Molecular basis of Skeletal Muscle ContractionArulSood2
The ppt aims to explain the molecular basis of skeletal muscle contraction and certain applied aspects of the same. Sources include Guyton and Hall's Textbook of Physiology (South-Asia edition, Vol. 2) and C.L. Ghai's Textbook for Practical Physiology.
1) Proteins in the diet are broken down into smaller peptides and individual amino acids through digestion by proteolytic enzymes in the stomach, pancreas, and intestines.
2) In the liver, amino acids are broken down through transamination and transdeamination reactions to produce ammonia, which is highly toxic.
3) Ammonia is detoxified in the liver through the urea cycle into urea, which is excreted in the urine. Deficiencies in urea cycle enzymes can cause a toxic buildup of ammonia in the blood.
This document discusses the three main types of muscle tissue - skeletal, cardiac, and smooth muscle. It describes their structural and physiological characteristics, including that skeletal muscle is striated and voluntary, cardiac muscle is striated and involuntary, and smooth muscle is non-striated and involuntary. The document also examines the structure of skeletal muscle fibers down to the sarcomere level and explores muscle contraction types, the role of ATP as an energy source, and factors that influence muscle tension and can lead to fatigue.
The document summarizes the process of carbohydrate digestion in humans. It begins with mechanical digestion in the mouth through chewing. Chemical digestion then starts with salivary amylase breaking down some starch in the mouth. In the stomach, further mixing occurs and ptyalin continues breaking down starch, with around 30-40% being digested. The acidic stomach stops further digestion. In the small intestine, pancreatic amylase and intestinal enzymes hydrolyze starches and sugars into monosaccharides like glucose and fructose which are then absorbed into the bloodstream. Certain carbohydrates like cellulose are not digested but provide fiber.
Glycolysis is the breakdown of glucose to pyruvate through a series of enzyme-catalyzed reactions. It occurs in the cytosol and consists of a preparatory phase requiring ATP and a payoff phase generating ATP. Key steps include phosphorylation by hexokinase, aldolase cleavage, substrate-level phosphorylation by phosphoglycerate kinase, and pyruvate formation by pyruvate kinase. Glycolytic enzymes are regulated by feedback inhibition and metabolites like fructose 2,6-bisphosphate and AMP/ATP ratios to control flux through the pathway.
There are three important ketone bodies - aceto-acetate, acetone, and β-hydroxybutyrate. Ketone body synthesis occurs in the liver from acetyl-CoA but their utilization occurs in other tissues like cardiac muscle and brain. Ketone bodies are produced during periods of fasting or starvation and act as an alternative fuel source. Increased ketone body production can lead to metabolic acidosis if the buffering system is overwhelmed by too many hydrogen ions being released.
The document provides an overview of carbohydrate metabolism. It discusses the major pathways involved, including glycolysis, the citric acid cycle, and the hexose monophosphate shunt. Glycolysis converts glucose to pyruvate, producing a small amount of ATP. The citric acid cycle further oxidizes pyruvate and acetyl-CoA, generating the majority of the cell's ATP through oxidative phosphorylation. The hexose monophosphate shunt provides an alternative pathway for glucose oxidation and generates NADPH.
Molecular basis of Skeletal Muscle ContractionArulSood2
The ppt aims to explain the molecular basis of skeletal muscle contraction and certain applied aspects of the same. Sources include Guyton and Hall's Textbook of Physiology (South-Asia edition, Vol. 2) and C.L. Ghai's Textbook for Practical Physiology.
1) Proteins in the diet are broken down into smaller peptides and individual amino acids through digestion by proteolytic enzymes in the stomach, pancreas, and intestines.
2) In the liver, amino acids are broken down through transamination and transdeamination reactions to produce ammonia, which is highly toxic.
3) Ammonia is detoxified in the liver through the urea cycle into urea, which is excreted in the urine. Deficiencies in urea cycle enzymes can cause a toxic buildup of ammonia in the blood.
This document discusses the three main types of muscle tissue - skeletal, cardiac, and smooth muscle. It describes their structural and physiological characteristics, including that skeletal muscle is striated and voluntary, cardiac muscle is striated and involuntary, and smooth muscle is non-striated and involuntary. The document also examines the structure of skeletal muscle fibers down to the sarcomere level and explores muscle contraction types, the role of ATP as an energy source, and factors that influence muscle tension and can lead to fatigue.
The document summarizes the process of carbohydrate digestion in humans. It begins with mechanical digestion in the mouth through chewing. Chemical digestion then starts with salivary amylase breaking down some starch in the mouth. In the stomach, further mixing occurs and ptyalin continues breaking down starch, with around 30-40% being digested. The acidic stomach stops further digestion. In the small intestine, pancreatic amylase and intestinal enzymes hydrolyze starches and sugars into monosaccharides like glucose and fructose which are then absorbed into the bloodstream. Certain carbohydrates like cellulose are not digested but provide fiber.
Glycolysis is the breakdown of glucose to pyruvate through a series of enzyme-catalyzed reactions. It occurs in the cytosol and consists of a preparatory phase requiring ATP and a payoff phase generating ATP. Key steps include phosphorylation by hexokinase, aldolase cleavage, substrate-level phosphorylation by phosphoglycerate kinase, and pyruvate formation by pyruvate kinase. Glycolytic enzymes are regulated by feedback inhibition and metabolites like fructose 2,6-bisphosphate and AMP/ATP ratios to control flux through the pathway.
There are three important ketone bodies - aceto-acetate, acetone, and β-hydroxybutyrate. Ketone body synthesis occurs in the liver from acetyl-CoA but their utilization occurs in other tissues like cardiac muscle and brain. Ketone bodies are produced during periods of fasting or starvation and act as an alternative fuel source. Increased ketone body production can lead to metabolic acidosis if the buffering system is overwhelmed by too many hydrogen ions being released.
The document provides an overview of carbohydrate metabolism. It discusses the major pathways involved, including glycolysis, the citric acid cycle, and the hexose monophosphate shunt. Glycolysis converts glucose to pyruvate, producing a small amount of ATP. The citric acid cycle further oxidizes pyruvate and acetyl-CoA, generating the majority of the cell's ATP through oxidative phosphorylation. The hexose monophosphate shunt provides an alternative pathway for glucose oxidation and generates NADPH.
