Colles' fracture is a fracture of the distal radius near the wrist. It often results in dorsal displacement of the distal fragment and occurs most commonly in women over 40 from falls on an outstretched hand. Clinical features include pain, swelling, and the classic "dinner fork deformity". Treatment depends on the degree of displacement, with undisplaced fractures treated conservatively in a cast and displaced fractures requiring manipulative closed reduction and casting or open surgical fixation with plates. Complications can include joint stiffness, malunion, subluxation, and nerve damage if not properly treated.
Ganglion cysts are small, mucus-filled cysts that commonly occur on the back of the wrist. They can also develop on other joints like fingers, knees, and ankles. Ganglion cysts are usually painless bumps but can become painful with activity. Ultrasound or MRI can confirm the cystic nature of the bump. Treatment involves initial aspiration and steroid injection for small cysts. Larger or recurring cysts may require surgical excision to prevent reoccurrence.
Carpal tunnel syndrome involves pressure on the median nerve as it passes through the carpal tunnel in the wrist. Common symptoms include numbness, tingling, and weakness in the hand and fingers. The cause is often unknown but may involve repetitive wrist motions, swelling from conditions like arthritis or pregnancy, or certain anatomical factors. Diagnosis involves physical exams like Tinel's sign and Phalen's maneuver as well as nerve conduction studies or EMG tests. Treatment ranges from splinting, anti-inflammatory drugs, corticosteroid injections, surgery to release pressure on the nerve. Rehabilitation after surgery focuses on scar tissue massage, modalities to reduce pain and swelling, and exercises to strengthen the hand muscles and improve function.
This document provides guidance on examining swellings and lumps. It describes the key steps and characteristics to assess when examining a swelling. The examiner should first inspect the swelling to note its position and any abnormalities of the overlying skin. They then perform initial palpation to check for pulsation and tenderness. Further detailed palpation allows assessment of mobility, shape, surface, edge, consistency, ability to indent, fluctuation, temperature and size. Transillumination may also be attempted. A thorough swelling examination provides important clinical information to help determine the underlying cause.
This document presents a case study of a 56-year-old man with type 2 diabetes presenting with a non-healing ulcer on his right foot following toe amputation. It provides details of his medical history, examination findings, lab investigations, and discusses diabetic foot ulcers and complications. The key points are:
1) The patient had type 2 diabetes for 10 years and was non-compliant with medication, presenting with a non-healing ulcer on his right foot post amputation of toes.
2) Examination found an irregular ulcer on his right foot with signs of infection. Investigations showed renal dysfunction and hyperglycemia.
3) Diabetic foot ulcers are a major complication
Colles' fracture is a fracture of the distal radius near the wrist. It often results in dorsal displacement of the distal fragment and occurs most commonly in women over 40 from falls on an outstretched hand. Clinical features include pain, swelling, and the classic "dinner fork deformity". Treatment depends on the degree of displacement, with undisplaced fractures treated conservatively in a cast and displaced fractures requiring manipulative closed reduction and casting or open surgical fixation with plates. Complications can include joint stiffness, malunion, subluxation, and nerve damage if not properly treated.
Ganglion cysts are small, mucus-filled cysts that commonly occur on the back of the wrist. They can also develop on other joints like fingers, knees, and ankles. Ganglion cysts are usually painless bumps but can become painful with activity. Ultrasound or MRI can confirm the cystic nature of the bump. Treatment involves initial aspiration and steroid injection for small cysts. Larger or recurring cysts may require surgical excision to prevent reoccurrence.
Carpal tunnel syndrome involves pressure on the median nerve as it passes through the carpal tunnel in the wrist. Common symptoms include numbness, tingling, and weakness in the hand and fingers. The cause is often unknown but may involve repetitive wrist motions, swelling from conditions like arthritis or pregnancy, or certain anatomical factors. Diagnosis involves physical exams like Tinel's sign and Phalen's maneuver as well as nerve conduction studies or EMG tests. Treatment ranges from splinting, anti-inflammatory drugs, corticosteroid injections, surgery to release pressure on the nerve. Rehabilitation after surgery focuses on scar tissue massage, modalities to reduce pain and swelling, and exercises to strengthen the hand muscles and improve function.
This document provides guidance on examining swellings and lumps. It describes the key steps and characteristics to assess when examining a swelling. The examiner should first inspect the swelling to note its position and any abnormalities of the overlying skin. They then perform initial palpation to check for pulsation and tenderness. Further detailed palpation allows assessment of mobility, shape, surface, edge, consistency, ability to indent, fluctuation, temperature and size. Transillumination may also be attempted. A thorough swelling examination provides important clinical information to help determine the underlying cause.
This document presents a case study of a 56-year-old man with type 2 diabetes presenting with a non-healing ulcer on his right foot following toe amputation. It provides details of his medical history, examination findings, lab investigations, and discusses diabetic foot ulcers and complications. The key points are:
1) The patient had type 2 diabetes for 10 years and was non-compliant with medication, presenting with a non-healing ulcer on his right foot post amputation of toes.
2) Examination found an irregular ulcer on his right foot with signs of infection. Investigations showed renal dysfunction and hyperglycemia.
3) Diabetic foot ulcers are a major complication
Fat embolism syndrome is caused by fat globules entering the bloodstream after trauma like long bone fractures. It can cause respiratory failure, neurological symptoms, and a rash. Diagnosis is based on clinical criteria like hypoxemia, thrombocytopenia, and petechial rash appearing 1-4 days after injury. Treatment focuses on respiratory support, fluid resuscitation, steroids to reduce lung inflammation, and early fracture fixation to prevent worsening.
Sebaceous cysts are caused by blockage of the duct of the sebaceous gland, causing the gland to become distended by its own secretion of sebum. Clinically, sebaceous cysts present as movable, non-tender swellings under the skin, often with a visible punctum or opening. They are diagnosed through examination finding fluctuation and transillumination negativity. Treatment involves surgical removal by incising the cyst and expressing its contents. Complications can arise if the cyst becomes infected or ruptured.
