The World Antimicrobial Awareness Week (WAAW) was introduced by the World Health Organization (WHO) to increase global awareness of antimicrobial resistance.
The WAAW takes place every year from 18-24th of November.
The theme of World Antimicrobial Awareness Week (WAAW) 2021 is ‘Spread Awareness, Stop Resistance’.
During this week best practices are shared among the general public, health workers and policy makers to show the importance of stopping the further emergence and spread of antibiotic resistance.
Antibiotic resistance,introduction, cause, mechanism and solution of Antibiot...Dr. Sharad Chand
A illustrative representation of the antibiotic resistance, its introduction, cause, mechanism, examples and possible solutions of the antibiotic resistance. with pictorial illustrations for better understanding.
Antibiotic resistance,introduction, cause, mechanism and solution of Antibiot...Dr. Sharad Chand
A illustrative representation of the antibiotic resistance, its introduction, cause, mechanism, examples and possible solutions of the antibiotic resistance. with pictorial illustrations for better understanding.
Dr.sherin elsherbiny
Senior registrar clinical microbiology
AMR coordinator
Infection control auditor
Riyadh region
Meeqat General Hospital ,Madina,KSA
Antibiotics are most common therapeutic agents used in hospitals across world, however, microbial world is becoming resistant day by day, posing special challenges to clinicians specially working in ICU set ups. There are multiple ways to curb this menace, if approached together in antibiotic stewardship way, can bring about wonders and retain therapeutic potentials of these drugs.
Dr.sherin elsherbiny
Senior registrar clinical microbiology
AMR coordinator
Infection control auditor
Riyadh region
Meeqat General Hospital ,Madina,KSA
Antibiotics are most common therapeutic agents used in hospitals across world, however, microbial world is becoming resistant day by day, posing special challenges to clinicians specially working in ICU set ups. There are multiple ways to curb this menace, if approached together in antibiotic stewardship way, can bring about wonders and retain therapeutic potentials of these drugs.
a research presentation done by Augustine Mwaawaaru Level 400) and Matthew Frimpong Antwi (Level 300) students of( Presbyterian University College-Ghana on Antimicrobial resistance and the way foeward in Ghana. contact 0261825262
project selection
Non-numeric models
Sacred cow
Operating necessity
competitive necessity
Competitive Benefit model
non numeric models
Payback period
Net present value
scoring
Principles of the project management
Project and development life cycles
Project phase
Phase gate
Project management processes
Project management process groups
Project management knowledge areas
Why Project Management Matters?
What Is a Project?
What A Project Is Not?
Difference b/w a project and a process
Factors leading to creation of project
Hazards of Project Management
Constraints of Project Management
Importance of Project Management
The Project & Project Manager Competency Model
Awareness session on breast cancer awareness on 21st oct 2021 at Mehran university, Jamshoro organized by American institute of Chemical engineering society AIChE MUET chapter
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...Oleg Kshivets
Overall life span (LS) was 1671.7±1721.6 days and cumulative 5YS reached 62.4%, 10 years – 50.4%, 20 years – 44.6%. 94 LCP lived more than 5 years without cancer (LS=2958.6±1723.6 days), 22 – more than 10 years (LS=5571±1841.8 days). 67 LCP died because of LC (LS=471.9±344 days). AT significantly improved 5YS (68% vs. 53.7%) (P=0.028 by log-rank test). Cox modeling displayed that 5YS of LCP significantly depended on: N0-N12, T3-4, blood cell circuit, cell ratio factors (ratio between cancer cells-CC and blood cells subpopulations), LC cell dynamics, recalcification time, heparin tolerance, prothrombin index, protein, AT, procedure type (P=0.000-0.031). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and N0-12 (rank=1), thrombocytes/CC (rank=2), segmented neutrophils/CC (3), eosinophils/CC (4), erythrocytes/CC (5), healthy cells/CC (6), lymphocytes/CC (7), stick neutrophils/CC (8), leucocytes/CC (9), monocytes/CC (10). Correct prediction of 5YS was 100% by neural networks computing (error=0.000; area under ROC curve=1.0).
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Integrating Ayurveda into Parkinson’s Management: A Holistic ApproachAyurveda ForAll
Explore the benefits of combining Ayurveda with conventional Parkinson's treatments. Learn how a holistic approach can manage symptoms, enhance well-being, and balance body energies. Discover the steps to safely integrate Ayurvedic practices into your Parkinson’s care plan, including expert guidance on diet, herbal remedies, and lifestyle modifications.