Metabolism of Brached Chain Amino Acid (Valine, Isoleucine, Leucine)Ashok Katta
Branched chain amino acids include leucine, isoleucine, and valine. They are broken down by the branched chain alpha-ketoacid dehydrogenase complex in mitochondria. A defect in this enzyme can cause branched chain ketoaciduria, where patients accumulate branched chain amino acids and their keto acids in their urine, which smells like maple syrup or burnt sugar. This rare genetic disorder impairs other amino acid transport and protein synthesis, and can lead to seizures, vomiting, ketoacidosis, coma, and death if not treated with a low-branched chain amino acid diet and thiamine supplementation.
The document discusses several topics related to human reproductive cycles:
1. The ovarian cycle consists of the follicular and luteal phases, culminating in ovulation in the middle. The corpus luteum forms during the luteal phase and secretes hormones to prepare the uterus.
2. The menstrual cycle is controlled by ovarian hormones and has proliferative, secretory, and menstrual phases that regulate the endometrium.
3. Placentation begins with implantation and involves the formation of chorionic villi from the embryo and decidua from the endometrium to facilitate nutrient/waste exchange between mother and fetus without blood mixing. The placenta secretes important hormones throughout pregnancy.
1. Muscle tissue is one of four primary tissue types and is divided into three main categories: skeletal, cardiac, and smooth muscle. Skeletal muscle is attached to bones and allows voluntary movement.
2. Skeletal muscle contains bundles of fibers surrounded by connective tissues. Within the fibers are myofibrils composed of thin actin filaments and thick myosin filaments that slide past each other to cause muscle contraction.
3. Contraction is triggered when a motor neuron stimulates the neuromuscular junction, causing calcium release and the myosin heads to interact with and pull on the actin filaments. The strength of contraction depends on factors like overlap of filaments and stimulation frequency.
Compound lipids contain additional substances like phosphorus, carbohydrates or proteins in addition to fatty acids and alcohols. Phospholipids are important compound lipids that contain phosphoric acid and make up cell membranes. They are classified as glycerophospholipids containing glycerol or sphingophospholipids containing sphingosine. Glycolipids contain carbohydrate residues and sphingosine. Lipoproteins combine lipids and proteins and transport lipids in the bloodstream, classified by density.
oxidation of alpha, beta fatty acid and unsaturated fatty acid mariagul6
This document summarizes fatty acid oxidation through beta-oxidation. It discusses how fatty acids are broken down into acetyl-CoA in the mitochondria, generating energy in the form of ATP. Key points covered include the carnitine shuttle transport system, reactions of beta-oxidation, and oxidation of odd-chain and unsaturated fatty acids. Deficiencies in carnitine or the carnitine shuttle enzymes can impair fatty acid breakdown.
Homeostasis refers to the body's ability to maintain stable internal conditions and regulate physiological processes even when the external environment changes. All body systems work cooperatively through feedback mechanisms to sense changes and restore balance. For example, the cardiovascular system transports materials to cells while the respiratory system regulates gas exchange and pH. When a parameter like blood pressure rises, negative feedback loops bring it back down through effectors like the baroreceptors. This maintains stability and allows the body to function properly despite external fluctuations.
Subject : Nutrition, Unit- VI
This topic provides brief knowledge about lipid metabolism and it is prepared according to INC syllabus for first year BSc Nursing Students.
This document provides information about lipids. It defines lipids as compounds related more by physical properties than chemical properties that contain carbon, hydrogen, oxygen, and sometimes phosphorus, nitrogen, or sulfur. The document discusses the classification of lipids into simple, complex, and derived lipids. It provides details on the structure and function of important lipids like fatty acids, triglycerides, phospholipids, glycolipids, sterols, cholesterol, and eicosanoids. The document also outlines the biomedical importance of lipids in areas like energy storage, cell membrane structure, hormone production, and more.
The document discusses acylglycerols (AG), which are the major lipids in the body. Some key points:
- Phospholipids and sphingolipids are major lipid components of cell membranes and some have specialized functions like lung surfactant.
- Fatty acids can be incorporated into triacylglycerol for energy storage or into phospholipids to make membranes.
- Triacylglycerols (TAG) are biosynthesized through a three step process: 1) synthesis of glycerol phosphate, 2) conversion of fatty acids to an activated form, and 3) synthesis of TAG molecules from glycerol phosphate and fatty acyl CoA.
-
This document provides information about the digestion and absorption of carbohydrates and their clinical significance. It discusses how carbohydrates are digested by amylases in the mouth, stomach, and small intestine. Disaccharides are further broken down by disaccharidases in the small intestine. The monosaccharides glucose, fructose, and galactose are then absorbed into the bloodstream, primarily through sodium-dependent and sodium-independent glucose transporters. Clinical conditions like lactose intolerance result from deficiencies in disaccharidases like lactase. Overall, the document outlines the multi-step process of carbohydrate digestion and absorption and its implications for health.
Proteins are complex biomolecules composed of amino acids. They have four levels of structure: primary, secondary, tertiary, and quaternary. The primary structure is the linear sequence of amino acids. Secondary structure involves folding into shapes like alpha helices and beta sheets. Tertiary structure is the overall 3D shape of a single protein chain. Quaternary structure refers to the shape of proteins with multiple chains. Proteins are classified based on shape (globular or fibrous) and function (enzymes, hormones, etc.). They have various properties including solubility, hydrolysis, and denaturation.
These are major source of energy for living organisms.
Supplying a huge array of metabolic intermediates for biosynthetic reactions.
The structural elements in cell coat or connective tissues.
Carbohydrates are digested into monosaccharides like glucose, fructose, and galactose which are then absorbed in the small intestine. Glucose accounts for about 80% of absorbed monosaccharides and is actively transported into intestinal cells via sodium-glucose transporters, using the sodium gradient as an energy source. Galactose absorption is similar to glucose while fructose absorption occurs via facilitated diffusion without requiring sodium or energy. Absorption rates vary between sugars with galactose absorbing most rapidly, followed by glucose, then fructose and pentoses absorbing slowest. Health of the intestinal mucosa and various hormones can also impact carbohydrate absorption rates.
This document discusses the structure and function of nervous tissue. It begins by defining the basic components of nervous tissue: neurons, nerve processes (axons and dendrites), and neuroglia. It then describes in detail the anatomy and roles of neurons, glial cells like astrocytes and oligodendrocytes, myelination of axons, and synaptic transmission of nerve impulses between neurons. In summary, it provides an overview of the key cell types in the nervous system and how they enable neural signaling and communication.