This document discusses nerve injury classification and techniques for nerve regeneration and repair. It describes two main classification systems - Seddon from 1943 and Sunderland from 1951. Seddon classified injuries as neuroprexia, axonotmesis, or neurotmesis. Sunderland's more detailed system classified injuries from 1st to 5th degree based on the anatomical structures disrupted. The document also discusses nerve degeneration, regeneration, diagnostic tests like nerve conduction studies and EMG, and techniques for nerve repair including neurolysis, neurorrhaphy, and nerve grafting.
The document discusses the definition and types of pain. It defines pain as an unpleasant sensory and emotional experience arising from actual or potential tissue damage. It describes four main types of pain: superficial, segmental, deep, and psychogenic. The document emphasizes the importance of a thorough pain history in order to make an accurate diagnosis. It provides a list of key factors to assess in a pain history, including location, onset, severity, nature, progression, duration, aggravating/relieving factors, and any associated symptoms. Assessing these factors can provide clues to determine the underlying cause of a patient's pain.
This document discusses principles of fracture management. It defines fractures and classifies them as closed or open. The main types of fractures are due to injury, repetitive stress, or pathological weakening of bone. Clinical diagnosis involves history, symptoms, and radiography. Fractures are classified based on location, stability, direction, and mechanism of injury. Treatment depends on if the fracture is closed or open. Closed fractures are typically treated conservatively with splinting, casting, or traction, or surgically with internal or external fixation. Open fractures require urgent debridement, antibiotics, stabilization, and wound coverage.
Osteomyelitis is an infection of bone and bone marrow that was coined in 1834 and refers to inflammation of bone. It can remain localized or spread through the bone. It is classified based on duration as acute, subacute, or chronic, and based on mechanism as hematogenous, exogenous, or by host response. Common causes are trauma, prosthetic devices, and immunocompromised states. Symptoms include fever, pain, and swelling. Diagnosis involves aspirating pus, blood tests, and imaging like x-ray, CT, or MRI. Treatment is based on antibiotics and possible surgery to debride infected tissue. Complications can include chronic infection, septic arthritis, and pathological fractures if not
This document discusses ulcers, including their definition, parts, classifications, investigations, and management. It defines an ulcer as a break in the skin or mucous membrane epithelium due to cell death. The key parts of an ulcer are the margin, edge, floor, and base. Ulcers can be classified clinically based on healing status, duration, or etiology. Investigations may include wound cultures, biopsies, and imaging. Management involves treating the underlying cause, wound cleaning, debridement, dressings, and therapies like vacuum-assisted closure or maggot debridement to promote healing.
This document discusses the surgical management of inguinal hernias. It defines a hernia and describes the different types, including inguinal hernias. It discusses the anatomy of the inguinal canal and its contents. The document outlines both open and laparoscopic surgical repair techniques for inguinal hernias, including the Bassini repair, Shouldice repair, tension-free mesh repairs, and laparoscopic total extraperitoneal (TEP) and transabdominal preperitoneal (TAPP) approaches. It compares the advantages and disadvantages of open versus laparoscopic techniques.
Osteomyelitis is an inflammation of bone caused by bacterial infection. It can be acute (<2 weeks), subacute (2-6 weeks), or chronic (>6 weeks) depending on duration and symptoms. Common causative organisms are Staphylococcus aureus and other staph species. In children, S. aureus and group B streptococcus are frequent causes. Chronic osteomyelitis is characterized by necrotic bone (sequestrum) surrounded by inflammatory tissue (involucrum). Symptoms include pain, swelling, and draining sinuses. The metaphysis of long bones is a common site due to its vascular anatomy.
This document outlines the principles of amputation, including definitions, indications, types, pre-operative evaluation, operative techniques, post-operative care, and complications. It notes that amputation is an ancient procedure that should be viewed not as a failure of treatment, but as the first step towards allowing a patient to return to a more comfortable life. The document emphasizes the multidisciplinary nature of amputation and importance of both surgical and post-operative care in achieving the best outcomes for patients.
a basic and concise description of one of the most common clinical condition we encounter in our daily practice. this info has been gathered from several sources. feel free to point out any mistakes. :)
Examination of Swelling in a patient is always a task for MBBS students. This PPT provides the students, how to elicit a history & also the easy way to examine a swelling.
This document discusses osteomyelitis, an infection and inflammation of bone and bone marrow. It describes the different types of osteomyelitis, including pyogenic (bacterial), tuberculous, and syphilitic osteomyelitis. The stages and morphology of osteomyelitis are outlined from the acute stage of bacterial proliferation to the chronic stage involving bone necrosis, abscess formation, and new bone growth. Clinical manifestations, laboratory diagnosis, and radiological findings are also summarized.
The document defines fractures, dislocations, and subluxations as breaks or displacements in bones. It then discusses classifying fractures to guide treatment, prognosis, and common terminology. Fractures are classified based on their relationship to the environment (closed vs open), degree of displacement, fracture pattern (transverse, oblique, etc.), etiology (traumatic vs pathological), and location. Signs of fractures include swelling, pain, numbness, bleeding, and limited movement. The document also discusses dislocations as complete displacements of joints and subluxations as incomplete displacements.
Diabetic foot complications are a major cause of lower limb amputations. Factors like neuropathy, vasculopathy and immune dysfunction contribute to foot ulceration and infection in diabetes. Ulcers are classified based on etiology and severity. Management involves metabolic control, wound care, offloading, antibiotics, vascular assessment and revascularization if needed. Long term prevention relies on regular foot screening, education on foot care, appropriate footwear and multidisciplinary team approach.
