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JoyA.Shepard,PhD,RN-BC,CNE
JoyceBuck,PhD(c),MSN,RN-BC,CNE
1
Alterations in Genitourinary Function
(Urinary Tract, Renal, and Reproductive
Conditions)
2
Learning Outcomes
1. Describeanatomy&physiologyof thegenitourinarysystemandpediatric
differences
2. Discussnursingmanagementofchildwithgenitourinarystructuraldefect
3. Developnursingcareplanforchildwithurinarytractinfection
4. Outlineaplantomeetfluidanddietaryrestrictionsofchildwithrenaldisorder
5. Summarizepsychosocialissuesforchildrequiringgenitourinarysurgery
6. Plannursingcareforchildwithacute&chronicrenalfailure
7. Identifygrowth&developmentissuesforchildwithchronicrenalfailure
22
33
3
Comprised of:
Kidneys
Ureters
Bladder
Urethra
Review: Anatomy Urinary System
44
4
A nephron holds:
The Glomerulus
Bowman’s capsule
Proximal tubule
Loop of Henle
Distal tubule
Collecting duct
The Functional Unit of the Kidneys is the Nephron
5
Review: Anatomy of the Kidney
 Outercortex
 Composedoftheglomeruliandconvoluted tubules
ofthenephronandbloodvessels
 Innermedulla
 Composedoftherenalpyramid
5
Review: Function of the Kidney
 Regulates total body water
 Regulates blood pressure (renin-angiotensin-aldosterone)
 Regulates acid-base status
 Regulates electrolytes, calcium and phosphorus
 Converts Vitamin D to the active hormone
(calcitriol)
 Produces Erythropoietin (EPO)
 Removes nitrogenous wastes
 Drug metabolism and removal
6
7
Review: Anatomy Reproductive System
 Pelvic Cavity: contains urinary bladder, and
reproductive organs
 Malereproductive system
 Testes,scrotum,penis,prostate,vasdeferens(drainsintourethra)
Testesproducetestosterone(primarymalesexhormone);spermafter
puberty
 Femalereproductive system
 Ovaries,fallopiantubes,uterus,vagina
Ovariesproduceestrogen(primaryfemalesexhormone);ovumafterpuberty
7
8
Review: Physiology Genitourinary System
 Renal/ Urinary System
 Main function – Regulates fluid
and electrolyte balance
 Filters blood plasma
 Returns useful substances to
blood
 Eliminates waste
 Regulates
 Osmolarity of body fluids, blood
volume, BP
 Acid-base / electrolyte balance
 Secretes
Renin & erythropoietin
 Detoxifies free radicals &
drugs
 Reproductive System
 Main function – Provides
for perpetuation of the
species
88
 See Kidney Function Part 1 and Kidney Function Part 2
99
9
10
Children are not just small adults….
1010
1111
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Development of the Genitourinary System
12
Pediatric Differences – Urinary System
12
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Fluid & Electrolyte Balance Differences
 Incomparisontoadults,childrenareatagreaterriskforfluid&electrolyte
imbalance.Childrenhave:
 A proportionatelygreateramountofbodywater
 Requiremorefluidintakeandsubsequentlyexcretemorefluid
 A greaterbodysurfaceareaandahigherpercentageoftotalbodywater
 A greaterpotentialforfluidlossviathegastrointestinaltractandskin
 Anincreasedincidenceoffever,upperrespiratoryinfections,andgastroenteritis
 A greatermetabolicrate
 Immaturekidneysthatareinefficientatexcretingwasteproducts
 Kidneysthathaveadecreasedabilitytoconcentrateurine
 Increasedriskfordevelopinghypernatremiabasedontheirinabilitytoverbalizethirst
13
14
Pediatric Differences: Urinary System
 Allnephronspresentatbirth
 Renalgrowth
 Mostduringfirst5yrs
 Fullsizebyadolescence
 Renalefficiencyincreasesaschildmatures
 Kidneyfunctionisimmatureuntilafter2yearsofage
 Glomerularfiltration&absorptionimmature
 Infantsmorepronetofluidvolumeexcess&dehydration
 Lessefficientregulatingelectrolyte&acid-basebalance
1414
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Urinary Output
 Urinaryoutputperkilogramofbodyweightdecreasesas
childagesbecausethekidneysbecomemoreefficient
 Infants 2-3mL/kg/hr
 Toddler/Preschooler 2mL/kg/hr
 SchoolAge 1-2mL/kg/hr
 Adolescent 0.5-1mL/kg/hr
1515
1 gram diaper weight = 1 mL of urine
16
Bladder
 Bladdercapacityincreaseswithage
 15to50mLatbirth
 700mLinadolescence
 Estimate bladdercapacity(inounces)–add2tochild’sage
1616
17
Pediatric Differences – Reproductive System
17
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Pediatric Differences: Reproductive System
 Infemaleinfants,theexternalgenitaliamaybeprominentdueto
maternalestrogen
 Labiaminoramayprotrudebeyondlabiamajora
 Testiclesmayappearlargeatbirthinproportiontosizeofinfant
 Mayfailtomoveintothescrotum,causingundescendedtestes
 Theforeskinmaybetightatbirth,causing phimosis
 Thesexorgansdonotmatureuntilonsetofpuberty
 Secondarysexcharacteristicsoccurwithonsetofpuberty
18
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History & Physical
19
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Terms Commonly Used to Describe Urinary Dysfunction
 Dysuria:Difficultyinurination
 Frequency:Abnormalnumberofvoidings inashortperiod
 Urgency:Urgetovoidbutinability todoso
 Nocturia:Awakening duringthenighttovoid
 Enuresis:Uncontrolled voidingafterbladdercontrolhasbeen
established (bedwetting)
 Polyuria:Increasedurineoutput
 Oliguria:Decreased urineoutput
20
21
Focused Health History
 Mother’s pregnancy/ child’s birth history
 Family history: GU-specific disorders
 Review of fluid intake (including type of fluid)
 Urinary tract infections, fevers of unknown origin, dysuria
 Toilettraininghistory,voidingandbowelhistory,voidinghabits(e.g.,positioningduringvoiding)
 Any problems or changes with voiding (e.g., nocturia or enuresis)
 Rectum/ genitalia: any rashes, sores, or discharges
 Male children: circumcision status, prepuce issues, inguinal bulge/ scrotal swelling,
failure of testes to descend
 Females (if appropriate):
 Menstrual History – menarche, LMP, interval, regularity, duration, amount of flow, dysmenorrhea
 Obstetrical History - Gravida, Term, Para, Abortion, Live, Stillbirth (GTPALS)
 ****For adolescents, ask about sexual activity with parents out of room****
21
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Urinary Symptoms
 Enuresis(bedwetting)
 Newonsetincontinence
 Frequency,urgency,quantity
 Dysuriaanditstimingduringvoiding(atbeginningorend,throughout)
 Changeincolorandodorofurine
 Hematuria
 Presenceofstonesorsedimentintheurine
 Toilettrainingproblems
22
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Toilet Training Readiness
 Children<2yrsgenerallycannotmaintainbladdercontrol
 12months:nocontroloverbladder
 18to24months:somechildrenshowsignsofreadiness
 Somechildrenmaynotbereadyuntilaround30months
 Thepotty-trainingyearsareespeciallyriskyfordevelopingUTI
 Remindchildtovoidoftenevenifhe/sheisnothavingaccidents
 Remindfemalechildrentowipefromfronttoback
 Achildwhoisuncircumcisedshouldbetaughtatpottytraininghowto
graduallyandgentlyretracttheprepuceforvoidingandhygiene
2323
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Review Question
 Amotherisinquiringaboutherchild'sabilitytopottytrain.
Whichofthefollowingfactorsisthemostimportantaspect
oftoilettraining?
A. Theageofthechild
B. Thechild’sabilitytounderstand instructions.
C. Theoverallmentalandphysicalabilities ofthechild.
D. Frequentattemptswithpositivereinforcement.
25
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Anomalies & Diseases: Genitourinary
 Congenital/chromosomalanomalies(e.g.,singleumbilical
artery,low-setears,eartags);ambiguousgenitalia
 Cystitis,pyelonephritis,renaldisease
 GUsurgeryorprocedures
 Male:
Phimosis,cryptorchidism, hydrocele,testiculartorsion
26
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Single Umbilical Artery
Associated with
increased incidence of
urogenital
abnormalities
27
28
Low-Set Ears & Urinary Tract Anomalies
28
Suspect urinary
tract/ kidney
anomalies
29
Skin Tags/ Preauricular Sinus
29
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Assessment of the Genitourinary System
 Review:AssessingtheAbdomenforShape,Bowel
Sounds,andUnderlyingOrgans(pp.143-145)
 Review:AssessingtheGenitalandPerinealAreasfor
ExternalStructuralAbnormalities(pp.145-149)
30
See video “Pediatric Assessment” 24:07 – 25:47
See video “Physical Exam & Health Assessment: Child”
17:08 – 18:49
3131
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Nursing Diagnoses
 UrinaryIncontinence
 ImpairedUrinaryElimination
 UrinaryRetention
 ExcessFluidVolume
 RiskforDeficientFluidVolume
 RiskforImbalanced FluidVolume
 RiskforElectrolyteImbalance
 Toileting Self-CareDeficit
3232
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GU Process Focus
 Dailymonitoringofintake/outputandweightarevitalinassessingalterationsinfluid-
electrolytebalanceinthepediatricpatient
 Assessvitalsigns,notingthatbloodpressureisoftenelevatedwithglomerulonephritis
andnephroticsyndrome
 Monitorserumelectrolytes,creatinine,andBUNlevels(arisingcreatinineandBUN
suggestspoorrenalfunctioning)
 Measureheight,weight,andbodymassindex(failuretothrivecanbeassociated
withurinarytractinfectionsininfancyandincreasedweightcanbeassociatedwith
nephroticsyndrome)
 Noteearpositionandformation(low-setorabnormalearsmaybeanindicationof
congenitalrenalconditions)
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Diagnostic Tests
3434
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Laboratory Tests
 Urinalysis
 Urineculture
 Bloodureanitrogen(BUN)
 Serumcreatinine
 Creatinineclearancetest/glomerularfiltrationrate(GFR)
 Urinealbumin(proteinuria)
 Urineproteintocreatinineratio
 Basicmetabolicpanel/CBC
 Serumalbumin
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Urinalysis (UA)/ Urine Culture
 Specificgravity:1.001 – 1.035
 pH: 4.6 – 8.0
 Urinecolor
 Appearance
 Leukocyteesterace
 Protein
 Glucose
 Ketones
 Occultblood
 Bilirubin
 Urobilinogen
 Nitrite
3636
Which of these components (if positive) would indicate a urinary tract infection?
37
Urine Specific Gravity
 Reliable assessmentofpatient’s hydrationstatus
 1.001–1.035 Normalvalue
IncreasedUrineSG
Dehydration–diarrhea–excessivesweating-vomiting
DecreasedUrineSG
Excessivefluidintake–pyelonephritis-glomerulonephritis
3737
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Urine Collection
38
Application of urine collection bag
38
See Videos: Urine Samples Collection Pediatric
Urine Specimen Collection of Infant
39
Review Question
 Whichofthefollowinginterventionswillhelpobtainaccurate
urinalysisdata?
A. Forcefluidsto1000mLpriortospecimencollection.
B. Cleansethespecimencontainerwithpovidone-iodine(Betadine)prior
tocollectingthespecimen.
C. Allowtheurinetocooltoroomtemperaturebeforetakingittothelab.
D. Provideclient/parenteducationforspecimencollectionbeforethe
specimenisobtained.
3939
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Diagnostic Tests (p. 766)
 ComputedTomography(CT)
 Cystoscopy
 FunctionalRadionucleotideRenalScan
 IVP–IntravenousPyelogram
 RenalBiopsy
 RenalorBladderUltrasound
 VCUG–VoidingCystourethrogram
4040
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Computerized Tomography (CT Scan)
4141
Abdomen CT Scan
42
Cystoscopy
42
Invasive surgical
procedure
Visualizes bladder,
urethra, and ureter
placement
42
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Functional Radionucleotide Renal Scan
 Evaluates function of entire
urinary system, from
kidneys through bladder
 Nuclear medical imaging
 Requires use of a
radiopharmaceutical tracer
through an IV catheter
 Gamma camera takes
images (scintigraphy)
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Intravenous Pyelogram (IVP)
4444
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Intravenous Pyelogram (IVP)
45
Kidney function analyzed
Watch for allergic reaction
to dye
Dye can be toxic to kidneys
Push fluids
Monitor I & O
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Review Question
 Achildreturningtotheunitafteranintravenouspyelogram(IVP)
hasanordertodrinkextrafluids.Whenthemotherasksthe
purposeofthesefluids,thenurserespondsthatincreasedfluid
intakewill:
A. Overhydratethechild.
B. Increaseserumcreatinine levels.
C. Make-upforfluidlossesfromNPOstatusbeforetests.
D. Flushanyremaining dyefromtheurinarytract.
4646
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Renal Biopsy
4747
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Renal Bladder Ultrasound (RBUS)
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Voiding Cystourethrogram (VCUG)
4949
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Treatment Modalities
 Urinarydiversion
Stents
Drainagetubes
 Intermittent catheterization
Watchforlatexallergies
 Pharmacologicalmanagement
Antibiotics
Anticholinergicforbladderspasm(oxybutynin[DitropanXL])
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Urinary Tract Infection
5151
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Urinary Tract Infection (UTI)
 Infection in urinary system (urethra,
bladder, ureters, or kidneys)
 Cystitis: Lower UTI; urethra or bladder
 Pyelonephritis: Upper UTI; ureters, renal
pelvis, or kidneys
 Usually of bacterial origin (e coli);
characterized by inflammation
 Common in childhood; highest frequency
≤ 2 yrs of age
 Uncircumcised males: 10-fold incidence
 Prompt diagnosis/ treatment essential
 See video Urinary Tract Infection
5252
 The male and female urinary tracts are
similar except for length of urethra
53
UTI: Etiology/ Pathophysiology
 Urethralexposuretoorganismsortrauma
 Most commoncausativeorganism:Escherichiacoli
 Occursmorefrequentlyingirlsbecausethe short urethraislocatedcloseto anus
 Pathogensenterasanascendinginfection
 Teenager:sexualintercourseduetofrictiontrauma
 Urinarystasis
 Anatomicabnormalities;scarring/strictures
 Hydronephrosis;hypospadias,epispadias
 Neurogenicbladder–incompleteemptyingofbladder
 Intheolderchild:infrequentvoidingandincompleteemptyingofbladderorconstipation
 Vesicoureteralreflux(VUR)
 Urineflowsbackwardsintouretersandkidneys;providesmediumforbacteriatogrow
5353
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Review Question
Which of the following organisms is the most
common cause of UTI in children?
