This document provides an overview of carcinoma of the thyroid gland, including epidemiology, causes and risk factors, classification, clinical presentation, diagnosis, and management. Some key points are: - Papillary carcinoma is the most common type, accounting for around 80% of cases. - Risk factors include radiation exposure, family history, and chronic iodine deficiency. - Clinical presentation varies depending on the type but commonly includes a solitary thyroid nodule or enlarged cervical lymph nodes. - Diagnosis involves laboratory tests, imaging like ultrasound, and fine needle aspiration biopsy. - Treatment options include surgery, radioactive iodine therapy, chemotherapy, and thyroid hormone replacement therapy.

1. CARCINOMA OF THYROID GLAND Dr. Ahmed Mirza Al-Shammasi 2031040009 Surgical Intern – KFU – Saudi Arabia

11. Thyroid Neoplasm Benign Malignant Secondary Primary Follicular Papillary Follicular Cells Parafollicular Cells Lymphoid Cells Lymphoma Medullary Differentiated Undifferentiated Anaplastic Follicular Papillary Hurthle Cell

46. PROGNOSIS Tumor Prognosis Papillary Ca. 74-93% long-term survival rate Follicular Ca. 43-94% long-term survival rate Hurthle Cell Ca. 20% mortality rate at 10 years Medullary Ca. 80% 10-year survival rate 45% with LN involvement Anaplastic Tumor Median survival of 4 to 5 months at time of diagnosis

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