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Digestion
     and
   Absorption
     of
   Proteins




Biochemistry for Medics   1
Digestion of dietary proteins




      Biochemistry for Medics   2
Characteristics of proteolytic enzymes




           Biochemistry for Medics       3
Digestion in the oral cavity




         Biochemistry for Medics   4
Digestion by gastric juice




         Biochemistry for Medics   5
Functions of Proteolytic enzymes
              Pepsin




                                      6
            Biochemistry for Medics
Functions of proteolytic enzymes
                         Rennin




     Biochemistry for Medics       7
Functions of proteolytic enzymes
   Gastriscin and Gelatinase




      Biochemistry for Medics      8
Digestion by gastric juice- Over view




         Biochemistry for Medics        9
Digestion by Pancreatic Juice




                                       10
             Biochemistry for Medics
Role of Trypsin

-Secreted    in the zymogen form (Trypsinogen)and
activation is brought about by Enterokinase (secreted
by the intestinal mucosa ) and by Trypsin itself. Trypsin
is specific for cleaving peptide bonds contributed by
basic amino acids.
Required for activation of Chymotrypsin
 Required for conversion of pro-elastase to elastase
It is required for conversion of fibrinogen to fibrin
It has weak action on casein
               Biochemistry for Medics                      11
Role of Chymotrypsin




         Biochemistry for Medics   12
Role of Carboxy-peptidases




        Biochemistry for Medics   13
Role of Elastase and Collagenase




        Biochemistry for Medics    14
Biochemistry for Medics   15
Digestion by intestinal Juice




         Biochemistry for Medics   16
Functions of the Intestinal enzymes




        Biochemistry for Medics       17
Functions of Intestinal enzyme(Contd.)




         Biochemistry for Medics         18
Diseases associated with digestion
of proteins




        Biochemistry for Medics      19
Steatorrhea




       Biochemistry for Medics   20
Absorption of amino acids




        Biochemistry for Medics   21
Absorption of amino acids




        Biochemistry for Medics   22
Absorption of Oligopeptides




        Biochemistry for Medics   23
Role of glutathione




        Biochemistry for Medics   24
Meister cycle




Biochemistry for Medics   25
Clinical Significance




         Biochemistry for Medics   26
Food Allergies




        Biochemistry for Medics   27
Summary




          Biochemistry for Medics   28

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