Glycolysis (from glycose, an older term for glucose + -lysis degradation) is the metabolic pathway that converts glucose C6H12O6, into pyruvate, CH3COCOO− + H+. The free energy released in this process is used to form the high-energy molecules ATP (adenosine triphosphate) and NADH (reduced nicotinamide adenine ...
The urea cycle is a cyclic process that occurs primarily in the liver to convert toxic ammonia into urea for excretion. It involves 5 enzyme-catalyzed reactions, 3 in the mitochondria and 2 in the cytosol. The cycle uses 3 ATP and produces 1 molecule of urea while recycling ornithine. Defects in urea cycle enzymes can cause hyperammonemia, which can be toxic if ammonia levels rise and impair the tricarboxylic acid cycle in the brain. The presentation provided details on the individual reactions, regulation, energetics, disorders like hepatic coma, and inherited urea cycle defects.
The TCA cycle (also known as the Krebs cycle or citric acid cycle) is a series of chemical reactions in the mitochondria that breaks down acetyl-CoA molecules derived from carbohydrates, fats, and proteins into carbon dioxide. It is a cyclic process where oxaloacetate is regenerated at the end of each cycle. The cycle produces reduced electron carriers NADH and FADH2 that feed into the electron transport chain to generate ATP through oxidative phosphorylation. It is a central metabolic hub that connects several biochemical pathways and provides precursors for biosynthesis.
The document discusses carbohydrate metabolism, specifically glucose metabolism and the pathways involved in glucose oxidation and storage. It covers the following key points:
1) Glycolysis and the citric acid cycle are the two major pathways for glucose oxidation and energy production. Glycolysis occurs in the cytoplasm and citric acid cycle in the mitochondria.
2) Glycolysis converts glucose to pyruvate, producing a small amount of energy. Pyruvate can then enter the citric acid cycle or be converted to lactate.
3) The citric acid cycle further oxidizes acetyl groups from pyruvate, producing more energy through the electron transport chain.
Biological oxidation (part - III) Oxidative PhosphorylationAshok Katta
Biological oxidation (part - III) Oxidative Phosphorylation
- Mechanism of Oxidative Phosphorylation
-- Chemiosmotic theory
-P:O Ratio
Substrate Level Phosphorylation
Shuttle Systems for Oxidation of Extramitochondrial NADH
The document summarizes the process of muscle contraction via actin and myosin. Calcium ions are released which bind to troponin, displacing tropomyosin and exposing myosin binding sites on actin filaments. Myosin heads attach and change position to slide actin filaments, then detach when ATP binds. Hydrolysis of ATP provides energy to detach myosin heads, and calcium is reabsorbed allowing tropomyosin to reblock binding sites.
1. The document discusses the key nutrients required by the human body, including carbohydrates, fats, proteins, vitamins, minerals, water, and dietary fiber.
2. These nutrients are obtained from foods and are needed by the body for energy, growth, repair, health maintenance, and various metabolic functions.
3. A balanced diet containing foods from all the major groups in the right proportions is important for obtaining all the necessary nutrients and maintaining overall well-being.
The document discusses the structure and function of four main types of macromolecules - carbohydrates, nucleic acids, proteins, and lipids. It explains that carbohydrates include sugars and starches and are used for energy storage and structure. Nucleic acids like DNA and RNA contain genetic information and direct protein synthesis. Proteins have many functions including structure, movement, transport, and communication. Lipids compose cell membranes and are used for energy storage.
Metabolism of Brached Chain Amino Acid (Valine, Isoleucine, Leucine)Ashok Katta
Branched chain amino acids include leucine, isoleucine, and valine. They are broken down by the branched chain alpha-ketoacid dehydrogenase complex in mitochondria. A defect in this enzyme can cause branched chain ketoaciduria, where patients accumulate branched chain amino acids and their keto acids in their urine, which smells like maple syrup or burnt sugar. This rare genetic disorder impairs other amino acid transport and protein synthesis, and can lead to seizures, vomiting, ketoacidosis, coma, and death if not treated with a low-branched chain amino acid diet and thiamine supplementation.
The document discusses several topics related to human reproductive cycles:
1. The ovarian cycle consists of the follicular and luteal phases, culminating in ovulation in the middle. The corpus luteum forms during the luteal phase and secretes hormones to prepare the uterus.
2. The menstrual cycle is controlled by ovarian hormones and has proliferative, secretory, and menstrual phases that regulate the endometrium.
3. Placentation begins with implantation and involves the formation of chorionic villi from the embryo and decidua from the endometrium to facilitate nutrient/waste exchange between mother and fetus without blood mixing. The placenta secretes important hormones throughout pregnancy.
1. Muscle tissue is one of four primary tissue types and is divided into three main categories: skeletal, cardiac, and smooth muscle. Skeletal muscle is attached to bones and allows voluntary movement.
2. Skeletal muscle contains bundles of fibers surrounded by connective tissues. Within the fibers are myofibrils composed of thin actin filaments and thick myosin filaments that slide past each other to cause muscle contraction.
3. Contraction is triggered when a motor neuron stimulates the neuromuscular junction, causing calcium release and the myosin heads to interact with and pull on the actin filaments. The strength of contraction depends on factors like overlap of filaments and stimulation frequency.
Compound lipids contain additional substances like phosphorus, carbohydrates or proteins in addition to fatty acids and alcohols. Phospholipids are important compound lipids that contain phosphoric acid and make up cell membranes. They are classified as glycerophospholipids containing glycerol or sphingophospholipids containing sphingosine. Glycolipids contain carbohydrate residues and sphingosine. Lipoproteins combine lipids and proteins and transport lipids in the bloodstream, classified by density.
oxidation of alpha, beta fatty acid and unsaturated fatty acid mariagul6
This document summarizes fatty acid oxidation through beta-oxidation. It discusses how fatty acids are broken down into acetyl-CoA in the mitochondria, generating energy in the form of ATP. Key points covered include the carnitine shuttle transport system, reactions of beta-oxidation, and oxidation of odd-chain and unsaturated fatty acids. Deficiencies in carnitine or the carnitine shuttle enzymes can impair fatty acid breakdown.
