This document discusses bioentrepreneurship, which involves commercializing biotechnology innovations from academia. Bioentrepreneurs take on both business and scientific risks. Examples are given of human drugs developed from biotechnology like insulin and interferons. Plants developed through biotechnology include herbicide-tolerant and pest-resistant crops. While biotechnology development and product consumption varies globally, the US leads in biotech sales and drug development. Bioentrepreneurs rely on founders, friends, family, and federal support. Essential skills include leadership, resilience, learning, and teamwork. Challenges to bioentrepreneurship in Pakistan include a lack of financial support, slow government processes, and disconnect between academia and industry.