Glandular hypomastia, or inadequate breast development, can be caused by developmental factors, genetic conditions like Poland syndrome, or weight loss/breastfeeding after childbirth. It affects women's self-esteem and quality of life. Breast augmentation surgery aims to increase volume and improve shape/symmetry by creating a pocket and inserting an implant. Common complications include infection, malposition, capsular contracture (scar tissue formation), rippling, implant rupture, and rare cases of breast implant-associated lymphoma. Close monitoring and additional surgery may be needed to address complications. Informed consent is important given women's health concerns regarding implants.
While many women desire round, lifted, and proportionate breasts, pregnancy, weight loss or gain, heredity, and age, can affect these goals. Breast augmentation, also known as breast enhancement or breast enlargement, allows a woman to increase the size of her breasts. Implants filled with silicone or saline can provide balance to their figure, while feeling surprisingly natural.
Breast Reduction Surgery (mammaplasty) in Kolkata | Dr Jayanta Kumar SahaCosmetic-Therapy Clinic
Reduction mammaplasty is the surgical procedure which is performed to reduce, reshape and tighten the size of excessively large female breast. Patients opt for reduction mammaplasty or breast reduction surgery in order to overcome the physical, sexual and social embarrassment attached with the problem. Dr. Jayanta Kumar Saha of Cosmetic Therapy Clinic, Kolkata is an expert cosmetic plastic surgeon who performs this procedure with great perfection and expertise. Consult him over phone or email him to seek advice on female breast reduction surgery and any other cosmetic surgery performed in his cosmetic therapy clinic in Kolkata. Chek here for more details: http://www.cosmetic-therapy.com/cosmetic-surgeries/surgeries-for-female/breast-reduction-surgery/
While many women desire round, lifted, and proportionate breasts, pregnancy, weight loss or gain, heredity, and age, can affect these goals. Breast augmentation, also known as breast enhancement or breast enlargement, allows a woman to increase the size of her breasts. Implants filled with silicone or saline can provide balance to their figure, while feeling surprisingly natural.
Breast Reduction Surgery (mammaplasty) in Kolkata | Dr Jayanta Kumar SahaCosmetic-Therapy Clinic
Reduction mammaplasty is the surgical procedure which is performed to reduce, reshape and tighten the size of excessively large female breast. Patients opt for reduction mammaplasty or breast reduction surgery in order to overcome the physical, sexual and social embarrassment attached with the problem. Dr. Jayanta Kumar Saha of Cosmetic Therapy Clinic, Kolkata is an expert cosmetic plastic surgeon who performs this procedure with great perfection and expertise. Consult him over phone or email him to seek advice on female breast reduction surgery and any other cosmetic surgery performed in his cosmetic therapy clinic in Kolkata. Chek here for more details: http://www.cosmetic-therapy.com/cosmetic-surgeries/surgeries-for-female/breast-reduction-surgery/
Abdominoplasty or tummy tuck surgery in Dubai is the most demanded procedure that removes excess deposit of fat across the belly. Contact Dr. Luiz Toledo at +971 (0)55-702-2780.
https://luiztoledo.com/procedures/abdominoplasty/
New Developments in Breast Reconstruction Surgerybkling
Deborah Axelrod, MD, of NYU Langone Perlmutter Cancer Center, and Rachel Bluebond-Langner, MD, of NYU Langone Medical Center discuss the latest research in autologous breast reconstruction, fat injection, pre-pectoral implants, and oncoplastic surgery.
Disclaimer: Graphic medical imagery.
Oncoplastic Breast surgery is simultaneous application of lumpectomy and reconstructive techniques. The word ‘oncoplastic’ is derived from the Greek words ‘onco’ (tumour) and ‘plastic’ (to mould).
Approximately 10% to 30% of patients submitted to BCS alone are not satisfied with the aesthetic outcomes like “swan beak/ parrot beak deformities. The main reasons are related this is the tumour resection which can produce asymmetry, retraction, and volume changes in the breast.
Recently, increasing attention has been focused on oncoplastic procedures since the immediate application of plastic breast surgery techniques provide a wider local excision while still achieving the goals of a better breast shape and symmetry to obtain oncologically sound and aesthetically pleasing results. Thus, by means of customized techniques the surgeon ensures that oncologic principles are not jeopardized while meeting the needs of the patient from an aesthetic point of view.