A. Staphylococcus
B. Klebsiella
C. Pseudomonas
D. Escherichiacoli
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UTI - Females
 More common (generally)
in females
 Short urethra
 Improper wiping
 Bubble baths
 Nylon under pants
 Current guidelines – renal
and bladder ultrasound with
first febrile UTI followed by
VCUG if indicated
 Second febrile UTI – VCUG
5555
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UTI – Males
 UTIs in males tend to be
complicated
 More common in males than
females during 1st 3 months of life
 Males 2-24 months:
 Febrile with first UTI
 Renal & bladder ultrasound –
hydronephrosis, scarring,
obstructions, masses
 2nd episode febrile UTI
 VCUG – vesicoureteral reflux
 Higher incidence of UTIs in
uncircumcised males
5656
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Uncircumcised Males
 Instructparentstogentlyretractforeskinforcleansing
 Donotforcetheforeskin
 Donotleaveforeskinretractedoritmayactastourniquet and
obstructtheheadofthepenisresultinginemergency
circumcision
5757
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UTI: Diagnostic Tests
 Urine for culture and sensitivity
 Clean catch
 Catheterization
 Suprapubic aspiration
 A Positive Test
 Bacteria colony ≥ 50,000 per mL
 Positive leukocyte esterace; positive nitrite tests; white blood cell
(WBC) casts
 Ultrasound: structural abnormalities, scarring
 Voiding cystourethrogram (VCUG): vesicoureteral reflux
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UTI: Clinical Manifestations
 Signs & symptoms not always clear (atypical presentation)
 Typical S & S of older children and adults – dysuria, frequency,
urgency, burning, hematuria – may not be present
 Newborn/ infant: unexplained fever; failure to thrive; poor feeding;
vomiting; diarrhea; foul-smelling urine; irritability; lethargy
 Fever of unknown origin (child ≤ 2 yrs): test for UTI
 Toilet-trained child: new onset incontinence, wetting accidents
 Upper UTI S & S: high fever, chills, abdominal pain, flank pain,
costovertebral-angle tenderness, vomiting, malaise (i.e., vague
feeling of general discomfort)
5959
See “Clinical Manifestations Urinary Tract Infection” – p. 768
60
Review Question
UTI: What are the differences between older
child/ adult S & S and infant-child S & S
60
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UTI: Collaborative Care
 Obtainurinespecimen(orbloodcultures)beforeantibiotics!
 ComplicatedUTI/pyelonephritis:hospitalization,IVfluids,parenteralantibiotics
 UncomplicatedUTI:oralantibiotictherapyfor10to14days
 Escherichiacoli,Enterococcus,Proteus,&Klebsiellamostcommonorganisms
 Amoxicillin/clavulanic(Augmentin),sulfamethoxazole/trimethoprim(Bactrim,Sulfa),
cephalexin(Keflex),cefixime(Suprax)
 Increasefluidintake
 Acetaminophen/ibuprofenforpain
 Repeaturinalysis–usuallyafter72hrsoftxtomakesuretxiseffective
6161
See “Prevention of Urinary Tract Infections” – p. 769
62
UTI: Nursing Education
 Antibiotics–takefullcourse
 Changediaperfrequently
 Teachgirlstowipefronttoback
 Encouragechildrentodrinkperiodicallyduringtheday
 Nobubblebaths
 Encouragefrequentvoiding
 Discourage“holding”urine
 Usecottonunderwear
 Menstruatinggirl– changepadevery4hours
 Whengirlsbecomesexuallyactive– urinateimmediatelyafterintercourse
6262
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Review Question
 Themostimportant nursingactivity inmanagingayoung
child diagnosed withurinarytract infection (UTI)isto:
A. Provideadequate nutrition toprevent dehydration.
B. Prevent enuresis.
C. Administer ordered antibiotics onschedule.
D. Restrictfluidsto provide kidneyrest.
6464
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Review Question
 Theparentsofachilddiagnosedwithupperurinarytract
infection(UTI)askthenursewhythechildneedsadaily
weight.Informulatingaresponse,thenurseincludesthatit
isimportantbecauseadailyweightwill:
A. Determineifthechild’scaloricintakeisadequate.
B. Indicatetheneedfordietaryrestrictionsofsodiumandpotassium.
C. Keeptrackofpossiblelossorgainoffluidretainedinbodytissues.
D. Tracktheamountoffluidingestedorallyeachday.
6565
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Bladder Exstrophy
Hypospadias & Epispadias
Obstructive Uropathy
Vesicoureteral Reflux
Structural Defects of the Urinary
System (usually hereditary)
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Bladder Exstrophy
 Exstrophy: turning inside out
 1 in 40,000 births
 Twice as common in males
 Congenital malformation in which
the abdominal and anterior
bladder walls do not fuse during
fetal development
6767
•Inside-outbladder;
•Mucosa(inside
lining)ofbladder
exposed
68
Bladder Exstrophy: Clinical Manifestations
 Visible defect revealing bladder
mucosa/ ureteral orifices through
open abdominal wall
 Constant drainage of urine;
excoriated skin
 Mass bright red tissue (bladder)
 Numerous additional congenital
anomalies: epispadias, short
penis, upward chordee, split
clitoris, forward-positioned anus,
low umbilicus, wide pelvis,
waddling gait
6868
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Bladder Exstrophy: Collaborative Care
 Multidisciplinary approach
 Surgery within 48 hrs after
birth to close the skin over
bladder and reconstruct male
urethra/ penis
 Urethral stents/ suprapubic
catheter to divert urine
 Further reconstructive surgery
between 6 mos to 5 yrs of age
 Requires lifelong follow-up
6969
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Before and After Surgical Repair
70
Details: http://www.pediatricurologybook.com/bladder_exstrophy.html
71
Goals of Treatment
 Closebladder/abdominalwall
 Preserverenalfunction
 Attainurinarycontrol
 Acceptableappearance/
functionofgenitals
 Sexualfunction
 Typical&normalchildhood
7171
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Nursing Care
 Pre-Op:Preventinfectionandtrauma
 Umbilicalcordtiedwith2.0silksuture(notumbilicalcordclamp)
 Bladdercoveredwithsterileplasticwrap;irrigatedwithwarmsaline
 Skinprotectedwithointmentorsealant
 Infantpositionedsupinewithdiaperunderneath
 Post-Op:
 Maintainproperalignment(noabduction);monitorperipheralcirculation;provide
meticulouswound/skincare
 Monitorrenalfunction;strictI&O;observeforsignsofobstruction;promotecomfort;
administerantibiotics
 Supportparents;promotebonding;guidance&dischargeteaching
72
ModifiedBryant’straction
73
Review Question
Whichofthefollowing positions would best facilitate
healing fortheinfant after bladder exstrophy repair?
A. Supine,legssuspendedverticallywithlegsclosetogether
B. Leftside-lyingposition
C. Rightside-lyingposition
D. Low-Fowler’s,legsbentatkneeswithwedgebetweenlegs
73
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Long Term Complications
 Urinaryincontinence
 Infection
 Bodyimage
 Inadequatesexualfunction
7474
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Hypospadias & Epispadias
75
Hypospadias
EpispadiasEpispadias
Hypospadias
Recurrent UTIs are a complication of both conditions
 Hypospadias: Abnormal opening of urethra on
underside of penis rather than tip
 Common congenital anomaly of penis
 Ranges from mild to severe
 Undescended testes may be present
 Downward curvature of penis (chordee)
 Might interfere with fertility
 Epispadias: Abnormal opening of urethra
above tip of penis or between clitoris and
labia (girls)
 Rare congenital anomaly (girls & boys)
 Milder expression of bladder exstrophy
 Short broad penis, upward curvature
 Abnormal clitoris, labia, wide pelvis (girls)
7676
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Hypospadias
 Ventral surface
 Below glans penis
Epispadias
 Dorsal surface
 Above glans penis
Hypospadias & Epispadias
77
Hypospadias & Epispadias: Collaborative Care
 Diagnosis: PrenatalUS,examination atbirth
 Circumcisionnotrecommended(foreskinmaybeneededfor
reconstructive surgery)
 Notreatment necessaryinmilddisorder
 Hypospadiasrepair:4-18mos(earlyintervention preferred)
 Epispadiasrepair:12-18mos(allowsbladdertimetoenlarge)
 Post-op:Forcefluids,keepurinarystentpatent,leavebandagein
place,notubbathing untilstentisremoved
7777
See “Caring for the Child After Hypospadias and Epispadias Repair” – p. 772
78
Review Question
 Shortlyafterbirth,thenewbornwasfoundtohaveepispadias.Priorto
delivery,themotherhadsignedpermissionforacircumcision.The
obstetricianisplanningtoperformthecircumcisionimmediatelyafter
delivery.Thenurseexplainstothemotherthatthecircumcisionwillnot
bedoneatthistimebecause:
A. Themothershouldnothavesignedconsentbeforedelivery.
B. Thefatheralsoneedstosignpermissionforsurgery.
C. Theprepucewillbeusedforthesurgicalcorrection.
D. Theriskofinfectionisgreaterwithachildwithepispadias.
7878
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Hypospadias & Epispadias: Nursing Care
 Keeptheareacleantopreventinfection
 Assessforpostsurgicalcomplications
 Monitorforsignsofinfection
 WatchforevidenceofUTI
 Assesspain(oxybutyninrelievesbladderspasms)
 Encouragetheparentstoexpresstheirfeelings/concernsandprovide
emotionalsupport
 Dischargeinstructions: Bandagedressingcare,careofstent,activity
restrictions,nutrition,paincontrol,andsigns/symptomsofcomplications
79
See “Caring for the Child After Hypospadias and Epispadias Repair” – p. 772
80
Review Question
 Aninfanthasbeenadmittedfortreatmentofhypospadias.
Nursingmanagement ofthechildandfamilyincludes:
A. Parenteducation regarding steroidtherapy.
B. Addressingparentalanxietyrelatedtofunctioning and
appearanceofthepenis.
C. Homehealthteaching ofproperstraightcatheterization
techniques.
D. Monitoring forsignsandsymptomsofnephroticsyndrome.
8080
81
Double-Diapering Technique After Surgery for
Hypospadias/Epispadias Repair
81
82
Review Question
 Themotherofaninfantwhounderwentsurgerytorepair
hypospadiasasksthenursewhytheinfantisdouble-
diapered.Thenursewouldrespondthatthismethodof
diapering:
A. Protectstheurinarystentthathasbeenputinplace.
B. Adequatelymeasurestheurinaryoutput.
C. Providesformaximumabsorptionofurine.
D. Providesoptimalprotectionofperinealskinfrominfectedurine.
8282
83
Hydronephrosis/ Hydroureter (Obstructive Uropathy)
 “Water on kidney” enlarges renal
pelvis, damages nephrons
 Mechanical blockage/ obstruction in
urinary tract; most often unilateral
 Congenital malformations: ureters,
ureteral valves, bladder, urethra
 Can lead to: nephron destruction,
HTN, ↓ ability to conserve Na+,
metabolic acidosis, recurrent UTIs,
progressive irreversible renal failure
 Goal: maintain integrity of kidney until
normal urinary flow established
 Early diagnosis essential (US)
8383
84
Common Sites of Obstruction in Upper/ Lower
Urinary Tract (Congenital Malformations)
84
84
 Why would damage
from the posterior
urethral valves be
potentially worse
than other
obstructions?
85
Review Question
 Aparentasksthenursewhatwilleventuallyhappeniftheinfant
doesnothavehiscongenital hydronephrosistreated.Themost
accurateanswerbythenursewillbewhichofthefollowing?
A. “Ifthehydronephrosisisnottreated,thechildcandevelopbladdercancer.”
B. “Theinfantcanbecomedangerouslyhypotensivebecauseoftheobstructionto
urineflow.”
C. “Smallcalciumstonescanoccurasaresultofuntreatedhydronephrosis,
causingfurtherobstruction.”
D. “Untreatedhydronephrosiscanleadtoirreversiblekidneydamageand
eventualkidneyfailure.”
85
86
Hydronephrosis: Clinical Manifestations
 Distended bladder/abdomen
 HistoryofUTI:flankpain,feverandchills
 S&Srenalinsufficiency: decreaseinurinaryoutflow,swelling,
hypertension, anemia,poorappetite; decreasedabilityofkidney
toconservesodiumandconcentratetheurine
 NeonatemaypresentasUTI
 Outerearabnormalities, singleumbilical artery
 Anolderchildmaybeasymptomatic exceptforFTT
8686
87
Review Question
 Anurseisreviewingapatient’schartandnoticesthatthechild
suffersfromhydronephrosis. Whichofthefollowing wouldthe
nurseexpecttoseewiththispatient?
