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AGING AND THE EYE
By:
RABIA AMMER
OPTOMETRIST &ORTHOPTIST
GOLD MEDALIST
NORMAL AGING VISION
 What exactly is “normal” in people over the
age of 65?
 Definition: Having no immediately apparent
structural or pathological defect that could
account for reduced function
 Conditions that occur in most older people
(loss of accommodation, miosis) are
considered normal
WE KNOW THIS ALREADY
 Most older people
have “excellent”
vision
 Some eye problems
associated with age
are annoying but
do not cause visual
loss
The Challenges of Aging
How older patients are different from all other
patients
 As people age, some physiologic changes are
inevitable
 Other changes, while not universal, are far
more common than among younger people
 Older people also face unique psycho-social
challenges
 These changes and challenges can lead to a
variety of geriatric syndromes and issues
 These in turn can lead to poor health
outcomes, functional decline, frailty, disability
and dependence
Aging Eye
AGE-DEPENDENT CHANGES
Physiological and Performance Based
General Aging Changes
 Mostly affect appearance
 Seldom affect performance
 Some need monitoring with age
Lens
Aqueous Humor
Retina
Macula
General Aging Changes
 Sclera- thinner, pigment change
 Aqueous Humor- intraocular pressure
 Vitreous Humor- thins, opacity
 Cornea- arcus senilis (Ca and cholesterol),
sensitivity
 Iris- muscles weaken, smaller pupil
 Lens size and thickness , elasticity
 Conjunctiva- dry eye
More General Aging Changes
 Retina- dulls, blood vessel changes
 Optic Nerve- boundaries less defined, fewer
capillaries
 Macula- little or no foveal reflex, drusen and
lipofuscin deposits, pigmentation
 Lids- orbicularis oculi muscle weakens
 Lacrimal Glands/Tears- production
 Orbit- fat loss, enophthalmos
Age Changes in Performance
 Refraction- lens and ciliary muscles
 Results in Presbyopia
 Age 40+
 Acuity and Contrast
 Decreases after age 50
 Due to Brain
 Glare
 Due to lens and vitreous humor
 Dark
 Pupil and Lens
More Performance Changes
 Vitreous Humor
 Haziness
 Flashing Lights
 Moving Spots
 Color
 Discrimination as cones
 Dark
 Pupil and Lens
 Visual Field
 Size 1 to 3 degrees per decade
Near Point Changes
Pupillary Miosis & Light
 Diameter of pupil in
the dark minus
diameter of pupil in
bright light
becomes less & less
with age
 Consequence:
reduction in retinal
illuminance
Visual Difficulties
 < 50% of people
under the age of 40
wear refractive
correction
 Approximately 90%
of people in their
40s or beyond need
lens correction
Visual Function & Age
 Up to age 70, loss in static corrected
acuity can be explained by miosis & lens
changes
 As age increases, the # of people who
achieve normal corrected acuity
decreases
 VERY IMPORTANT: These people show no
signs of ocular disease
CORNEA
 Corneal sensitivity decreases with age
 Touch threshold almost doubles
between the ages of 10 and 80,
especially after 40
 Consider entropion & ectropion
 Advantages and disadvantages
regarding contact lenses
 Corneal curvature changes with age
 Astigmatism increases throughout life
ANTERIOR CHAMBER
 Depth of anterior chamber decreases
 At age 15-20, average depth = 3.6 mm
 At age 70, average depth = 3.0 mm
 This decrease in chamber depth could cause interference
with aqueous flow
LENS
 Lens grows
throughout life
 Axial thickness
increases by about
28% between the
ages of 20 & 70
LENS
 Yellow pigment of the lens absorbs
short wavelengths more than long
ones
 Older people have decreased
sensitivity in violet/blue end of the
spectrum
 White objects may appear yellow &
distinction between blues & greens is
decreased
LENS
 Older people need significantly more light to
achieve the same level of retinal illuminance
 Visual performance of an older individual will be
especially impaired at twilight
 Driving should be given much more thought
(testing conditions vs. reality)
RETINA & BEYOND
 In the absence of pathology, changes in the retina & further
upstream are not directly observable
 Inferences must be made on the basis of visual function
 There’s the rub! Which function(s)?