Here is the updated list of Top Best Ayurvedic medicine for Gas and Indigestion and those are Gas-O-Go Syp for Dyspepsia | Lavizyme Syrup for Acidity | Yumzyme Hepatoprotective Capsules etc
Basavarajeeyam is an important text for ayurvedic physician belonging to andhra pradehs. It is a popular compendium in various parts of our country as well as in andhra pradesh. The content of the text was presented in sanskrit and telugu language (Bilingual). One of the most famous book in ayurvedic pharmaceutics and therapeutics. This book contains 25 chapters called as prakaranas. Many rasaoushadis were explained, pioneer of dhatu druti, nadi pareeksha, mutra pareeksha etc. Belongs to the period of 15-16 century. New diseases like upadamsha, phiranga rogas are explained.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Awareness Session On Antimicrobial resistance “Antimicrobials: Spread Awareness, Stop Resistance”
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D r. N i m r a z a m a n
P h a r m - D , R P h , M P H , M . P H I L
Awareness Session On Antimicrobial
Awareness
“Antimicrobials: Spread
Awareness, Stop
Resistance”
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Warning !
A n e w p l a g u e i s s w e e p i n g a c r o s s t h e p l a n e t
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Resistance: A global public health issue
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World Antimicrobial Awareness
Week (18-24 Nov)
• The Wor ld Antimicr obial Awar enes s Week (WAAW )
w as introduced b y the World H ealth Or ganization
(W HO) to in c re as e the g lo b a l aw areness o n
antimic r obial r e s is ta n c e .
• The WAAW tak es plac e ever y year from 1 8-2 4th o f
N ovember.
• The theme o f Wor ld Antimicr obial Awar enes s Week
(WAAW ) 2 0 2 1 is ‘S pr ead Aw arenes s, Stop
R es is tanc e’ .
• D ur ing this w eek bes t pr ac tices are shar ed among the
gener al public , health w or kers and polic y mak ers to
s how the impor tance o f s topping the fur ther
emer genc e a n d s pr ead o f antibiotic r es is tanc e .
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As WHO ramps up its fight against antibiotic resistance, a new multi-country survey shows people
are confused about this major threat to public health and do not understand how to prevent it
from growing.
This survey points out some of the practices, gaps in understanding and misconceptions which
contribute to the phenomenon resistance
AND THE RESULTS WERE VERY ALARMING !!!!!
• Almost two thirds (64%) of some 10 000 people who were surveyed across 12 countries say they
know antibiotic resistance is an issue that could affect them and their families, but how it affects
them and what they can do to address it are not well understood.
• 64% of respondents believe antibiotics can be used to treat colds and flu, despite the fact that
antibiotics have no impact on viruses.
• Close to one third (32%) of people surveyed believe they should stop taking antibiotics when they
feel better, rather than completing the prescribed course of treatment.
What is antimicrobial resistance?
Is the community aware about this massive public
health issue
what are their misconceptions and beliefs ?
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What is antimicrobial resistance (AMR)?
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• Antimicrobial resistance (AMR) occurs when bacteria, parasites, viruses or
fungi change to protect themselves from the effects of antimicrobial drugs
designed to destroy them.
• This means previously effective antimicrobial medicines (e.g. antibiotics)
used to treat or prevent infections may no longer work.
• The World Health Organization (WHO) has identified AMR as ‘one of the top
10 global public health threats facing humanity.
• Antimicrobial resistance (AMR) is a global health and development threat. It
requires urgent multisectoral action in order to achieve the Sustainable
Development Goals (SDGs).
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In addition to the impact on a patient’s health, AMR results
in substantial financial cost for patients and healthcare
systems.
Antimicrobial resistance could increase global healthcare
costs by more than 1 trillion $ per year by 2050 .
(https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6929930/)
Each year, 700,000 people die of AMR. Without
action, the death toll could rise even higher, to as
many as 10 million deaths annually by 2050
It cause a 3.8 percent reduction in annual gross
domestic product (GDP), as identified in a 2017
report entitled 'Drug-Resistant Infections: A
Threat to Our Economic Future'.
(https://www.worldbank.org/en/topic/health/brief/antimicrobial-resistance-amr)
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How has antimicrobial resistance
developed?
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What accelerates the emergence and spread of
antimicrobial resistance?
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• AMR occurs naturally over time, usually through genetic
changes.
• Antimicrobial resistant organisms are found in people, animals,
food, plants and the environment (in water, soil and air).
• They can spread from person to person or between people and
animals, including from food of animal origin.
