This document provides information about various radiological studies of the gastrointestinal tract including barium swallow, barium meal, barium follow through, and barium enema. It describes the anatomy of the esophagus and conditions that can be examined using barium swallow such as achalasia, Barrett's esophagus, and esophageal cancer. Techniques, indications, contraindications and findings for each study are summarized. Common abnormalities that can be identified on these studies including ulcers, polyps, tumors and inflammatory conditions are also outlined.
Learn Barium Meal & Follow Through for the beginners from a Radiology Resident.For some image description please go through the text book "David Sutton" because i have described these image during my presentation Verbally..There are many animations used inside this presentation so to see all the pictures which are placed layer by layer with the help of animations you simple need to download this presentation first.... Thanx.
Full story fatty liver imaging Dr Ahmed EsawyAHMED ESAWY
Full story fatty liver imaging dr ahmed esawy
include different cases for oral radiodiagnosis examination all over the world
CT /MRI Plain X ray images
Diagnosis at US
Diagnosis at CT
Diagnosis at MR Imaging
Elastography
Contrast enhanced ultrasound
Liver Pathology (Diffuse Diseases).
Criteria for fatty liver on USG
Grading of fatty liver
Fatty fibrotic pattern
Diagnosis at CT
Diagnosis at MR Imaging
Potential pitfalls in Opposed-phase T1 include
Accuracy for Detection and Grading of Fat Deposition
Patterns of Fat Deposition
Diffuse Deposition.
Focal Deposition and Focal Sparing.
Multifocal Deposition.
Perivascular Deposition.
Subcapsular Deposition.
Focal Deposition and Focal Sparing
Fatty Pseudolesions of the Liver: Postoperative Changes
Differential Diagnosis
Primary Lesions and Hypervascular Metastases.
Hypovascular Metastases and Lymphoma.
Perfusion Anormalies.
Periportal Abnormalities
Pitfalls
Fat-containing Primary Tumors.
Low-Attenuation Lesions.
Focal Sparing that Mimics an Enhanced Tumor.
Barium meal ppt presentation is very important for radiology resident , radiologist and radiographers. this slide contents lots of barium image and technique, position, indication and modification and lots of information. this presentation help alot thanks .
Learn Barium Meal & Follow Through for the beginners from a Radiology Resident.For some image description please go through the text book "David Sutton" because i have described these image during my presentation Verbally..There are many animations used inside this presentation so to see all the pictures which are placed layer by layer with the help of animations you simple need to download this presentation first.... Thanx.
Full story fatty liver imaging Dr Ahmed EsawyAHMED ESAWY
Full story fatty liver imaging dr ahmed esawy
include different cases for oral radiodiagnosis examination all over the world
CT /MRI Plain X ray images
Diagnosis at US
Diagnosis at CT
Diagnosis at MR Imaging
Elastography
Contrast enhanced ultrasound
Liver Pathology (Diffuse Diseases).
Criteria for fatty liver on USG
Grading of fatty liver
Fatty fibrotic pattern
Diagnosis at CT
Diagnosis at MR Imaging
Potential pitfalls in Opposed-phase T1 include
Accuracy for Detection and Grading of Fat Deposition
Patterns of Fat Deposition
Diffuse Deposition.
Focal Deposition and Focal Sparing.
Multifocal Deposition.
Perivascular Deposition.
Subcapsular Deposition.
Focal Deposition and Focal Sparing
Fatty Pseudolesions of the Liver: Postoperative Changes
Differential Diagnosis
Primary Lesions and Hypervascular Metastases.
Hypovascular Metastases and Lymphoma.
Perfusion Anormalies.
Periportal Abnormalities
Pitfalls
Fat-containing Primary Tumors.
Low-Attenuation Lesions.
Focal Sparing that Mimics an Enhanced Tumor.
Barium meal ppt presentation is very important for radiology resident , radiologist and radiographers. this slide contents lots of barium image and technique, position, indication and modification and lots of information. this presentation help alot thanks .
various congenital gastrointestinal diseases manifesting in childhood or even in adults, their radiographic findings on various imaging modalities such as radiograph, barium, ultrasound etc.
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
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- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
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Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
3. BARIUM SWALLOW:
Barium swallow is a
radiological study of
pharynx and esophagus up
to the level of stomach with
the help of contrast.
