This document outlines the World Health Organization's 2016 classification of central nervous system tumors. It lists 17 categories of CNS tumors and provides brief descriptions of some of the tumor types within categories 1, 2, and 10, including diffuse astrocytic and oligodendroglial tumors, other astrocytic tumors characterized by more circumscribed growth and specific genetic alterations, and the various subtypes of meningiomas ranging from low to high grade.

1. CNS TUMORS- WHO
Classification 2016
DR ANAMIKA DEV

2. 1. Diffuse astrocytic & oligodendroglial tumours
2. Other astrocytic tumours
3. Ependymal tumours
4. Other gliomas
5. Choroid plexus tumours
6. Neuronal & Mixed neuronal-glial tumours
7. Tumours of pineal region
8. Embryonal tumours
9. Tumours of Cranial & Paraspinal nerves
10. Meningiomas
11. Mesenchymal, non-meningothelial tumours
12. Melanocytic tumours
13. Lymphomas
14. Histiocyic tumours
15. GCT
16. Tumours of sellar regions
17. Metastatic tumours

3. 1.DIFFUSE ASTROCYTIC & OLIGODENDROGLIAL
TUMOURS: (No WHO grade I infiltrating astrocytoma)

4. 2.OTHER ASTROCYTIC TUMOURS:
More circumscribed growth pattern,
Lack IDH gene family alterations
Frequently have BRAF alterations/ TSC1/TSC2 mutations

5. 3.Ependymal tumors

6. 4.Other gliomas

7. 5. Choroid plexus tumors
• Choroid plexus papilloma
• Atypical Choroid plexus papilloma
• Choroid plexus carcinoma

8. Meningiomas
• WHO Grade 1
– Meningothelial meningioma
– Fibroblastic
– Transitional
– Psamommatous
– Secretory
– Microcystic
– Angiomatous
– Lymphoplasmacyte- rich
– metaplastic
• WHO Grade 2
– Clear cell
– Chordoid
– atypical
• WHO Grade 3
– Rhabdoid
– Papillary
– Anaplastc