• The main drivers of antimicrobial resistance includes :
the misuse and overuse of antimicrobials;
lack of access to clean water, sanitation and hygiene (WASH)
for both humans and animals; poor infection and disease
prevention and control in health-care facilities and farms;
poor access to quality, affordable medicines, vaccines and
diagnostics;
lack of awareness and knowledge; and lack of enforcement of
legislation.
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ANTIMICROBIAL RESISTANCE AND COVID-19
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• As we find ourselves in a middle of a pandemic, it
becomes even more urgent to highlight antimicrobial
resistance.
• WHO advises that misuse of antibiotics during COVID-19
pandemic could lead to further accelerated emergence
and spread of antimicrobial resistance. COVID-19 is caused
by a virus, not by a bacteria and therefore antibiotics
should not be used to prevent or treat viral infections,
unless bacterial infections are also present.
Key message
Antibiotics do not prevent or
treat COVID-19 but can cause
adverse effects, allergic
reactions, drug interactions and
increase risk of future resistant
infections
COVID-19 pandemic has
presented many additional
challenges (including
antimicrobial shortages)
for managing patients with
infections
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Antimicrobials are unique medicines
In general, the
impact of
medications are
limited to the
patient taking them
Use of antibiotics
has an impact not
just for the patient
using them but the
global community
as well
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Antimicrobial Stewardship
Antimicrobial
stewardship
Right
antimicrobials
Right patient
Right time
Right dose
Right route
Right duration
Right
documentation
Antimicrobial stewardship is
a coordinated program that promotes
the appropriate use of
antimicrobials (including antibiotics),
improves patient outcomes, reduces
microbial resistance, and decreases the
spread of infections caused by
multidrug-resistant organisms.
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• In the community
• General Practice
• Not prescribing antibiotics for colds and
flu
• Delayed prescribing
• Shared decision making
• Public declarations in the practice about
conserving antibiotics
• Pharmacies
• Offering symptomatic support for cold
and flu
Antimicrobial Stewardship – not just
for hospitals
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• In the home
• Not taking antibiotics that haven’t
been prescribed for you
• Discarding old antibiotic medicines
appropriately
• In industry
• Investing in research and development
for antimicrobials
Antimicrobial Stewardship – not just for
hospitals
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To prevent and control the spread of antibiotic
resistance, individuals can:
• Only use antibiotics when prescribed by a
certified health professional.
• Never demand antibiotics if your health
worker says you don’t need them.
• Always follow your health worker’s advice
when using antibiotics.
• Never share or use leftover antibiotics.
• Prevent infections by regularly by washing
hands, preparing food hygienically, avoiding
close contact with sick people, practising
safer sex, and keeping vaccinations up to
date.
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Caption04 appears here
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There are many things each one
of us can do to help limit
antimicrobial resistance
development and spread of
antimicrobial resistant bacteria.
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Are we heading towards
“Post-antibiotic Era”
• Modern medicine, especially surgery and cancer
treatments, depends on effective antibiotics to
minimise the risk of infection
• Currently, antibiotics reduce post-operative infection rates to
below 2%
• 440,000 new cases of drug-resistant tuberculosis annually
• Without effective antibiotics, this could increase to around
40% to 50%. Up to 30% of these patients could die from
resistant bacterial infections
• The risk of mortality without access to effective antibiotics
may make some treatments and surgical procedures too risky
to continue
• 2 million people acquire serious infections due to
antibiotic-resistant bacteria each year and according to
the Centers for Disease Control and Prevention (CDC),
23,000 of them die as a result
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ANTIBIOTIC RESISTANCE CRISIS
An increase in resistant organisms
+
A limited number of new antimicrobial drugs
=
a problematic scenario
The pharmaceutical industry has largely turned away from antibiotic research due to
the low likelihood of getting a return on investment. Any new class of antibiotics
would need to be used sparingly to conserve their effectiveness, meaning sales
would be slow.”
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?
End of the road?
“Antibiotic resistance should be
added to the list of national
emergencies”.
In the nearest future
• Strep throat to a scraped knee could kill you.
• A simple hip replacement would result in 1 and 6 deaths.
• The cost to treat drug-resistant cases is estimated to be at least
double.
Bad bugs need new drugs !
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Superbugs* are visible manifestations of our
prolonged failure to preserve antibiotics
Known but neglected.
Need immediate action
Known but
inevitable
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We need to preserve this resource by working together
Combating antimicrobial resistance: No action today, no cure
tomorrow
Antibiotics
are
a precious
resource
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“
“We must remember that one determined
person can make a significant difference,
and that a small group of determined
people can change the course of history.”
