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Lincoln, February 2008


     Tackling bioethics in the
classroom – some practical ideas

                              Dr Chris Willmott
                          Dept of Biochemistry
                         University of Leicester
                                 cjrw2@le.ac.uk
                                     University of
                                     Leicester
Ethics in the classroom
Growing importance of (bio)ethics in school curriculum
  • Salters-Nuffield Advanced Biology
  • New AS/A levels from September 2008
  • Perspectives on Science AS level
  • New GCSEs since September 2006
  • Citizenship education
Bioethics = Bio AND Ethics!
     • Science – COULD it be done?
     • Ethics – SHOULD it be done?
Important that both are being considered:
     Science without ethics may be immoral
     Ethics without science may be impossible
Ethics - concerns
e.g. (regarding Ethics dimension of SNAB A level)
“It’s quite a challenging role for a teacher, I think. If
you’ve not got the in depth understanding of a lot of
the ethics which goes behind it… it is quite
unnerving… some of the questions that students can
ask you… it sort of undermines your authority
sometimes”
Anonymous teacher
quoted by Lewis (Jnl Biol Edn 40:101-106, 2006)
Approaches
• Case studies/ scenarios
• Debate and role-play
• Newspapers
• Book extracts
• Guest lectures
• TV programmes
  • Structured activity based on news footage
  • Clips from other programmes
  • Knowing what’s on and when
Approaches
• Case studies/ scenarios




• TV programmes
  • Structured activity based on news footage
  • Clips from other programmes
  • Knowing what’s on and when
Case studies & scenarios
• Case studies allow real-world framing of
  otherwise abstract ideas
• As such, can have a key role in opening up
  complex issues for students
• May be genuine or fictional (though latter work
  best when as close to real as possible)
Case study – Carl and Julie
Carl is a twenty-one year old builder. He is engaged to Julie,
and she has recently discovered that she is expecting their
first child. In 2001, Carl’s maternal grandfather died from
Huntington’s disease (HD), a late-onset degenerative disease
of the nervous system. HD is inherited in a dominant fashion;
if you do have HD, you have a 50% chance of passing it on to
your children. Carl’s mum has decided not to take the test to
find out if she got the faulty copy from her father, but now
that he is expecting to be a father himself, Carl is keen to find
out if there is any risk that he has passed on the condition.
What are some of the issues at stake for Carl and Julie? What
are the consequences of taking the test, or deciding not to?
If you were Carl, what would you do?
Genetic screening
 Carl can know his status and prepare
 accordingly
 But his mum has made a conscious decision
 not to know, hence potential harm to her
 Other consequences:
     - Carl’s relationship with Julie?
     - Carl’s relationship with baby?
     - Implications for Carl’s work?
     - Insurance implications, etc

(Developed from episode of “Bitter Inheritance”)
TV footage – why?
• Familiar visual medium
• Can be used to:
     - convey information
     - as discussion starters
• Clips save time over full programme
What sort of programmes?
• Documentaries, e.g.
     - A child against all odds (2006)
     - Who’s afraid of designer babies? (2005)
     - The dark secret of Hendrik Schön (2004)
• Drama e.g.
     - Holby city (various, esp 2006)
     - The Simpsons (e.g. Trash of the titans, 1998)
     - Million dollar baby (2004)
• News clips
     - topical
     - pithy summary
Example 1: scene setter




South Park: “Kenny Dies”
(Paramount Comedy Channel, 16th Jan 2006)
         This recording is to be used only for educational and non-commercial purposes under the terms of the ERA Licence
Example 2: structured news
                                                                                    Therapeutic Cloning
                    You are going to see a 3 minute video from Five News on June 16th 2004,
                    discussing an application by a team of scientists at Newcastle University for
                    permission to carry out “therapeutic cloning”. Read through these questions
                    before you see the clip, so you know what to look out for.

      From the video
      Explain how therapeutic cloning would work




      What is the source of the eggs to be used in this research?

      What is the stated aim of the research?