The document discusses various pathologies that can occur with fractures beyond just the bone break itself. It classifies complications as immediate, early, or late and discusses specific issues like hypovolamic shock, fat embolism, deep vein thrombosis, crush syndrome, compartment syndrome, and delayed or non-union. Treatment options are provided for many of these complications aiming to address the underlying causes and minimize long-term disabilities. Early diagnosis and aggressive management of fractures and their associated issues is emphasized.
This document outlines principles of amputation, beginning with definitions and a brief history. It discusses indications for amputation including the 3 D's (dead, dying, or damn nuisance limb) and covers pre-operative, intra-operative, and post-operative principles and considerations. Complications are addressed as well as amputation in children. Prosthetics and rehabilitation goals are also summarized. The document provides an overview of best practices and factors to consider for successful amputation outcomes.
1. The document discusses the metabolic response to injury, which involves complex physiological and hormonal changes aimed at restoring homeostasis following trauma.
2. It describes the phases of the metabolic response as including an initial "ebb" phase aimed at conserving energy, followed by a "flow" or catabolic phase involving increased metabolism and breakdown of proteins and fat to mobilize energy stores.
3. Key elements of the catabolic flow phase include hypermetabolism, increased protein breakdown in skeletal muscle and liver, insulin resistance, and changes in body composition with loss of muscle mass. Mediators include stress hormones and cytokines.
Mr. Y, a 20-year-old male, presented with sudden sharp abdominal pain on the right lower quadrant for several hours. His symptoms included vomiting and a high pain rating. On examination, he had guarding and tenderness in the right lower quadrant. Tests showed an elevated white blood cell count. He was diagnosed with acute appendicitis and underwent an open appendectomy. During surgery, his appendix was found to be inflamed. He was treated post-operatively with antibiotics and pain medication.
Clubbing, also known as Hippocrates fingers, is the bulbous enlargement of the fingertips and nails. It is caused by proliferation of subcutaneous tissues due to chronic hypoxemia from conditions like lung diseases, heart diseases, and liver or gastrointestinal diseases. Examination involves comparing the fingernails to look for reduced or absent diamond-shaped spaces, indicating clubbing. While clubbing itself has no treatment, addressing the underlying condition can potentially reverse it over time.
1) Factors like age, type of trauma, position of the mandible during impact, force and angle of impact determine the degree of laryngotracheal trauma.
2) Symptoms vary and include respiratory distress, voice changes, pain with swallowing or speaking, and hemoptysis. External signs include bruising, swelling, subcutaneous emphysema, and deformities of the larynx.
3) Investigations include laryngoscopy, CT scan, and x-rays which can reveal injuries to laryngeal structures and cartilages as well as fractures.
Fat embolism syndrome is caused by fat globules entering the bloodstream after trauma like long bone fractures. It can cause respiratory failure, neurological symptoms, and a rash. Diagnosis is based on clinical criteria like hypoxemia, thrombocytopenia, and petechial rash appearing 1-4 days after injury. Treatment focuses on respiratory support, fluid resuscitation, steroids to reduce lung inflammation, and early fracture fixation to prevent worsening.
Sebaceous cysts are caused by blockage of the duct of the sebaceous gland, causing the gland to become distended by its own secretion of sebum. Clinically, sebaceous cysts present as movable, non-tender swellings under the skin, often with a visible punctum or opening. They are diagnosed through examination finding fluctuation and transillumination negativity. Treatment involves surgical removal by incising the cyst and expressing its contents. Complications can arise if the cyst becomes infected or ruptured.
This document discusses nerve injury classification and techniques for nerve regeneration and repair. It describes two main classification systems - Seddon from 1943 and Sunderland from 1951. Seddon classified injuries as neuroprexia, axonotmesis, or neurotmesis. Sunderland's more detailed system classified injuries from 1st to 5th degree based on the anatomical structures disrupted. The document also discusses nerve degeneration, regeneration, diagnostic tests like nerve conduction studies and EMG, and techniques for nerve repair including neurolysis, neurorrhaphy, and nerve grafting.
The document discusses the definition and types of pain. It defines pain as an unpleasant sensory and emotional experience arising from actual or potential tissue damage. It describes four main types of pain: superficial, segmental, deep, and psychogenic. The document emphasizes the importance of a thorough pain history in order to make an accurate diagnosis. It provides a list of key factors to assess in a pain history, including location, onset, severity, nature, progression, duration, aggravating/relieving factors, and any associated symptoms. Assessing these factors can provide clues to determine the underlying cause of a patient's pain.
This document discusses principles of fracture management. It defines fractures and classifies them as closed or open. The main types of fractures are due to injury, repetitive stress, or pathological weakening of bone. Clinical diagnosis involves history, symptoms, and radiography. Fractures are classified based on location, stability, direction, and mechanism of injury. Treatment depends on if the fracture is closed or open. Closed fractures are typically treated conservatively with splinting, casting, or traction, or surgically with internal or external fixation. Open fractures require urgent debridement, antibiotics, stabilization, and wound coverage.
Osteomyelitis is an infection of bone and bone marrow that was coined in 1834 and refers to inflammation of bone. It can remain localized or spread through the bone. It is classified based on duration as acute, subacute, or chronic, and based on mechanism as hematogenous, exogenous, or by host response. Common causes are trauma, prosthetic devices, and immunocompromised states. Symptoms include fever, pain, and swelling. Diagnosis involves aspirating pus, blood tests, and imaging like x-ray, CT, or MRI. Treatment is based on antibiotics and possible surgery to debride infected tissue. Complications can include chronic infection, septic arthritis, and pathological fractures if not
This document discusses ulcers, including their definition, parts, classifications, investigations, and management. It defines an ulcer as a break in the skin or mucous membrane epithelium due to cell death. The key parts of an ulcer are the margin, edge, floor, and base. Ulcers can be classified clinically based on healing status, duration, or etiology. Investigations may include wound cultures, biopsies, and imaging. Management involves treating the underlying cause, wound cleaning, debridement, dressings, and therapies like vacuum-assisted closure or maggot debridement to promote healing.