- -Sonia Johnson
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Editor's Notes
The National WAAW 2021 campaign will encourage stakeholders, including policymakers, health care providers, and the general public to recognize that everyone can be an Antimicrobial Resistance (AMR) Awareness champion. Participants are encouraged to spread awareness about what AMR is, share stories about its consequences, and demonstrate how the actions of individuals, families, professionals, and communities affect the spread of AMR.
Antibiotic resistance happens when bacteria change and become resistant to the antibiotics used to treat the infections they cause.
Over-use and misuse of antibiotics increase the development of resistant bacteria
It is reported that bacteria resistant to current antibiotics cause more than 750,000 deaths worldwide every year, this includes 230,000 deaths from multidrug-resistant tuberculosis. Without any action to stop the spread of resistance, it is predicted that this number will rise to 10 million deaths per year by 2050. The economic burden from increasing resistance is estimated to cost about $100 trillion globally by 2050.
Antimicrobial resistance occurs when bacteria develop resistance to an antimicrobial that was previously an effective treatment. Bacteria develop natural defences against antibiotics. When this occurs, potentially due to prolonged exposure to or overuse of a particular antibiotic, the antibiotic’s effectiveness to treat the infection decreases, and may reach a point where the antibiotic has no benefit.
The overuse of antibiotics in health (human and animal) and agriculture has increased the amount of exposure bacteria have to them, giving bacteria more opportunity to develop resistance. The process of natural selection (‘survival of the fittest’ – favouring bacteria that develop the strongest natural defences) fuels the increasing prevalence of antimicrobial resistance.
New challenges in infection control resulting from more complex health care (for example, outpatient chemotherapy) and increasing domestic and international travel have increased the spread of resistant bacteria both between individuals and between countries.
When patients have longer hospital stays, this may increase the chance of patients acquiring resistant organisms from other patients.
AMS is a set of co-ordinated initiatives or activities that together prevent poor prescribing and emergence of resistance. The four pillars of AMS are good governance, restricting antimicrobials to appropriate indications and first line therapies. Auditing, surveillance and using these to undertake quality improvement initiatives. Training and educating the workforce using international, government or in-house educational resources, and providing regular workshops and seminars on using antimicrobials wisely
Delayed prescribing – if a patient is insistent on receiving antibiotics, offering a script but suggesting that it should not be dispensed unless symptoms worsen or fail to improve after a specified time
Shared decision making – providing information to patients about each management option and arriving at a shared decision that incorporates the patient values and preferences
Public declarations in the practice about conserving antibiotics – for example, having signs in the waiting room
https://behaviouraleconomics.pmc.gov.au/projects/nudge-vs-superbugs-behavioural-economics-trial-reduce-overprescribing-antibiotics
Great initiatives in the UK
https://www.patients-association.org.uk/Handlers/Download.ashx?IDMF=a560fc34-925a-447c-ae1f-cd8e9a2639b0&utm_source=The%20King%27s%20Fund%20newsletters%20%28main%20account%29&utm_medium=email&utm_campaign=11717376_NEWSL_HMP%202020-08-04&dm_i=21A8,6Z56O,2H0RHD,S3EY2,1
Delayed prescribing – if a patient is insistent on receiving antibiotics, offering a script but suggesting that it should not be dispensed unless symptoms worsen or fail to improve after a specified time
Shared decision making – providing information to patients about each management option and arriving at a shared decision that incorporates the patient values and preferences
Public declarations in the practice about conserving antibiotics – for example, having signs in the waiting room
https://behaviouraleconomics.pmc.gov.au/projects/nudge-vs-superbugs-behavioural-economics-trial-reduce-overprescribing-antibiotics
Great initiatives in the UK
https://www.patients-association.org.uk/Handlers/Download.ashx?IDMF=a560fc34-925a-447c-ae1f-cd8e9a2639b0&utm_source=The%20King%27s%20Fund%20newsletters%20%28main%20account%29&utm_medium=email&utm_campaign=11717376_NEWSL_HMP%202020-08-04&dm_i=21A8,6Z56O,2H0RHD,S3EY2,1
At this pace, untreatable infections could emerge on a large scale and the world may experience in some cases dramatic situations of the pre-antibiotic era
Since the discovery of penicillin in 1928 and its commercial use in 1940s, many new antibiotics were introduced between 1940 and 1970, the golden era of antibiotic discovery. During the late 1980s and early 1990s, two major groups of antibiotics became very commonly used, the cephalosporins and the fluoroquinolones. Oxazolidinone is the last new antibiotic group introduced with the turn of the century. As is evident from the roadway, discovery of new agents has markedly slowed down in the last 2-3 decades. This has been coupled with emergence of multiple drug resistance in many bacteria, mainly those common in infections in high-dependency hospital practice.