 A.Swollenkidneyduetourinenotdraining fromkidney
 B.Dehydrationfromspittingupandseveralloosestools
 C.Profuseurinationandurinaryfrequency
 D.Spinalcorddefectcausinginability toemptybladder
87
88
Hydronephrosis: Diagnostics
 Ultrasound of
kidneys/bladder
 VCUG: voiding
cystourethrogram
 Diuretic renography with
radioisotope
 Requires use of a
radiopharmaceutical tracer
& intravenous furosemide
through IV
8888
89
Hydronephrosis: Collaborative Care
 Goalsofcorrection:Preserverenalfunction,lowerpressurewithin
collectionsystem
 Temporaryurinarydiversionmaybeneededtorelievethepressure
 Surgicaltreatment:insertionofureteralstents,nephrostomy tube;
pyeloplasty; valverepair/reconstruction
 Nephrectomy ifrenaldamageisnotreversible
 Nursingcare:support/educateparents;monitorVS,I&O;
observeforsignsofurinaryretention; administermedications
8989
90
Vesicoureteral Reflux (VUR)
 Regurgitation of urine from the bladder into the ureters due to
faulty valve mechanism at the ureterovesicular junction
 Predisposes child to: UTIs; pyelonephritis; hydronephrosis
 White children, girls, children ≤ age 2; tends to run in families
 Assessment findings: same as for UTIs/ FTT
 Diagnostic tests: kidney/ bladder US, VCUG, nuclear scan
 Goals: prevent pyelonephritis, renal scarring, chronic renal failure
 Tx: Long-term daily low-dose antibiotic prophylaxis; valve repair or
reconstruction; endoscopic surgery; surgery to re-implant ureters
9090
91
Ureteral Reflux
9191
92
Vesicoureteral Reflux: Nursing Care
 Assist with preoperative studies as needed
 Provide postoperative care:
 Observe for signs of infection
 Monitor VS, I & O
 Monitor drains; may have one from bladder and one from each ureter (ureteral
stents)
 Check output from all drains (expect bloody drainage initially) and record
carefully
 Observe drainage from abdominal dressing; note color, amount, frequency
 Administer medication for bladder spasms as ordered
 Support/ educate parents
93
Nephrotic Syndrome
Acute Poststreptococcal
Glomerulonephritis
RenalFailure
RenalReplacement Therapy
Renal Disorders: Acute, Chronic, &
Structural Causes
9393
Nephrotic Syndrome/ Nephrosis
(Minimal Change Nephrotic Syndrome)
94
 Clinical state characterized by massive proteinuria, edema,
hyperlipidemia, and hypoalbuminemia
 Alterations in the glomerular membrane allow proteins, especially
albumin, to pass in urine resulting in decreased serum osmotic
pressure contributing to edema
 Most common presentation of glomerular injury in children
 Constellation of clinical findings, not a disease (all a result of massive
renal losses of protein)
 Most common form: Minimal Change Nephrotic Syndrome
(MCNS); accounts for 85% of all pediatric cases
 Peak incidence 2-6 years old; twice as frequent in boys
 Etiology unknown; autoimmune process suspected
 See video Nephrosis (Nephrotic Syndrome)
95
Review Question
96
Nephrotic
syndrome is
caused by damage
to which part of the
nephron?????
MinimalChangeNephroticSyndrome/ Effacement of foot processes
97
Contrast Between Normal Glomerular Anatomy &
Changes of Nephrotic Syndrome (p. 818)
97
Massiveamountsofproteinare
excretedinurine
Edemaresultsfromdecreased
oncoticplasmapressure,renin-
angiotensin-aldosteroneactivation,&
antidiuretichormonesecretion
Loweralbuminbloodlevel
stimulatesthelivertogeneratelipids
&excessiveclottingfactors
Loss of podocyte foot processes = MASSIVE PROTEINURIA
MCNS: Clinical Manifestations
 Pitting edema (around the eyes, scrotum, abdominal ascites,
dependent areas, lower extremities)
 Weight gain over a short period (from fluid retention)
 Pale, poor appetite, irritability, fatigue, abdominal discomfort,
vomiting, diarrhea
 Pulmonary edema, effusions
 Malnutrition, growth failure
 Foamy appearance of urine
 Normal or slightly elevated BP
98
Periorbital, scrotal edema
Nephrotic Syndrome: Anasarca
99
Describe the fluid shifts in
Anasarca….
What sorts of health
complications do you anticipate?
100
MCNS: Diagnostic Evaluation
 Proteinuria (First morning urine sample)
 Urine protein/ creatinine ratio > 2
 Hypoproteinemia
 Serum albumin < 2.5 g/dL
 Hyperlipidemia/ Lipiduria
 ↑ Cholesterol, triglycerides; lipids in the urine
 Hypercoagulability (PT/PTT/INR/ antithrombin III)
 Basic metabolic panel (BMP)
 BUN/ Creatinine normal unless renal damage
 Hyponatremia (low serum sodium)
 Kidney biopsy
100100
Monitor serum albumin and electrolytes, particularly potassium and sodium.
Review Question
Which of the following signs and symptoms are
characteristic of Minimal Change Nephrotic
Syndrome?
A. Gross hematuria, proteinuria, fever
B. Hypertension, edema, fatigue
C. Poor appetite, proteinuria, edema
D. Body image change, hypotension
101
102
MCNS: Collaborative Care
 Goals of treatment: minimize edema; decrease urinary protein loss; prevent
infection; & prevent toxic medication side effects
 Trial of corticosteroids: 1st step in treatment
 Oral prednisone minimum of 6 months
 If responsive, urine protein levels fall
 Relapse/ remission not obtained: immunosuppressive agents
 Diuretic therapy
 Intravenous albumin followed by furosemide
 Metolazone 30 minutes before furosemide (for resistant edema)
 Antihypertensive therapy: ACE – to help reduce proteinuria
 Balanced nutrition, low-salt diet
 Prevent or treat any infection
102
MCNS: Nursing Care
 Nursing goals: manage symptoms; prevent
complications; meet nutritional needs; address
emotional needs of child/ family
 Provide rest, cluster care
 Monitor I&O, specific gravity, proteinuria
 Daily weights on same scale and amount of
clothing
 Monitor edema and measure abdominal girth
 Promote pulmonary health through position
changes, activity as tolerated, deep breathing &
coughing exercises, spirometer use
103
MCNS: Nursing Care
104
 Monitor VS, especially temperature for signs of infection
 Encourage small, frequent meals within restriction
guidelines
o Salt & fluids may be restricted during edematous stage
 Prevent skin breakdown & pressure sores; turn frequently
 Administer medications as ordered; carefully monitor side
effects
 Prevent infection: meticulous hand hygiene, vaccinations,
prevent contact with infectious persons
Review Question
 A nurse is assigned to care for a client with
nephrotic syndrome. The nurse assesses which
important parameter on a daily basis?
A. Weight
B. Albumin levels
C. Activity tolerance
D. Blood urea nitrogen (BUN) level
105
Corticosteroids: Side Effects
106
 Immunodeficiency
 Hirsutism
 Moonfacewithruddycheeks
 Acne
 Dorsocervicalfatpads
 Ecchymosis(easybruising)
 Truncalobesity
 Moodswings–inability tosleep
106106
107
Moon Face
107
High-dose
corticosteroid
therapy produces
a characteristic
“moon face”
appearance
107
108
Before and After
108108
109
Review Question
While a child is receiving prednisone (Orapred) for
treatment of nephrotic syndrome, it is important for
the nurse to assess the child for:
A. Infection.
B. Urinaryretention.
C. Easybruising.
D. Hypoglycemia.
109109
110
Review Question
 Achildhasrecurrentnephroticsyndrome.Themotherreportstothe
nursethatsheisoverwhelmedwiththecareofherchild.Afterthenurse
discussesoptionswiththemother,whichstatementbythemother
indicatescontinuedcopingdifficulties?
A. “Ijoinedasupportgrouplikeyousuggested.Ihopeitdoessomegood.”
B. “I’mgoingtoaskmymother-in-lawtocomeonaregularbasistoallowme
anafternoonout.”
C. “Myhusbandhasagreedtohelpmemanagemyson’smedication.”
D. “We’regoingtoskiphisdietaryrestrictionsonedayaweektoallowusboth
somerelaxation.”
110110
Acute Poststreptococcal Glomerulonephritis
111
 Glomerulonephritis = inflammation of the glomerulus
 Autoimmune immune-complex disorder occurring 10-21 days after
group A beta-hemolytic streptococcal infection (upper respiratory,
pharyngitis, tonsillitis, impetigo)
 Children ages 2-6 yrs; more common in boys than girls
 Sudden appearance of hematuria,proteinuria, red blood cell casts in the
urine, edema, and hypertension with or without oliguria
 Immune complexes from recent strep infection become entrapped in
glomerular membrane; immune activity targeted at the glomerulus
 Inflammation, tissue injury, and obstruction of glomerular capillaries
 Reduced glomerular filtration rate (↓GFR)
 Sodium and water retained: edema and hypertension
Group A Streptococcal Infection Manifestations
112
Review Question
 A client has been admitted to the hospital with a
diagnosis of acute glomerulonephritis. During history-
taking the nurse first asks the client about a recent history
of:
A. Bleeding ulcer
B. Deep vein thrombosis
C. Myocardial infarction
D. Streptococcal infection
113
114
Infection from group A beta-hemolytic Streptococcus leads to an immune
response that causes inflammation and damage to glomeruli
114
Protein&redblood
cellsareallowedtopass
throughglomeruli
Bloodflowtoglomeruli
isreduceddueto
obstructionwithdamaged
cells
Renalinsufficiency
results,leadingto
retentionofsodium,
water,&waste
IMMUNE ACTIVITY targeted at GLOMERULUS
Vessels
clogged
with
cells
Glomerular Capillaries Clogged With Cells
115
 Immune complexes
(mixtures of antibodies
and antigens) are
filtered out of the
bloodstream and
become trapped within
the glomeruli
 Body responds by
activating its immune
defenses, resulting in
further damage to the
glomeruli
116
Acute Poststreptococcal Glomerulonephritis:
Clinical Manifestations
 Gross hematuria/ RBC casts
 ↓GFR
 Oliguria
 Azotemia (elevated nitrogenous
wastes in blood)
 Hypertension
 Periorbital edema
 Brown foamy frothy urine
 Mild/moderate proteinuria
116116
Tea- or cola-colored urine
The most common clinical sign of glomerulonephritis is blood in the urine
117117
117
118
 Dx: streptozyme test; ↓ H & H; ↑ BUN, creatinine; hematuria, proteinuria,
RBC casts; ↑ erythrocyte sedimentation rate
 Tx goals: relief of symptoms, supportive therapy
 Monitor urinary output, daily weights, blood pressure, & serum electrolytes
 Limited activity, bed rest
 Diuretics such as furosemide (Lasix) to reduce fluid overload
 Antihypertensive drugs to treat increased blood pressure
 Antibiotics (penicillin) if a streptococcal infection is documented or detected
 Restriction of fluids to replace insensible losses
 Low-sodium, low protein diet (during acute phase)
118118
Acute Poststreptococcal Glomerulonephritis:
Collaborative Care
 Nursing care: monitor fluid status, prevent infection, prevent skin
breakdown, meet nutritional needs, and provide emotional support to the
child/ family
 Monitor: VS, I & O, daily weight; abdominal girth; watch for signs of renal
failure, including decreased (less than 1 mg/kg/hour), or no urine output
 Monitor: signs of infection, including fever, malaise, & elevated WBC
 Enforce activity limitations, bed rest during acute phase; cluster care
 Institute sodium restrictions for the child with hypertension or edema
 Educate parents: dietary restrictions (sodium, potassium, & fluid intake)
 Administer diuretics/ antihypertensive medications as needed
 Provide emotional support
119
Acute PoststreptococcalGlomerulonephritis:
Nursing Care
120
Review Question
When reviewingaurinalysisreport ofaclientwithacute
glomerulonephritis, the nurse wouldexpecttonote:
A. Decreased creatinine clearance.
B. Decreased specificgravity.
C. Hematuria.
D. Decreased erythrocyte sedimentation rate(ESR).
120120
121
Acute Renal Failure/ Acute Kidney Injury
 Life-threateningdisorder
 Kidneysunableto
 Clearwastes
 Regulatefluidvolume,sodiumbalance, &acid-basehomeostasis
 Pre-renal,resultingfromimpairedbloodflow
tooroxygenationofthekidneys
 Renal,resultingfrominjurytoormalformation
ofkidneytissues
 Post-renal,resultingfromobstructionof urinaryflowbetweenkidney &meatus
 Seevideo3MinuteAcuteRenalFailureforNursingStudents
121121
Suddenlossofrenalfunction
122
123
Review Question
Thenurseadmits children withthe following diseases to
theunit.Which disease places the childatriskforthe
development ofacuterenal failure (ARF)?
A. Leukemia.
B. Cryptorchidism.
C. Nephroticsyndrome.
D. Phenylketonuria.
123123
124
The initial kidney injury is usually associated with an acute condition such as sepsis, trauma, and
hypotension, or is result of treatment for an acute condition with nephrotoxic medication
124
Injurytothekidneycan
occurbecauseofglomerular
injury,vasoconstrictionof
capillaries,ortubularinjury
Allconsequencesof
injuryleadtodecreased
glomerularfiltration&
oliguria
Acute Renal Failure/ Acute Kidney Injury
125
Review Question
Achild has been admitted in renal failure.The nurse
would expect to find:
A. Decreased BUN.
B. Adequate glomerular filtration.
C. Azotemia and oliguria.
D. Polyuria and elevated creatinine clearance.
125125
Newborn Causes Childhood Causes
 Congenital anomalies
 Hypotension
 Complication ofopenheart
surgery
 Dehydration
 Glomerulornephritis /
NephroticSyndrome
 Nephro-toxicity /drugtoxicity
Acute Renal Failure
126
127
Review Question
 Achildisadmitted tothenursingunitwithacuterenalfailure
(ARF).Whenreviewingthenursinghistory,thenursenotesa
historyofallofthefollowing medicalconditions. Whichismost
likelytohaveprecipitated theonsetofARF?
A. Chickenpox.
B. Influenza.
C. Dehydration.
D. Hypervolemia.
127127
128
Acute Renal Failure: Clinical Manifestations
 Suddenonset
 Oliguria
 Urineoutputlessthan0.5to1mL/kg/hour
 Darkurine
 Volumeoverloadduetoretainedfluid
 Hypertension,edema,shortnessofbreath
 ElectrolyteImbalances–seechart,p.827
 Acidosis
 Nonspecificsymptoms:nausea,vomiting,lethargy
128
See “Clinical Manifestations” – p. 783
129
Diagnostic Tests
 Basic Metabolic Panel (BMP)
 BUN and Creatinine elevated
 Serum Potassium elevated
 Decreased CO2
 CBC
 Decreased RBCs, H & H due to deficient erythropoietin
 ABG
 Decreased pH
 Decreased Bicarbonate (HCO3−)
 GFR (glomerular filtration rate) decreased – most sensitive
indicator of glomerular function
129129
130130
130
The Most Deadly Electrolyte Imbalance…
131
Review Question
 The child with acute renal failure has a serum potassium
of 6.0 mEq/L. The nurse would plan which of the
following as a priority action?
A. Check the sodium level
B. Place the child on a cardiac monitor
C. Encourage increased vegetables in the diet
D. Allow an extra 250 mL of fluid intake to dilute the
electrolyte concentration
132
133
134
Review Question
The priority concern for the nurse in assessing a
child with acute renal failure (ARF) should be to
look for which electrolyte imbalance?