Homeostasis refers to the body's ability to maintain stable internal conditions and regulate physiological processes even when the external environment changes. All body systems work cooperatively through feedback mechanisms to sense changes and restore balance. For example, the cardiovascular system transports materials to cells while the respiratory system regulates gas exchange and pH. When a parameter like blood pressure rises, negative feedback loops bring it back down through effectors like the baroreceptors. This maintains stability and allows the body to function properly despite external fluctuations.
Subject : Nutrition, Unit- VI
This topic provides brief knowledge about lipid metabolism and it is prepared according to INC syllabus for first year BSc Nursing Students.
This document provides information about lipids. It defines lipids as compounds related more by physical properties than chemical properties that contain carbon, hydrogen, oxygen, and sometimes phosphorus, nitrogen, or sulfur. The document discusses the classification of lipids into simple, complex, and derived lipids. It provides details on the structure and function of important lipids like fatty acids, triglycerides, phospholipids, glycolipids, sterols, cholesterol, and eicosanoids. The document also outlines the biomedical importance of lipids in areas like energy storage, cell membrane structure, hormone production, and more.
The document discusses acylglycerols (AG), which are the major lipids in the body. Some key points:
- Phospholipids and sphingolipids are major lipid components of cell membranes and some have specialized functions like lung surfactant.
- Fatty acids can be incorporated into triacylglycerol for energy storage or into phospholipids to make membranes.
- Triacylglycerols (TAG) are biosynthesized through a three step process: 1) synthesis of glycerol phosphate, 2) conversion of fatty acids to an activated form, and 3) synthesis of TAG molecules from glycerol phosphate and fatty acyl CoA.
-
This document provides information about the digestion and absorption of carbohydrates and their clinical significance. It discusses how carbohydrates are digested by amylases in the mouth, stomach, and small intestine. Disaccharides are further broken down by disaccharidases in the small intestine. The monosaccharides glucose, fructose, and galactose are then absorbed into the bloodstream, primarily through sodium-dependent and sodium-independent glucose transporters. Clinical conditions like lactose intolerance result from deficiencies in disaccharidases like lactase. Overall, the document outlines the multi-step process of carbohydrate digestion and absorption and its implications for health.
Proteins are complex biomolecules composed of amino acids. They have four levels of structure: primary, secondary, tertiary, and quaternary. The primary structure is the linear sequence of amino acids. Secondary structure involves folding into shapes like alpha helices and beta sheets. Tertiary structure is the overall 3D shape of a single protein chain. Quaternary structure refers to the shape of proteins with multiple chains. Proteins are classified based on shape (globular or fibrous) and function (enzymes, hormones, etc.). They have various properties including solubility, hydrolysis, and denaturation.
These are major source of energy for living organisms.
Supplying a huge array of metabolic intermediates for biosynthetic reactions.
The structural elements in cell coat or connective tissues.
Carbohydrates are digested into monosaccharides like glucose, fructose, and galactose which are then absorbed in the small intestine. Glucose accounts for about 80% of absorbed monosaccharides and is actively transported into intestinal cells via sodium-glucose transporters, using the sodium gradient as an energy source. Galactose absorption is similar to glucose while fructose absorption occurs via facilitated diffusion without requiring sodium or energy. Absorption rates vary between sugars with galactose absorbing most rapidly, followed by glucose, then fructose and pentoses absorbing slowest. Health of the intestinal mucosa and various hormones can also impact carbohydrate absorption rates.
This document discusses the structure and function of nervous tissue. It begins by defining the basic components of nervous tissue: neurons, nerve processes (axons and dendrites), and neuroglia. It then describes in detail the anatomy and roles of neurons, glial cells like astrocytes and oligodendrocytes, myelination of axons, and synaptic transmission of nerve impulses between neurons. In summary, it provides an overview of the key cell types in the nervous system and how they enable neural signaling and communication.
Glycolysis (from glycose, an older term for glucose + -lysis degradation) is the metabolic pathway that converts glucose C6H12O6, into pyruvate, CH3COCOO− + H+. The free energy released in this process is used to form the high-energy molecules ATP (adenosine triphosphate) and NADH (reduced nicotinamide adenine ...
The urea cycle is a cyclic process that occurs primarily in the liver to convert toxic ammonia into urea for excretion. It involves 5 enzyme-catalyzed reactions, 3 in the mitochondria and 2 in the cytosol. The cycle uses 3 ATP and produces 1 molecule of urea while recycling ornithine. Defects in urea cycle enzymes can cause hyperammonemia, which can be toxic if ammonia levels rise and impair the tricarboxylic acid cycle in the brain. The presentation provided details on the individual reactions, regulation, energetics, disorders like hepatic coma, and inherited urea cycle defects.
The TCA cycle (also known as the Krebs cycle or citric acid cycle) is a series of chemical reactions in the mitochondria that breaks down acetyl-CoA molecules derived from carbohydrates, fats, and proteins into carbon dioxide. It is a cyclic process where oxaloacetate is regenerated at the end of each cycle. The cycle produces reduced electron carriers NADH and FADH2 that feed into the electron transport chain to generate ATP through oxidative phosphorylation. It is a central metabolic hub that connects several biochemical pathways and provides precursors for biosynthesis.
The document discusses carbohydrate metabolism, specifically glucose metabolism and the pathways involved in glucose oxidation and storage. It covers the following key points:
1) Glycolysis and the citric acid cycle are the two major pathways for glucose oxidation and energy production. Glycolysis occurs in the cytoplasm and citric acid cycle in the mitochondria.
2) Glycolysis converts glucose to pyruvate, producing a small amount of energy. Pyruvate can then enter the citric acid cycle or be converted to lactate.
3) The citric acid cycle further oxidizes acetyl groups from pyruvate, producing more energy through the electron transport chain.
Biological oxidation (part - III) Oxidative PhosphorylationAshok Katta
Biological oxidation (part - III) Oxidative Phosphorylation
- Mechanism of Oxidative Phosphorylation
-- Chemiosmotic theory
-P:O Ratio
Substrate Level Phosphorylation
Shuttle Systems for Oxidation of Extramitochondrial NADH
The document summarizes the process of muscle contraction via actin and myosin. Calcium ions are released which bind to troponin, displacing tropomyosin and exposing myosin binding sites on actin filaments. Myosin heads attach and change position to slide actin filaments, then detach when ATP binds. Hydrolysis of ATP provides energy to detach myosin heads, and calcium is reabsorbed allowing tropomyosin to reblock binding sites.
1. The document discusses the key nutrients required by the human body, including carbohydrates, fats, proteins, vitamins, minerals, water, and dietary fiber.
