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  Biology Futures The revolution in personalized genomics and synthetic biology:  technological status and ethical issues Melanie Swan MS Futures Group +1-650-681-9482 [email_address] www.melanieswan.com June 14, 2008 Slides: http//www.melanieswan.com/presentations/biology_futures.ppt
[object Object],[object Object],[object Object],[object Object],[object Object],Summary June 14, 2008
Agenda ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],June 14, 2008
Key genomics tools June 14, 2008 ,[object Object],[object Object],[object Object],[object Object],[object Object],Sources: http://www.economist.com/background/displaystory.cfm?story_id=7854314,  http://www.molsci.org/%7Ercarlson/Carlson_Pace_and_Prolif.pdf  DNA Synthesizer Variation: SNP
Status of DNA sequencing June 14, 2008 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Ensembl gene browser
Genetic testing revolution ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],June 14, 2008 1 http://www.forbes.com/free_forbes/2007/0618/052_2.html
Direct-to-consumer genomics service 23andme June 14, 2008 580,000 SNPs scanned and mapped to 78 conditions
23andme colorectal cancer marker   June 14, 2008
Direct-to-consumer genomics controversy June 14, 2008 Drawbacks Advantages ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Implications of personalized genomics June 14, 2008 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Synthetic biology revolution ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],June 14, 2008
BioBricks: Registry of Standard Biological Parts ,[object Object],June 14, 2008 Source: http://partsregistry.org (MIT)
BioBricks example: measurement device selection June 14, 2008
BioBricks example: obtain part sequence June 14, 2008
Synthetic biology status ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],June 14, 2008
Biofuels ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],June 14, 2008 Algal Oil
Biofood ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],June 14, 2008 In vitro meat Corn images: http://www:science-interactive.co.uk Wild type corn Enhanced corn
Implications of synthetic biology ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],June 14, 2008 Spore Creature Creator
Bioethics and society ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],June 14, 2008
Ethics of new technology: dual-use debate  June 14, 2008 “ evil” Technophobic (Bill Joy) “ good” Technophilic (Ray Kurzweil) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Biological warfare and public health ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],June 14, 2008
Ethics: practitioner standards  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],June 14, 2008 1 http://biology.plosjournals.org/perlserv/?request=get-document&doi=10.1371/journal.pbio.0060073
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Ethics: intellectual property June 14, 2008
Pedagogy and scientific method ,[object Object],[object Object],[object Object],June 14, 2008 1 http://en.wikipedia.org/wiki/Synthetic_biology ,[object Object],[object Object],[object Object],“ From this combination of passion and inventiveness I sense that students are reinventing literacy. Literacy has been boiled down to reading and writing, but the means have changed since the Renaissance. In a very real sense post-digital literacy now includes 3D machining and microcontroller programming.” – Neil Gershenfeld, MIT 1
Advances in brain research  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],June 14, 2008
Innovations underway ,[object Object],[object Object],[object Object],[object Object],June 14, 2008 Second Health Operating Theatre, Second Life Teraradiology Telemedicine da Vinci Robotic Surgery OR-Live.com
Long-term biology futures ,[object Object],[object Object],[object Object],[object Object],[object Object],June 14, 2008 Image: Natasha Vita-More, Primo Posthuman
[object Object],[object Object],[object Object],[object Object],[object Object],Summary June 14, 2008
Resources ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],June 14, 2008
Thank you Melanie Swan MS Futures Group +1-650-681-9482  [email_address] www.melanieswan.com Slides: http//www.melanieswan.com/presentations/biology_futures.ppt Provided under an open source  Creative Commons 3.0 license

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Biology Futures

  • 1. Biology Futures The revolution in personalized genomics and synthetic biology: technological status and ethical issues Melanie Swan MS Futures Group +1-650-681-9482 [email_address] www.melanieswan.com June 14, 2008 Slides: http//www.melanieswan.com/presentations/biology_futures.ppt
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  • 7. Direct-to-consumer genomics service 23andme June 14, 2008 580,000 SNPs scanned and mapped to 78 conditions
  • 8. 23andme colorectal cancer marker June 14, 2008
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  • 13. BioBricks example: measurement device selection June 14, 2008
  • 14. BioBricks example: obtain part sequence June 14, 2008
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  • 30. Thank you Melanie Swan MS Futures Group +1-650-681-9482 [email_address] www.melanieswan.com Slides: http//www.melanieswan.com/presentations/biology_futures.ppt Provided under an open source Creative Commons 3.0 license