Best facial cosmetic surgeons Best facial plastic surgeon Browlift Charlotte endoscopic brow lift Charlotte’s top facial plastic surgeon Facial plastic surgeons Facial plastic surgery Face lifts Facial mini-tuck Lip enhancement Lip augmentation Nose job Nose job cost Nose surgery Rhinoplasty Rhinoplasty Expert Rhinoplasty and teens Revision rhinoplasty Teen Rhinoplasty, Charlotte Teen Rhinoplasty, North Carolina Teen Rhinoplasty Expert Top rhinoplasty surgeons Best Charlotte rhinoplasty surgeons Most experienced rhinoplasty surgeons
Abdominoplasty or tummy tuck surgery in Dubai is the most demanded procedure that removes excess deposit of fat across the belly. Contact Dr. Luiz Toledo at +971 (0)55-702-2780.
https://luiztoledo.com/procedures/abdominoplasty/
New Developments in Breast Reconstruction Surgerybkling
Deborah Axelrod, MD, of NYU Langone Perlmutter Cancer Center, and Rachel Bluebond-Langner, MD, of NYU Langone Medical Center discuss the latest research in autologous breast reconstruction, fat injection, pre-pectoral implants, and oncoplastic surgery.
Disclaimer: Graphic medical imagery.
Oncoplastic Breast surgery is simultaneous application of lumpectomy and reconstructive techniques. The word ‘oncoplastic’ is derived from the Greek words ‘onco’ (tumour) and ‘plastic’ (to mould).
Approximately 10% to 30% of patients submitted to BCS alone are not satisfied with the aesthetic outcomes like “swan beak/ parrot beak deformities. The main reasons are related this is the tumour resection which can produce asymmetry, retraction, and volume changes in the breast.
Recently, increasing attention has been focused on oncoplastic procedures since the immediate application of plastic breast surgery techniques provide a wider local excision while still achieving the goals of a better breast shape and symmetry to obtain oncologically sound and aesthetically pleasing results. Thus, by means of customized techniques the surgeon ensures that oncologic principles are not jeopardized while meeting the needs of the patient from an aesthetic point of view.
Best facial cosmetic surgeons Best facial plastic surgeon Browlift Charlotte endoscopic brow lift Charlotte’s top facial plastic surgeon Facial plastic surgeons Facial plastic surgery Face lifts Facial mini-tuck Lip enhancement Lip augmentation Nose job Nose job cost Nose surgery Rhinoplasty Rhinoplasty Expert Rhinoplasty and teens Revision rhinoplasty Teen Rhinoplasty, Charlotte Teen Rhinoplasty, North Carolina Teen Rhinoplasty Expert Top rhinoplasty surgeons Best Charlotte rhinoplasty surgeons Most experienced rhinoplasty surgeons
USMLE ENDOCRINE 04 Mammary glands breast ANATOMY MEDICAL .pdfAHMED ASHOUR
Surgery plays a crucial role in the management of various breast conditions, including both benign and malignant disorders. Understanding the surgical options for breast conditions is essential for breast surgeons, oncologists, and other healthcare professionals involved in breast care.
The choice of surgery depends on the specific diagnosis, patient preferences, and the overall treatment plan.
Surgical interventions aim to address the underlying condition, restore aesthetics when relevant, and contribute to the overall well-being of individuals with breast-related health concerns.
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
CDSCO and Phamacovigilance {Regulatory body in India}NEHA GUPTA
The Central Drugs Standard Control Organization (CDSCO) is India's national regulatory body for pharmaceuticals and medical devices. Operating under the Directorate General of Health Services, Ministry of Health & Family Welfare, Government of India, the CDSCO is responsible for approving new drugs, conducting clinical trials, setting standards for drugs, controlling the quality of imported drugs, and coordinating the activities of State Drug Control Organizations by providing expert advice.
Pharmacovigilance, on the other hand, is the science and activities related to the detection, assessment, understanding, and prevention of adverse effects or any other drug-related problems. The primary aim of pharmacovigilance is to ensure the safety and efficacy of medicines, thereby protecting public health.
