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 
Dhuha F Shamsaldeen
 Identify the metabolic functions of the liver and the
alterations in these functions that occur with liver
disease.
 Explain liver function tests and the clinical manifestations
of liver dysfunction in relation to pathophysiology
alterations of the liver.
 Describe the medical, surgical, and nursing management
of patients with cirrhosis.
 Use the nursing process as a framework for care of the
patient with cirrhosis of the liver.
 The liver, is the largest gland of the body, located behind
the ribs in the upper right portion of the abdominal cavity.
 Glucose metabolism.
 Ammonia conversion.
 Protein metabolism.
 Fat metabolism.
 Vitamins and iron storage.
 Bile formation.
 Bilirubin excretion.
 Drug metabolism.
 N/V
 Anorexia
 Abdominal distention
 Changes in bowel habits
 Weight loss
 Weakness and fatigue
 Abdominal pain
 Bleeding in ( skin, stool, urine )
 Edema
 Dark urine
 Ascites
 Jaundice
 
 Is a chronic disease characterized by replacement of
normal liver tissue with diffuse fibrosis that disrupt the
structure and function of the liver.
Types of the hepatic
cirrhosis :
Alcoholic cirrhosis
In which the scar tissue
characteristically
surround the portal al
areas .
Biliary cirrhosis
In which scarring occurs
in the liver around the
bile ducts. This type of
cirrhosis usually result
from chronic biliary
obstruction and infection.
Postnecrotic cirrhosis
In which there are broad
bands of scar tissue. This
is a late result of a
previous bout of acute
viral hepatitis.
compensated decompensated
Intermittent mild fever
Vascular spiders
Palmar erythema ( reddened palms )
Unexplained epistaxis
ankle edema
Vague morning indigestion
Flatulent dyspepsia
Abdominal pain
Enlarged liver
Splenomegaly
Ascites
Jaundice
Fatigue
Muscle wasting
Weight loss
Continuous of liver
Clubbing of liver
pruritus
Spontaneous bruising
Epistaxis
Hypotension
Spare body hair
White nails
Gonadal atropy
 
 Autoimmune
 Poor nutrition
 Toxic substances
 Infections
 Older adults ( age )
 Feeding habits
 Adults circumcision
 Direct Bilirubin
 Indirect Bilirubin
 Serum amylase
 Serum lipase
 Ammonia
 AST ( Aspartate Amino Transfers )
 ALT ( Alanine Amino Transfers )
 SGOT ( Serum Glutamic Oxaloacetic Transaminase)
 LDH ( Lactic Acid Dehydrogenase )
 ALP ( Alkaine Phosphatase )
 GGT ( G-Glutamyl Transfers)
 CT scan
 MRI
 Liver biopsy
 Antacids / Histamine-2 ( H2 ) antagnosis:
To decrease gastric distress and minimize the possibility of
GI bleeding.
 Vitamins and nutritional supplements:
To promote healing of damaged liver cells and improve the
patient`s general nutritional status.
 Potassium-sparing diuretics such as spironolactone or
triamterene ( Dyrenium ):
To decrease ascites and minimize the fluid and electrolyte
changes.
 
Nursing interventions rationale Expected outcomes
1. Assess level of activity
tolerance and degree of
fatigue when performing
routine activities of daily
living.
2. Assist when activities and
hygiene when fatigued.
3. Encourage rest when
fatigued or when abdominal
pain or discomfort occurs.
4. Assist with selection and
pacing of desired activities
and exercise.
5. Provide diet high in
carbohydrates with protein
intake consistent with liver
function.
6. Administer supplemental
vitamins ( A, B complex, C,
and K ).
1. Provides baseline for future
assessment and criteria for
assessment of effectiveness
of environment.
2. Promotes exercise and
hygiene within pt`s level of
tolerance.
3. Conserves energy to
protects the liver.
4. Stimulates patient`s interest
in selected activities.
5. Provides calories for energy
and protein for healing.
6. Provides additional nutrient.
• Exhibits increased interest in
activity and events.