2. These nutrients are obtained from foods and are needed by the body for energy, growth, repair, health maintenance, and various metabolic functions.
3. A balanced diet containing foods from all the major groups in the right proportions is important for obtaining all the necessary nutrients and maintaining overall well-being.
The document discusses the structure and function of four main types of macromolecules - carbohydrates, nucleic acids, proteins, and lipids. It explains that carbohydrates include sugars and starches and are used for energy storage and structure. Nucleic acids like DNA and RNA contain genetic information and direct protein synthesis. Proteins have many functions including structure, movement, transport, and communication. Lipids compose cell membranes and are used for energy storage.
The document describes the different levels of organization within organisms, from organelles to cells to tissues to organs to organ systems. It provides examples of structures at each level such as organelles including the nucleus, chloroplasts and mitochondria. Cells include skin cells, muscle cells and neurons. Tissues include muscle, nerves and blood. Organs include the heart, skin and brain. Organ systems include the circulatory, nervous and endocrine systems.
1. Organic compounds are made up of carbon along with hydrogen, oxygen, and sometimes nitrogen, phosphorus, and sulfur. They make up all living things.
2. Carbon can form chains and rings by bonding through single, double, or triple covalent bonds. Very large molecules called macromolecules are formed when many smaller molecules bond together.
3. Polymers are large molecules composed of many repeating smaller molecule units called monomers. They are formed through a process called dehydration synthesis which requires the removal of a water molecule.
- Biological molecules are organic and contain carbon, hydrogen, and oxygen. They include carbohydrates, lipids, proteins, and nucleic acids.
- Carbohydrates include simple sugars and complex starches and fibers. Lipids are made of fatty acids and glycerol. Proteins are made of amino acid chains. Nucleic acids like DNA and RNA are made of nucleotide chains.
- These molecules provide energy and materials for growth, with carbohydrates and lipids providing energy and proteins providing materials. They take part in hydrolysis and condensation reactions to break down and form other molecules.
Carbohydrates are compounds made of carbon, hydrogen, and oxygen. They provide our bodies with energy and come in three types: monosaccharides like glucose and fructose, disaccharides formed when two monosaccharides join, and polysaccharides consisting of many joined sugar units like starch, glycogen, and cellulose. Lipids are triglycerides composed of carbon, hydrogen, and oxygen that provide energy storage and hormone production. Proteins are polymers of amino acids that perform critical functions like oxygen transport and hormone messaging. Nucleic acids are information-storing polymers including DNA with bases of adenine, guanine, cytosine, and thymine, and RNA.
The document discusses biochemistry and the organization of cells. It begins by defining biochemistry as the study of chemical processes within living organisms, including metabolism, cell structure, signaling pathways, and genetic expression. It then describes the main categories of cells - prokaryotic and eukaryotic. Prokaryotic cells are simpler and lack a nucleus, while eukaryotic cells are more complex and have membrane-bound organelles. The document proceeds to describe key organelles such as the cell membrane, nucleus, mitochondria, endoplasmic reticulum, Golgi apparatus, lysosomes, and vacuoles. It concludes by discussing the importance of water as a solvent for biochemical reactions in the body.
All cells share similarities in their basic macromolecular components and chemical reactions. They all use nucleic acids like DNA and RNA to store and access genetic information. Proteins, which are polymers of amino acids, serve as enzymes to catalyze cellular reactions. Lipids form cellular membranes and carbohydrates serve structural and energy roles. The same condensation and hydrolysis reactions are used to form and break down these macromolecules in all organisms, reflecting their shared evolutionary origin.
BIOLOGY FORM 4 CHAPTER 4 - CHEMICAL COMPOSITION OF THE CELL PART 1Nirmala Josephine
Living organisms are composed of about 25 chemical elements, primarily carbon, hydrogen, oxygen, and nitrogen. These elements combine to form macromolecules like carbohydrates, lipids, proteins, and nucleic acids that make up living matter. Carbohydrates like starch and glycogen store glucose for energy. Lipids made of triglycerides provide over twice as much energy per gram when broken down. Proteins are needed to build new cells and tissues. Nucleic acids like DNA and RNA contain the genetic code and help synthesize proteins. Water is essential for life, making up over 70% of living things and enabling biochemical reactions and transport within organisms.
This document discusses biochemical molecules. It begins by explaining that all living organisms require biomolecules like organic and inorganic compounds. The four most common elements in living organisms are carbon, hydrogen, oxygen, and nitrogen. Biomolecules can be grouped as carbohydrates, lipids, proteins, nucleic acids, water, and minerals. Carbohydrates include monosaccharides, disaccharides, and polysaccharides. Lipids function as storage, structure, signaling, and pigments. Proteins are made of amino acids linked by peptide bonds that can fold into complex structures.
Biomolecules are organic or inorganic chemicals found in living organisms. Organic biomolecules include carbohydrates, lipids, proteins, and nucleic acids. Macromolecules like proteins, nucleic acids, and polysaccharides are formed by polymerization of monomers like amino acids, nucleotides, and monosaccharides. Proteins have primary, secondary, tertiary, and quaternary structures. Nucleic acids contain nitrogenous bases, sugars, and phosphates. Enzymes are protein biomolecules that catalyze metabolic reactions without being consumed. They have optimal pH, temperature, and substrate concentrations for maximum activity.
The document introduces the 7 classes of nutrients found in food, including carbohydrates. Carbohydrates are divided into monosaccharides, disaccharides, and polysaccharides. Starch, glycogen, and cellulose are discussed as examples. Starch is the most important source of carbohydrates and is found in plant foods. Glycogen acts as the storage form of carbohydrate in animals. Cellulose forms the bulk of plant cell walls but is not digestible by humans.
The document summarizes key biological molecules including carbohydrates, proteins, lipids, and nucleic acids. Carbohydrates include sugars, starches, and cellulose and can be monosaccharides, disaccharides, or polysaccharides. Proteins are made of amino acids joined by peptide bonds. Lipids include triglycerides and fats/oils. Nucleic acids DNA and RNA store and express genetic information through nucleotides of bases, sugars, and phosphates.
Organic molecules can be made of carbon, hydrogen, oxygen, and other elements. They include carbohydrates, lipids, proteins, and nucleic acids. Carbohydrates are sugars and starches made of carbon, hydrogen, and oxygen. The shape of a molecule determines its function. Amino acids are the building blocks of proteins. Cell membranes are made of a phospholipid bilayer and embedded proteins that control what passes through. DNA functions as the genetic material and RNA helps make proteins.