In India, pharmacovigilance activities are monitored by the Pharmacovigilance Programme of India (PvPI), which works closely with CDSCO to collect, analyze, and act upon data regarding adverse drug reactions (ADRs). Together, they play a critical role in ensuring that the benefits of drugs outweigh their risks, maintaining high standards of patient safety, and promoting the rational use of medicines.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Adv. biopharm. APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMSAkankshaAshtankar
MIP 201T & MPH 202T
ADVANCED BIOPHARMACEUTICS & PHARMACOKINETICS : UNIT 5
APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMS By - AKANKSHA ASHTANKAR
Basavarajeeyam is an important text for ayurvedic physician belonging to andhra pradehs. It is a popular compendium in various parts of our country as well as in andhra pradesh. The content of the text was presented in sanskrit and telugu language (Bilingual). One of the most famous book in ayurvedic pharmaceutics and therapeutics. This book contains 25 chapters called as prakaranas. Many rasaoushadis were explained, pioneer of dhatu druti, nadi pareeksha, mutra pareeksha etc. Belongs to the period of 15-16 century. New diseases like upadamsha, phiranga rogas are explained.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Basavarajeeyam is a Sreshta Sangraha grantha (Compiled book ), written by Neelkanta kotturu Basavaraja Virachita. It contains 25 Prakaranas, First 24 Chapters related to Rogas& 25th to Rasadravyas.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
- Video recording of this lecture in English language: https://youtu.be/kqbnxVAZs-0
- Video recording of this lecture in Arabic language: https://youtu.be/SINlygW1Mpc
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
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Breast augmentation complications
1.
2. Glandular hypomastia may be
1- a developmental (primary)
2-a sequela of thoracic hypoplasia
(Poland syndrome) or other chest wall deformity
3- involutional process develop in the postpartum setting
and may be exacerbated by breast-feeding or significant
weight loss
3.
4. affects a significant number
of women in the United
States.
a negative body image.
feelings of inadequacy.
Low self-esteem .
adversely affect a patient’s
interpersonal relationships,
sexual fulfillment, and
quality of life
6. Augmentation
mammaplasty is an aesthetic
procedure designed to increase
the volume and size of the
breast , other surgical goals
include improvements in breast
shape, symmetry, and nipple
position.
The procedure is accomplished
by making an incision,
surgically creating a space or
“pocket” under the breast, and
then inserting an appropriately
sized breast implant.
15. a rare complication occurring in
less than 1% of patients in most series.
the first 6 to 12 hours
16. Infection of a breast implant,
following reconstructive or cosmetic
breast surgery, is the most important
complication in the early
postoperative period.
infection after cosmetic
augmentation is a rare occurrence
(1.1%–2.5%), some units report
implant infection rates following
postmastec tomy reconstruction
of up to 35% .
17.
18.
19. Implant Malposition
Careful symmetrical
implant placement is a
critical component of
successful breast
augmentation surgery.
Prior developmental
asymmetry can create
postoperative asymmetry
Developmental asymmetry.
She declined periareolar
mastopexy.
20. the development of precise, symmetrical
pocket dissection.
The footprint of the implant pockets should
be exactly where the surgeon desires the
implants to lie .
Excessive pocket development in any
direction can result in implant displacement
in an unwanted direction.
21. A common error with inexperienced
surgeons is lack of lower pole pocket dissection
resulting in excessively high placement of the
implant.
22. Great care should be taken at the inframammary fold
(IMF) to ensure that this is not overdissected,
allowing descent of the implants along the chest wall
beneath the breast gland.
RT. Double
bubble
deformity
with
lowering of the
right
inframammary
crease.
23. overdissection of
the medial aspect
of the breast can
result in
synmastia with
direct contact
between the
implants resulting
in distortion
or obliteration of
the cleavage
She also had an underlying pectus
excavatum deformity
25. Treatment of this problem is usually operative. Attempts can be made
to use elasticated compression banding of the upper chest, but this is
rarely successful
26. the nipples lay closer to the equator of the implant instead
of at the junction of the middle and lower thirds
Surgical intervention requires reopening of the incision with inferior
capsulotomy to lower the implant to the correct level in relation to
the inframammary crease. If the crease is very tight and well defined,
it may require radial scoring in order to achieve an adequate release to
create enough room for the implant to sit comfortably in its new
position.
27. • Overdissection at the
inframammary crease while
releasing pectoralis major
in dual-plane augmentation.
• Failure to respect and re-create
the IMF during closure after
augmentation.
When closing the inframammary
incision , it is important to tack
Scarpa’s fascia to the chest wall, to
prevent the double bubble
deformity.
especially in very small-breasted
women who have a tightly defined
IMF with short IMF to nipple
distance.
28. “popcorn capsulorrhaphy” refers to the
technique of touching
the implant capsule with electrocautery
causing scattered small burns in
the capsular tissue resulting in shrinkage and
fibrosis of the capsule.
29.
30. one of the most
common complications
of any implant-based
procedure in breast
surgery.
