CLICK HERE TO BETTER UNDERSTAND: https://youtu.be/uBhw0gq2kGc Discipline: Physiology Topic: Body fluid(Part 4) Learning outcome: 6.COMPOSITION OF DIFFERENT FLUID COMPARTMENT 7. PREVIOUS YEAR QUESTIONS

1. 1.Body Fluid
(Part:4)
Dr. Nishu Verma
Discipline: Physiology

2. Learning outcome:Learning outcome:Learning outcome:Learning outcome:
1.BODY COMPOSITION (AS % OF BODY WEIGHT)
2.Body Water as % Body Weight
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3.Measurement of Body Fluid
4.Substances Used for Measurement of Various Compartments
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5. Darrow-Yannet Diagram
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6.COMPOSITION OF DIFFERENT FLUID COMPARTMENT
7. PREVIOUS YEAR QUESTIONS

3. 6.COMPOSITION OF DIFFERENT FLUID COMPARTMENT
1. ECF 2. ICF
Predominant ECF
Sodium content in body
Predominant ICF
Potassium content of body

4.  Quick digest:
• The dissimilarity between the anions in the ICF and the ECF is largely determined by the presence of
intracellular molecules that do not cross the cell membrane.
• Ca++ ion concentration is least in ICF
• The difference in the distribution of cations (sodium and potassium) is a result of the activity of the Na+ – K+
- ATPase pump.
• It is important to note that:
• Only the exchangeable solutes are osmotically active.
• Exchangeable pool.
• Non-exchangeable.

5. PREVIOUS YEAR
QUESTIONS
(AIIMS, JIPMER,PGI etc)

6. 1.Interstitial fluid volume can be calculated by: [AIIMS]
a. Radioactive iothalamate
b. Using radiolabeled water and 133I labeled albumin
c. Using radiolabeled water
d. Radiolabeled Na+ and radiolabeled albumin

7. 2. K+ homeostasis in human is: [PGI ]
a. Most of the K+ are intracellular
b. Most of the K+ extracellular
c. An essential electrolyte for different organ functions
d. Actively secreted in the distal tubules
e. Maintains the Na+-K+ ATPase activity

8. 3. Potassium is maximum in: [PGI]
a. Cell
b. Plasma
c. Interstitium
d. Bone

9. 4. Total body sodium in meq/kg is: [PGI]
a. 42
b. 58
c. 70.7
d. 90.0

10. 5. Plasma K+ constitutes what percentage of total body
potassium? [AIIMS , JIPMER ]
a. 0.4%
b. 7.6%
c. 10.4%
d. 89.6%

11. 6. A man weighing 70 kg, water content of body is: [JIPMER]
a. 20-30L
b. 30-40L
c. 40-45L
d. 50-60L

12. 7. Plasma osmolarity is: [JIPMER]
a. 85-95 mOsm/L
b. 185-195 mOsm/L
c. 285-295 mOsm/L
d. 385-395 mOsm/L

13. 8. The following are true about body water: [PGI]
a. Water constitutes 60% of the body weight
b. Plasma volume constitutes 10% of the total body water
c. ECF volume can be determined by dilution methods
d. 10% is intracellular water

14. 9. ECF forms what percentage of body weight? [AI ]
A.10%
b. 25 %
c. 33%
d. 60%

15. 10. True statements are: [PGI]
a. Total body water constitutes about 60% of body weight
b. Most intracellular water is the musculoskeletal system
c. Extracellular water constitutes about 40% of body weight
d. Total plasma constitutes about 10% body weight
e. Extracellular fluid can be measured by dilution method

16. 11. Which of the following methods is not used for
measurement of body fluid
volumes? [AIIMS]
a. Antipyrine for total body water
b. Inulin for extracellular fluid
c. Evans blue for plasma volume
d. I125 albumin for blood volume

17. 12. Most accurate measurement of extracellular fluid volume
(ECF) can be
done by using: [AIIMS May 03]
a. Sucrose
b. Mannitol
c. Inulin
d. Aminopyrine

18. 13. Predominant extracellular ions are:
a. Na+
b. K+
c. Cl-
d. HCO3
e. PO4

19. 32. True statements about ions composition in body: [PGI]
a. Intracellular and extracellular ions compositions are same
b. Phosphorus and Mg++ are major ions intracellularly
c. Na+ , Cl– principal ions in ECF
d. Kidney tightly regulates Na+ , K+ , Cl composition

20. 14. About sodium, true: [PGI ]
a. Normal serum level is 135-145 mEq/L
b. Daily intake is 150 mmol of NaCl
c. Major portion is extracellular
d. Major reserve is skeletal muscle

21. 15. Total body water differences between male and female is
not seen at the age
of: [JIPMER]
a. Above 60 years
b. 40-60 years
c. 10-18 years
d. 18-25 years

22. Thanks
for
your Attention!!!