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CNS TUMORS- WHO
Classification 2016
DR ANAMIKA DEV
1. Diffuse astrocytic & oligodendroglial tumours
2. Other astrocytic tumours
3. Ependymal tumours
4. Other gliomas
5. Choroid plexus tumours
6. Neuronal & Mixed neuronal-glial tumours
7. Tumours of pineal region
8. Embryonal tumours
9. Tumours of Cranial & Paraspinal nerves
10. Meningiomas
11. Mesenchymal, non-meningothelial tumours
12. Melanocytic tumours
13. Lymphomas
14. Histiocyic tumours
15. GCT
16. Tumours of sellar regions
17. Metastatic tumours
1.DIFFUSE ASTROCYTIC & OLIGODENDROGLIAL
TUMOURS: (No WHO grade I infiltrating astrocytoma)
2.OTHER ASTROCYTIC TUMOURS:
More circumscribed growth pattern,
Lack IDH gene family alterations
Frequently have BRAF alterations/ TSC1/TSC2 mutations
3.Ependymal tumors
4.Other gliomas
5. Choroid plexus tumors
• Choroid plexus papilloma
• Atypical Choroid plexus papilloma
• Choroid plexus carcinoma
Meningiomas
• WHO Grade 1
– Meningothelial meningioma
– Fibroblastic
– Transitional
– Psamommatous
– Secretory
– Microcystic
– Angiomatous
– Lymphoplasmacyte- rich
– metaplastic
• WHO Grade 2
– Clear cell
– Chordoid
– atypical
• WHO Grade 3
– Rhabdoid
– Papillary
– Anaplastc

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Cns tumors who classification 2016

  • 1. CNS TUMORS- WHO Classification 2016 DR ANAMIKA DEV
  • 2. 1. Diffuse astrocytic & oligodendroglial tumours 2. Other astrocytic tumours 3. Ependymal tumours 4. Other gliomas 5. Choroid plexus tumours 6. Neuronal & Mixed neuronal-glial tumours 7. Tumours of pineal region 8. Embryonal tumours 9. Tumours of Cranial & Paraspinal nerves 10. Meningiomas 11. Mesenchymal, non-meningothelial tumours 12. Melanocytic tumours 13. Lymphomas 14. Histiocyic tumours 15. GCT 16. Tumours of sellar regions 17. Metastatic tumours
  • 3. 1.DIFFUSE ASTROCYTIC & OLIGODENDROGLIAL TUMOURS: (No WHO grade I infiltrating astrocytoma)
  • 4. 2.OTHER ASTROCYTIC TUMOURS: More circumscribed growth pattern, Lack IDH gene family alterations Frequently have BRAF alterations/ TSC1/TSC2 mutations
  • 7. 5. Choroid plexus tumors • Choroid plexus papilloma • Atypical Choroid plexus papilloma • Choroid plexus carcinoma
  • 8. Meningiomas • WHO Grade 1 – Meningothelial meningioma – Fibroblastic – Transitional – Psamommatous – Secretory – Microcystic – Angiomatous – Lymphoplasmacyte- rich – metaplastic • WHO Grade 2 – Clear cell – Chordoid – atypical • WHO Grade 3 – Rhabdoid – Papillary – Anaplastc