The nervous system and endocrine system are the two coordination systems in animals that allow them to respond to stimuli in the environment. The nervous system uses nerve impulses transmitted through neurons to enable rapid responses, while the endocrine system uses chemical messengers called hormones transported through the bloodstream to enable slower but longer-lasting responses. Plants also respond to stimuli but do not have nervous or endocrine systems and instead rely on plant hormones to coordinate slow, predetermined responses.