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Uploaded byDr Resu Neha Reddy
Angiotensin, kinins, leukotrienes, prostaglandins & cytokines
This document discusses several biochemical mediators involved in inflammation including renin, angiotensins, kinins, prostaglandins, leukotrienes, cytokines, and platelet-activating factor (PAF). It describes where these mediators are synthesized, their receptors, actions on various organ systems, and physiological roles. Key points include that kinins are potent vasodilators, prostaglandins can cause fever by acting on the hypothalamus, leukotrienes recruit immune cells and cause bronchoconstriction, and cytokines coordinate the immune response and cellular functions.