• Participate in activities and
gradually increases exercise
within physical limits.
• Reports increased in
strength and well-being.
• Reports absence of
abdominal pain and
discomfort.
• Plans activities to allow
ample periods of rest.
• Takes vitamins as
prescribed.
Nursing interventions rationale Expected outcomes
1. Assess dietary intake and
nutritional status through diet
history and diary, daily weight
measurements, and laboratory
data.
2. Provide diet high in
carbohydrates with protein
intake consistent with liver
function.
3. Assist pt in identifying low
sodium foods.
4. Elevate the head of the bed
during meals.
5. Provides oral hygiene before
meals and pleasant environment
for meals at meal time.
6. Offer smaller, more frequent
meals.
7. Eliminate alcohol.
8. Apply an ice collar for nausea.
1. Identifies deficits in nutritional
intake and adequacy of
nutritional state.
2. Provides calories for energy,
sparing protein for healing.
3. Reduces edema and ascites
formation.
4. Reduces discomfort from
abdominal distention.
5. Promotes positive environment
and increased appetite; reduced
unpleasant taste.
6. Decrease feeling of fullness and
bloating.
7. Eliminates “empty calories” and
further damage from alcohol.
• Exhibits improved nutritional
status by increased weight (
without fluid retention ) and
improved laboratory data.
• States rationale for dietary
modifications.
• Identifies foods high in
carbohydrates and within protein
requirements ( moderate to high
protein in cirrhosis ).
• Reports improved appetite.
• Participates in oral hygiene
measures.
• Gains weight without increased
edema or ascites formation.
Nursing interventions Rationale Expected outcomes
1. Assess degree of
discomfort r/t pruritus and
edema.
2. Note and record degree of
jaundice and extent of
edema.
3. Keep patient`s fingernails
short and smooth.
4. Provide frequent skin care;
avoid use of soaps and
alcohol-based lotions.
5. Massage every 2 h with
emollients; turn every 2 h.
6. Recommend avoiding use
of harsh detergents.
7. Assess skin integrity every
4-8 hrs.
1. Assists in determining
appropriate interventions.
2. Provides baseline for
detecting changes and
evaluating effectiveness of
interventions.
3. Prevents skin excoriation
and infection from
scratching.
4. Removes waste products
from skin while preventing
dryness of skin.
5. Promotes mobilization of
edema.
• Exhibits intact skin without
redness, excoriation, or
breakdown.
• Reports relief from pruritus.
• Exhibits no skin excoriation
from scratching.
• Uses nondrying soaps and
lotions.
• Turns self periodically,
exhibits reduced edema of
dependent parts of the body.
• Exhibits decreased edema;
normal skin turgor.
Nursing interventions rationale Expected outcomes
1. Maintain bed rest within
pt experiences
abdominal discomfort.
2. Administer
antispasmodic and
analgesic agents as
prescribed.
3. Observe, record, and
report presence and
character of pain and
discomfort.
4. Reduce fluid and
sodium intake if
prescribed.
5. Encourage the use of
distracting activities
such as music, reading,
or meditation.
1. Reduces metabolic
demands and protects
the liver.
2. Reduces irritability of
the GI tract and
decrease abdominal
pain and discomfort.
3. Provides baseline to
detect further
deterioration of status
and to evaluate
interventions.
4. Removal of a ascites
fluid may decrease
abdominal discomfort.
5. Distraction may limit the
perception of pain.
• Reports pain and
discomfort if present.
• Maintains bed rest and
decrease activity in
presence of pain.
• Takes antispasmodic
and analgesics as
indicated and as
prescribed.
• Reports decreased pain
and abdominal
discomfort.
• Reduce sodium and fluid
intake to prescribed
levels if indicated to treat
ascites.
• Exhibits decreased
abdominal girth and
appropriate weight
changes.
Nursing interventions rationale Expected outcomes
1. Restrict sodium and
fluid intake if prescribed.
2. Administer diuretics,
potassium, and protein
supplements as
prescribed.