Organic molecules can be made of carbon, hydrogen, oxygen, and other elements. They include carbohydrates, lipids, proteins, and nucleic acids. Carbohydrates are sugars and starches made of carbon, hydrogen, and oxygen. The shape of a molecule determines its function. Amino acids are the building blocks of proteins. Cell membranes are made of a phospholipid bilayer and embedded proteins that control what passes through. DNA functions as the genetic material and RNA carries instructions from DNA.
This document provides an overview of biomolecules and their functions. It discusses that carbon compounds are the basis of organic molecules in living things. The four main biomolecules are carbohydrates, lipids, proteins, and nucleic acids. Carbohydrates, lipids, and proteins are used primarily as energy sources or building blocks, while nucleic acids like DNA and RNA store and transmit genetic information essential for life.
1. The document discusses the basic biological molecules - carbohydrates, lipids, proteins, and nucleic acids. It describes how each is made up of smaller monomer units that bond together to form larger polymers.
2. Carbohydrates include sugars, starch and cellulose. Lipids include fats, oils, and phospholipids. Proteins are made of amino acids linked by peptide bonds. Nucleic acids like DNA and RNA are made of nucleotides.
3. These molecules are the building blocks of life and perform important functions in organisms like energy storage, structure, catalysis and information transfer.
This document summarizes key concepts about carbohydrates, lipids, proteins, nucleic acids, and energy and living systems from Chapter 20. It discusses the structures and functions of monosaccharides, disaccharides, and polysaccharides. It also describes lipids, amino acids, proteins, enzymes, DNA, gene technology, photosynthesis, cellular respiration, and how ATP is used to do work in cells.
Introduction of biology (biology form 4)Merry Well
Biology is the scientific study of life and living organisms. It involves studying their structure, function, development, behavior, origin, and distribution. Biology aims to understand the importance and diversity of life forms through various fields of study including anatomy, physiology, ecology, and genetics. Biologists use the scientific method and employ scientific skills like observation and experimentation to make discoveries about living things and further our understanding of biology. Their work has many applications including improving human health, managing our environment, and advancing agriculture.
The simplified electron and muon model, Oscillating Spacetime: The Foundation...RitikBhardwaj56
Discover the Simplified Electron and Muon Model: A New Wave-Based Approach to Understanding Particles delves into a groundbreaking theory that presents electrons and muons as rotating soliton waves within oscillating spacetime. Geared towards students, researchers, and science buffs, this book breaks down complex ideas into simple explanations. It covers topics such as electron waves, temporal dynamics, and the implications of this model on particle physics. With clear illustrations and easy-to-follow explanations, readers will gain a new outlook on the universe's fundamental nature.
Physiology and chemistry of skin and pigmentation, hairs, scalp, lips and nail, Cleansing cream, Lotions, Face powders, Face packs, Lipsticks, Bath products, soaps and baby product,
Preparation and standardization of the following : Tonic, Bleaches, Dentifrices and Mouth washes & Tooth Pastes, Cosmetics for Nails.
it describes the bony anatomy including the femoral head , acetabulum, labrum . also discusses the capsule , ligaments . muscle that act on the hip joint and the range of motion are outlined. factors affecting hip joint stability and weight transmission through the joint are summarized.
How to Fix the Import Error in the Odoo 17Celine George
An import error occurs when a program fails to import a module or library, disrupting its execution. In languages like Python, this issue arises when the specified module cannot be found or accessed, hindering the program's functionality. Resolving import errors is crucial for maintaining smooth software operation and uninterrupted development processes.
Assessment and Planning in Educational technology.pptxKavitha Krishnan
In an education system, it is understood that assessment is only for the students, but on the other hand, the Assessment of teachers is also an important aspect of the education system that ensures teachers are providing high-quality instruction to students. The assessment process can be used to provide feedback and support for professional development, to inform decisions about teacher retention or promotion, or to evaluate teacher effectiveness for accountability purposes.
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ISO/IEC 27001, ISO/IEC 42001, and GDPR: Best Practices for Implementation and...PECB
Denis is a dynamic and results-driven Chief Information Officer (CIO) with a distinguished career spanning information systems analysis and technical project management. With a proven track record of spearheading the design and delivery of cutting-edge Information Management solutions, he has consistently elevated business operations, streamlined reporting functions, and maximized process efficiency.
Certified as an ISO/IEC 27001: Information Security Management Systems (ISMS) Lead Implementer, Data Protection Officer, and Cyber Risks Analyst, Denis brings a heightened focus on data security, privacy, and cyber resilience to every endeavor.
His expertise extends across a diverse spectrum of reporting, database, and web development applications, underpinned by an exceptional grasp of data storage and virtualization technologies. His proficiency in application testing, database administration, and data cleansing ensures seamless execution of complex projects.
What sets Denis apart is his comprehensive understanding of Business and Systems Analysis technologies, honed through involvement in all phases of the Software Development Lifecycle (SDLC). From meticulous requirements gathering to precise analysis, innovative design, rigorous development, thorough testing, and successful implementation, he has consistently delivered exceptional results.
Throughout his career, he has taken on multifaceted roles, from leading technical project management teams to owning solutions that drive operational excellence. His conscientious and proactive approach is unwavering, whether he is working independently or collaboratively within a team. His ability to connect with colleagues on a personal level underscores his commitment to fostering a harmonious and productive workplace environment.
Date: May 29, 2024
Tags: Information Security, ISO/IEC 27001, ISO/IEC 42001, Artificial Intelligence, GDPR
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How to Add Chatter in the odoo 17 ERP ModuleCeline George
In Odoo, the chatter is like a chat tool that helps you work together on records. You can leave notes and track things, making it easier to talk with your team and partners. Inside chatter, all communication history, activity, and changes will be displayed.
This presentation includes basic of PCOS their pathology and treatment and also Ayurveda correlation of PCOS and Ayurvedic line of treatment mentioned in classics.
Introduction to AI for Nonprofits with Tapp NetworkTechSoup
Dive into the world of AI! Experts Jon Hill and Tareq Monaur will guide you through AI's role in enhancing nonprofit websites and basic marketing strategies, making it easy to understand and apply.