This document discusses the surgical management of inguinal hernias. It defines a hernia and describes the different types, including inguinal hernias. It discusses the anatomy of the inguinal canal and its contents. The document outlines both open and laparoscopic surgical repair techniques for inguinal hernias, including the Bassini repair, Shouldice repair, tension-free mesh repairs, and laparoscopic total extraperitoneal (TEP) and transabdominal preperitoneal (TAPP) approaches. It compares the advantages and disadvantages of open versus laparoscopic techniques.
Osteomyelitis is an inflammation of bone caused by bacterial infection. It can be acute (<2 weeks), subacute (2-6 weeks), or chronic (>6 weeks) depending on duration and symptoms. Common causative organisms are Staphylococcus aureus and other staph species. In children, S. aureus and group B streptococcus are frequent causes. Chronic osteomyelitis is characterized by necrotic bone (sequestrum) surrounded by inflammatory tissue (involucrum). Symptoms include pain, swelling, and draining sinuses. The metaphysis of long bones is a common site due to its vascular anatomy.
This document outlines the principles of amputation, including definitions, indications, types, pre-operative evaluation, operative techniques, post-operative care, and complications. It notes that amputation is an ancient procedure that should be viewed not as a failure of treatment, but as the first step towards allowing a patient to return to a more comfortable life. The document emphasizes the multidisciplinary nature of amputation and importance of both surgical and post-operative care in achieving the best outcomes for patients.
a basic and concise description of one of the most common clinical condition we encounter in our daily practice. this info has been gathered from several sources. feel free to point out any mistakes. :)
Examination of Swelling in a patient is always a task for MBBS students. This PPT provides the students, how to elicit a history & also the easy way to examine a swelling.
This document discusses osteomyelitis, an infection and inflammation of bone and bone marrow. It describes the different types of osteomyelitis, including pyogenic (bacterial), tuberculous, and syphilitic osteomyelitis. The stages and morphology of osteomyelitis are outlined from the acute stage of bacterial proliferation to the chronic stage involving bone necrosis, abscess formation, and new bone growth. Clinical manifestations, laboratory diagnosis, and radiological findings are also summarized.
The document defines fractures, dislocations, and subluxations as breaks or displacements in bones. It then discusses classifying fractures to guide treatment, prognosis, and common terminology. Fractures are classified based on their relationship to the environment (closed vs open), degree of displacement, fracture pattern (transverse, oblique, etc.), etiology (traumatic vs pathological), and location. Signs of fractures include swelling, pain, numbness, bleeding, and limited movement. The document also discusses dislocations as complete displacements of joints and subluxations as incomplete displacements.
Diabetic foot complications are a major cause of lower limb amputations. Factors like neuropathy, vasculopathy and immune dysfunction contribute to foot ulceration and infection in diabetes. Ulcers are classified based on etiology and severity. Management involves metabolic control, wound care, offloading, antibiotics, vascular assessment and revascularization if needed. Long term prevention relies on regular foot screening, education on foot care, appropriate footwear and multidisciplinary team approach.
The document discusses various pathologies that can occur with fractures beyond just the bone break itself. It classifies complications as immediate, early, or late and discusses specific issues like hypovolamic shock, fat embolism, deep vein thrombosis, crush syndrome, compartment syndrome, and delayed or non-union. Treatment options are provided for many of these complications aiming to address the underlying causes and minimize long-term disabilities. Early diagnosis and aggressive management of fractures and their associated issues is emphasized.
This document outlines principles of amputation, beginning with definitions and a brief history. It discusses indications for amputation including the 3 D's (dead, dying, or damn nuisance limb) and covers pre-operative, intra-operative, and post-operative principles and considerations. Complications are addressed as well as amputation in children. Prosthetics and rehabilitation goals are also summarized. The document provides an overview of best practices and factors to consider for successful amputation outcomes.
1. The document discusses the metabolic response to injury, which involves complex physiological and hormonal changes aimed at restoring homeostasis following trauma.
2. It describes the phases of the metabolic response as including an initial "ebb" phase aimed at conserving energy, followed by a "flow" or catabolic phase involving increased metabolism and breakdown of proteins and fat to mobilize energy stores.
3. Key elements of the catabolic flow phase include hypermetabolism, increased protein breakdown in skeletal muscle and liver, insulin resistance, and changes in body composition with loss of muscle mass. Mediators include stress hormones and cytokines.
Mr. Y, a 20-year-old male, presented with sudden sharp abdominal pain on the right lower quadrant for several hours. His symptoms included vomiting and a high pain rating. On examination, he had guarding and tenderness in the right lower quadrant. Tests showed an elevated white blood cell count. He was diagnosed with acute appendicitis and underwent an open appendectomy. During surgery, his appendix was found to be inflamed. He was treated post-operatively with antibiotics and pain medication.
Clubbing, also known as Hippocrates fingers, is the bulbous enlargement of the fingertips and nails. It is caused by proliferation of subcutaneous tissues due to chronic hypoxemia from conditions like lung diseases, heart diseases, and liver or gastrointestinal diseases. Examination involves comparing the fingernails to look for reduced or absent diamond-shaped spaces, indicating clubbing. While clubbing itself has no treatment, addressing the underlying condition can potentially reverse it over time.
1) Factors like age, type of trauma, position of the mandible during impact, force and angle of impact determine the degree of laryngotracheal trauma.
2) Symptoms vary and include respiratory distress, voice changes, pain with swallowing or speaking, and hemoptysis. External signs include bruising, swelling, subcutaneous emphysema, and deformities of the larynx.
3) Investigations include laryngoscopy, CT scan, and x-rays which can reveal injuries to laryngeal structures and cartilages as well as fractures.
