molecules into membranes
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7. D.1.1
D.1.3
D.1.4
• 15 billion years after the “Big Bang”, the planets
began to form.
• The atmosphere on Earth at this time probably
contained a variety of inorganic molecules:
– Water vapour
– Methane
– Ammonia
– Hydrogen
– Carbon dioxide
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8. D.1.1
D.1.3
D.1.4
• The energy for forming the organic molecules was
provided by:
– frequent thunder storms and lightning strikes
– volcanic activity
– meteorite bombardment
– high temperatures due to
greenhouse gases
– UV radiation
(no ozone so was extreme)
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9. D.1.1
D.1.3
D.1.4
• These elements and inorganic molecules are
presumed to have been sufficient for life to begin.
• The organic molecules may have been generated on
Earth or introduced from space.
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10. D.1.1
D.1.3
D.1.4
• The hypothesis that life on Earth originated by
introduction of complex organic chemicals or even
bacteria via comets is called panspermia.
• A shower of comets about
4 thousand million years ago
could have introduced complex
organic molecules and water to
the Earth and initiated chemical
evolution.
MISS J WERBA – IB BIOLOGY 10
11.
12. D.1.1
• There was little to no oxygen in the atmosphere at
the time, as any oxygen was absorbed by rocks.
• This meant that there was no oxygen to steal
electrons away from other atoms (ie. oxidise them).
• This would have resulted in a ‘reducing atmosphere’
which would have made the joining of simple
molecules to form more complex ones more likely.
MISS J WERBA – IB BIOLOGY 12
13. D.1.1
• Experiments have shown that it is possible to form
organic molecules in a reducing atmosphere
• However it is very difficult to do when there is
oxygen in the atmosphere
• This polymerisation process would allow the larger
chemicals needed by cells to form.
MISS J WERBA – IB BIOLOGY 13
14. D.1.1
• How were polymers — the basis of life itself —
assembled????
• In solution, hydrolysis of a growing polymer would
soon limit the size it could reach.
• This has led to a theory that early polymers were
assembled on solid, mineral surfaces that protected
them from degradation.
• In lab experiments they have been synthesized on
clay.
MISS J WERBA – IB BIOLOGY 14
15.
16. D.1.1
D.1.5
• In current cells, DNA can replicate but it needs the
help of enzymes (proteins) to do this.
• The proteins are assembled based on information
carried on the DNA and transcribed into RNA.
• So what came first.....
the DNA to make proteins or
the proteins to make the DNA?!?!?!?!?
MISS J WERBA – IB BIOLOGY 16
17. D.1.1
D.1.5
• The synthesis of DNA and RNA requires proteins.
• So:
– proteins cannot be made without nucleic acids
and
– nucleic acids cannot be made without proteins
• Wrong!
MISS J WERBA – IB BIOLOGY 17
18. D.1.1
D.1.5
• The synthesis of nucleotides and their bases could
have happened easily.
• Once this had occurred, it is not hard to see how a
single strand of RNA could have formed.
• Once this had occurred, complementary base pairing
could have resulted in the non-enzymatic replication
of RNA.
MISS J WERBA – IB BIOLOGY 18
19. D.1.1
D.1.5
SOURCE: Purcell, D. (2009)
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20. D.1.1
D.1.5
• Self-replicating molecules are molecules that are
able to undergo replication.
• They are able to act as a template for copies of
themselves to be made.
• The only biological molecules capable of self-
replication are DNA & RNA.
• Unlike DNA, RNA sequences are capable of self-
replication: it can catalyse its formation from
nucleotides in the absence of proteins.
MISS J WERBA – IB BIOLOGY 20
21. D.1.1
D.1.5
SOURCE: Purcell, D. (2009)
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22. D.1.1
D.1.5
• The discovery that certain RNA molecules have
enzymatic activity provides a possible solution.
• These RNA molecules — called ribozymes—
incorporate both the features required of life:
– storage of information
– the ability to act as catalysts
• Active ribozymes can be easily assembled from
shorter olignonucleotides (strands of nucleotides).
MISS J WERBA – IB BIOLOGY 22
23. D.1.1
D.1.5
• Ribozymes have been synthesized in the laboratory
and can catalyze exact complements of themselves.
• The ribozyme serves as both:
– the template on which short lengths of RNA
("oligonucleotides“) are assembled, following the
rules of base pairing and
– the catalyst for covalently linking these
oligonucleotides.
MISS J WERBA – IB BIOLOGY 23
24. D.1.1
D.1.5
SOURCE: Purcell, D. (2009)
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25. D.1.1
D.1.5
• Evidence for this ideas is provided by the fact that
many of the cofactors that play so many roles in life
are based on ribose:
ATP
NAD
FAD
coenzyme A
cyclic AMP
GTP
MISS J WERBA – IB BIOLOGY 25
26.
27. D.1.1
D.1.6
• The development of the lipid bilayer was imitated in
the laboratory by Fox and his co-workers
• They heated amino acids without water and
produced long protein chains
• When water was added and
the mixture cooled, small
stable microspheres or
coacervates were formed
MISS J WERBA – IB BIOLOGY 27
28. D.1.1
D.1.6
• The coacervates seemed to be able to accumulate
certain compounds inside them so that they became
more concentrated than outside
• They also attracted lipids and
formed a lipid-protein layer
around them
MISS J WERBA – IB BIOLOGY 28
29. D.1.1
D.1.6
• If we assume that the coacervates also combined
with self-replicating molecules such as RNA, we are
looking at a very primitive organism...