      Thinking deeper
      In the clip, Professor Murdoch says:
      “Imagine a child, say a ten year old child, now
      who is diabetic who’s cells that normally produce
      insulin are not working properly, so that child
      will have to take insulin injections for the rest of
      their life. Possibly, in five or ten years time, we
      could be in a situation where we could take a tiny
      piece of skin from that child, do some work within
      the laboratory to tell that skin cell to forget that
      it was ever a skin cell, to learn to become a stem
      cell, which means that it has no background
      information about what it is going to be, and then teach that stem cell to become an insulin secreting
      cell so that cell can be planted back into the child and then the diabetes theoretically would be cured.”

      Compare this with the explanation of how therapeutic cloning would work;
      - in what ways was it different, and


      - in what ways was it the same?


      What objections to stem cell research are mentioned in the video?



      What other reasons (not mentioned) may cause people to object to therapeutic cloning?



      What technical difficulties might make this work difficult to achieve?
Example 2: structured news




Five News Five, June 16th 2004
       This recording is to be used only for educational and non-commercial purposes under the terms of the ERA Licence
Example 3: technical information




A Child Against All Odds BBC1, November 14th 2006
       This recording is to be used only for educational and non-commercial purposes under the terms of the ERA Licence
Example 4: discussion starter




GATTACA Channel 4, September 4th 2005
      This recording is to be used only for educational and non-commercial purposes under the terms of the ERA Licence
GATTACA – questions to consider
GATTACA (Dir: Andrew Niccol, 1997) is set “in the
   not too distant future”. Having watched the clip,
   consider the following questions:
1. How realistic is the genetic screening process
   shown in the film? Which aspects can already be
   done? Which are likely to be more difficult?
2. Screening of this type would be controversial. What
   are some of the potential benefits, and what are
   some of the potential problems?
3. Consider your answers to Q2. What form of ethical
   thinking does each represent?
4. Does this film offer any insights into current
   development in genetic screening?
GATTACA – Science issues
Technology shown could offer selection, not
  enhancement – gene can only be included if mum or
  dad had it!
Current PGD? Future PGD?
Genetic determinism? How much of us as individuals
  is down to our genes and how much down to other
  factors (food intake, trauma, etc)?
GATTACA – Ethical issues
Genetic discrimination – ‘Valids’ v ‘In-valids’? A
  ‘made-man’ v a ‘faith-birth’? A ‘vitro’ v a ‘utero’?
Insurance moratorium in UK (until 2011). Risk and
  social exclusion?
What would it be suitable to check for? Diseases?
  Gender? Physical features? Character traits?
What costs to the individual and to society are worth
  paying in order to select-out diseases?
What do such attitudes say about people with
  disabilities now?
Role of genetics in forensics?
Knowing what’s on and when
For scheduled programmes:
• Radio Times, etc
• www.trilt.ac.uk
Television and Radio Index for Learning and Teaching
Knowing what’s on and when
For scheduled programmes:
• Radio Times, etc
• www.trilt.ac.uk
Television and Radio Index for Learning and Teaching
   • Need to be member of BUFVC to use TRILT
     (cost for Schools = £375 per annum)
• www.tvgenius.co.uk
But, news isn’t known in advance!
• Today programme (Radio 4)
• BBC website, esp. Health and
  Science/Nature sub-sections
Getting hold of programmes & clips
• Off-Air Recordings
      - recorded at time of transmission
      - requires Educational Recording Agency licence
• Back-up www.bufvc.ac.uk/services/offair.html
 British Universities Film & Video Council
• Increasing availability of streamed news clips, esp.
  on the BBC website, but shortly also on the
  Newsfilm online site (http://newsfilm.bufvc.ac.uk)
• Legitimate and unlicensed use of programmes on
  YouTube, Google Video etc
Helpful websites
e.g. www.bioscience.heacademy.ac.uk/resources/ethicsbrief.htm