4. ANATOMYOFESOPHAGUS:
Flattened muscular tube, size
18 to 26cm beginning at lower
border of cricoid cartilage (opp
6th cervical vertebra) and
ending at cardiac orifice of
stomach (opp 11th thoracic
vertebra)
Divided into 3 anatomical
segments i.e. cervical, thoracic
& abdominal
5. ESOPHAGEAL CONSTRICTION:
• Superiorly: level of Cricoid
cartilage, juncture with
pharynx
• Middle: crossed by aorta and
left main bronchi
•Inferiorly: diaphragmatic
sphincter
6. INTRODUCTION:
• It is a medical imaging procedure used to
examine upper gastrointestinal tract, which
include the esophagus and to a lesser extent
the stomach.
• The contrast used is barium sulfate.
7. CONTRAST:
• TYPES OF CONTRAST STUDY
• (i) SINGLE CONTRAST STUDY
• (ii) DOUBLE CONTRAST STUDY
• Barium Sulfate is used (barium Carbonate is toxic)
• Barium has atomic no 56 and is radio-opaque
• Barium is inert and non-toxic
8. INDICATIONS:
• Dysphagia
• Heart burn, retrosternal pain, regurgitation & odynophagia.
• Hiatus hernia
• Reflux esophagitis
• Stricture formation.
• Esophageal carcinoma.
• Motility disorder like
• Achalasia
• diffuse esophageal spasms.
• Pressure or invasion from extrinsic lesions.
• Assessment of abnormality of
• i. pharyngo esophageal junction including zenkers
diverticulum
• ii.
• iii.
cricoid webs
cricopharyngealAchalasia.
9. CONTRAINDICATIONS:
• Suspected leakage from esophagus into the mediastinum
or pleura and peritoneal cavities (Diatrazole Meglumine -
66% to be used)
• Tracheo-esophageal fistula (Diatrazole Meglumine -66%
to be used)
• Recent Biopsy
11. TECHNIQUE:
• Single Contrast Study:
-Contrast 90-100%W/V
-Approx. 20 ml of contrast given & asked to swallow by
patient.
• Double contrast Study:
-Contrast high density, low viscosity (200-250%W/V)
-15-20 ml given & asked to swallow.
-Then effervescent powder given with another mouthful of
barium.
-In erect posture gas tend to stay up so adequate
distention stays longer time.
-Inj. buscopan I.V given before the procedure to keep
13. ESOPHAGEALWEB:
A shelf like projection is
seen in upper part of
cervical esophagus
causing short segment
narrowing, however
contrast is seen passing
distally.
14. DIFFUSE OESOPHAGEALSPASM
• Barium swallow shows
irregular areas of narrowing
and dilatation -----
“corkscrew” “rosary bead"
esophagus.
The esophageal muscle is
hypertrophied, but histologically
normal.
15. ACHALASIACARDIA
• Barium swallow showing
dilatation of the esophageal
body
•
A “bird-peak " like tapering of
the esophagus at the lower
esophageal end.
16. HIATUSHERNIA:
• Displacement of the cardio-
esophageal junction above
the esophageal hiatus
•
Part of the stomach is
present in the chest
•
Reflux of barium into the
esophagus
19. ZENKER’SDIVERTICULUM:
A Zenker's diverticulum is a pulsion
hypo pharyngeal false diverticulum
with only mucosa and sub mucosa
protruding through triangular posterior
wall weak site (Killian's dehiscence)
between horizontal and oblique
components of cricopharyngeus
muscle.
The esophagogram shows contrast
filled out pouching from posterior wall
of esophagus at the level of
cricopharyngeus.
20. CANDIDA ESOPHAGITIS
Shaggy esophagus associated
with Candida infection , image
"A" depicts the longitudinally
oriented plaque-like lesions
visible in Candida esophagitis ,
image "B" depicts the granular
appearance of the esophageal
mucosa secondary to edema
and inflammation
21. CA ESOPHAGUS
• Irregular long segment
narrowing with proximal and
distal end shouldering and
dilatation with hold up of
contrast in proximal
esophagus
• However contrast is showing
passing distally
23. BARIUM MEAL:
• Barium meal is radiological study of lower esophagus,
stomach and duodenum.
• Done by oral administration of contrast media barium
sulphate.