The document discusses crush injuries to the hand, including:
- The anatomy of the hand and the tissues that can be damaged in a crush injury.
- Common causes of crush injuries like machinery, accidents, and collapsed buildings.
- Signs and symptoms include bleeding, fractures, pain and loss of mobility.
- Treatment depends on severity but involves wound care, splinting, and possibly surgery to repair damaged tissues.
- Complications can include infection, impaired mobility, and systemic issues if crushing persists for over 4 hours.
The document discusses various soft tissue disorders classified under code M70-M79 in ICD-10-CM. It defines bursitis as inflammation of the bursa sacs located around muscles and bones commonly in the shoulder, elbow, wrist, hip, knee, or ankle. Bursopathies refer to diseases of the bursa sacs which can include bursitis. A synovial cyst in the popliteal space behind the knee can cause knee stiffness and pain. Infective bursitis results from bacterial infection entering the bursa. Bicipital tendinitis is inflammation of the bicep tendon in the shoulder. Enthesopathies involve disorders at the attachment points of
1. Trauma can cause various injuries to the skin and tissues including abrasions, avulsions, bruises, lacerations, and puncture wounds. Gunshot wounds require cleaning of the entry and exit wounds and prevention of further contamination.
2. The primary survey in trauma management focuses on assessing and ensuring the airway, breathing, and circulation of the patient while also identifying life-threatening injuries. Intubation or tracheostomy may be needed to secure the airway. Chest tubes can be inserted to drain blood or air from a hemopneumothorax.
3. Different types of burns require specific treatments. Chemical burns require decontamination while electrical burns require identifying the power source. Burns
Dr. Binaya kumar Padhi presented on decubitus ulcers (pressure sores). He defined decubitus ulcers as traumatic ulcers caused by direct pressure or shearing forces on bony tissues, leading to tissue necrosis and ulceration. Risk factors include immobility, malnutrition, and spinal cord injury. Prevention focuses on frequent repositioning to reduce pressure, maintaining good nutrition, and early mobilization. Treatment involves wound cleaning, debridement of necrotic tissue, dressing changes, and sometimes flaps or skin grafts. Managing underlying risks and recurrent pressure is important for healing.
This document discusses necrotizing soft tissue infections (NSTI), including anatomy, risk factors, diagnosis, treatment, and references. It describes how NSTI rapidly progress through fascial planes, causing tissue necrosis. Diagnosis involves clinical signs, lab tests like LRINEC scoring, and imaging like CT/MRI showing fascial inflammation and gas. Treatment requires urgent wide surgical debridement, broad-spectrum antibiotics, resuscitation, and possible adjuncts like hyperbaric oxygen or IV immunoglobulin.
Osteoarthritis is a type of joint disease involving breakdown of cartilage and underlying bone. It most commonly affects the hands, hips, knees, and spine. Risk factors include age, genetics, injury, and overweight. Symptoms include joint pain and stiffness. Treatment involves medications like NSAIDs, exercise, weight loss, and sometimes surgery.
Rheumatoid arthritis is an autoimmune disease causing chronic inflammation of joints and tissues. It commonly affects the wrists, fingers, and feet. Pathology involves synovial inflammation and destruction of cartilage and bone. Symptoms include symmetric joint pain and swelling. Diagnosis is based on symptoms and serological testing. Treatment focuses on reducing inflammation and pain through medications, exercise, and
The document discusses crush injuries to the hand, describing the anatomy of the hand, tendons, and zones of injury. It outlines the mechanisms, signs and symptoms, complications, management, and nursing care for crush injuries. Prevention strategies and specific injuries like Jersey finger and trigger finger are also reviewed.
This document discusses complications that can arise from fractures, including general complications affecting the whole body and local complications affecting the site of the fracture. Some early local complications mentioned are visceral injury, vascular injury, nerve injury, compartment syndrome, and infection such as gas gangrene. Late local complications include delayed union, non-union, and malunion of the fractured bone. The document then goes on to provide more details on specific early local complications such as types of vascular and nerve injuries that can occur with different fracture locations. Treatment approaches for various complications like vascular injury, nerve injury, compartment syndrome, and gas gangrene infections are also summarized.
This document discusses complications that can arise from fractures, including general complications affecting the whole body and local complications affecting the site of the fracture. Some early local complications mentioned are visceral injury, vascular injury, nerve injury, compartment syndrome, and infection such as gas gangrene. Late local complications include delayed union, non-union, and malunion of the fractured bone. The document then goes on to provide more details on specific early local complications such as types of vascular and nerve injuries that can occur with different fracture locations. Treatment approaches for certain complications like vascular injury, compartment syndrome, and gas gangrene infections are also summarized.
This document provides an overview of general anatomy, including its history and subdivisions. It discusses key figures in the history of anatomy such as Hippocrates, Herophilus, Leonardo da Vinci, and Vesalius. The subdivisions of anatomy covered include regional anatomy, systemic anatomy, embryology, histology, and others. Common anatomical terminology is defined, including terms used to describe positions, planes, muscles, bones, and clinical anatomy.
Tuberculous tenosynovitis, or tuberculosis of the tendon sheaths, is a rare form of extrapulmonary tuberculosis that can lead to complications if not properly diagnosed and treated. It occurs when tuberculosis bacteria infect the synovial sheaths surrounding tendons. On histopathological examination, rice bodies may be seen within the synovial fluid. Treatment involves immobilizing the affected area, administering antitubercular drugs for 9-12 months, and potentially surgical debridement if symptoms persist or worsen. Early diagnosis and treatment can prevent joint destruction and recurrence of symptoms.
1. The thorax contains important structures like the lungs, heart, blood vessels, and nerves. Common clinical issues involving the thorax include cervical ribs pressing on nerves or arteries, rib fractures from blunt trauma, and flail chest from multiple rib fractures.