3. Record intake and
output every 1-8 h
depending on response
to interventions and on
pt acuity.
4. Measure and record
abdominal girth and
weight daily.
5. Explain rationale for
sodium and fluid
restrictions.
1. Minimize formation of
ascites and edema.
2. Promotes excretion of
fluid through the kidneys
and maintenance of
normal fluid and
electrolyte balance.
3. Indicates effectiveness
of treatment and
adequacy of fluid intake.
4. Monitors change in
ascites formation and
fluid accumulation.
5. Promotes pt`s
understanding of
restriction and
cooperation with it.
• Consumes diet low
sodium and within
prescribed fluid
restriction.
• Takes diuretics,
potassium, and protein
supplement as indicated
without experiencing
side effects.
• Exhibits increased urine
output.
• Exhibits decreasing
abdominal girth.
• Shows a decrease in
ascites with decrease
weight .
Nursing interventions rationale Expected outcomes
1. Record temperature
regularly.
2. Encourage fluid intake.
3. Apply cool sponges or
ice bag for elevated
temperature.
4. Administer antibiotics as
prescribed.
5. Avoid exposure to
infections.
6. Keep pt at rest while
temperature is
evaluated.
7. Assess for abdominal
pain, tenderness.
8. Use sterile technique for
all invasive procedures.
1. Provides baseline to
detect fever and to
evaluate interventions.
2. Corrects fluid less from
perspiration and fever
and increases patient's
level of comfort.
3. Minimize risk of further
infection and further
increase in body
temperature.
4. Reduce metabolic rate.
• Exhibits normal
temperature and reports
absence of chills or
sweating.
• Demonstrates adequate
intake of fluid.
• Exhibits no evidence of
local or systemic
infection.
 Promoting rest
 Improving nutritional status
 Providing skin care
 Reducing risk of injury
 www.cirrhosisoftheliver.us
 http://www.nlm.nih.gov/medlineplus/ency/article/000255.
htm
 Kluwer, W., Williams, L., & Wilkins, L. (2010).
Assessment and Management of Patient With Hepatic
Disorders. In Smeltzer S.C., Bare B.G., Hinkle J.L., &
Cheever K.H. (eds), Medical-Surgical Nursing (pp 1116-
1168) (12th ed.). New York: Lippincott-Raven.

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Cirrhosis

  • 1.   Dhuha F Shamsaldeen
  • 2.  Identify the metabolic functions of the liver and the alterations in these functions that occur with liver disease.  Explain liver function tests and the clinical manifestations of liver dysfunction in relation to pathophysiology alterations of the liver.  Describe the medical, surgical, and nursing management of patients with cirrhosis.  Use the nursing process as a framework for care of the patient with cirrhosis of the liver.
  • 3.  The liver, is the largest gland of the body, located behind the ribs in the upper right portion of the abdominal cavity.
  • 4.  Glucose metabolism.  Ammonia conversion.  Protein metabolism.  Fat metabolism.  Vitamins and iron storage.  Bile formation.  Bilirubin excretion.  Drug metabolism.
  • 5.  N/V  Anorexia  Abdominal distention  Changes in bowel habits  Weight loss  Weakness and fatigue  Abdominal pain  Bleeding in ( skin, stool, urine )  Edema  Dark urine  Ascites  Jaundice
  • 7.  Is a chronic disease characterized by replacement of normal liver tissue with diffuse fibrosis that disrupt the structure and function of the liver.
  • 8.
  • 9. Types of the hepatic cirrhosis : Alcoholic cirrhosis In which the scar tissue characteristically surround the portal al areas . Biliary cirrhosis In which scarring occurs in the liver around the bile ducts. This type of cirrhosis usually result from chronic biliary obstruction and infection. Postnecrotic cirrhosis In which there are broad bands of scar tissue. This is a late result of a previous bout of acute viral hepatitis.