LIGHT, DARK & GLARE
 Older people
 Cannot reach the
levels of dark
adaptation that
younger people can
LIGHT, DARK & GLARE
 Older people - more sensitive to glare & take longer to
recover
VISUAL FUNCTION & AGE
 Inability to achieve at least 20/25 acuity cannot be explained
for about 10% of people between the ages of 75 & 85
 Visual acuity has long been understood (at least by the
rehabilitation community) to be an inadequate measure of
visual function
HIGH - LOW CONTRAST ACUITY
CONTRAST SENSITIVITY
 High-frequency cut-off
can be mimicked by
artificial pupils & neutral
density filters
 This means that the lens
and pupil changes are
responsible for upper
frequency loss.
VERNIER ACUITY
 Observer is asked to align objects, not recognize
them (hyperacuity task)
 Segments of a line, points of light, etc. are aligned
vertically or horizontally
 This ability remains intact throughout life
VERNIER ACUITY
STILES-CRAWFORD EFFECT
 Tests the directional sensitivity of the retina
 Relies on proper alignment of the retinal
receptors
 Light entering different points of the pupil is
differently absorbed by receptors
STILES-CRAWFORD EFFECT
STILES-CRAWFORD EFFECT
COLOUR PERCEPTION
 There has always been a debate
concerning colour vision changes
in older people
 Question:
 To what degree are changes in colour
perception due to optical media
(especially the lens) & to what extent
are they due to retinal changes?
 Are the short-wavelength (blue)
cones playing a big role?
OPTICAL CORRECTION
SYMMETRY PERCEPTION
 Detection of
symmetry is an
important visual
ability
 Consider how many
objects in our
environment are
approximately
symmetrical (faces,
butterflies etc)
SYMMETRY PERCEPTION
 Our data show a
decline in symmetry
perception in
people over 65 …
but it’s an
organized change
USEFUL FIELD OF VIEW
USEFUL FIELD OF VIEW
USEFUL FIELD OF VIEW
Age-Related Changes
Diseases and Syndromes
Cataracts
 Symptoms: increase in lens opacity
 Peripheral to nuclear
 Causes/Risk Factors:
 UV light/free radicals
 Glycation
 Corticosteroids
 Diabetes
Cataracts
Cataract
 What is it?
 Clouding of the eye’s lens that
causes loss of vision.
 Who is at higher risk?
 Most cataract are related to aging
 Other risk factors
• Diabetes
• Smoking
• Exposure to sunlight
Cataract
Same scene as viewed by a
person with cataract
Normal vision
Cataract
 Symptoms
 Cloudy or blurred vision.
 Colors that may not appear as
bright as they once did.
 Glare.
 Poor night vision.
Cataract
 Treatment options
 Glasses
 Better lighting
 Surgery
Cataract
 What can you do?
 Eat a healthy diet.
 Wear sunglasses and a brimmed hat when
outdoors.
 Don’t smoke.
Cataract
Glaucoma
 What is it?
 A group of eye diseases that can
damage the optic nerve in the
eye.
 Glaucoma can develop in one or
both eyes.
 Primary open-angle glaucoma is
the most common form.
Glaucoma
 Who is at higher risk?
 African Americans over age 40.
 Everyone over the age of 60, especially Mexican
Americans.
 People with a family history of glaucoma.
Glaucoma
Same scene as viewed by a
person with glaucoma
Normal vision
Glaucoma
 Symptoms
 No early warning signs or
symptoms
 No pain
 Loss of side vision
 Treatment options
 Medications, usually eye drops
 Laser or conventional surgery
Glaucoma
 What can you do?
 People at higher risk should get a
comprehensive dilated eye exam
every one to two years or as
instructed by your eye care
professional.
Glaucoma
Age-Related Macular
Degeneration (AMD)
Age-Related Macular
Degeneration (AMD)
 What is it?
 Common among people aged 60 or older.
 Can damage the macula, which is needed for
sharp, detailed central vision.
 Who is at higher risk?
 The greatest risk factor is age.
 Other risk factors
 Smoking.
 Family history.
 Obesity.
 Race. Caucasians are more likely to lose vision from
AMD.
Age-Related Macular
Degeneration (AMD)
Same scene as viewed by a
person with AMD
Normal vision
Age-Related Macular
Degeneration (AMD)
 Symptoms
 No pain.
 Blurred vision.
 Drusen (can only be seen by an
eye care professional).
Age-Related Macular
Degeneration (AMD)
Normal
Dry AMD Wet AMD
 Treatment options
 Age-Related Eye Disease Study (AREDS) special
vitamins/minerals supplement formulation.