2. Surgical procedures on the thorax often require incisions between the ribs or removal of portions of ribs to access the organs within. The sternum and costal cartilages are also clinically relevant for biopsies, fractures, and dividing (median sternotomy) during heart surgery.
3. Thoracic outlet syndromes can occur when nerves or blood vessels passing from the thorax into the upper limbs become compressed, such as between the clavicle
This document provides information about osteoarthritis, including its definition, statistics, demographics, anatomy, causes, risk factors, pathophysiology, diagnosis, treatment and management. Some key points:
- OA is a joint disease caused by breakdown of cartilage and underlying bone, leading to joint pain, swelling and decreased mobility. It most commonly affects weight-bearing joints like the knee and hip.
- It is estimated that 251 million people worldwide suffer from knee OA. It is the second greatest cause of disability globally.
- Risk factors include age, gender, genetics, obesity, trauma and occupation. Treatment focuses on pain management, slowing progression, and improving function through medications, injections, exercise and sometimes surgery
5 Ischemia Infarction & Gangrene in pathology.pptxssuser9976be
Dry gangrene is caused by arterial occlusion alone, resulting in slow putrefaction and spread. It can cause natural amputation. Wet gangrene involves both arterial and venous occlusion, leading to rapid putrefaction and spread. No line of demarcation forms and toxemia is often fatal. Gas gangrene occurs when deep wounds are contaminated by Clostridium bacteria, causing muscle necrosis, gas formation and severe toxemia.
Cartilage is a connective tissue found in joints between bones. It is made up of cells called chondrocytes that produce collagen, proteoglycans, and elastin. There are no blood vessels in cartilage, so it repairs and grows slowly. Tendons connect muscle to bone and are made of collagen, while ligaments connect bones to other bones. Joints are points where bones connect, allowing movement, and can be classified by the tissue present and degree of movement. Common joint disorders include dislocations, sprains, bursitis, and various forms of arthritis.
AMPUTATION: Cutting of the extremity or part of the extremity through the bone
While ………..
DISARTICULATION: Cutting of the extremity or part of the extremity through the joint
Lung cancer is potentially fatal for dogs and can be devastating for owners. There are two types - primary lung cancer originating in the lung tissue, and metastatic lung cancer spreading from other areas. Primary lung cancer presents as a large solitary mass, while metastatic cancers are usually multiple masses. Diagnosis involves chest x-rays, CT/MRI, biopsy. Single masses can often be surgically removed through a lateral thoracotomy procedure, while multiple masses are usually treated with chemotherapy as cancer has spread. Prognosis is generally good for dogs with completely resected primary lung tumors.
This document summarizes thalassemia, a hereditary blood disorder caused by reduced or absent production of hemoglobin A. It describes the main types (alpha and beta thalassemia), clinical features like anemia and jaundice, diagnostic testing, and management which includes lifelong blood transfusions and iron chelation therapy to prevent complications from iron overload. The most severe forms can be fatal without treatment while milder forms may cause few symptoms.
Suffocation is a general term used to indicate death due to lack of oxygen from either lack of oxygen in the breathable environment or obstruction of external air passages. Asphyxia is caused by lack of oxygen in respired air leading to hypoxaemia and hypercapnia. Smothering causes asphyxia through mechanical obstruction of the external airways (nose and mouth). Suicidal smothering often involves placing a plastic bag over the head in an attempt to cut off oxygen. Classic signs of asphyxia include petechial hemorrhages, cyanosis, congestion, and soft tissue swelling due to increased venous pressure and fluid leakage from blood vessels.
Road accidents typically cause gross musculoskeletal or organ damage, severe haemorrhaging, airway blockage from blood, or traumatic asphyxiation from chest crushing. Railway suicides often result in decapitation or extensive body disintegration from being struck by a fast-moving train. Toxicology screens should be performed to check for alcohol or drugs which may have contributed to suicidal behavior. Electrical injuries may also complicate cases where high-voltage train systems are involved.
Strangulation, hanging, suffocation, road/railway injuries, and electrocution are common methods of suicidal death. Strangulation causes asphyxia by compressing the neck and blocking blood flow and air passage to the brain. Hanging causes cerebral hypoxia by compressing the neck and jugular veins. Suffocation involves blocking external airways. Road/railway injuries typically cause severe trauma, hemorrhage or organ damage. Electrocution usually causes cardiac arrhythmias and ventricular fibrillation leading to cardiac arrest. Autopsies look for neck furrows, petechiae, internal injuries or electrical marks depending on the method.
Retinitis pigmentosa is a slow degenerative, hereditary disease of the retina that involves the rods and cones. It typically appears as a recessive trait due to consanguinity of the parents. Patients experience night blindness in childhood, tunnel vision or central visual loss in middle age, and complete blindness in advanced age. Physical examination shows black spots resembling bone corpuscles across the retina, extremely attenuated retinal blood vessels, and pale optic discs, indicating optic nerve atrophy. There is no specific treatment currently available, but cataract surgery and rehabilitation services can help manage complications.
This document discusses refractive errors of the eye, including emmetropia, myopia, and hypermetropia. Emmetropia is the normal optical condition where light focuses on the retina. Myopia, or near-sightedness, occurs when light focuses in front of the retina. Symptoms include indistinct distant vision. Hypermetropia, or far-sightedness, is when light focuses behind the retina, causing blurred near vision and eye strain. Both conditions are typically corrected with spectacles, while myopia can also be treated through surgical procedures like LASIK in some cases.
This document provides guidance on evaluating patients presenting with gradual loss of vision. It outlines taking a history to determine factors like onset, progression, associated symptoms and medical history. The physical exam involves assessing visual acuity, the red reflex, visual fields and optic nerve/macula. Common causes of gradual vision loss include glaucoma, refractive error, cataract, diabetic retinopathy and age-related macular degeneration. Treatment depends on the underlying cause but may involve prescription lenses, medical management or referral for further evaluation.