  • 10. compensated decompensated Intermittent mild fever Vascular spiders Palmar erythema ( reddened palms ) Unexplained epistaxis ankle edema Vague morning indigestion Flatulent dyspepsia Abdominal pain Enlarged liver Splenomegaly Ascites Jaundice Fatigue Muscle wasting Weight loss Continuous of liver Clubbing of liver pruritus Spontaneous bruising Epistaxis Hypotension Spare body hair White nails Gonadal atropy
  • 11.
  • 13.  Autoimmune  Poor nutrition  Toxic substances  Infections
  • 14.  Older adults ( age )
  • 15.  Feeding habits  Adults circumcision
  • 16.  Direct Bilirubin  Indirect Bilirubin  Serum amylase  Serum lipase  Ammonia  AST ( Aspartate Amino Transfers )  ALT ( Alanine Amino Transfers )  SGOT ( Serum Glutamic Oxaloacetic Transaminase)  LDH ( Lactic Acid Dehydrogenase )  ALP ( Alkaine Phosphatase )  GGT ( G-Glutamyl Transfers)
  • 17.  CT scan  MRI  Liver biopsy
  • 18.  Antacids / Histamine-2 ( H2 ) antagnosis: To decrease gastric distress and minimize the possibility of GI bleeding.  Vitamins and nutritional supplements: To promote healing of damaged liver cells and improve the patient`s general nutritional status.  Potassium-sparing diuretics such as spironolactone or triamterene ( Dyrenium ): To decrease ascites and minimize the fluid and electrolyte changes.
  • 20. Nursing interventions rationale Expected outcomes 1. Assess level of activity tolerance and degree of fatigue when performing routine activities of daily living. 2. Assist when activities and hygiene when fatigued. 3. Encourage rest when fatigued or when abdominal pain or discomfort occurs. 4. Assist with selection and pacing of desired activities and exercise. 5. Provide diet high in carbohydrates with protein intake consistent with liver function. 6. Administer supplemental vitamins ( A, B complex, C, and K ). 1. Provides baseline for future assessment and criteria for assessment of effectiveness of environment. 2. Promotes exercise and hygiene within pt`s level of tolerance. 3. Conserves energy to protects the liver. 4. Stimulates patient`s interest in selected activities. 5. Provides calories for energy and protein for healing. 6. Provides additional nutrient. • Exhibits increased interest in activity and events. • Participate in activities and gradually increases exercise within physical limits. • Reports increased in strength and well-being. • Reports absence of abdominal pain and discomfort. • Plans activities to allow ample periods of rest. • Takes vitamins as prescribed.
  • 21. Nursing interventions rationale Expected outcomes 1. Assess dietary intake and nutritional status through diet history and diary, daily weight measurements, and laboratory data. 2. Provide diet high in carbohydrates with protein intake consistent with liver function. 3. Assist pt in identifying low sodium foods. 4. Elevate the head of the bed during meals. 5. Provides oral hygiene before meals and pleasant environment for meals at meal time. 6. Offer smaller, more frequent meals. 7. Eliminate alcohol. 8. Apply an ice collar for nausea. 1. Identifies deficits in nutritional intake and adequacy of nutritional state. 2. Provides calories for energy, sparing protein for healing. 3. Reduces edema and ascites formation. 4. Reduces discomfort from abdominal distention. 5. Promotes positive environment and increased appetite; reduced unpleasant taste. 6. Decrease feeling of fullness and bloating. 7. Eliminates “empty calories” and further damage from alcohol. • Exhibits improved nutritional status by increased weight ( without fluid retention ) and improved laboratory data. • States rationale for dietary modifications. • Identifies foods high in carbohydrates and within protein requirements ( moderate to high protein in cirrhosis ). • Reports improved appetite. • Participates in oral hygiene measures. • Gains weight without increased edema or ascites formation.