A. Potassium.
B. Sodium.
C. Calcium.
D. Phosphorous.
134134
135
Urea or BUN
Urea is normally freely filtered throughthe renal
glomeruli, with a small amount reabsorbedin the
tubules andthe remainder excreted in the urine
Decrease or increaseinthe valuedoes nottell the
cause: pre-renal, post-renal or renal
Elevated BUN just tells youthe urea isnot being
excreted by the kidney, not why
135135
136
Creatinine
Creatinine is a very specific indicator of renal
function
If kidney function is decreased / creatinine level will
be increased
Conditions that increase levels: glomerulonephritis,
pyelonephritis or urinary blockage
136136
137
Creatinine Levels
Adult female: 0.5-1.1 mg/dL
Adult male: 0.6-1.2 mg/dL
Adolescent: 0.5-1.0 mg/dL
Child: 0.3-0.7 mg/dL
Infant: 0.2-0.4 mg/dL
Newborn: 0.3-1.2 mg/dL.
137137
138
Acute Renal Failure: Collaborative care
 Treatmentdependsontheunderlyingcause
 Preventpermanentrenaldamage
 Reducesymptoms
 Supportivecareuntilrenalfunctionreturns
 Medications– seechart,p.827
 Avoidnephrotoxicmedications(NSAIDs.,radiocontrastagents,
aminoglycosideabx)
 Dietaryrestrictions–seeTable26-5,p.831
 Dialysisifindicated
 Seevideo4NursingInterventionsforAcuteRenalFailurePart1andPart2
138138
139
Acute Renal Failure: Nursing Care
 Provideemotional supportforchildandfamily
 MonitorVS,I&O,dailyweights,serumelectrolytes
 Administermedications asordered
 Monitornutritional intake–sodium,potassium,andphosphorus
mayneedtoberestricted
 Meetfluid,electrolyte,andnutritional needs
 Preventinfections andcomplications
 Dischargeplanning &homecareteaching
139
140140
141
Review Question
Afour-year-old childhasbeen diagnosed withrenal
failure.Thenurse would ensure thatthedietforthischild
wouldcontain:
A. Foodshighinpotassiumandsodium.
B. Adequatecaloriestooptimizegrowth.
C. Foodshighincalciumcontenttopromotebonegrowth.
D. Increasedfluidintaketoflushtheurinarysystem.
141141
142
Review Question
Ateenager inacuterenal failure has anorderforfluid
restriction. What assessment criteriawouldindicate that
insufficient fluids arebeing administered tothischild?
A. Increasedweightwithdecreasedserumpotassiumlevels.
B. Proteinuria.
C. Hypernatremiawithweightloss.
D. Decreasedpulse.
142142
143
Chronic Renal Failure
 Progressive,irreversibledeteriorationofrenalfunction, usually
overaperiodofmonthsoryears
 Fivestages:ESRDfinalstage
 Etiology:congenitalanomalies, hereditary diseases,
infections,glomerulonephritis
 Signsandsymptoms
 Lethargy,fatigue,anorexia,nausea,vomiting,hypertension,growthretardation,edema,volume
overload,hyperkalemia,metabolicacidosis,anemia,bonedisease(renalosteodystrophy),
cardiovasculardisease,centralnervoussystem abnormalities, delayedsexualmaturation
 Seevideo4StagesofChronicRenalFailure&ESRD
143
144
Effects of Chronic Renal Failure
 Growthdelays
Duetoanemia,metabolismdisturbances,decreasedcaloricintake,
metabolicacidosis
 Cognitivedelays
Duetodecreasedalertness,fatigue,poorschoolattendance
 Socialdevelopmentimpairment
Duetoalterationofbodyimage,delayedonsetofpuberty,sideeffects
ofmedications
144144
Chronic Real Failure: Collaborative Care
 Dx:BUN/serumcreatinine(mostimportanttests);serumelectrolytes,
bicarbonate;CBC;urinalysis(proteinuria,hematuria,pyuria,sp.gravity,hyaline
casts);estimationofGFR;US/radionuclidestudies;renalbiopsy
 Treatmentdependsoncourseofthedisease
 Medications -seechart,p.830
 Diettherapy–limit potassium,phosphorus,sodium(seeTable26-5,p.831)
 Proteinrestrictedonlytotherecommendeddailyallowanceforchildren
 Preventionandtreatmentofcomplicationsofdecreasedkidneyfunction(e.g.,anemia,bonedisease,
cardiovascularmanifestations,hypertension,growthfailure)
 Avoidnephrotoxicmedications(NSAIDs.,radiocontrastagents,aminoglycosideabx)
 Renalreplacementtherapy,ifsigns/symptomsofuremiaarepresent
 Regularlifelongfollow-up
145
146146
146
147
Review Question
Achild has been diagnosed with chronic renal
failure.The nurse would question the medical
order for:
A. Aqueous penicillin.
B. Gentamicin (Garamycin).
C. Antihypertensives.
D. Corticosteroids.
147147
148
Review Question
A 10-year-old child has just been diagnosed with
end-stage renal disease. The nurse gives the child
instructions in which foods to avoid, including:
A. Eggs
B. Carrots
C. Rice
D. Spinach
149
Review Question
Which of the following should be considered in the
diet of the child with end-stage-renal-disease
(ESRD)?
A. Limit fluid
B. Limit vitamin D-rich food
C. Limit calcium-rich food
D. Limit carbohydrates
150
Chronic Renal Failure: Nursing Care
 Provideemotionalsupport tochildandfamily
 Assesshydrationstatuscarefully:I&O,dailyweights
 Fluidrestrictions&dietaryrestrictionson potassium,phosphorus,&sodium
 Maintainstrictsteriletechnique&watchforsignsofinfection
 Monitorserumelectrolytelevels;H&H
 Givemedications&monitorforsideeffects
 Providesmall,frequentfeedings;presentmealsattractively;developmeal
plansthatfitarestricteddiet
 Dischargeplanningandhomecareteaching
151
Review Question
 An adolescent with renal failure is receiving epoetin alfa
(Epogen) to support erythropoiesis. The nurse questions
the teenager about compliance with taking which of the
following medications that supports red blood cell (RBC)
production?
A. Iron supplement
B. Zinc supplement
C. Calcium supplement
D. Magnesium supplement
152
153
Renal Replacement Therapy:
Peritoneal Dialysis
 Peritonealdialysis-child’sownperitonealcavityactsasthesemi-permeable
membraneacrosswhichwaterandsolutesdiffuse
153
•SeevideoPeritonealDialysis(NursingConsiderations,Risks,PatientTeaching)
Peritoneal Dialysis
 Softcatheterisusedtofillthe
abdomenwithadialysissolution
 Solutioncontainsdextrose(1.5,2.5,
or4.25%)thatpullswasteandextra
fluidintotheabdominalcavity
 Osmoticpressureofglucosein
solutiondrawsfluidfromvascular
spacesintotheperitoneum,making
availableforexchange/elimination
ofexcessfluid&wastes
 Dialysisfluidisthendrained
154154154
155155
155
Peritoneal Dialysis: Nursing Care
 Assistparentsinlearningperitonealdialysis
 Makesurestrictsteriletechniqueisusedatalltimesduringcatheter
placementandperitonealdialysis(handhygiene,gloves,masks)
 Monitorthechild’sresponsetothetherapy
 Assessforcomplications:bleedingfromthecathetersite,signsof
infectionatthecathetersite,peritonitis,abdominalhernia
 Maintainpatencyoftheperitonealdialysiscatheter:keepitinplace,
withoutkinksorpulling,andwiththefluidbagsatthecorrectlevel
 Noteifreturningdialysatesolutionhasunusualcolororiscloudy
156
See “Nursing Care Plan: Child Receiving Home Peritoneal Dialysis” – p. 792
157
Review Question
Anappropriate nursingdiagnosis forachildreceiving
peritoneal dialysisis:
A. Fluidvolumedeficitrelatedtosodiumandwaterretention.
B. Imbalanced nutrition,greaterthanbodyrequirements relatedto
increasedhunger.
C. Riskforinfectionrelatedtoinvasiveproceduresanddiminished
immunefunctioning.
D. Alteredrenaltissueperfusion relatedtohypervolemia.
157157
158
Renal Replacement Therapy:
Hemodialysis
 Inhemodialysis,amachinefilterswastes,saltsandextrafluidfromtheblood;
thecleanbloodisthenreturnedtothebody
 Requiresstricttreatmentschedule;adherencetomedications/dietrestrictions
 Done3timesaweekfor3to4hoursatadialysiscenter
 Attheonset,achildmayexperienceseveralsideeffects(disequilibrium
syndrome)—hypotension,dizziness,weakness,nausea,ormusclecramps
 SeevideosHemodialysis(Labs,H&H,Cautions)
 WhatDoesaKidneyDialysisAccessLookLike?
 HemodialysisandHowItWorks
158
159
Hemodialysis: Types of Access
159159
Hemodialysis uses a special filter called a dialyzer to
remove wastes and extra fluid from the blood
160
Hemodialysis: Nursing Care
 Weigh child before/ after hemodialysis
 Check patency of AV fistula/ graft site by palpating thrill, auscultating bruit
 No BP or blood draws on arm with access site
 During hemodialysis:
 Use strict aseptic technique, standard precautions
 Monitor VS, fluid balance, clotting times, blood flow, patency of access site
 After dialysis: monitor VS, access site for bleeding, S/S of disequilibrium
syndrome
 Educate parents:
 Daily care of access site
 S/S complications (infection, bleeding)
 Promote lifelong coping skills
161
Review Question
 A client has an arteriovenous (AV) fistula in place in the right
upper extremity for hemodialysis treatments. When planning
care for this client, which of the following measures should the
nurse implement to promote client safely?
A. Take blood pressures only on the right arm to ensure accuracy
B. Use the fistula for all venipunctures and intravenous infusions
C. Ensure that small clamps are attached to the AV fistula
dressing
D. Assess the fistula for the presence of a bruit and thrill
162
Renal Replacement Therapy:
Kidney Transplantation
 Healthy donor kidney surgically
placed in lower abdomen
 Preferred method of renal
replacement therapy in the pediatric
population
 Blood type compatibility, HLA match;
living relative donor preferred
 Lifelong immunosuppressive therapy
 Complications: opportunistic
infection, lymphomas and skin
cancer, and hypertension
163
• Rejection – major cause of
transplanted kidney loss
o S/S rejection: Fever; ↑ BUN &
creatinine; pain & tenderness;
irritability; weight gain
164164
164
Review Question
 The home care nurse is making follow-up visits to a
pediatric patient following renal transplant. The nurse
assesses the child for which signs of acute graft
rejection?
A. Hypotension, graft tenderness, and anemia
B. Hypertension, oliguria, thirst, and hypothermia
C. Fever, hypertension, graft tenderness, and malaise
D. Fever, vomiting, hypotension, and copious amounts of dilute
urine
165
Kidney Transplantation: Nursing Care
 Teach child/ parents about transplantation process
 Provide emotional support & guidance to the child/ parents
 Prepare the child/ parents for the possibility of continuing to need
hemodialysis temporarily after the transplant because the transplanted
kidney might not work effectively right away
 Administer immunosuppressive medications as ordered
 Monitor for S/S infection; keep child away from anyone with an infection
 Teach child/ parents about follow-up appointments, medications, health
promotion, when to call the physician
 Teach child/ parents about signs of rejection and infection
166
167
Cryptorchidism
Structural Defects of the
Reproductive System
167167
168
Cryptorchidism
 Failure of one or both testes to descend
through inguinal canal; hidden testis
 3-6% term; 20-30% preterm infants
 Testosterone deficiency, an defective
testis, structural problem, early gestational
age
 Complications: infertility, testicular CA
 Usually detected newborn exam
 Goals of treatment:
 Preserve testicular function
 Normal scrotal appearance
168
Bilateral Cryptorchidism
169
Review Question
Why isitimportant that thetestes areinthescrotalsac?
169
Cryptorchidism: Collaborative Care
 Mosttestesspontaneouslydescend
 Hormonetherapy–humanchorionic
gondadotropin (hCG)
 Surgicalprocedure(orchiopexy)iftestes
donotdescendintoscrotalsacby6-12
months
 Riskoftesticularcancerifuntreated
 Monthlytesticularself-examinationis
recommendedforallmalesbeginningin
puberty,butisessentialinmaleswith
historyofundescendedtestis
170
Orchiopexy
171
Review Question
 Thenewbornhasbeendiagnosed withcryptorchidism.The
physicianhasorderedhumanchorionic gonadotropin (hCG)to
beadministered tothebaby.Themotherasksthenursewhythe
babyisreceiving thisdrug.Thenurse’sbestexplanation wouldbe
thedrugwill:
A. Maintainanadequatetemperaturearoundthetestes.
B. Preventinfectionsintheundescendedtestes.
C. Preventthedevelopmentofcancer.
D. Promotedescentofthetestes.
171171
Cryptorchidism: Nursing Care
 Surgical repair: orchiopexy is done between 6-12
months of age
 Postoperatively, keep the surgical area dry for 1-2 days
 Encourage bed rest
 Monitor voiding
 Apply ice to surgical area
 Administer prescribed analgesics (acetaminophen or
ibuprofen)
172
Cryptorchidism: Discharge Instructions
 Incision care:
 Diaper area should be cleaned well with each diaper change
 Sponge baths only for 2 days after surgery
 No medicine/ ointment placed over incision
 Prevent pulling on the thigh suture postoperatively because the testis could
reascend into the abdomen through the inguinal canal if the suture disconnects
 Child should avoid straddling activities or strenuous activity for 2-3 weeks
 Have the child wear loose clothing
 Use analgesics as needed (acetaminophen or ibuprofen)
 Observe for redness, warmth, swelling, purulent discharge, fever,
increased pain at the incision site (indicative of infection)
173
174
Review Question
 Ababyisborn6weeksprematurely.Onadmissiontothe
nursery,thenurseisunabletolocateanytesticlesinthe
scrotum.Thenurseshould:
A. Immediatelynotifythephysicianasthechildisatriskforrenalfailure.
B. Notethefindingsinthechild’srecordandtakenofurtheractionatthis
time.