• This is thought to have happened about 3.8 billion
years ago
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30. D.1.1
D.1.6
SOURCE: Purcell, D. (2009)
MISS J WERBA – IB BIOLOGY 30
31. D.1.1
D.1.6
SOURCE: Purcell, D. (2009)
MISS J WERBA – IB BIOLOGY 31
32. D.1.1
D.1.6
• The aggregates or coacervates are also known as
protobionts or proto cells.
• The most successful liposomes (protobiont in
presence of lipids) at surviving would have passed on
their characteristics and developed into early
prokaryotes!
MISS J WERBA – IB BIOLOGY 32
33. D.1.1
D.1.6
SOURCE: McFadden, G. (2009)
MISS J WERBA – IB BIOLOGY 33
34. D.1.1
D.1.6
SOURCE: McFadden, G. (2009)
MISS J WERBA – IB BIOLOGY 34
35.
36. D.1.2
• Stanley Miller and Harold Urey worked on trying to
confirm some of these ideas regarding pre-biotic
Earth.
• In 1953, Miller set up an apparatus to simulate
conditions on the early Earth.
• The apparatus contained a warmed flask of water
simulating the primeval sea and an atmosphere of
water, hydrogen gas, CH4 (methane), and NH3
(ammonia).
MISS J WERBA – IB BIOLOGY 36
38. D.1.2
• Sparks were discharged in the synthetic atmosphere
to mimic lightning.
• Water was boiled, while a condenser cooled the
atmosphere, raining water and any dissolved
compounds back to the miniature sea.
• The simulated environment produced many types of
amino acids and other organic molecules leading
them to conclude the pre-biotic synthesis of organic
molecules was possible.
MISS J WERBA – IB BIOLOGY 38
40. D.1.2
• This spontaneous generation of organic molecules
was supported by investigation of meteorites.
• In 1970, a meteorite was found
to contain 7 different amino
acids, 2 of which are not found
in living things on Earth.
MISS J WERBA – IB BIOLOGY 40
43. D.1.7
SOURCE: McFadden, G. (2009)
MISS J WERBA – IB BIOLOGY 43
44. D.1.7
• Prokaryotes had the planet to themselves for about 2
billion years!
• Oxygen began to gradually accumulate in the
atmosphere on Earth.
• Bacteria evolved naturally to contain a form of
chlorophyll, which then allowed a simple form of
photosynthesis to occur.
MISS J WERBA – IB BIOLOGY 44
45. D.1.7
• This caused an explosive rise in the levels of
atmospheric oxygen known as the oxygen
catastrophe.
• This had an irreversible effect on the subsequent
evolution of life.
• The remaining chemicals in the “chemical soup” in
the oceans were broken down into carbon dioxide
and oxidised sediments.
MISS J WERBA – IB BIOLOGY 45
46. D.1.7
• In addition, a layer of ozone (O3) began to form in
the upper atmosphere.
• This protected the planet
from UV radiation from
the Sun and blocked the
production of new organic
chemicals in the
“chemical soup”.
MISS J WERBA – IB BIOLOGY 46
47.
48. D.1.8
SOURCE: McFadden, G. (2009)
MISS J WERBA – IB BIOLOGY 48
49. D.1.8
SOURCE: McFadden, G. (2009)
MISS J WERBA – IB BIOLOGY 49
50. D.1.8
SOURCE: McFadden, G. (2009)
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51. D.1.8
• Grypania is ~2mm in diameter, so it is too big to be a
prokaryotic cell.
• Tappania is definitely too big and complicated to be
prokaryotic.
• Bangiomorpha had 3D structure! Definitely too
complicated to be prokaryotic!
MISS J WERBA – IB BIOLOGY 51
52. D.1.8
• The oldest fossils of eukaryotic cells have been found
to be approximately 1.5 billion years old.
• The endosymbiotic theory from Lyn Margulis (1967)
tries to explain how eukaryotic cells may have
evolved.
• Endosymbiosis: the condition in which one organism
lives inside the cell of another organism
• Both cells benefit from this - the cells no longer can
live separately from each other
MISS J WERBA – IB BIOLOGY 52
54. D.1.8
• Mitochondria and chloroplasts were once free living
bacteria cells:
– Mitochondria aerobic bacteria
– Chloroplasts photosynthetic bacteria
• These cells were “swallowed up” by other cells by
endocytosis cells engulfed but not eaten
MISS J WERBA – IB BIOLOGY 54
57. D.1.8
• Mitochondria:
– additional energy (aerobic respiration) and
receives protection
• Chloroplast:
– provide food by photosynthesis and receives
protection
MISS J WERBA – IB BIOLOGY 57
58. D.1.8
• Prokaryotes are similar to mitochondria and
chloroplasts:
– Similar size
– Similar ribosomes (70S)
– Contain DNA that is different from the nucleus
– Surrounded by double membrane
– Formation of new organelles resembles binary
fission
MISS J WERBA – IB BIOLOGY 58
59. D.1.8
• The four eukaryotic kingdoms are:
– Protoctista
– Fungi
– Plantae
– Animalia
• Eukaryotic cells have some advantages over
prokaryotic cells so the early eukaryotes survived
and proliferated
• Hence the wide diversity of species we know today!
MISS J WERBA – IB BIOLOGY 59