 Laser surgery.
 Eye injections.
 Photodynamic therapy.
Age-Related Macular
Degeneration (AMD)
 What can you do?
 Eat a healthy diet
 Don’t smoke, or stop smoking
 Maintain normal blood pressure
 Maintain a healthy weight
 Exercise
Age-Related Macular
Degeneration (AMD)
Diabetic Retinopthy
 What is it?
 A group of eye problems
associated with diabetes.
 Diabetic retinopathy is a leading
cause of vision loss and blindness.
Diabetic Retinopthy
 Who is at higher risk?
 People with diabetes.
 The longer someone has
diabetes, the more likely it is he
or she will get diabetic
retinopathy.
Diabetic Retinopthy
Same scene as viewed by a
person with diabetic retinopathy
Normal vision
Diabetic Retinopthy
Diabetic Eye Disease
 Symptoms
 No early warning signs or symptoms
 Early detection and timely
treatment can reduce the risk
of vision loss.
 Treatment options
 Laser treatment
 Surgery
Diabetic Eye Disease
 What can you do?
 Control your ABCs - A1C, blood
pressure, and cholesterol.
 Take your medications as directed.
 Maintain a healthy weight.
 Exercise.
 Don’t smoke.
 Have a dilated eye exam at least
once a year.
Dry Eye
 What is it?
 The eye does not produce tears
properly.
 Tears evaporate too quickly.
 Inflammation of the surface of the
eye may occur along with dry
eye.
 Who is at higher risk?
 Women often experience dry eye more than men.
 Dry eye can occur at any age.
 Older adults frequently experience dryness of the
eyes.
Dry Eye
 Symptoms
 Stinging or burning of the eye.
 Feeling as if sand or grit is in the eye.
 Episodes of excess tears following dry
eye periods.
 A stringy discharge from the eye.
 Pain and redness of the eye.
 Episodes of blurred vision.
Dry Eye
 Symptoms
 Heavy eyelids.
 Decreased tearing or inability to shed tears when
crying.
 Uncomfortable contact lenses.
 Decreased tolerance to any activity that requires
prolonged visual attention.
 Eye fatigue.
Dry Eye
 Treatment options
 Using artificial tears, prescription eye drops, gels, gel
inserts, and ointments.
 Wearing glasses or sunglasses.
 Getting punctal plugs.
Dry Eye
 What can you do?
 Use an air cleaner to filter dust
 Avoid dry conditions
 Use lubricating eye drops
 Visit an eye care professional
Dry Eye
Low Vision Aids
(Treatment Option In Old Age)
Low Vision Aids
 What is it?
 A visual impairment that is not
corrected by standard
eyeglasses, contact lenses,
medication, or surgery.
 It interferes with the ability to
perform everyday activities.
Low Vision
 Who is at higher risk?
 People with eye disease.
 Old aged people.
 Some people develop vision loss
after eye injuries or from birth
defects.
Low Vision
 Treatment options
 Vision rehabilitation.
 What can you do?
 See a specialist in low vision.
 Talk to your eye care professional
about vision rehabilitation.
 Use low vision devices.
Low Vision

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Aging and The Eye

  • 1.