C. Discusswiththefathertheneedforsurgicalcorrectionofcryptorchidism.
D. Catheterizethechildtodetermineifurineispresentinthebladder.
174174
175
Review Question
 Whentalkingwiththeparentsofachildoradolescentwhohas
ahistoryofcryptorchidism, thenursewillmoststressthe
importanceofthechilddoingwhichofthefollowingthings?
A. Gettingamumpsvaccineboosterevery5years
B. Complying100%withhormonetherapybeginningatage15
C. Wearingatesticularsupport(jockstrap)whileparticipating in
sports
D. Doingmonthlyself-testicular examinations beginning atage13
175
176

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Alterations in genitourinary function in children

  • 1. 11 JoyA.Shepard,PhD,RN-BC,CNE JoyceBuck,PhD(c),MSN,RN-BC,CNE 1 Alterations in Genitourinary Function (Urinary Tract, Renal, and Reproductive Conditions)
  • 2. 2 Learning Outcomes 1. Describeanatomy&physiologyof thegenitourinarysystemandpediatric differences 2. Discussnursingmanagementofchildwithgenitourinarystructuraldefect 3. Developnursingcareplanforchildwithurinarytractinfection 4. Outlineaplantomeetfluidanddietaryrestrictionsofchildwithrenaldisorder 5. Summarizepsychosocialissuesforchildrequiringgenitourinarysurgery 6. Plannursingcareforchildwithacute&chronicrenalfailure 7. Identifygrowth&developmentissuesforchildwithchronicrenalfailure 22
  • 4. 44 4 A nephron holds: The Glomerulus Bowman’s capsule Proximal tubule Loop of Henle Distal tubule Collecting duct The Functional Unit of the Kidneys is the Nephron
  • 5. 5 Review: Anatomy of the Kidney  Outercortex  Composedoftheglomeruliandconvoluted tubules ofthenephronandbloodvessels  Innermedulla  Composedoftherenalpyramid 5
  • 6. Review: Function of the Kidney  Regulates total body water  Regulates blood pressure (renin-angiotensin-aldosterone)  Regulates acid-base status  Regulates electrolytes, calcium and phosphorus  Converts Vitamin D to the active hormone (calcitriol)  Produces Erythropoietin (EPO)  Removes nitrogenous wastes  Drug metabolism and removal 6
  • 7. 7 Review: Anatomy Reproductive System  Pelvic Cavity: contains urinary bladder, and reproductive organs  Malereproductive system  Testes,scrotum,penis,prostate,vasdeferens(drainsintourethra) Testesproducetestosterone(primarymalesexhormone);spermafter puberty  Femalereproductive system  Ovaries,fallopiantubes,uterus,vagina Ovariesproduceestrogen(primaryfemalesexhormone);ovumafterpuberty 7
  • 8. 8 Review: Physiology Genitourinary System  Renal/ Urinary System  Main function – Regulates fluid and electrolyte balance  Filters blood plasma  Returns useful substances to blood  Eliminates waste  Regulates  Osmolarity of body fluids, blood volume, BP  Acid-base / electrolyte balance  Secretes Renin & erythropoietin  Detoxifies free radicals & drugs  Reproductive System  Main function – Provides for perpetuation of the species 88  See Kidney Function Part 1 and Kidney Function Part 2
  • 10. 10 Children are not just small adults…. 1010
  • 11. 1111 11 Development of the Genitourinary System
  • 12. 12 Pediatric Differences – Urinary System 12
  • 13. 13 Fluid & Electrolyte Balance Differences  Incomparisontoadults,childrenareatagreaterriskforfluid&electrolyte imbalance.Childrenhave:  A proportionatelygreateramountofbodywater  Requiremorefluidintakeandsubsequentlyexcretemorefluid  A greaterbodysurfaceareaandahigherpercentageoftotalbodywater  A greaterpotentialforfluidlossviathegastrointestinaltractandskin  Anincreasedincidenceoffever,upperrespiratoryinfections,andgastroenteritis  A greatermetabolicrate  Immaturekidneysthatareinefficientatexcretingwasteproducts  Kidneysthathaveadecreasedabilitytoconcentrateurine  Increasedriskfordevelopinghypernatremiabasedontheirinabilitytoverbalizethirst 13
  • 14. 14 Pediatric Differences: Urinary System  Allnephronspresentatbirth  Renalgrowth  Mostduringfirst5yrs  Fullsizebyadolescence  Renalefficiencyincreasesaschildmatures  Kidneyfunctionisimmatureuntilafter2yearsofage  Glomerularfiltration&absorptionimmature  Infantsmorepronetofluidvolumeexcess&dehydration  Lessefficientregulatingelectrolyte&acid-basebalance 1414
  • 15. 15 Urinary Output  Urinaryoutputperkilogramofbodyweightdecreasesas childagesbecausethekidneysbecomemoreefficient  Infants 2-3mL/kg/hr  Toddler/Preschooler 2mL/kg/hr  SchoolAge 1-2mL/kg/hr  Adolescent 0.5-1mL/kg/hr 1515 1 gram diaper weight = 1 mL of urine
  • 16. 16 Bladder  Bladdercapacityincreaseswithage  15to50mLatbirth  700mLinadolescence  Estimate bladdercapacity(inounces)–add2tochild’sage 1616
  • 17. 17 Pediatric Differences – Reproductive System 17
  • 18. 18 Pediatric Differences: Reproductive System  Infemaleinfants,theexternalgenitaliamaybeprominentdueto maternalestrogen  Labiaminoramayprotrudebeyondlabiamajora  Testiclesmayappearlargeatbirthinproportiontosizeofinfant  Mayfailtomoveintothescrotum,causingundescendedtestes  Theforeskinmaybetightatbirth,causing phimosis  Thesexorgansdonotmatureuntilonsetofpuberty  Secondarysexcharacteristicsoccurwithonsetofpuberty 18
  • 20. 20 Terms Commonly Used to Describe Urinary Dysfunction  Dysuria:Difficultyinurination  Frequency:Abnormalnumberofvoidings inashortperiod  Urgency:Urgetovoidbutinability todoso  Nocturia:Awakening duringthenighttovoid  Enuresis:Uncontrolled voidingafterbladdercontrolhasbeen established (bedwetting)  Polyuria:Increasedurineoutput  Oliguria:Decreased urineoutput 20
  • 21. 21 Focused Health History  Mother’s pregnancy/ child’s birth history  Family history: GU-specific disorders  Review of fluid intake (including type of fluid)  Urinary tract infections, fevers of unknown origin, dysuria  Toilettraininghistory,voidingandbowelhistory,voidinghabits(e.g.,positioningduringvoiding)  Any problems or changes with voiding (e.g., nocturia or enuresis)  Rectum/ genitalia: any rashes, sores, or discharges  Male children: circumcision status, prepuce issues, inguinal bulge/ scrotal swelling, failure of testes to descend  Females (if appropriate):  Menstrual History – menarche, LMP, interval, regularity, duration, amount of flow, dysmenorrhea  Obstetrical History - Gravida, Term, Para, Abortion, Live, Stillbirth (GTPALS)  ****For adolescents, ask about sexual activity with parents out of room**** 21
  • 22. 22 Urinary Symptoms  Enuresis(bedwetting)  Newonsetincontinence  Frequency,urgency,quantity  Dysuriaanditstimingduringvoiding(atbeginningorend,throughout)  Changeincolorandodorofurine  Hematuria  Presenceofstonesorsedimentintheurine  Toilettrainingproblems 22
  • 23. 23 Toilet Training Readiness  Children<2yrsgenerallycannotmaintainbladdercontrol  12months:nocontroloverbladder  18to24months:somechildrenshowsignsofreadiness  Somechildrenmaynotbereadyuntilaround30months  Thepotty-trainingyearsareespeciallyriskyfordevelopingUTI  Remindchildtovoidoftenevenifhe/sheisnothavingaccidents  Remindfemalechildrentowipefromfronttoback  Achildwhoisuncircumcisedshouldbetaughtatpottytraininghowto graduallyandgentlyretracttheprepuceforvoidingandhygiene 2323
  • 24. 2424
  • 25. 25 Review Question  Amotherisinquiringaboutherchild'sabilitytopottytrain. Whichofthefollowingfactorsisthemostimportantaspect oftoilettraining? A. Theageofthechild B. Thechild’sabilitytounderstand instructions. C. Theoverallmentalandphysicalabilities ofthechild. D. Frequentattemptswithpositivereinforcement. 25
  • 26. 26 Anomalies & Diseases: Genitourinary  Congenital/chromosomalanomalies(e.g.,singleumbilical artery,low-setears,eartags);ambiguousgenitalia  Cystitis,pyelonephritis,renaldisease  GUsurgeryorprocedures  Male: Phimosis,cryptorchidism, hydrocele,testiculartorsion 26
  • 27. 27 Single Umbilical Artery Associated with increased incidence of urogenital abnormalities 27
  • 28. 28 Low-Set Ears & Urinary Tract Anomalies 28 Suspect urinary tract/ kidney anomalies
  • 30. 30 Assessment of the Genitourinary System  Review:AssessingtheAbdomenforShape,Bowel Sounds,andUnderlyingOrgans(pp.143-145)  Review:AssessingtheGenitalandPerinealAreasfor ExternalStructuralAbnormalities(pp.145-149) 30 See video “Pediatric Assessment” 24:07 – 25:47 See video “Physical Exam & Health Assessment: Child” 17:08 – 18:49
  • 32. 32 Nursing Diagnoses  UrinaryIncontinence  ImpairedUrinaryElimination  UrinaryRetention  ExcessFluidVolume  RiskforDeficientFluidVolume  RiskforImbalanced FluidVolume  RiskforElectrolyteImbalance  Toileting Self-CareDeficit 3232
  • 33. 33 GU Process Focus  Dailymonitoringofintake/outputandweightarevitalinassessingalterationsinfluid- electrolytebalanceinthepediatricpatient  Assessvitalsigns,notingthatbloodpressureisoftenelevatedwithglomerulonephritis andnephroticsyndrome  Monitorserumelectrolytes,creatinine,andBUNlevels(arisingcreatinineandBUN suggestspoorrenalfunctioning)  Measureheight,weight,andbodymassindex(failuretothrivecanbeassociated withurinarytractinfectionsininfancyandincreasedweightcanbeassociatedwith nephroticsyndrome)  Noteearpositionandformation(low-setorabnormalearsmaybeanindicationof congenitalrenalconditions) 33
  • 35. 35 Laboratory Tests  Urinalysis  Urineculture  Bloodureanitrogen(BUN)  Serumcreatinine  Creatinineclearancetest/glomerularfiltrationrate(GFR)  Urinealbumin(proteinuria)  Urineproteintocreatinineratio  Basicmetabolicpanel/CBC  Serumalbumin 35
  • 36. 36 Urinalysis (UA)/ Urine Culture  Specificgravity:1.001 – 1.035  pH: 4.6 – 8.0  Urinecolor  Appearance  Leukocyteesterace  Protein  Glucose  Ketones  Occultblood  Bilirubin  Urobilinogen  Nitrite 3636 Which of these components (if positive) would indicate a urinary tract infection?