Glaucoma is a group of eye conditions that damage the optic nerve, often caused by an increase in intraocular pressure. The aqueous humour maintains pressure in the eye and normally flows through the anterior chamber, draining out of the eye. In glaucoma, the drainage pathways become blocked, increasing pressure and damaging the optic nerve. There are several types of glaucoma including open-angle glaucoma, the most common type caused by slow drainage blockage, and closed-angle glaucoma caused by physical blockage of drainage canals. Treatment aims to lower pressure through eye drops or surgery and slow progression of vision loss.
ELECTROCUTION (suicidal)
- The most common cause of death from electrocution is cardiac arrhythmias leading to ventricular fibrillation and cardiac arrest. Less commonly, respiratory arrest can occur if the current passes through the thorax, causing spasms or paralysis of intercostal muscles and the diaphragm.
- External signs include an areola of blanched skin at the contact points and possible "crocodile skin" lesions from sparking over several centimeters if voltages were in the kilovolt range. Internal autopsy findings are often absent or non-specific since the most common mode of death is cardiac arrhythmia.
Diabetic retinopathy is a complication of diabetes mellitus where changes occur in the retina. It is a leading cause of vision loss among working age adults in Malaysia. The risk of retinopathy rises with longer duration of diabetes and poor blood glucose control. Annual eye screening is recommended to detect early signs and plan treatment. Laser photocoagulation is commonly used to treat early stages while vitrectomy may be used for advanced proliferative cases with vitreous hemorrhage. Anti-VEGF drugs combined with laser can also treat diabetic macular edema.
Cataracts are a clouding of the lens of the eye that can cause gradual vision loss. They are usually caused by aging but can be caused by other factors like diabetes, smoking, or UV exposure. Cataracts are diagnosed based on a decrease in the red reflex seen during eye exams. They can be treated surgically through phacoemulsification to remove the clouded lens and replace it with an intraocular lens, improving vision. Age-related macular degeneration (AMD) is a disease of the macula that causes central vision loss. Dry AMD involves drusen buildup while wet AMD has abnormal blood vessel growth. Treatments include vitamins for dry AMD and anti-VEGF injections or photod
The document summarizes the three stages of swallowing (deglutition):
1) Buccal stage where the tongue retracts forcing the bolus into the oropharynx.
2) Pharyngeal stage is involuntary where the soft palate and larynx elevate to prevent food entering the nasal cavity and lungs. The bolus moves into the upper esophagus.
3) Esophageal stage where peristalsis propels the bolus through the esophagus and into the stomach over 8-20 seconds while the lower esophageal and stomach sphincters relax.
The document describes a case of a 26-year-old man presenting with facial swelling, lumps in his armpits, chest pain for 3 months, and weight loss over 6 months. Examination found nail clubbing and a chest X-ray showed abnormalities. Biopsy and scans confirmed stage IV lung cancer. Nail clubbing is associated with lung diseases and cancers and results from vascular changes and growth factors from the lungs. Different types of biopsies are used to diagnose cancers including needle, endoscopic, and surgical biopsies. The anatomy of the chest is also described including structures like the ribs, sternum, and thoracic skeleton that make up the rib cage.
Mr. Lim, a 47-year-old man, presented with abdominal pain and diarrhea. Endoscopy revealed a duodenal ulcer and CT scan showed a 3cm pancreatic head mass suspected to be a gastrinoma. Laboratory tests found highly elevated gastrin and basal gastric acid levels consistent with Zollinger-Ellison Syndrome. Further tests demonstrated increased gastrin response to secretin stimulation, confirming a gastrin-secreting pancreatic tumor as the cause of his symptoms. Complications of ZES include peptic ulcers, diarrhea from excess acid inactivating pancreatic enzymes, and potential malignant spread of gastrinomas. Omeprazole was prescribed to reduce gastric acid levels and treat his
Congestive Heart failure is caused by low cardiac output and high sympathetic discharge. Diuretics reduce preload, ACE inhibitors lower afterload, beta blockers reduce sympathetic activity, and digitalis has inotropic effects. Newer medications target vasodilation and myosin activation to improve heart efficiency while lowering energy requirements. Combination therapy, following an assessment of cardiac function and volume status, is the most effective strategy to heart failure care.
PGx Analysis in VarSeq: A User’s PerspectiveGolden Helix
Since our release of the PGx capabilities in VarSeq, we’ve had a few months to gather some insights from various use cases. Some users approach PGx workflows by means of array genotyping or what seems to be a growing trend of adding the star allele calling to the existing NGS pipeline for whole genome data. Luckily, both approaches are supported with the VarSeq software platform. The genotyping method being used will also dictate what the scope of the tertiary analysis will be. For example, are your PGx reports a standalone pipeline or would your lab’s goal be to handle a dual-purpose workflow and report on PGx + Diagnostic findings.
The purpose of this webcast is to:
Discuss and demonstrate the approaches with array and NGS genotyping methods for star allele calling to prep for downstream analysis.
Following genotyping, explore alternative tertiary workflow concepts in VarSeq to handle PGx reporting.
Moreover, we will include insights users will need to consider when validating their PGx workflow for all possible star alleles and options you have for automating your PGx analysis for large number of samples. Please join us for a session dedicated to the application of star allele genotyping and subsequent PGx workflows in our VarSeq software.
Discover the benefits of homeopathic medicine for irregular periods with our guide on 5 common remedies. Learn how these natural treatments can help regulate menstrual cycles and improve overall menstrual health.
Visit Us: https://drdeepikashomeopathy.com/service/irregular-periods-treatment/
- Video recording of this lecture in English language: https://youtu.be/RvdYsTzgQq8
- Video recording of this lecture in Arabic language: https://youtu.be/ECILGWtgZko
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Nutritional deficiency Disorder are problems in india.