Executive Directors Chat Leveraging AI for Diversity, Equity, and InclusionTechSoup
Let’s explore the intersection of technology and equity in the final session of our DEI series. Discover how AI tools, like ChatGPT, can be used to support and enhance your nonprofit's DEI initiatives. Participants will gain insights into practical AI applications and get tips for leveraging technology to advance their DEI goals.
A review of the growth of the Israel Genealogy Research Association Database Collection for the last 12 months. Our collection is now passed the 3 million mark and still growing. See which archives have contributed the most. See the different types of records we have, and which years have had records added. You can also see what we have for the future.
A workshop hosted by the South African Journal of Science aimed at postgraduate students and early career researchers with little or no experience in writing and publishing journal articles.
Macroeconomics- Movie Location
This will be used as part of your Personal Professional Portfolio once graded.
Objective:
Prepare a presentation or a paper using research, basic comparative analysis, data organization and application of economic information. You will make an informed assessment of an economic climate outside of the United States to accomplish an entertainment industry objective.
1. Examples
Function oF ElEmEnts in animal cElls and plant cElls
Elements Animal cells Plant cells
Carbon, Hydrogen,
Oxygen, Nitrogen
Synthesis of _____________________ compounds. For
example ________________________________________.
Synthesis of organic compounds. For example proteins, lipids
and nucleic acids.
Sulphur (S) Component of some _________________________. Component of some proteins.
Phosphorus (P)
Formation of bones and teeth. / _________________ of
muscles / synthesis _____________________
Induces the formation of flowers and _______________. /
Promotes cell division. / Synthesis of ATP and nucleic acids.
Sodium (Na)
Regulates _______________ pressure in the cells. / Helps in
the transmission of ___________________________.
Not Required.
Magnesium (Mg)
Involved in protein synthesis. / Act as a _________________
for some enzyme.
Required for the synthesis of _________________________. /
Activates enzymes in the cells.
Required for the formation of strong bones and teeth. /
Contraction of muscles cells / Promote blood clotting.
Synthesis of cell walls (________________________). /
Maintain the semi-permeability of plasma membrane.
Iron (Fe)
Synthesis of _________________ blood cells / Respiratory
enzymes.
Synthesis of _______________________. / Act as an electron
carrier during photosynthesis and respiration.
Required in muscle contractions and transmission of nerve
impulses.
Synthesis of carbohydrates. / Activates certain enzymes.
Chlorine (Cl)
Synthesis HCl by gastric glands in the stomach which destroys
pathogens and maintains ______________ of the stomach.
_______________________ of water during light reaction in
photosynthesis.
Substance composed of only one kind of atom which cannot be broken down
into simpler substances by chemical reactions.
Substance which consists of two or more elements combined in a fixed ratio.
Contain carbon and
hydrogen
Do not contain carbon
and hydrogen
2. Medium of __________________
reactions
-digestive reactions such as
breaking down of protein, lipids and
sugars.
High surface tension and ___________
(tent to stick each other)
-Water can move in long unbroken
columns through the vascular tissue in
plants.
Water
The
importance of
water in the
cell
________ %
of our body A polar molecules consists
of two _____________
atom dan one
_____________ atom.
Present in
Structure
___________________
-can dissolve many ionic
compounds such as salt and
polar molecules (sugar)
__________________ Medium
-in the blood, lymphatic,
excretory & digestive system
(transport sugar O2, CO2)
Maintain __________________
balance and ______________
-maintain the stable internal
environment within a living
organism.
____________________
-support the structure of a cell
(90% of the protoplasm is made
up of water)
Maintain ___________________
____________ and _______________
-Provides moisture to respiratory
surfaces (alveoli)
-Mucus assist the movement of food
substances in the intestinal tract.
3. Nucleic Acids
are
2 types
structure structure
function function
Basic
units
Draw the structure
functions
Complex
macromolecules
which store _______
_________________
in the form of code.
• A __________-stranded nucleic
acid, with the two strands of
polynucleotides twisted around
each other to form a
_________________________
• Found in nucleus of a cell.
• Genetic material that
organisms ____________ from
their parents.
• Store information regarding its
own replication and the order in
which amino acids are linked to
make a protein.
• ____________ - stranded
nucleic acid.
• Found in the cytoplasm,
ribosomes and nucleus.
• _________________________
carries DNA’s genetic code into
the cytoplasm and directs the
synthesis of proteins.
4. Protein Main
function
Elements
2 X
Equation
Long chain
2 types
Plant proteinAnimal protein
2 classes
Structure
• Amino acids that cannot
be synthesised by the
body.
• Can only be obtained
from a healthy diet.
• Amino acids that
can be synthesised
by the body.
(contain all the essential
amino acids)
(do not contain all the
essential amino acids)
• Linear sequence of amino acids
in a polypeptide chain
• Polypeptide chain that is coiled
to form alpha-helix or folded into
beta-pleated.
• The helix chains or beta-pleated
sheets are folded into a 3D
shape of polypeptide chain.
• Hormones, enzymes, plasma
protein, antibodies
• Two or more tertiary structure
polypeptide chains are arranged
to form a large and complex
protein molecule.
monomer
5. Carbohydrates
Elements Main function
• Simple sugar
• C6H12O6
• combine with
proteins and lipids to
form ________ &
______ respectively
characteristics characteristics characteristics
3 types
3 types 3 types
Genaral Equation
3 typesEquation
• _______________ sugar /
complex sugars.
• Consists of 2 _____________
joined together through
condensation
Sucrose
• Hundreds or thousands of
monosaccharides linked through
_________________ to form a long
chain of molecules.
• ___________________ in water
• Do not taste sweet.
• Do not crystallise.
6. Lipids Main
function
Elements
Fats Oils
Main component of
plasma membrane
Fatty acids
Equation
plant
animal
structure
5 main types
_________ at
room temperature
___________ at
room temperature
Long chain
molecules / water
proof.
• Found on the
____________ of the
epidermis of leaves,
fruits and seeds of
some plants.
• ____________ that is
excreted from oil
glands in the skin
contains wax that
soften the skin.
Major component in plasma
membrane.
Male sex hormone.
Female sex hormones.
7. The Differences between saturated fats and
unsaturated fats
Saturated Fats Differences Unsaturated Fats
The presence of
double bonds
between carbon
atoms in fatty acids
Ability to react with an
additional hydrogen
atom
Condition at room
temperature
Cholesterol level
Examples
9. Element
Compound
Examples
Function of Elements in animal cells and plant cells
Elements Animal cells Plant cells
C, H, O, N
Synthesis of organic compounds. For example proteins, lipids
and nucleic acids
S Component of some proteins
P
Formation of bones and teeth. / Contraction of muscles /
synthesis ATP
Induces the formation of flowers and seeds. / Promotes cell
division. / Synthesis of ATP and nucleic acids.
