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Movement of
substances across
the plasma
membrane
Chapter 3
• Many biochemical reactions take
place in a cell.
• The cells require many substances
to carry out these biochemical
reaction.
• Waste products that are formed
during biochemical reactions within
the cells must be eliminated
because they are poisonous.
• There is movement of substances across
the plasma membrane so that the cell can
Obtain nutrients and gases
Excrete metabolic wastes
Maintain a suitable pH and
ionic concentration with the
cell for enzyme activity
Red Blood Cell Near Some Body cell
Moving in Moving out
Carbon dioxide
Oxygen
Photosyntesising Plant Cell
Moving in Moving out
Carbon dioxide
Oxygen
Water
Glucose
Plant Cell With No Chloroplast
Carbon dioxide
Oxygen
Glucose
Water
Moving in Moving out
Liver cellCarbon dioxide
Oxygen
Glucose
Water
Amino acids
Urea
Moving in Moving out
The structure of the plasma membrane
The plasma
membrane has 3
components
1. Double layer of
phospholipids
molecules.
2. Pore
3. Carrier Proteins
A phospholipid molecule
Hydrophilic head
Hydrophobic tails
Phospholipid
bilayer
Outside of cell
Inside of cell Phospholipidlayer
• The phospholipids bilayer, proteins and other
parts are not rigid or static, but form a dynamic
and flexible structure.
• The protein molecules float about in the
phospholipid bilayer to form a mosaic pattern
that is always changing like fluid.
• Singer and Nicolson call it ‘fluid-mosaic model’
The plasma membrane is generally described as
semi-permeable or selectively permeable
because it only lets certain substances through.
Fat soluble molecules and
small molecules such as oxygen
are able to pass through unaided.
Water soluble substances such as
glucose and amino acids and ions
need to aided by carrier protein.
Water molecules can move
across plasma membrane.
Which of these substances can pass
through phospholipids layer or carrier
protein?
Na+ Sodium
ion
K+ Potassium
ion
Carrier
Protein
Channel
Protein
Movement Of Substances Across
The Plasma Membrane
Passive transport Active transport
Simple
diffusion
Facilitated
diffusion
Osmosis
The differences between PT and AT
Does not require
energy
Substances move
with concentration
gradient
Will continue until
an equilibrium is
reached
Require energy
from cell respiration
Substances move
against concentration
gradient
Process leads to
accumulation or
elimination of the
substance from the cell
Passive Transport Active Transport
Active TransportActive Transport
• The movement of particles across the plasma
membrane against the concentration
gradient, that is from a region of low
concentration to a region of high concentration.
• Active transport also requires specific carrier
proteins that bind to the substance to be
transported, enabling the substance to pass
rapidly across the plasma membrane.
• Sometimes the carrier proteins are referred to
biological pumps.
• Active transport requires an input of energy
provided by ATP. So, it can only take place in
living organism.
Sodium-potassium pumpSodium-potassium pump
Ion intake by root
hairs of a plant
Mineral ions are absorbed across the membranes of the root
hairs by active transport.
Facilitated DiffusionFacilitated Diffusion
• The movement of hydrophilic molecules or
ions across the plasma membrane with
the help of transport proteins.
• Substances that are not soluble in lipids
do not pass readily through the
phospholipid bilayer.
• Substances such as glucose, amino
acids, proteins and nucleic acids pass
through the membrane by facilitated
diffusion.
Facilitated Diffusion
Involves 2 types of protein
Channel proteins Carrier proteins
Provide functional pore in the
membrane for the diffusion of ions.
The pore are selective about which
ions can pass through
Pick up the diffusion molecules on
one side of the membrane and
release them on the other side
Absorption of certain nutrients through the villi of the small
intestine.
Carrier proteins found on the membrane of cells that line
the intestinal wall transport small molecules such as amino
acids and glucose into the blood capillaries of the villi
glucose
Ammino
acids
OsmosisOsmosis
The movement of water molecules from region of
their higher concentration to a region of their lower
concentration through a semi-permeable
membrane.
The water potential of a solution is a measure of
the tendency of water molecules to leave the
solution.
A dilute solution has a higher water potential than
a concentrated solution.
Therefore, water molecules flow from the dilute
solution to the concentrated solution.
How osmosis helps in the uptake of
water in plants?
Simple DiffusionSimple Diffusion
• The movement of particles (molecules or
solutes) within a gas or a liquid from a region of
high concentration to a region of lower
concentration.
Factors affecting the rate of difussion:
1. Surface area between the two region.
(The larger the surface are, the higher
the rate of diffusion)
2. Distance over which diffusion occurs.
(The shorter the distance over which
diffusion occurs, the higher the rate of
diffusion across it)
3. Concentration gradient.
(The greater the difference in concentration
between the two region, the higher the rate of
diffusion)
4. Size and nature of the particles.
(Smaller particles diffuse faster than larger
particles)
5. Temperature
(At higher temperatures, the particles have more
kinetic energy and so they diffuse at a higher
rate)
• Diffusion of different types of particle can
take place in opposite direction. For exp,
O2
O2
CO2
CO2
When oxygen diffuses
in of the cell, at the
same time carbon
dioxide diffuses out.
• Diffusion occurs in living and non living
systems.