It is very important to learn about Indian child's nutritional parameters as well the Disease related to alteration in their Nutrition.
TEST BANK For Brunner and Suddarth's Textbook of Medical-Surgical Nursing, 14...Donc Test
TEST BANK For Brunner and Suddarth's Textbook of Medical-Surgical Nursing, 14th Edition (Hinkle, 2017) Verified Chapter's 1 - 73 Complete.pdf
TEST BANK For Brunner and Suddarth's Textbook of Medical-Surgical Nursing, 14th Edition (Hinkle, 2017) Verified Chapter's 1 - 73 Complete.pdf
TEST BANK For Brunner and Suddarth's Textbook of Medical-Surgical Nursing, 14th Edition (Hinkle, 2017) Verified Chapter's 1 - 73 Complete.pdf
Travel Clinic Cardiff: Health Advice for International TravelersNX Healthcare
Travel Clinic Cardiff offers comprehensive travel health services, including vaccinations, travel advice, and preventive care for international travelers. Our expert team ensures you are well-prepared and protected for your journey, providing personalized consultations tailored to your destination. Conveniently located in Cardiff, we help you travel with confidence and peace of mind. Visit us: www.nxhealthcare.co.uk
Giloy in Ayurveda - Classical Categorization and SynonymsPlanet Ayurveda
Giloy, also known as Guduchi or Amrita in classical Ayurvedic texts, is a revered herb renowned for its myriad health benefits. It is categorized as a Rasayana, meaning it has rejuvenating properties that enhance vitality and longevity. Giloy is celebrated for its ability to boost the immune system, detoxify the body, and promote overall wellness. Its anti-inflammatory, antipyretic, and antioxidant properties make it a staple in managing conditions like fever, diabetes, and stress. The versatility and efficacy of Giloy in supporting health naturally highlight its importance in Ayurveda. At Planet Ayurveda, we provide a comprehensive range of health services and 100% herbal supplements that harness the power of natural ingredients like Giloy. Our products are globally available and affordable, ensuring that everyone can benefit from the ancient wisdom of Ayurveda. If you or your loved ones are dealing with health issues, contact Planet Ayurveda at 01725214040 to book an online video consultation with our professional doctors. Let us help you achieve optimal health and wellness naturally.
Nano-gold for Cancer Therapy chemistry investigatory projectSIVAVINAYAKPK
chemistry investigatory project
The development of nanogold-based cancer therapy could revolutionize oncology by providing a more targeted, less invasive treatment option. This project contributes to the growing body of research aimed at harnessing nanotechnology for medical applications, paving the way for future clinical trials and potential commercial applications.
Cancer remains one of the leading causes of death worldwide, prompting the need for innovative treatment methods. Nanotechnology offers promising new approaches, including the use of gold nanoparticles (nanogold) for targeted cancer therapy. Nanogold particles possess unique physical and chemical properties that make them suitable for drug delivery, imaging, and photothermal therapy.
This presentation gives information on the pharmacology of Prostaglandins, Thromboxanes and Leukotrienes i.e. Eicosanoids. Eicosanoids are signaling molecules derived from polyunsaturated fatty acids like arachidonic acid. They are involved in complex control over inflammation, immunity, and the central nervous system. Eicosanoids are synthesized through the enzymatic oxidation of fatty acids by cyclooxygenase and lipoxygenase enzymes. They have short half-lives and act locally through autocrine and paracrine signaling.
Demystifying Fallopian Tube Blockage- Grading the Differences and Implication...
Crepitus
1. 1
CrepitusPROBLEM BASED LEARNING (PBL)
PREPARED BY: MUHAMMAD ARIFF B. MAHDZUB
BACHELOR MEDICINE AND SURGERY (MBBS)
UNIVERSITY COLLEGE SHAHPUTRA, KUANTAN
2. What is crepitus?
• term to describe the grating, crackling or
popping sounds and sensations experienced
under the skin and joints
• a crackling sensation due to the presence of
air in the subcutaneous tissue.
3. Types of crepitus
Bone Crepitus
Joint Crepitus
Crepitus of bursitis
Crepitus of tenosynovitis
the inflammation of one or
more bursae (small sacs) of
synovial fluid in the body
two fragments of a fracture are
moved against each other the affected joint is passively moved with
one hand, while the other hand is placed
on the joint to feel the crepitus.
the inflammation of the fluid-filled sheath
(called the synovium) that surrounds a
tendon.
4. Causes??
• The sound can be created when two rough
surfaces in an organism's body come into contact
• when the cartilage around joints has eroded away
and the surfaces in the joint start to grind against
one another, or when the fracture surfaces of two
broken bones rub together
• Eg. - osteoarthritis
- rheumatoid arthritis
• Crepitus is a common sign of bone fracture.
5. Crepitus can easily be introduced by exerting a
small amount of force on a joint, thus 'cracking
it'.
6. Why this is happening?
• This is caused by bubbles of nitrogen forming
in the synovial fluid bursting.
• Almost every joint in the body can be 'cracked'
in this way, but the joints which require the
least amount of effort include the hallux,
knuckles and neck joints
7. Other clinical significance
• In soft tissues, crepitus can be produced when
gas is introduced into an area where it normally is
not present.
• sounds produced by lung conditions such as
interstitial lung disease—these are also referred
to as "rales".
• Crepitus is often loud enough to be heard by the
human ear, although a stethoscope may be
needed to detect instances caused by respiratory
diseases
8. Cont.
• post-surgical complications involved anaerobic
infection by Clostridium perfringens strains,
which can cause gas gangrene in tissues, also
giving rise to crepitus.
• Subcutaneous crepitus (or surgical
emphysema) is a crackling sound resulting
from subcutaneous emphysema, or air
trapped in the subcutaneous tissues.