Na
Regulates osmotic pressure in the cells. / Helps in the
transmission of nerve impulses.
Not Required
Mg
Involved in protein synthesis. / Act as a cofactor for some
enzyme.
Required for the synthesis of chlorophyll. / Activates enzymes
in the cells.
Ca
Required for the formation of strong bones and teeth. /
Contraction of muscles cells / Promote blood clotting.
Synthesis of cell walls (Cellulose). / Maintain the semi-
permeability of plasma membrane.
Fe Synthesis of red blood cells / Respiratory enzymes.
Synthesis of chlorophyll. / Act as an electron carrier during
photosynthesis and respiration.
K
Required in muscle contractions and transmission of nerve
impulses.
Synthesis of carbohydrates. / Activates certain enzymes.
Cl
Synthesis HCl by gastric glands in the stomach which destroys
pathogens and maintains pH of the stomach.
Photolysis of water during light reaction in photosynthesis.
Substance composed of only one kind of atom which cannot be broken down
into simpler substances by chemical reactions.
Substance which consists of two or more elements combined in a fixed ratio.
Organic compounds
Inorganic compounds
Contain carbon
Not contain carbon
Carbohydrates, proteins,
lipids, nucleic acids
Water
10. High surface tension and cohesion
(tent to stick each other)
-Water can move in long unbroken
columns through the vascular
tissue in plants.
Water
The
importance of
water in the
cell
70-90% of our
body
A polar molecules
consists of 2
hidrogen atom & 1
oxygen atomPresent in
Structure
Cell, lymph, blood plasma
and interstitial fluid.
Medium of biochemical reactions
-digestive reactions such as
breaking down of protein, lipids
and sugars.
Solvent
-can dissolve many ionic
compounds such as salt and
polar molecules (sugar)
Transport Medium
-in the blood, lymphatic,
excretory & digestive system
(transport sugar O2, CO2)
Maintain osmotic balance and
turgidity
-maintain the stable internal
environment within a living
organism.
Support
-support the structure of a cell
(90% of the protoplasm is made
up of water)
Maintain body temperature
Moisture and lubrication
-Provides moisture to respiratory
surfaces (alveoli)
-Mucus assist the movement of
food substances in the intestinal
tract.
11. Nucleic Acids
are
DNA RNA
2 types
structure structure
function function
Basic
units
structure
functions
Complex
macromolecules which
store genetic
information in the form
of code.
nucleotides
• A double-stranded nucleic acid,
with the two strands of
polynucleotides twisted around
each other to form a double
helix.
• Found in nucleus of a cell.
• Genetic material that
organisms inherit from their
parents.
• Store information regarding its
own replication and the order in
which amino acids are linked to
make a protein.
• Single-stranded nucleic acid.
• Found in the cytoplasm,
ribosomes and its nucleus.
• Messenger RNA carries DNA’s
genetic code into the cytoplasm
and directs the synthesis of
proteins.
• Transmission of
genetic
information.
• Store genetic
information
12. Protein
Main
function
Elements
Amino acids
2 X
equation
Long chain
2 types
Plant proteinAnimal protein
2 classes
Structure
Carbon, hydrogen, oxygen,
nitrogen. Most proteins also
contain sulphur and
phosphorus.
dipeptide
polypeptide
Essential amino
acids (20)
Non-essential
amino acids (11)
• Amino acids that
cannot be
synthesised by the
body.
• Can only be obtained
from a healthy diet.
• Amino acids that can
be synthesised by
the body.
First class protein
(contain all the essential
amino acids)
Second class protein
(do not contain all the
essential amino acids)
• Linear sequence of amino acids
in a polypeptide chain
• Polypeptide chain that is coiled
to form alpha-helix or folded into
beta-pleated.
• The helix chains or beta-pleated
sheets are folded into a 3D
shape of polypeptide chain.
• Hormones, enzymes, plasma
protein, antibodies
• Two or more tertiary structure
polypeptide chains are arranged
to form a large and complex
protein molecule.
Build new cells for growth
and renew damaged tissues
and store energy.
13. Carbohydrates
Elements
Main
function
• Simple sugar
• C6H12O6
• combine with
proteins and lipids to
form ________ &
______ respectively
characteristics characteristics characteristics
3 types
3 types 3 types
formula
3 typesEquation
Carbon, hydrogen
and oxygen.
Ratio of H and O is
2 : 1
• Glucose (grape sugar)
• Fructose (in fruits / honey)
• Galactose (in milk)
• Double sugar / complex
sugars.
• Consists of 2
monosaccharides joined
together through
condensation
Sucrose
• Hundreds or thousands of
monosaccharides linked through
condensation to form a long chain
of molecules.
• Insoluble in water
• Do not taste sweet.
• Do not crystallise.
14. Lipids
Main
function
Elements
Fats Oils Waxes Steroids
Main component of
plasma membrane
Fatty acids
Equation
plant
animal
structure
Cholesterol
Testosterone
Oestrogen, progesteron
5 main types
Carbon, hydrogen and
oxygen.
Solid at room
temperature
liquid at room
temperature
Long chain
molecules / water
proof.
• Found on the cuticles
of the epidermis of
leaves, fruits and
seeds of some plants.
• Sebum that is
excreted from oil
glands in the skin
contains wax that
soften the skin.
Source of energy
and energy
storage.
Major component in plasma
membrane.
Male sex hormone.
Female sex hormones.
15. The Differences between saturated fats and
unsaturated fats
Saturated Fats Differences Unsaturated Fats
• Do not have any double bonds.
The presence of
double bonds
between carbon
atoms in fatty acids
• Have at least one double bond
between the carbon atoms.
• Cannot form any chemical bonds with
other atoms or react with additional
hydrogen atoms.
Ability to react with
an additional
hydrogen atom
• Able to react with additional
hydrogen atoms. (with one double
bond are called monounsaturated
fats)
• Solid Condition at room
temperature
• Liquid
• Contain more cholesterol. Cholesterol level • Contain less cholesterol
• Animal fats like butter
Examples
• Vegetable oils like corn oil and palm
oil.