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CHAPTER 3: MOVEMENT OF SUBSTANCES ACROSS THE PLASMA MEMBRANE

  • 1. Movement of substances across the plasma membrane Chapter 3
  • 2. • Many biochemical reactions take place in a cell. • The cells require many substances to carry out these biochemical reaction. • Waste products that are formed during biochemical reactions within the cells must be eliminated because they are poisonous.
  • 3. • There is movement of substances across the plasma membrane so that the cell can Obtain nutrients and gases Excrete metabolic wastes Maintain a suitable pH and ionic concentration with the cell for enzyme activity
  • 4. Red Blood Cell Near Some Body cell Moving in Moving out Carbon dioxide Oxygen
  • 5. Photosyntesising Plant Cell Moving in Moving out Carbon dioxide Oxygen Water Glucose
  • 6. Plant Cell With No Chloroplast Carbon dioxide Oxygen Glucose Water Moving in Moving out
  • 7. Liver cellCarbon dioxide Oxygen Glucose Water Amino acids Urea Moving in Moving out
  • 8. The structure of the plasma membrane The plasma membrane has 3 components 1. Double layer of phospholipids molecules. 2. Pore 3. Carrier Proteins
  • 9.
  • 10. A phospholipid molecule Hydrophilic head Hydrophobic tails
  • 11. Phospholipid bilayer Outside of cell Inside of cell Phospholipidlayer
  • 12. • The phospholipids bilayer, proteins and other parts are not rigid or static, but form a dynamic and flexible structure. • The protein molecules float about in the phospholipid bilayer to form a mosaic pattern that is always changing like fluid. • Singer and Nicolson call it ‘fluid-mosaic model’
  • 13. The plasma membrane is generally described as semi-permeable or selectively permeable because it only lets certain substances through. Fat soluble molecules and small molecules such as oxygen are able to pass through unaided. Water soluble substances such as glucose and amino acids and ions need to aided by carrier protein. Water molecules can move across plasma membrane.
  • 14. Which of these substances can pass through phospholipids layer or carrier protein? Na+ Sodium ion K+ Potassium ion Carrier Protein Channel Protein
  • 15. Movement Of Substances Across The Plasma Membrane Passive transport Active transport Simple diffusion Facilitated diffusion Osmosis
  • 16.
  • 17. The differences between PT and AT Does not require energy Substances move with concentration gradient Will continue until an equilibrium is reached Require energy from cell respiration Substances move against concentration gradient Process leads to accumulation or elimination of the substance from the cell Passive Transport Active Transport
  • 18. Active TransportActive Transport • The movement of particles across the plasma membrane against the concentration gradient, that is from a region of low concentration to a region of high concentration.
  • 19. • Active transport also requires specific carrier proteins that bind to the substance to be transported, enabling the substance to pass rapidly across the plasma membrane. • Sometimes the carrier proteins are referred to biological pumps. • Active transport requires an input of energy provided by ATP. So, it can only take place in living organism.
  • 21. Ion intake by root hairs of a plant Mineral ions are absorbed across the membranes of the root hairs by active transport.
  • 22. Facilitated DiffusionFacilitated Diffusion • The movement of hydrophilic molecules or ions across the plasma membrane with the help of transport proteins.
  • 23. • Substances that are not soluble in lipids do not pass readily through the phospholipid bilayer. • Substances such as glucose, amino acids, proteins and nucleic acids pass through the membrane by facilitated diffusion.
  • 24. Facilitated Diffusion Involves 2 types of protein Channel proteins Carrier proteins Provide functional pore in the membrane for the diffusion of ions. The pore are selective about which ions can pass through Pick up the diffusion molecules on one side of the membrane and release them on the other side
  • 25. Absorption of certain nutrients through the villi of the small intestine. Carrier proteins found on the membrane of cells that line the intestinal wall transport small molecules such as amino acids and glucose into the blood capillaries of the villi glucose Ammino acids
  • 26. OsmosisOsmosis The movement of water molecules from region of their higher concentration to a region of their lower concentration through a semi-permeable membrane.
  • 27. The water potential of a solution is a measure of the tendency of water molecules to leave the solution. A dilute solution has a higher water potential than a concentrated solution. Therefore, water molecules flow from the dilute solution to the concentrated solution.
  • 28.
  • 29.
  • 30. How osmosis helps in the uptake of water in plants?
  • 31. Simple DiffusionSimple Diffusion • The movement of particles (molecules or solutes) within a gas or a liquid from a region of high concentration to a region of lower concentration.
  • 32. Factors affecting the rate of difussion: 1. Surface area between the two region. (The larger the surface are, the higher the rate of diffusion) 2. Distance over which diffusion occurs. (The shorter the distance over which diffusion occurs, the higher the rate of diffusion across it)
  • 33. 3. Concentration gradient. (The greater the difference in concentration between the two region, the higher the rate of diffusion) 4. Size and nature of the particles. (Smaller particles diffuse faster than larger particles) 5. Temperature (At higher temperatures, the particles have more kinetic energy and so they diffuse at a higher rate)
  • 34. • Diffusion of different types of particle can take place in opposite direction. For exp, O2 O2 CO2 CO2 When oxygen diffuses in of the cell, at the same time carbon dioxide diffuses out. • Diffusion occurs in living and non living systems.