  • 37. 37 Urine Specific Gravity  Reliable assessmentofpatient’s hydrationstatus  1.001–1.035 Normalvalue IncreasedUrineSG Dehydration–diarrhea–excessivesweating-vomiting DecreasedUrineSG Excessivefluidintake–pyelonephritis-glomerulonephritis 3737
  • 38. 38 Urine Collection 38 Application of urine collection bag 38 See Videos: Urine Samples Collection Pediatric Urine Specimen Collection of Infant
  • 39. 39 Review Question  Whichofthefollowinginterventionswillhelpobtainaccurate urinalysisdata? A. Forcefluidsto1000mLpriortospecimencollection. B. Cleansethespecimencontainerwithpovidone-iodine(Betadine)prior tocollectingthespecimen. C. Allowtheurinetocooltoroomtemperaturebeforetakingittothelab. D. Provideclient/parenteducationforspecimencollectionbeforethe specimenisobtained. 3939
  • 40. 40 Diagnostic Tests (p. 766)  ComputedTomography(CT)  Cystoscopy  FunctionalRadionucleotideRenalScan  IVP–IntravenousPyelogram  RenalBiopsy  RenalorBladderUltrasound  VCUG–VoidingCystourethrogram 4040
  • 41. 41 Computerized Tomography (CT Scan) 4141 Abdomen CT Scan
  • 43. 43 Functional Radionucleotide Renal Scan  Evaluates function of entire urinary system, from kidneys through bladder  Nuclear medical imaging  Requires use of a radiopharmaceutical tracer through an IV catheter  Gamma camera takes images (scintigraphy) 43
  • 45. 45 Intravenous Pyelogram (IVP) 45 Kidney function analyzed Watch for allergic reaction to dye Dye can be toxic to kidneys Push fluids Monitor I & O 45
  • 46. 46 Review Question  Achildreturningtotheunitafteranintravenouspyelogram(IVP) hasanordertodrinkextrafluids.Whenthemotherasksthe purposeofthesefluids,thenurserespondsthatincreasedfluid intakewill: A. Overhydratethechild. B. Increaseserumcreatinine levels. C. Make-upforfluidlossesfromNPOstatusbeforetests. D. Flushanyremaining dyefromtheurinarytract. 4646
  • 50. 50 Treatment Modalities  Urinarydiversion Stents Drainagetubes  Intermittent catheterization Watchforlatexallergies  Pharmacologicalmanagement Antibiotics Anticholinergicforbladderspasm(oxybutynin[DitropanXL]) 5050
  • 52. 52 Urinary Tract Infection (UTI)  Infection in urinary system (urethra, bladder, ureters, or kidneys)  Cystitis: Lower UTI; urethra or bladder  Pyelonephritis: Upper UTI; ureters, renal pelvis, or kidneys  Usually of bacterial origin (e coli); characterized by inflammation  Common in childhood; highest frequency ≤ 2 yrs of age  Uncircumcised males: 10-fold incidence  Prompt diagnosis/ treatment essential  See video Urinary Tract Infection 5252  The male and female urinary tracts are similar except for length of urethra
  • 53. 53 UTI: Etiology/ Pathophysiology  Urethralexposuretoorganismsortrauma  Most commoncausativeorganism:Escherichiacoli  Occursmorefrequentlyingirlsbecausethe short urethraislocatedcloseto anus  Pathogensenterasanascendinginfection  Teenager:sexualintercourseduetofrictiontrauma  Urinarystasis  Anatomicabnormalities;scarring/strictures  Hydronephrosis;hypospadias,epispadias  Neurogenicbladder–incompleteemptyingofbladder  Intheolderchild:infrequentvoidingandincompleteemptyingofbladderorconstipation  Vesicoureteralreflux(VUR)  Urineflowsbackwardsintouretersandkidneys;providesmediumforbacteriatogrow 5353
  • 54. 54 Review Question Which of the following organisms is the most common cause of UTI in children? A. Staphylococcus B. Klebsiella C. Pseudomonas D. Escherichiacoli 54
  • 55. 55 UTI - Females  More common (generally) in females  Short urethra  Improper wiping  Bubble baths  Nylon under pants  Current guidelines – renal and bladder ultrasound with first febrile UTI followed by VCUG if indicated  Second febrile UTI – VCUG 5555
  • 56. 56 UTI – Males  UTIs in males tend to be complicated  More common in males than females during 1st 3 months of life  Males 2-24 months:  Febrile with first UTI  Renal & bladder ultrasound – hydronephrosis, scarring, obstructions, masses  2nd episode febrile UTI  VCUG – vesicoureteral reflux  Higher incidence of UTIs in uncircumcised males 5656
  • 57. 57 Uncircumcised Males  Instructparentstogentlyretractforeskinforcleansing  Donotforcetheforeskin  Donotleaveforeskinretractedoritmayactastourniquet and obstructtheheadofthepenisresultinginemergency circumcision 5757
  • 58. 58 UTI: Diagnostic Tests  Urine for culture and sensitivity  Clean catch  Catheterization  Suprapubic aspiration  A Positive Test  Bacteria colony ≥ 50,000 per mL  Positive leukocyte esterace; positive nitrite tests; white blood cell (WBC) casts  Ultrasound: structural abnormalities, scarring  Voiding cystourethrogram (VCUG): vesicoureteral reflux 58
  • 59. 59 UTI: Clinical Manifestations  Signs & symptoms not always clear (atypical presentation)  Typical S & S of older children and adults – dysuria, frequency, urgency, burning, hematuria – may not be present  Newborn/ infant: unexplained fever; failure to thrive; poor feeding; vomiting; diarrhea; foul-smelling urine; irritability; lethargy  Fever of unknown origin (child ≤ 2 yrs): test for UTI  Toilet-trained child: new onset incontinence, wetting accidents  Upper UTI S & S: high fever, chills, abdominal pain, flank pain, costovertebral-angle tenderness, vomiting, malaise (i.e., vague feeling of general discomfort) 5959 See “Clinical Manifestations Urinary Tract Infection” – p. 768
  • 60. 60 Review Question UTI: What are the differences between older child/ adult S & S and infant-child S & S 60
  • 61. 61 UTI: Collaborative Care  Obtainurinespecimen(orbloodcultures)beforeantibiotics!  ComplicatedUTI/pyelonephritis:hospitalization,IVfluids,parenteralantibiotics  UncomplicatedUTI:oralantibiotictherapyfor10to14days  Escherichiacoli,Enterococcus,Proteus,&Klebsiellamostcommonorganisms  Amoxicillin/clavulanic(Augmentin),sulfamethoxazole/trimethoprim(Bactrim,Sulfa), cephalexin(Keflex),cefixime(Suprax)  Increasefluidintake  Acetaminophen/ibuprofenforpain  Repeaturinalysis–usuallyafter72hrsoftxtomakesuretxiseffective 6161 See “Prevention of Urinary Tract Infections” – p. 769
  • 62. 62 UTI: Nursing Education  Antibiotics–takefullcourse  Changediaperfrequently  Teachgirlstowipefronttoback  Encouragechildrentodrinkperiodicallyduringtheday  Nobubblebaths  Encouragefrequentvoiding  Discourage“holding”urine  Usecottonunderwear  Menstruatinggirl– changepadevery4hours  Whengirlsbecomesexuallyactive– urinateimmediatelyafterintercourse 6262
  • 63. 63
  • 64. 64 Review Question  Themostimportant nursingactivity inmanagingayoung child diagnosed withurinarytract infection (UTI)isto: A. Provideadequate nutrition toprevent dehydration. B. Prevent enuresis. C. Administer ordered antibiotics onschedule. D. Restrictfluidsto provide kidneyrest. 6464
  • 65. 65 Review Question  Theparentsofachilddiagnosedwithupperurinarytract infection(UTI)askthenursewhythechildneedsadaily weight.Informulatingaresponse,thenurseincludesthatit isimportantbecauseadailyweightwill: A. Determineifthechild’scaloricintakeisadequate. B. Indicatetheneedfordietaryrestrictionsofsodiumandpotassium. C. Keeptrackofpossiblelossorgainoffluidretainedinbodytissues. D. Tracktheamountoffluidingestedorallyeachday. 6565
  • 66. 66 Bladder Exstrophy Hypospadias & Epispadias Obstructive Uropathy Vesicoureteral Reflux Structural Defects of the Urinary System (usually hereditary) 6666
  • 67. 67 Bladder Exstrophy  Exstrophy: turning inside out  1 in 40,000 births  Twice as common in males  Congenital malformation in which the abdominal and anterior bladder walls do not fuse during fetal development 6767 •Inside-outbladder; •Mucosa(inside lining)ofbladder exposed
  • 68. 68 Bladder Exstrophy: Clinical Manifestations  Visible defect revealing bladder mucosa/ ureteral orifices through open abdominal wall  Constant drainage of urine; excoriated skin  Mass bright red tissue (bladder)  Numerous additional congenital anomalies: epispadias, short penis, upward chordee, split clitoris, forward-positioned anus, low umbilicus, wide pelvis, waddling gait 6868
  • 69. 69 Bladder Exstrophy: Collaborative Care  Multidisciplinary approach  Surgery within 48 hrs after birth to close the skin over bladder and reconstruct male urethra/ penis  Urethral stents/ suprapubic catheter to divert urine  Further reconstructive surgery between 6 mos to 5 yrs of age  Requires lifelong follow-up 6969
  • 70. 70 Before and After Surgical Repair 70 Details: http://www.pediatricurologybook.com/bladder_exstrophy.html
  • 71. 71 Goals of Treatment  Closebladder/abdominalwall  Preserverenalfunction  Attainurinarycontrol  Acceptableappearance/ functionofgenitals  Sexualfunction  Typical&normalchildhood 7171
  • 72. 72 Nursing Care  Pre-Op:Preventinfectionandtrauma  Umbilicalcordtiedwith2.0silksuture(notumbilicalcordclamp)  Bladdercoveredwithsterileplasticwrap;irrigatedwithwarmsaline  Skinprotectedwithointmentorsealant  Infantpositionedsupinewithdiaperunderneath  Post-Op:  Maintainproperalignment(noabduction);monitorperipheralcirculation;provide meticulouswound/skincare  Monitorrenalfunction;strictI&O;observeforsignsofobstruction;promotecomfort; administerantibiotics  Supportparents;promotebonding;guidance&dischargeteaching 72 ModifiedBryant’straction
  • 73. 73 Review Question Whichofthefollowing positions would best facilitate healing fortheinfant after bladder exstrophy repair? A. Supine,legssuspendedverticallywithlegsclosetogether B. Leftside-lyingposition C. Rightside-lyingposition D. Low-Fowler’s,legsbentatkneeswithwedgebetweenlegs 73
  • 74. 74 Long Term Complications  Urinaryincontinence  Infection  Bodyimage  Inadequatesexualfunction 7474
  • 75. 75 Hypospadias & Epispadias 75 Hypospadias EpispadiasEpispadias Hypospadias Recurrent UTIs are a complication of both conditions  Hypospadias: Abnormal opening of urethra on underside of penis rather than tip  Common congenital anomaly of penis  Ranges from mild to severe  Undescended testes may be present  Downward curvature of penis (chordee)  Might interfere with fertility  Epispadias: Abnormal opening of urethra above tip of penis or between clitoris and labia (girls)  Rare congenital anomaly (girls & boys)  Milder expression of bladder exstrophy  Short broad penis, upward curvature  Abnormal clitoris, labia, wide pelvis (girls)
  • 76. 7676 76 Hypospadias  Ventral surface  Below glans penis Epispadias  Dorsal surface  Above glans penis Hypospadias & Epispadias
  • 77. 77 Hypospadias & Epispadias: Collaborative Care  Diagnosis: PrenatalUS,examination atbirth  Circumcisionnotrecommended(foreskinmaybeneededfor reconstructive surgery)  Notreatment necessaryinmilddisorder  Hypospadiasrepair:4-18mos(earlyintervention preferred)  Epispadiasrepair:12-18mos(allowsbladdertimetoenlarge)  Post-op:Forcefluids,keepurinarystentpatent,leavebandagein place,notubbathing untilstentisremoved 7777 See “Caring for the Child After Hypospadias and Epispadias Repair” – p. 772
  • 78. 78 Review Question  Shortlyafterbirth,thenewbornwasfoundtohaveepispadias.Priorto delivery,themotherhadsignedpermissionforacircumcision.The obstetricianisplanningtoperformthecircumcisionimmediatelyafter delivery.Thenurseexplainstothemotherthatthecircumcisionwillnot bedoneatthistimebecause: A. Themothershouldnothavesignedconsentbeforedelivery. B. Thefatheralsoneedstosignpermissionforsurgery. C. Theprepucewillbeusedforthesurgicalcorrection. D. Theriskofinfectionisgreaterwithachildwithepispadias. 7878
  • 79. 79 Hypospadias & Epispadias: Nursing Care  Keeptheareacleantopreventinfection  Assessforpostsurgicalcomplications  Monitorforsignsofinfection  WatchforevidenceofUTI  Assesspain(oxybutyninrelievesbladderspasms)  Encouragetheparentstoexpresstheirfeelings/concernsandprovide emotionalsupport  Dischargeinstructions: Bandagedressingcare,careofstent,activity restrictions,nutrition,paincontrol,andsigns/symptomsofcomplications 79 See “Caring for the Child After Hypospadias and Epispadias Repair” – p. 772
  • 80. 80 Review Question  Aninfanthasbeenadmittedfortreatmentofhypospadias. Nursingmanagement ofthechildandfamilyincludes: A. Parenteducation regarding steroidtherapy. B. Addressingparentalanxietyrelatedtofunctioning and appearanceofthepenis. C. Homehealthteaching ofproperstraightcatheterization techniques. D. Monitoring forsignsandsymptomsofnephroticsyndrome. 8080
  • 81. 81 Double-Diapering Technique After Surgery for Hypospadias/Epispadias Repair 81
  • 82. 82 Review Question  Themotherofaninfantwhounderwentsurgerytorepair hypospadiasasksthenursewhytheinfantisdouble- diapered.Thenursewouldrespondthatthismethodof diapering: A. Protectstheurinarystentthathasbeenputinplace. B. Adequatelymeasurestheurinaryoutput. C. Providesformaximumabsorptionofurine. D. Providesoptimalprotectionofperinealskinfrominfectedurine. 8282
  • 83. 83 Hydronephrosis/ Hydroureter (Obstructive Uropathy)  “Water on kidney” enlarges renal pelvis, damages nephrons  Mechanical blockage/ obstruction in urinary tract; most often unilateral  Congenital malformations: ureters, ureteral valves, bladder, urethra  Can lead to: nephron destruction, HTN, ↓ ability to conserve Na+, metabolic acidosis, recurrent UTIs, progressive irreversible renal failure  Goal: maintain integrity of kidney until normal urinary flow established  Early diagnosis essential (US) 8383
  • 84. 84 Common Sites of Obstruction in Upper/ Lower Urinary Tract (Congenital Malformations) 84 84  Why would damage from the posterior urethral valves be potentially worse than other obstructions?