The FDA in the United
States
reported rates of
contracture were
approximately 25% for
breast augmentation and
35% for breast
reconstruction.
Capsular Contracture
31. Capsular contracture
the development of an
acellular collagenous
sheath (scar tissue)
surrounding the implant.
around every foreign
device placed in the
body.
For unclear reasons
becomes reactive and
contracts, resulting in a
tight, distorted
appearance of the
breast.
32. Capsular contracture was classified by Baker in
1975 as follows:
•• Grade I: Soft
•• Grade II: Minimal contracture; implant
palpable but not visible
•• Grade III: Moderate contracture; implant
palpable and visible
•• Grade IV: Severe contracture; hard, painful
breast, with distortion
33. Typically early contracture can be improved with aggressive
displacement exercises.
It is our practice to add a smooth muscle relaxant (Pavabid
150 mg po bid for 3 months; Pavabid is an oral formulation
of Papaverine) to aid in the effect.
For more severe or mature contractures, surgical release of
the scar is required. Most commonly this procedure involves
complete removal of the scar in the form of a capsulectomy
34.
35. An 8 × 8 cm square
sheet of porcine
acellular dermal
matrix sutured
below the lower
pole of
an implant at
capsulectomy and
implant exchange
for contracture
reduction.
36.
37.
38. is a function of
implant type and
soft tissue
coverage.
The thinner the
coverage the
more likely a
patient is to
experience
rippling.
Rippling
the lateral rippling due to lack of breast and
subcutaneous fat for camouflage.
acellular dermal matrix and smooth surface
cohesive gel implants may be of value as
no autologous fat donor sites.
39.
40. the rate of rupture increases
over the life of the implant.
diagnosis is rare on clinical
examination.
This is essential to avoid an
unnecessary delay in diagnosis.
In this patient, the presenting
complaint was nipple discharge
of silicone implant material
which has never before been
documented.
Silicone implant rupture
41. a complete capsulectomy
removal of any free silicone.
If the rupture is extra-capsular,
resection of any visible or
palpable granulomas present in
the breast parenchyma
42.
43. Breast implant-
associated anaplastic
large cell lymphoma
(BIA-ALCL)
a type of peripheral T-
cell non-Hodgkin’s
lymphoma arising
around breast implants.
first described in 1997
.
In 2016, the WHO
designated BIA-ALCL as
a new clinical entity. PET CT shows peri-implant effusion (Eff)
contained by a fibrous capsule (cap) on the
left breast. The implant (Imp) appears
distorted by the effusion.
44. Hypothesis for progression of immune responding T lymphocytes to BIA-ALCL.
is caused by persistent T-cell immune reactions to chronic stimulation from
bacteria and/or toxins implant derived, and subsequent genetic events.
45. The US Food and Drug Administration
(FDA) has reported a total of 573 cases and 33
deaths worldwide as of July 2019
Like other breast diseases, triple
assessment is the golden rule for the
diagnosis of BIA-ALCL.
However, a proportion of cases may progress
to disseminated disease or even death,
highlighting the importance of awareness
and understanding of BIA-ALCL
46. The U.S Food and Drug administration recommends that all women with silicone
gel implants should undergo breast implant imaging 3 years after implant
placement and then every 2 years thereafter
MRI with a dedicated breast implant protocol is the most
sensitive and specific imaging modality
47. A 46-year-old woman
underwent breast
augmentation surgery using a
silicone implant for 6 years.
She noted left breast
enlargement associated with
local pain for 2 months
The ultrasound ___a voluminous
intracapsular collection inside
the left silicone implant capsule,
collection contained suspension
debris.
drained by percutaneous
aspiration, with the
diagnosis of BIA-ALCL on
her left breast at cytology.
breast magnetic resonance
imaging (BMRI)
48. She underwent surgical
explantation ( “en
bloc”capsulectomy) of
bilateral breast implants.
Histopathology
confirmed BIA-ALCL on
her left breast and SIGBIC
on her right breast.
No further treatment was
required.
follow-up by BMRI was
opted
SIGBIC, silicone induced
granuloma of breast implant
capsule
1 week after bilateral “en bloc”
capsulectomy.
49. Due to the influence of online media,
women worldwide share their opinions
regarding their surgical experiences .
Surgeons should closely follow up with
their patients and respect their wishes
by removing the implants when
requested .
a better-informed consent process
should be implemented, especially
for breast augmentation surgery in
order to avoid legal issues
“Breast Implant Illness”.