24. INDICATIONS:
• 1.Dyspepsia
• 2.Weight loss
• 3.Upper abdominal mass
• 4.Gastrointestinal hemorrhage or unexplained iron
deficiency anemia
• 5. Partial obstruction
26. CONTRAST:
• 150 ml of high density barium 250 % W/V (Double
contrast) and 80-100% W/V (single contrast)
METHODS :
• 1. Double contrast: Method of choice to demonstrate
mucosal pattern.
• 2. Single Contrast:
• a) Children -since it usually is not necessary to
demonstrate mucosal pattern
• b) Very ill adults – to demonstrate gross pathology only
27. PROCEDURE
Patient swallows effervescent agent (only in double
contrast)
• High density barium(250% w/v) is swallowed while
lying on the left side. Then turn to the supine position.
If reflux is observed spot films are taken
⋅
A hypotonic agent –Buscopan(20 mg I.V ) is
administered
⋅
Patient rolled from side to side so barium coats
mucosal surfaces by washing mucus from the gastric
mucosa
33. GASTRICPOLYP
• Multiple well defined filling
defects with a surrounding
ring of barium are noted
along the dependent wall
of stomach suggesting
multiple gastric polyps
34. GASTRICDIVERTICULUM
• An out pouching is noted
from the greater curvature of
stomach showing air contrast
level in it suggestive of
gastric diverticulum
35. PYLORICSTENOSIS
• Grossly dilated stomach with
a streak of contrast passing
through narrow elongated
pylorus suggestive of pyloric
stenosis
36. BENIGNTUMOR
• A well defined lesion seen
projecting from fundus of
stomach making obtuse
angle with the wall and
surrounding normal mucosa
suggestive of benign GIST.
37. GASTRIC CARCINOMA
• Marked mucosal
irregularity is noted
involving lower end of
lesser curvature and
gastric antrum causing
marked luminal
narrowing with only
streak of contrast
passing distally
suggestive of neoplastic
etiology.
39. • Barium Follow Through is designed to
demonstrate the small bowel from the
duodenum to the ileoceacal region
encompassing the duodenum , jejunum and
ileum including the junctions superiorly
with the stomach and inferiorly with the
ascending colon.
• Also known as barium meal follow through
(BMFT) & small bowel follow through (SBFT).
41. METHODS:
• Single Contrast
• Double Contrast (with addition of an effervescent agent)
• Note: Double contrast technique is normally adopted
CONTRAST MEDIUM:
• Single Contrast 300-400 ml of 50-60% w/v Barium
suspension
• Double Contrast 300-400 ml of 80-100% w/v Barium
suspension
42. PROCEDURE:
• Barium sulphate solution 80-100% w/v 300 ml (150
ml if performed immediately after barium meal)
• Usually given in 10-15 min increments or full at once
• In situations where barium is contraindicated, non-ionic
water soluble solutions are used.
43. FILMING:
• Prone PAfilms of the abdomen are taken.
• The first radiograph is taken 10 min following the drink,
with the second image at 30 min stage. Then the
radiographs are taken at 30 min intervals until the barium
has reached terminal ileum.
• Pressure on the abdomen helps to compress abdominal
contents so that the loops of small bowel are separated.
Thus for better radiographic quality, prone position is
used.
• Spot films of the terminal ileum are taken supine.
49. ADVANTAGES:
• Easily performed.
• No discomfort/intubation to the patient.
• It is a physiological process. Hence transit time can be
assessed.
DISADVANTAGES :
• Overlapping of Barium filled bowel loops in the pelvis.
• Poor distension of bowel loops
57. BARIUMENEMA:
• A barium enema is a test used to help visualize the colon
(large bowel).
• A barium enema is used to look for problems in the colon,
such as polyps, inflammation (colitis), narrowing of the
colon, tumors, diverticulitis.
60. CONTRAST:
• 500 ml barium suspension used
• 1. SINGLE CONTRAST STUDY (20% W/V)
The colon is filled with barium, which outlines the intestine and
reveals large abnormalities.
• 2. DOUBLE CONTRAST (100% W/V)
• the colon is first filled with barium
• then the barium is drained out, leaving only a thin layer of
barium on the wall of the colon.
• The colon is then filled with air. This provides a detailed view of
the inner surface of the colon, making it easier to see narrowed
areas (strictures), diverticula, or inflammation.