  • 85. 85 Review Question  Aparentasksthenursewhatwilleventuallyhappeniftheinfant doesnothavehiscongenital hydronephrosistreated.Themost accurateanswerbythenursewillbewhichofthefollowing? A. “Ifthehydronephrosisisnottreated,thechildcandevelopbladdercancer.” B. “Theinfantcanbecomedangerouslyhypotensivebecauseoftheobstructionto urineflow.” C. “Smallcalciumstonescanoccurasaresultofuntreatedhydronephrosis, causingfurtherobstruction.” D. “Untreatedhydronephrosiscanleadtoirreversiblekidneydamageand eventualkidneyfailure.” 85
  • 86. 86 Hydronephrosis: Clinical Manifestations  Distended bladder/abdomen  HistoryofUTI:flankpain,feverandchills  S&Srenalinsufficiency: decreaseinurinaryoutflow,swelling, hypertension, anemia,poorappetite; decreasedabilityofkidney toconservesodiumandconcentratetheurine  NeonatemaypresentasUTI  Outerearabnormalities, singleumbilical artery  Anolderchildmaybeasymptomatic exceptforFTT 8686
  • 87. 87 Review Question  Anurseisreviewingapatient’schartandnoticesthatthechild suffersfromhydronephrosis. Whichofthefollowing wouldthe nurseexpecttoseewiththispatient?  A.Swollenkidneyduetourinenotdraining fromkidney  B.Dehydrationfromspittingupandseveralloosestools  C.Profuseurinationandurinaryfrequency  D.Spinalcorddefectcausinginability toemptybladder 87
  • 88. 88 Hydronephrosis: Diagnostics  Ultrasound of kidneys/bladder  VCUG: voiding cystourethrogram  Diuretic renography with radioisotope  Requires use of a radiopharmaceutical tracer & intravenous furosemide through IV 8888
  • 89. 89 Hydronephrosis: Collaborative Care  Goalsofcorrection:Preserverenalfunction,lowerpressurewithin collectionsystem  Temporaryurinarydiversionmaybeneededtorelievethepressure  Surgicaltreatment:insertionofureteralstents,nephrostomy tube; pyeloplasty; valverepair/reconstruction  Nephrectomy ifrenaldamageisnotreversible  Nursingcare:support/educateparents;monitorVS,I&O; observeforsignsofurinaryretention; administermedications 8989
  • 90. 90 Vesicoureteral Reflux (VUR)  Regurgitation of urine from the bladder into the ureters due to faulty valve mechanism at the ureterovesicular junction  Predisposes child to: UTIs; pyelonephritis; hydronephrosis  White children, girls, children ≤ age 2; tends to run in families  Assessment findings: same as for UTIs/ FTT  Diagnostic tests: kidney/ bladder US, VCUG, nuclear scan  Goals: prevent pyelonephritis, renal scarring, chronic renal failure  Tx: Long-term daily low-dose antibiotic prophylaxis; valve repair or reconstruction; endoscopic surgery; surgery to re-implant ureters 9090
  • 92. 92 Vesicoureteral Reflux: Nursing Care  Assist with preoperative studies as needed  Provide postoperative care:  Observe for signs of infection  Monitor VS, I & O  Monitor drains; may have one from bladder and one from each ureter (ureteral stents)  Check output from all drains (expect bloody drainage initially) and record carefully  Observe drainage from abdominal dressing; note color, amount, frequency  Administer medication for bladder spasms as ordered  Support/ educate parents
  • 93. 93 Nephrotic Syndrome Acute Poststreptococcal Glomerulonephritis RenalFailure RenalReplacement Therapy Renal Disorders: Acute, Chronic, & Structural Causes 9393
  • 94. Nephrotic Syndrome/ Nephrosis (Minimal Change Nephrotic Syndrome) 94  Clinical state characterized by massive proteinuria, edema, hyperlipidemia, and hypoalbuminemia  Alterations in the glomerular membrane allow proteins, especially albumin, to pass in urine resulting in decreased serum osmotic pressure contributing to edema  Most common presentation of glomerular injury in children  Constellation of clinical findings, not a disease (all a result of massive renal losses of protein)  Most common form: Minimal Change Nephrotic Syndrome (MCNS); accounts for 85% of all pediatric cases  Peak incidence 2-6 years old; twice as frequent in boys  Etiology unknown; autoimmune process suspected  See video Nephrosis (Nephrotic Syndrome)
  • 95. 95
  • 96. Review Question 96 Nephrotic syndrome is caused by damage to which part of the nephron????? MinimalChangeNephroticSyndrome/ Effacement of foot processes
  • 97. 97 Contrast Between Normal Glomerular Anatomy & Changes of Nephrotic Syndrome (p. 818) 97 Massiveamountsofproteinare excretedinurine Edemaresultsfromdecreased oncoticplasmapressure,renin- angiotensin-aldosteroneactivation,& antidiuretichormonesecretion Loweralbuminbloodlevel stimulatesthelivertogeneratelipids &excessiveclottingfactors Loss of podocyte foot processes = MASSIVE PROTEINURIA
  • 98. MCNS: Clinical Manifestations  Pitting edema (around the eyes, scrotum, abdominal ascites, dependent areas, lower extremities)  Weight gain over a short period (from fluid retention)  Pale, poor appetite, irritability, fatigue, abdominal discomfort, vomiting, diarrhea  Pulmonary edema, effusions  Malnutrition, growth failure  Foamy appearance of urine  Normal or slightly elevated BP 98 Periorbital, scrotal edema
  • 99. Nephrotic Syndrome: Anasarca 99 Describe the fluid shifts in Anasarca…. What sorts of health complications do you anticipate?
  • 100. 100 MCNS: Diagnostic Evaluation  Proteinuria (First morning urine sample)  Urine protein/ creatinine ratio > 2  Hypoproteinemia  Serum albumin < 2.5 g/dL  Hyperlipidemia/ Lipiduria  ↑ Cholesterol, triglycerides; lipids in the urine  Hypercoagulability (PT/PTT/INR/ antithrombin III)  Basic metabolic panel (BMP)  BUN/ Creatinine normal unless renal damage  Hyponatremia (low serum sodium)  Kidney biopsy 100100 Monitor serum albumin and electrolytes, particularly potassium and sodium.
  • 101. Review Question Which of the following signs and symptoms are characteristic of Minimal Change Nephrotic Syndrome? A. Gross hematuria, proteinuria, fever B. Hypertension, edema, fatigue C. Poor appetite, proteinuria, edema D. Body image change, hypotension 101
  • 102. 102 MCNS: Collaborative Care  Goals of treatment: minimize edema; decrease urinary protein loss; prevent infection; & prevent toxic medication side effects  Trial of corticosteroids: 1st step in treatment  Oral prednisone minimum of 6 months  If responsive, urine protein levels fall  Relapse/ remission not obtained: immunosuppressive agents  Diuretic therapy  Intravenous albumin followed by furosemide  Metolazone 30 minutes before furosemide (for resistant edema)  Antihypertensive therapy: ACE – to help reduce proteinuria  Balanced nutrition, low-salt diet  Prevent or treat any infection 102
  • 103. MCNS: Nursing Care  Nursing goals: manage symptoms; prevent complications; meet nutritional needs; address emotional needs of child/ family  Provide rest, cluster care  Monitor I&O, specific gravity, proteinuria  Daily weights on same scale and amount of clothing  Monitor edema and measure abdominal girth  Promote pulmonary health through position changes, activity as tolerated, deep breathing & coughing exercises, spirometer use 103
  • 104. MCNS: Nursing Care 104  Monitor VS, especially temperature for signs of infection  Encourage small, frequent meals within restriction guidelines o Salt & fluids may be restricted during edematous stage  Prevent skin breakdown & pressure sores; turn frequently  Administer medications as ordered; carefully monitor side effects  Prevent infection: meticulous hand hygiene, vaccinations, prevent contact with infectious persons
  • 105. Review Question  A nurse is assigned to care for a client with nephrotic syndrome. The nurse assesses which important parameter on a daily basis? A. Weight B. Albumin levels C. Activity tolerance D. Blood urea nitrogen (BUN) level 105
  • 106. Corticosteroids: Side Effects 106  Immunodeficiency  Hirsutism  Moonfacewithruddycheeks  Acne  Dorsocervicalfatpads  Ecchymosis(easybruising)  Truncalobesity  Moodswings–inability tosleep 106106
  • 107. 107 Moon Face 107 High-dose corticosteroid therapy produces a characteristic “moon face” appearance 107
  • 109. 109 Review Question While a child is receiving prednisone (Orapred) for treatment of nephrotic syndrome, it is important for the nurse to assess the child for: A. Infection. B. Urinaryretention. C. Easybruising. D. Hypoglycemia. 109109
  • 110. 110 Review Question  Achildhasrecurrentnephroticsyndrome.Themotherreportstothe nursethatsheisoverwhelmedwiththecareofherchild.Afterthenurse discussesoptionswiththemother,whichstatementbythemother indicatescontinuedcopingdifficulties? A. “Ijoinedasupportgrouplikeyousuggested.Ihopeitdoessomegood.” B. “I’mgoingtoaskmymother-in-lawtocomeonaregularbasistoallowme anafternoonout.” C. “Myhusbandhasagreedtohelpmemanagemyson’smedication.” D. “We’regoingtoskiphisdietaryrestrictionsonedayaweektoallowusboth somerelaxation.” 110110
  • 111. Acute Poststreptococcal Glomerulonephritis 111  Glomerulonephritis = inflammation of the glomerulus  Autoimmune immune-complex disorder occurring 10-21 days after group A beta-hemolytic streptococcal infection (upper respiratory, pharyngitis, tonsillitis, impetigo)  Children ages 2-6 yrs; more common in boys than girls  Sudden appearance of hematuria,proteinuria, red blood cell casts in the urine, edema, and hypertension with or without oliguria  Immune complexes from recent strep infection become entrapped in glomerular membrane; immune activity targeted at the glomerulus  Inflammation, tissue injury, and obstruction of glomerular capillaries  Reduced glomerular filtration rate (↓GFR)  Sodium and water retained: edema and hypertension
  • 112. Group A Streptococcal Infection Manifestations 112
  • 113. Review Question  A client has been admitted to the hospital with a diagnosis of acute glomerulonephritis. During history- taking the nurse first asks the client about a recent history of: A. Bleeding ulcer B. Deep vein thrombosis C. Myocardial infarction D. Streptococcal infection 113
  • 114. 114 Infection from group A beta-hemolytic Streptococcus leads to an immune response that causes inflammation and damage to glomeruli 114 Protein&redblood cellsareallowedtopass throughglomeruli Bloodflowtoglomeruli isreduceddueto obstructionwithdamaged cells Renalinsufficiency results,leadingto retentionofsodium, water,&waste IMMUNE ACTIVITY targeted at GLOMERULUS Vessels clogged with cells
  • 115. Glomerular Capillaries Clogged With Cells 115  Immune complexes (mixtures of antibodies and antigens) are filtered out of the bloodstream and become trapped within the glomeruli  Body responds by activating its immune defenses, resulting in further damage to the glomeruli
  • 116. 116 Acute Poststreptococcal Glomerulonephritis: Clinical Manifestations  Gross hematuria/ RBC casts  ↓GFR  Oliguria  Azotemia (elevated nitrogenous wastes in blood)  Hypertension  Periorbital edema  Brown foamy frothy urine  Mild/moderate proteinuria 116116 Tea- or cola-colored urine The most common clinical sign of glomerulonephritis is blood in the urine
  • 118. 118  Dx: streptozyme test; ↓ H & H; ↑ BUN, creatinine; hematuria, proteinuria, RBC casts; ↑ erythrocyte sedimentation rate  Tx goals: relief of symptoms, supportive therapy  Monitor urinary output, daily weights, blood pressure, & serum electrolytes  Limited activity, bed rest  Diuretics such as furosemide (Lasix) to reduce fluid overload  Antihypertensive drugs to treat increased blood pressure  Antibiotics (penicillin) if a streptococcal infection is documented or detected  Restriction of fluids to replace insensible losses  Low-sodium, low protein diet (during acute phase) 118118 Acute Poststreptococcal Glomerulonephritis: Collaborative Care
  • 119.  Nursing care: monitor fluid status, prevent infection, prevent skin breakdown, meet nutritional needs, and provide emotional support to the child/ family  Monitor: VS, I & O, daily weight; abdominal girth; watch for signs of renal failure, including decreased (less than 1 mg/kg/hour), or no urine output  Monitor: signs of infection, including fever, malaise, & elevated WBC  Enforce activity limitations, bed rest during acute phase; cluster care  Institute sodium restrictions for the child with hypertension or edema  Educate parents: dietary restrictions (sodium, potassium, & fluid intake)  Administer diuretics/ antihypertensive medications as needed  Provide emotional support 119 Acute PoststreptococcalGlomerulonephritis: Nursing Care
  • 120. 120 Review Question When reviewingaurinalysisreport ofaclientwithacute glomerulonephritis, the nurse wouldexpecttonote: A. Decreased creatinine clearance. B. Decreased specificgravity. C. Hematuria. D. Decreased erythrocyte sedimentation rate(ESR). 120120
  • 121. 121 Acute Renal Failure/ Acute Kidney Injury  Life-threateningdisorder  Kidneysunableto  Clearwastes  Regulatefluidvolume,sodiumbalance, &acid-basehomeostasis  Pre-renal,resultingfromimpairedbloodflow tooroxygenationofthekidneys  Renal,resultingfrominjurytoormalformation ofkidneytissues  Post-renal,resultingfromobstructionof urinaryflowbetweenkidney &meatus  Seevideo3MinuteAcuteRenalFailureforNursingStudents 121121 Suddenlossofrenalfunction
  • 122. 122
  • 123. 123 Review Question Thenurseadmits children withthe following diseases to theunit.Which disease places the childatriskforthe development ofacuterenal failure (ARF)? A. Leukemia. B. Cryptorchidism. C. Nephroticsyndrome. D. Phenylketonuria. 123123
  • 124. 124 The initial kidney injury is usually associated with an acute condition such as sepsis, trauma, and hypotension, or is result of treatment for an acute condition with nephrotoxic medication 124 Injurytothekidneycan occurbecauseofglomerular injury,vasoconstrictionof capillaries,ortubularinjury Allconsequencesof injuryleadtodecreased glomerularfiltration& oliguria Acute Renal Failure/ Acute Kidney Injury
  • 125. 125 Review Question Achild has been admitted in renal failure.The nurse would expect to find: A. Decreased BUN. B. Adequate glomerular filtration. C. Azotemia and oliguria. D. Polyuria and elevated creatinine clearance. 125125
  • 126. Newborn Causes Childhood Causes  Congenital anomalies  Hypotension  Complication ofopenheart surgery  Dehydration  Glomerulornephritis / NephroticSyndrome  Nephro-toxicity /drugtoxicity Acute Renal Failure 126
  • 127. 127 Review Question  Achildisadmitted tothenursingunitwithacuterenalfailure (ARF).Whenreviewingthenursinghistory,thenursenotesa historyofallofthefollowing medicalconditions. Whichismost likelytohaveprecipitated theonsetofARF? A. Chickenpox. B. Influenza. C. Dehydration. D. Hypervolemia. 127127
  • 128. 128 Acute Renal Failure: Clinical Manifestations  Suddenonset  Oliguria  Urineoutputlessthan0.5to1mL/kg/hour  Darkurine  Volumeoverloadduetoretainedfluid  Hypertension,edema,shortnessofbreath  ElectrolyteImbalances–seechart,p.827  Acidosis  Nonspecificsymptoms:nausea,vomiting,lethargy 128 See “Clinical Manifestations” – p. 783
