The document provides an overview of the axial skeleton, which includes the skull, vertebral column, and thoracic cage. Key points include:
- The skull is made up of cranial and facial bones that form the cranium and face, protecting the brain and organs. Sutures connect the bones.
- The vertebral column consists of 26 bones including 24 vertebrae that provide support, protect the spinal cord, and allow movement.
- The thoracic cage is made up of ribs and sternum, forming a protective structure around vital chest organs.
Anatomy of skeleton system full/Human all BonesMdMehbubAlam
All about human skeleton system
Full Skeleton system
Appendicular Skeleton
Axial Skeleton
Rib cage
Skull bones
Facial bones
Ear bones
Humerus bone
Femur bone
Tarsals
Carpals
Falanges
The topic includes:
definition and function bone
classification of bone according to shape, development, region and structure
gross structure of long bone
parts of a bone (epiphysis, diaphysis, metaphysis and epiphysial plate of cartilage)
blood supply of bone
growth of a long bone
The skeletal system provides support and protection for the body’s internal organs and gives the muscles a point of attachment. Humans have an endoskeleton, where our bones lie underneath our skin and muscles. In other animals, such as insects, there is an exoskeleton on the outside of the body.
Anatomy of skeleton system full/Human all BonesMdMehbubAlam
All about human skeleton system
Full Skeleton system
Appendicular Skeleton
Axial Skeleton
Rib cage
Skull bones
Facial bones
Ear bones
Humerus bone
Femur bone
Tarsals
Carpals
Falanges
The topic includes:
definition and function bone
classification of bone according to shape, development, region and structure
gross structure of long bone
parts of a bone (epiphysis, diaphysis, metaphysis and epiphysial plate of cartilage)
blood supply of bone
growth of a long bone
The skeletal system provides support and protection for the body’s internal organs and gives the muscles a point of attachment. Humans have an endoskeleton, where our bones lie underneath our skin and muscles. In other animals, such as insects, there is an exoskeleton on the outside of the body.
The skeletal system includes all of the bones and joints in the body. Each bone is a complex living organ that is made up of many cells, protein fibers, and minerals. The skeleton acts as a scaffold by providing support and protection for the soft tissues that make up the rest of the body. The skeletal system also provides attachment points for muscles to allow movements at the joints. New blood cells are produced by the red bone marrow inside of our bones.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
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2. Skeletal System
• The bones of the skeleton form an internal framework to
support soft tissues, protect vital organs, bear the body’s
weight, and help us move.
• Typically, there are 206 bones in an adult skeleton,
although this number varies in some individuals.
• A larger number of bones are present at birth, but the
total number decreases with growth and maturity as
some separate bones fuse.
7-2
3. Skeletal System
– The axial skeleton is composed of the bones
along the central axis of the body,
• the skull
• the vertebral column
• the thoracic cage
– The appendicular skeleton consists of the
bones of the appendages
• upper and lower limbs
• the bones that hold the limbs to the trunk of the
body.
7-3
6. The Skull
– Cranial bones form the rounded cranium,
which completely surrounds and encloses the
brain.
– Facial bones form the bones of the face. They
also
• protect the entrances to the digestive and
respiratory systems as well as
• provide attachment sites for facial muscles
7-6
7. The Mandible
• The lower jaw is formed by the mandible.
• The prominent “chin” of the mandible is
called the mental protuberance.
7-7
8. Cavities of The Skull
– The largest cavity is the cranial cavity, which
encloses, cushions, and supports the brain.
– The skull also has several smaller cavities,
including the orbits (eye sockets), the oral
cavity (mouth), the nasal cavity, and the
paranasal sinuses.
7-8
11. Markings of the Skull
• Numerous bone markings
– canals
– fissures
– foramina
• passageways for blood vessels and nerves
7-11
12. Sutures of the Skull
• Sutures are immovable fibrous joints that form
the boundaries between the cranial bones.
• Dense regular connective tissue seals cranial
bones firmly together at a suture.
• Allow the cranium to grow and expand during
childhood.
• In adulthood, when cranial growth has stopped,
the sutures fuse and are obliterated.
7-12
31. Sinuses
• Have a mucous lining that helps to
humidify and warm inhaled air.
• Cause these skull bones to be lighter.
• Provide resonance to the voice.
7-31
36. Auditory Ossicles
• Three tiny ear bones called auditory
ossicles are housed within the petrous
region of each temporal bone.
• the malleus
• the incus
• the stapes
7-36
37. Hyoid Bone
– Slender, curved bone located inferior to the
skull between the mandible and the larynx
(voice box).
– Does not articulate with any other bone in the
skeleton.
– Serves as sites for attachment for tongue and
larynx muscles and ligaments.
7-37
40. Fontanels
• The regions between the cranial bones are thickened,
fibrous membrane remnants that are not yet ossified.
• Sometimes referred to as the “soft spots” on a baby’s
head.
• They close by 15 months of age.
• When a baby travels through the birth canal, the cranial
bones overlap at these fontanels, in order to ease the
baby’s passage.
• Newborns frequently have a “cone-shaped” head due to
this temporary deformation.
7-40
42. The Vertebral Column
•
Composed of 26 bones, including
– 24 individual vertebrae and the
– fused vertebrae that form both the sacrum and the coccyx
•
The vertebral column has several functions:
– providing vertical support for the body
– supporting the weight of the head
– helping to maintain upright body position
– helping to transfer axial skeletal weight to the appendicular
skeleton of the lower limbs
– housing and protecting the delicate spinal cord and providing a
passageway for spinal nerves connecting to the spinal cord
7-42
46. Three Main Spinal Curvature
Deformities
– Kyphosis is an exaggerated thoracic curvature that is directed
posteriorly, producing a “hunchback” look.
– Lordosis is an exaggerated lumbar curvature, often called
“swayback,” that is observed as a protrusion of the abdomen
and buttocks.
– Scoliosis is an abnormal lateral curvature that sometimes results
during development when both the vertebral arch and body fail
to form, or form incompletely, on one side of a vertebra.
• scoliosis is the most common spinal curvature deformity.
7-46
52. Thoracic Cage
• Consists of the thoracic vertebrae posteriorly,
the ribs laterally, and the sternum anteriorly.
• Acts as a protective cage around vital organs,
such as the heart, lungs, trachea, and
esophagus.
• Provides attachment points for many muscles
supporting the pectoral girdles, the chest, the
neck, the shoulders, the back, and the muscles
involved in respiration.
7-52
54. Ribs
• Both males and females 12 pairs
– Ribs 1–7 are called true ribs. At the anterior body wall, the true
ribs connect individually to the sternum by separate cartilaginous
extensions called costal cartilages.
– Ribs 8–12 are called false ribs because their costal cartilages do
not attach directly to the sternum. The costal cartilages of ribs 8–
10 fuse to the costal cartilage of rib 7 and thus indirectly
articulate with the sternum.
– The last two pairs of false ribs (ribs 11 and 12) are called floating
ribs because they have no connection with the sternum.
7-54