                                     Bioethics Briefings
                                       Six titles and
                                      others to follow
Helpful websites
e.g. www.beep.ac.uk
Helpful websites
e.g. www.at-bristol.org.uk/cz/Default.htm
Helpful websites: BioethicsBytes
e.g. www.bioethicsbytes.wordpress.com
BioethicsBytes: Drama
BioethicsBytes: Extended Comm.
BioethicsBytes: Streamed News
Acknowledgements
• Bonnie Green and David Willis
• GENIE (the Genetics Education CETL) and the
  National Teaching Fellowship Scheme
• Audio-Visual Services, UoL




                   www.bioethicsbytes.wordpress.com
                     del.icio.us/chriswillmott/bioethics

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Bioethics Classroom

  • 1. Lincoln, February 2008 Tackling bioethics in the classroom – some practical ideas Dr Chris Willmott Dept of Biochemistry University of Leicester cjrw2@le.ac.uk University of Leicester
  • 2. Ethics in the classroom Growing importance of (bio)ethics in school curriculum • Salters-Nuffield Advanced Biology • New AS/A levels from September 2008 • Perspectives on Science AS level • New GCSEs since September 2006 • Citizenship education
  • 3. Bioethics = Bio AND Ethics! • Science – COULD it be done? • Ethics – SHOULD it be done? Important that both are being considered: Science without ethics may be immoral Ethics without science may be impossible
  • 4. Ethics - concerns e.g. (regarding Ethics dimension of SNAB A level) “It’s quite a challenging role for a teacher, I think. If you’ve not got the in depth understanding of a lot of the ethics which goes behind it… it is quite unnerving… some of the questions that students can ask you… it sort of undermines your authority sometimes” Anonymous teacher quoted by Lewis (Jnl Biol Edn 40:101-106, 2006)
  • 5. Approaches • Case studies/ scenarios • Debate and role-play • Newspapers • Book extracts • Guest lectures • TV programmes • Structured activity based on news footage • Clips from other programmes • Knowing what’s on and when
  • 6. Approaches • Case studies/ scenarios • TV programmes • Structured activity based on news footage • Clips from other programmes • Knowing what’s on and when
  • 7. Case studies & scenarios • Case studies allow real-world framing of otherwise abstract ideas • As such, can have a key role in opening up complex issues for students • May be genuine or fictional (though latter work best when as close to real as possible)
  • 8. Case study – Carl and Julie Carl is a twenty-one year old builder. He is engaged to Julie, and she has recently discovered that she is expecting their first child. In 2001, Carl’s maternal grandfather died from Huntington’s disease (HD), a late-onset degenerative disease of the nervous system. HD is inherited in a dominant fashion; if you do have HD, you have a 50% chance of passing it on to your children. Carl’s mum has decided not to take the test to find out if she got the faulty copy from her father, but now that he is expecting to be a father himself, Carl is keen to find out if there is any risk that he has passed on the condition. What are some of the issues at stake for Carl and Julie? What are the consequences of taking the test, or deciding not to? If you were Carl, what would you do?
  • 9. Genetic screening Carl can know his status and prepare accordingly But his mum has made a conscious decision not to know, hence potential harm to her Other consequences: - Carl’s relationship with Julie? - Carl’s relationship with baby? - Implications for Carl’s work? - Insurance implications, etc (Developed from episode of “Bitter Inheritance”)
  • 10. TV footage – why? • Familiar visual medium • Can be used to: - convey information - as discussion starters • Clips save time over full programme
  • 11. What sort of programmes? • Documentaries, e.g. - A child against all odds (2006) - Who’s afraid of designer babies? (2005) - The dark secret of Hendrik Schön (2004) • Drama e.g. - Holby city (various, esp 2006) - The Simpsons (e.g. Trash of the titans, 1998) - Million dollar baby (2004) • News clips - topical - pithy summary
  • 12. Example 1: scene setter South Park: “Kenny Dies” (Paramount Comedy Channel, 16th Jan 2006) This recording is to be used only for educational and non-commercial purposes under the terms of the ERA Licence