  • 22. Nursing interventions Rationale Expected outcomes 1. Assess degree of discomfort r/t pruritus and edema. 2. Note and record degree of jaundice and extent of edema. 3. Keep patient`s fingernails short and smooth. 4. Provide frequent skin care; avoid use of soaps and alcohol-based lotions. 5. Massage every 2 h with emollients; turn every 2 h. 6. Recommend avoiding use of harsh detergents. 7. Assess skin integrity every 4-8 hrs. 1. Assists in determining appropriate interventions. 2. Provides baseline for detecting changes and evaluating effectiveness of interventions. 3. Prevents skin excoriation and infection from scratching. 4. Removes waste products from skin while preventing dryness of skin. 5. Promotes mobilization of edema. • Exhibits intact skin without redness, excoriation, or breakdown. • Reports relief from pruritus. • Exhibits no skin excoriation from scratching. • Uses nondrying soaps and lotions. • Turns self periodically, exhibits reduced edema of dependent parts of the body. • Exhibits decreased edema; normal skin turgor.
  • 23. Nursing interventions rationale Expected outcomes 1. Maintain bed rest within pt experiences abdominal discomfort. 2. Administer antispasmodic and analgesic agents as prescribed. 3. Observe, record, and report presence and character of pain and discomfort. 4. Reduce fluid and sodium intake if prescribed. 5. Encourage the use of distracting activities such as music, reading, or meditation. 1. Reduces metabolic demands and protects the liver. 2. Reduces irritability of the GI tract and decrease abdominal pain and discomfort. 3. Provides baseline to detect further deterioration of status and to evaluate interventions. 4. Removal of a ascites fluid may decrease abdominal discomfort. 5. Distraction may limit the perception of pain. • Reports pain and discomfort if present. • Maintains bed rest and decrease activity in presence of pain. • Takes antispasmodic and analgesics as indicated and as prescribed. • Reports decreased pain and abdominal discomfort. • Reduce sodium and fluid intake to prescribed levels if indicated to treat ascites. • Exhibits decreased abdominal girth and appropriate weight changes.
  • 24. Nursing interventions rationale Expected outcomes 1. Restrict sodium and fluid intake if prescribed. 2. Administer diuretics, potassium, and protein supplements as prescribed. 3. Record intake and output every 1-8 h depending on response to interventions and on pt acuity. 4. Measure and record abdominal girth and weight daily. 5. Explain rationale for sodium and fluid restrictions. 1. Minimize formation of ascites and edema. 2. Promotes excretion of fluid through the kidneys and maintenance of normal fluid and electrolyte balance. 3. Indicates effectiveness of treatment and adequacy of fluid intake. 4. Monitors change in ascites formation and fluid accumulation. 5. Promotes pt`s understanding of restriction and cooperation with it. • Consumes diet low sodium and within prescribed fluid restriction. • Takes diuretics, potassium, and protein supplement as indicated without experiencing side effects. • Exhibits increased urine output. • Exhibits decreasing abdominal girth. • Shows a decrease in ascites with decrease weight .
  • 25. Nursing interventions rationale Expected outcomes 1. Record temperature regularly. 2. Encourage fluid intake. 3. Apply cool sponges or ice bag for elevated temperature. 4. Administer antibiotics as prescribed. 5. Avoid exposure to infections. 6. Keep pt at rest while temperature is evaluated. 7. Assess for abdominal pain, tenderness. 8. Use sterile technique for all invasive procedures. 1. Provides baseline to detect fever and to evaluate interventions. 2. Corrects fluid less from perspiration and fever and increases patient's level of comfort. 3. Minimize risk of further infection and further increase in body temperature. 4. Reduce metabolic rate. • Exhibits normal temperature and reports absence of chills or sweating. • Demonstrates adequate intake of fluid. • Exhibits no evidence of local or systemic infection.
  • 26.  Promoting rest  Improving nutritional status  Providing skin care  Reducing risk of injury
  • 27.  www.cirrhosisoftheliver.us  http://www.nlm.nih.gov/medlineplus/ency/article/000255. htm  Kluwer, W., Williams, L., & Wilkins, L. (2010). Assessment and Management of Patient With Hepatic Disorders. In Smeltzer S.C., Bare B.G., Hinkle J.L., & Cheever K.H. (eds), Medical-Surgical Nursing (pp 1116- 1168) (12th ed.). New York: Lippincott-Raven.