  • 129. 129 Diagnostic Tests  Basic Metabolic Panel (BMP)  BUN and Creatinine elevated  Serum Potassium elevated  Decreased CO2  CBC  Decreased RBCs, H & H due to deficient erythropoietin  ABG  Decreased pH  Decreased Bicarbonate (HCO3−)  GFR (glomerular filtration rate) decreased – most sensitive indicator of glomerular function 129129
  • 131. The Most Deadly Electrolyte Imbalance… 131
  • 132. Review Question  The child with acute renal failure has a serum potassium of 6.0 mEq/L. The nurse would plan which of the following as a priority action? A. Check the sodium level B. Place the child on a cardiac monitor C. Encourage increased vegetables in the diet D. Allow an extra 250 mL of fluid intake to dilute the electrolyte concentration 132
  • 133. 133
  • 134. 134 Review Question The priority concern for the nurse in assessing a child with acute renal failure (ARF) should be to look for which electrolyte imbalance? A. Potassium. B. Sodium. C. Calcium. D. Phosphorous. 134134
  • 135. 135 Urea or BUN Urea is normally freely filtered throughthe renal glomeruli, with a small amount reabsorbedin the tubules andthe remainder excreted in the urine Decrease or increaseinthe valuedoes nottell the cause: pre-renal, post-renal or renal Elevated BUN just tells youthe urea isnot being excreted by the kidney, not why 135135
  • 136. 136 Creatinine Creatinine is a very specific indicator of renal function If kidney function is decreased / creatinine level will be increased Conditions that increase levels: glomerulonephritis, pyelonephritis or urinary blockage 136136
  • 137. 137 Creatinine Levels Adult female: 0.5-1.1 mg/dL Adult male: 0.6-1.2 mg/dL Adolescent: 0.5-1.0 mg/dL Child: 0.3-0.7 mg/dL Infant: 0.2-0.4 mg/dL Newborn: 0.3-1.2 mg/dL. 137137
  • 138. 138 Acute Renal Failure: Collaborative care  Treatmentdependsontheunderlyingcause  Preventpermanentrenaldamage  Reducesymptoms  Supportivecareuntilrenalfunctionreturns  Medications– seechart,p.827  Avoidnephrotoxicmedications(NSAIDs.,radiocontrastagents, aminoglycosideabx)  Dietaryrestrictions–seeTable26-5,p.831  Dialysisifindicated  Seevideo4NursingInterventionsforAcuteRenalFailurePart1andPart2 138138
  • 139. 139 Acute Renal Failure: Nursing Care  Provideemotional supportforchildandfamily  MonitorVS,I&O,dailyweights,serumelectrolytes  Administermedications asordered  Monitornutritional intake–sodium,potassium,andphosphorus mayneedtoberestricted  Meetfluid,electrolyte,andnutritional needs  Preventinfections andcomplications  Dischargeplanning &homecareteaching 139
  • 140. 140140
  • 141. 141 Review Question Afour-year-old childhasbeen diagnosed withrenal failure.Thenurse would ensure thatthedietforthischild wouldcontain: A. Foodshighinpotassiumandsodium. B. Adequatecaloriestooptimizegrowth. C. Foodshighincalciumcontenttopromotebonegrowth. D. Increasedfluidintaketoflushtheurinarysystem. 141141
  • 142. 142 Review Question Ateenager inacuterenal failure has anorderforfluid restriction. What assessment criteriawouldindicate that insufficient fluids arebeing administered tothischild? A. Increasedweightwithdecreasedserumpotassiumlevels. B. Proteinuria. C. Hypernatremiawithweightloss. D. Decreasedpulse. 142142
  • 143. 143 Chronic Renal Failure  Progressive,irreversibledeteriorationofrenalfunction, usually overaperiodofmonthsoryears  Fivestages:ESRDfinalstage  Etiology:congenitalanomalies, hereditary diseases, infections,glomerulonephritis  Signsandsymptoms  Lethargy,fatigue,anorexia,nausea,vomiting,hypertension,growthretardation,edema,volume overload,hyperkalemia,metabolicacidosis,anemia,bonedisease(renalosteodystrophy), cardiovasculardisease,centralnervoussystem abnormalities, delayedsexualmaturation  Seevideo4StagesofChronicRenalFailure&ESRD 143
  • 144. 144 Effects of Chronic Renal Failure  Growthdelays Duetoanemia,metabolismdisturbances,decreasedcaloricintake, metabolicacidosis  Cognitivedelays Duetodecreasedalertness,fatigue,poorschoolattendance  Socialdevelopmentimpairment Duetoalterationofbodyimage,delayedonsetofpuberty,sideeffects ofmedications 144144
  • 145. Chronic Real Failure: Collaborative Care  Dx:BUN/serumcreatinine(mostimportanttests);serumelectrolytes, bicarbonate;CBC;urinalysis(proteinuria,hematuria,pyuria,sp.gravity,hyaline casts);estimationofGFR;US/radionuclidestudies;renalbiopsy  Treatmentdependsoncourseofthedisease  Medications -seechart,p.830  Diettherapy–limit potassium,phosphorus,sodium(seeTable26-5,p.831)  Proteinrestrictedonlytotherecommendeddailyallowanceforchildren  Preventionandtreatmentofcomplicationsofdecreasedkidneyfunction(e.g.,anemia,bonedisease, cardiovascularmanifestations,hypertension,growthfailure)  Avoidnephrotoxicmedications(NSAIDs.,radiocontrastagents,aminoglycosideabx)  Renalreplacementtherapy,ifsigns/symptomsofuremiaarepresent  Regularlifelongfollow-up 145
  • 147. 147 Review Question Achild has been diagnosed with chronic renal failure.The nurse would question the medical order for: A. Aqueous penicillin. B. Gentamicin (Garamycin). C. Antihypertensives. D. Corticosteroids. 147147
  • 148. 148
  • 149. Review Question A 10-year-old child has just been diagnosed with end-stage renal disease. The nurse gives the child instructions in which foods to avoid, including: A. Eggs B. Carrots C. Rice D. Spinach 149
  • 150. Review Question Which of the following should be considered in the diet of the child with end-stage-renal-disease (ESRD)? A. Limit fluid B. Limit vitamin D-rich food C. Limit calcium-rich food D. Limit carbohydrates 150
  • 151. Chronic Renal Failure: Nursing Care  Provideemotionalsupport tochildandfamily  Assesshydrationstatuscarefully:I&O,dailyweights  Fluidrestrictions&dietaryrestrictionson potassium,phosphorus,&sodium  Maintainstrictsteriletechnique&watchforsignsofinfection  Monitorserumelectrolytelevels;H&H  Givemedications&monitorforsideeffects  Providesmall,frequentfeedings;presentmealsattractively;developmeal plansthatfitarestricteddiet  Dischargeplanningandhomecareteaching 151
  • 152. Review Question  An adolescent with renal failure is receiving epoetin alfa (Epogen) to support erythropoiesis. The nurse questions the teenager about compliance with taking which of the following medications that supports red blood cell (RBC) production? A. Iron supplement B. Zinc supplement C. Calcium supplement D. Magnesium supplement 152
  • 153. 153 Renal Replacement Therapy: Peritoneal Dialysis  Peritonealdialysis-child’sownperitonealcavityactsasthesemi-permeable membraneacrosswhichwaterandsolutesdiffuse 153 •SeevideoPeritonealDialysis(NursingConsiderations,Risks,PatientTeaching)
  • 154. Peritoneal Dialysis  Softcatheterisusedtofillthe abdomenwithadialysissolution  Solutioncontainsdextrose(1.5,2.5, or4.25%)thatpullswasteandextra fluidintotheabdominalcavity  Osmoticpressureofglucosein solutiondrawsfluidfromvascular spacesintotheperitoneum,making availableforexchange/elimination ofexcessfluid&wastes  Dialysisfluidisthendrained 154154154
  • 156. Peritoneal Dialysis: Nursing Care  Assistparentsinlearningperitonealdialysis  Makesurestrictsteriletechniqueisusedatalltimesduringcatheter placementandperitonealdialysis(handhygiene,gloves,masks)  Monitorthechild’sresponsetothetherapy  Assessforcomplications:bleedingfromthecathetersite,signsof infectionatthecathetersite,peritonitis,abdominalhernia  Maintainpatencyoftheperitonealdialysiscatheter:keepitinplace, withoutkinksorpulling,andwiththefluidbagsatthecorrectlevel  Noteifreturningdialysatesolutionhasunusualcolororiscloudy 156 See “Nursing Care Plan: Child Receiving Home Peritoneal Dialysis” – p. 792
  • 157. 157 Review Question Anappropriate nursingdiagnosis forachildreceiving peritoneal dialysisis: A. Fluidvolumedeficitrelatedtosodiumandwaterretention. B. Imbalanced nutrition,greaterthanbodyrequirements relatedto increasedhunger. C. Riskforinfectionrelatedtoinvasiveproceduresanddiminished immunefunctioning. D. Alteredrenaltissueperfusion relatedtohypervolemia. 157157
  • 158. 158 Renal Replacement Therapy: Hemodialysis  Inhemodialysis,amachinefilterswastes,saltsandextrafluidfromtheblood; thecleanbloodisthenreturnedtothebody  Requiresstricttreatmentschedule;adherencetomedications/dietrestrictions  Done3timesaweekfor3to4hoursatadialysiscenter  Attheonset,achildmayexperienceseveralsideeffects(disequilibrium syndrome)—hypotension,dizziness,weakness,nausea,ormusclecramps  SeevideosHemodialysis(Labs,H&H,Cautions)  WhatDoesaKidneyDialysisAccessLookLike?  HemodialysisandHowItWorks 158
  • 159. 159 Hemodialysis: Types of Access 159159
  • 160. Hemodialysis uses a special filter called a dialyzer to remove wastes and extra fluid from the blood 160
  • 161. Hemodialysis: Nursing Care  Weigh child before/ after hemodialysis  Check patency of AV fistula/ graft site by palpating thrill, auscultating bruit  No BP or blood draws on arm with access site  During hemodialysis:  Use strict aseptic technique, standard precautions  Monitor VS, fluid balance, clotting times, blood flow, patency of access site  After dialysis: monitor VS, access site for bleeding, S/S of disequilibrium syndrome  Educate parents:  Daily care of access site  S/S complications (infection, bleeding)  Promote lifelong coping skills 161
  • 162. Review Question  A client has an arteriovenous (AV) fistula in place in the right upper extremity for hemodialysis treatments. When planning care for this client, which of the following measures should the nurse implement to promote client safely? A. Take blood pressures only on the right arm to ensure accuracy B. Use the fistula for all venipunctures and intravenous infusions C. Ensure that small clamps are attached to the AV fistula dressing D. Assess the fistula for the presence of a bruit and thrill 162
  • 163. Renal Replacement Therapy: Kidney Transplantation  Healthy donor kidney surgically placed in lower abdomen  Preferred method of renal replacement therapy in the pediatric population  Blood type compatibility, HLA match; living relative donor preferred  Lifelong immunosuppressive therapy  Complications: opportunistic infection, lymphomas and skin cancer, and hypertension 163 • Rejection – major cause of transplanted kidney loss o S/S rejection: Fever; ↑ BUN & creatinine; pain & tenderness; irritability; weight gain
  • 165. Review Question  The home care nurse is making follow-up visits to a pediatric patient following renal transplant. The nurse assesses the child for which signs of acute graft rejection? A. Hypotension, graft tenderness, and anemia B. Hypertension, oliguria, thirst, and hypothermia C. Fever, hypertension, graft tenderness, and malaise D. Fever, vomiting, hypotension, and copious amounts of dilute urine 165
  • 166. Kidney Transplantation: Nursing Care  Teach child/ parents about transplantation process  Provide emotional support & guidance to the child/ parents  Prepare the child/ parents for the possibility of continuing to need hemodialysis temporarily after the transplant because the transplanted kidney might not work effectively right away  Administer immunosuppressive medications as ordered  Monitor for S/S infection; keep child away from anyone with an infection  Teach child/ parents about follow-up appointments, medications, health promotion, when to call the physician  Teach child/ parents about signs of rejection and infection 166
  • 167. 167 Cryptorchidism Structural Defects of the Reproductive System 167167
  • 168. 168 Cryptorchidism  Failure of one or both testes to descend through inguinal canal; hidden testis  3-6% term; 20-30% preterm infants  Testosterone deficiency, an defective testis, structural problem, early gestational age  Complications: infertility, testicular CA  Usually detected newborn exam  Goals of treatment:  Preserve testicular function  Normal scrotal appearance 168 Bilateral Cryptorchidism
  • 169. 169 Review Question Why isitimportant that thetestes areinthescrotalsac? 169
  • 170. Cryptorchidism: Collaborative Care  Mosttestesspontaneouslydescend  Hormonetherapy–humanchorionic gondadotropin (hCG)  Surgicalprocedure(orchiopexy)iftestes donotdescendintoscrotalsacby6-12 months  Riskoftesticularcancerifuntreated  Monthlytesticularself-examinationis recommendedforallmalesbeginningin puberty,butisessentialinmaleswith historyofundescendedtestis 170 Orchiopexy
  • 171. 171 Review Question  Thenewbornhasbeendiagnosed withcryptorchidism.The physicianhasorderedhumanchorionic gonadotropin (hCG)to beadministered tothebaby.Themotherasksthenursewhythe babyisreceiving thisdrug.Thenurse’sbestexplanation wouldbe thedrugwill: A. Maintainanadequatetemperaturearoundthetestes. B. Preventinfectionsintheundescendedtestes. C. Preventthedevelopmentofcancer. D. Promotedescentofthetestes. 171171
  • 172. Cryptorchidism: Nursing Care  Surgical repair: orchiopexy is done between 6-12 months of age  Postoperatively, keep the surgical area dry for 1-2 days  Encourage bed rest  Monitor voiding  Apply ice to surgical area  Administer prescribed analgesics (acetaminophen or ibuprofen) 172
  • 173. Cryptorchidism: Discharge Instructions  Incision care:  Diaper area should be cleaned well with each diaper change  Sponge baths only for 2 days after surgery  No medicine/ ointment placed over incision  Prevent pulling on the thigh suture postoperatively because the testis could reascend into the abdomen through the inguinal canal if the suture disconnects  Child should avoid straddling activities or strenuous activity for 2-3 weeks  Have the child wear loose clothing  Use analgesics as needed (acetaminophen or ibuprofen)  Observe for redness, warmth, swelling, purulent discharge, fever, increased pain at the incision site (indicative of infection) 173
  • 174. 174 Review Question  Ababyisborn6weeksprematurely.Onadmissiontothe nursery,thenurseisunabletolocateanytesticlesinthe scrotum.Thenurseshould: A. Immediatelynotifythephysicianasthechildisatriskforrenalfailure. B. Notethefindingsinthechild’srecordandtakenofurtheractionatthis time. C. Discusswiththefathertheneedforsurgicalcorrectionofcryptorchidism. D. Catheterizethechildtodetermineifurineispresentinthebladder. 174174
  • 175. 175 Review Question  Whentalkingwiththeparentsofachildoradolescentwhohas ahistoryofcryptorchidism, thenursewillmoststressthe importanceofthechilddoingwhichofthefollowingthings? A. Gettingamumpsvaccineboosterevery5years B. Complying100%withhormonetherapybeginningatage15 C. Wearingatesticularsupport(jockstrap)whileparticipating in sports D. Doingmonthlyself-testicular examinations beginning atage13 175
  • 176. 176