  • 13. Example 2: structured news Therapeutic Cloning You are going to see a 3 minute video from Five News on June 16th 2004, discussing an application by a team of scientists at Newcastle University for permission to carry out “therapeutic cloning”. Read through these questions before you see the clip, so you know what to look out for. From the video Explain how therapeutic cloning would work What is the source of the eggs to be used in this research? What is the stated aim of the research? Thinking deeper In the clip, Professor Murdoch says: “Imagine a child, say a ten year old child, now who is diabetic who’s cells that normally produce insulin are not working properly, so that child will have to take insulin injections for the rest of their life. Possibly, in five or ten years time, we could be in a situation where we could take a tiny piece of skin from that child, do some work within the laboratory to tell that skin cell to forget that it was ever a skin cell, to learn to become a stem cell, which means that it has no background information about what it is going to be, and then teach that stem cell to become an insulin secreting cell so that cell can be planted back into the child and then the diabetes theoretically would be cured.” Compare this with the explanation of how therapeutic cloning would work; - in what ways was it different, and - in what ways was it the same? What objections to stem cell research are mentioned in the video? What other reasons (not mentioned) may cause people to object to therapeutic cloning? What technical difficulties might make this work difficult to achieve?
  • 14. Example 2: structured news Five News Five, June 16th 2004 This recording is to be used only for educational and non-commercial purposes under the terms of the ERA Licence
  • 15. Example 3: technical information A Child Against All Odds BBC1, November 14th 2006 This recording is to be used only for educational and non-commercial purposes under the terms of the ERA Licence
  • 16. Example 4: discussion starter GATTACA Channel 4, September 4th 2005 This recording is to be used only for educational and non-commercial purposes under the terms of the ERA Licence
  • 17. GATTACA – questions to consider GATTACA (Dir: Andrew Niccol, 1997) is set “in the not too distant future”. Having watched the clip, consider the following questions: 1. How realistic is the genetic screening process shown in the film? Which aspects can already be done? Which are likely to be more difficult? 2. Screening of this type would be controversial. What are some of the potential benefits, and what are some of the potential problems? 3. Consider your answers to Q2. What form of ethical thinking does each represent? 4. Does this film offer any insights into current development in genetic screening?
  • 18. GATTACA – Science issues Technology shown could offer selection, not enhancement – gene can only be included if mum or dad had it! Current PGD? Future PGD? Genetic determinism? How much of us as individuals is down to our genes and how much down to other factors (food intake, trauma, etc)?
  • 19. GATTACA – Ethical issues Genetic discrimination – ‘Valids’ v ‘In-valids’? A ‘made-man’ v a ‘faith-birth’? A ‘vitro’ v a ‘utero’? Insurance moratorium in UK (until 2011). Risk and social exclusion? What would it be suitable to check for? Diseases? Gender? Physical features? Character traits? What costs to the individual and to society are worth paying in order to select-out diseases? What do such attitudes say about people with disabilities now? Role of genetics in forensics?
  • 20. Knowing what’s on and when For scheduled programmes: • Radio Times, etc • www.trilt.ac.uk Television and Radio Index for Learning and Teaching
  • 21. Knowing what’s on and when For scheduled programmes: • Radio Times, etc • www.trilt.ac.uk Television and Radio Index for Learning and Teaching • Need to be member of BUFVC to use TRILT (cost for Schools = £375 per annum) • www.tvgenius.co.uk But, news isn’t known in advance! • Today programme (Radio 4) • BBC website, esp. Health and Science/Nature sub-sections
  • 22. Getting hold of programmes & clips • Off-Air Recordings - recorded at time of transmission - requires Educational Recording Agency licence • Back-up www.bufvc.ac.uk/services/offair.html British Universities Film & Video Council • Increasing availability of streamed news clips, esp. on the BBC website, but shortly also on the Newsfilm online site (http://newsfilm.bufvc.ac.uk) • Legitimate and unlicensed use of programmes on YouTube, Google Video etc
  • 23. Helpful websites e.g. www.bioscience.heacademy.ac.uk/resources/ethicsbrief.htm Bioethics Briefings Six titles and others to follow
  • 26. Helpful websites: BioethicsBytes e.g. www.bioethicsbytes.wordpress.com
  • 30. Acknowledgements • Bonnie Green and David Willis • GENIE (the Genetics Education CETL) and the National Teaching Fellowship Scheme • Audio-Visual Services, UoL www.bioethicsbytes.wordpress.com del.icio.us/chriswillmott/bioethics