  • 2. AGING AND THE EYE By: RABIA AMMER OPTOMETRIST &ORTHOPTIST GOLD MEDALIST
  • 3. NORMAL AGING VISION  What exactly is “normal” in people over the age of 65?  Definition: Having no immediately apparent structural or pathological defect that could account for reduced function  Conditions that occur in most older people (loss of accommodation, miosis) are considered normal
  • 4. WE KNOW THIS ALREADY  Most older people have “excellent” vision  Some eye problems associated with age are annoying but do not cause visual loss
  • 5. The Challenges of Aging How older patients are different from all other patients  As people age, some physiologic changes are inevitable  Other changes, while not universal, are far more common than among younger people  Older people also face unique psycho-social challenges  These changes and challenges can lead to a variety of geriatric syndromes and issues  These in turn can lead to poor health outcomes, functional decline, frailty, disability and dependence
  • 8. General Aging Changes  Mostly affect appearance  Seldom affect performance  Some need monitoring with age Lens Aqueous Humor Retina Macula
  • 9. General Aging Changes  Sclera- thinner, pigment change  Aqueous Humor- intraocular pressure  Vitreous Humor- thins, opacity  Cornea- arcus senilis (Ca and cholesterol), sensitivity  Iris- muscles weaken, smaller pupil  Lens size and thickness , elasticity  Conjunctiva- dry eye
  • 10. More General Aging Changes  Retina- dulls, blood vessel changes  Optic Nerve- boundaries less defined, fewer capillaries  Macula- little or no foveal reflex, drusen and lipofuscin deposits, pigmentation  Lids- orbicularis oculi muscle weakens  Lacrimal Glands/Tears- production  Orbit- fat loss, enophthalmos
  • 11. Age Changes in Performance  Refraction- lens and ciliary muscles  Results in Presbyopia  Age 40+  Acuity and Contrast  Decreases after age 50  Due to Brain  Glare  Due to lens and vitreous humor  Dark  Pupil and Lens
  • 12. More Performance Changes  Vitreous Humor  Haziness  Flashing Lights  Moving Spots  Color  Discrimination as cones  Dark  Pupil and Lens  Visual Field  Size 1 to 3 degrees per decade
  • 14. Pupillary Miosis & Light  Diameter of pupil in the dark minus diameter of pupil in bright light becomes less & less with age  Consequence: reduction in retinal illuminance
  • 15. Visual Difficulties  < 50% of people under the age of 40 wear refractive correction  Approximately 90% of people in their 40s or beyond need lens correction
  • 16. Visual Function & Age  Up to age 70, loss in static corrected acuity can be explained by miosis & lens changes  As age increases, the # of people who achieve normal corrected acuity decreases  VERY IMPORTANT: These people show no signs of ocular disease
  • 17. CORNEA  Corneal sensitivity decreases with age  Touch threshold almost doubles between the ages of 10 and 80, especially after 40  Consider entropion & ectropion  Advantages and disadvantages regarding contact lenses  Corneal curvature changes with age  Astigmatism increases throughout life
  • 18. ANTERIOR CHAMBER  Depth of anterior chamber decreases  At age 15-20, average depth = 3.6 mm  At age 70, average depth = 3.0 mm  This decrease in chamber depth could cause interference with aqueous flow
  • 19. LENS  Lens grows throughout life  Axial thickness increases by about 28% between the ages of 20 & 70
  • 20. LENS  Yellow pigment of the lens absorbs short wavelengths more than long ones  Older people have decreased sensitivity in violet/blue end of the spectrum  White objects may appear yellow & distinction between blues & greens is decreased
  • 21. LENS  Older people need significantly more light to achieve the same level of retinal illuminance  Visual performance of an older individual will be especially impaired at twilight  Driving should be given much more thought (testing conditions vs. reality)
  • 22. RETINA & BEYOND  In the absence of pathology, changes in the retina & further upstream are not directly observable  Inferences must be made on the basis of visual function  There’s the rub! Which function(s)?
  • 23. LIGHT, DARK & GLARE  Older people  Cannot reach the levels of dark adaptation that younger people can
  • 24. LIGHT, DARK & GLARE  Older people - more sensitive to glare & take longer to recover
  • 25. VISUAL FUNCTION & AGE  Inability to achieve at least 20/25 acuity cannot be explained for about 10% of people between the ages of 75 & 85  Visual acuity has long been understood (at least by the rehabilitation community) to be an inadequate measure of visual function
  • 26. HIGH - LOW CONTRAST ACUITY
  • 27. CONTRAST SENSITIVITY  High-frequency cut-off can be mimicked by artificial pupils & neutral density filters  This means that the lens and pupil changes are responsible for upper frequency loss.
  • 28. VERNIER ACUITY  Observer is asked to align objects, not recognize them (hyperacuity task)  Segments of a line, points of light, etc. are aligned vertically or horizontally  This ability remains intact throughout life
  • 30. STILES-CRAWFORD EFFECT  Tests the directional sensitivity of the retina  Relies on proper alignment of the retinal receptors  Light entering different points of the pupil is differently absorbed by receptors
  • 33. COLOUR PERCEPTION  There has always been a debate concerning colour vision changes in older people  Question:  To what degree are changes in colour perception due to optical media (especially the lens) & to what extent are they due to retinal changes?  Are the short-wavelength (blue) cones playing a big role?
  • 35. SYMMETRY PERCEPTION  Detection of symmetry is an important visual ability  Consider how many objects in our environment are approximately symmetrical (faces, butterflies etc)
  • 36. SYMMETRY PERCEPTION  Our data show a decline in symmetry perception in people over 65 … but it’s an organized change
  • 41. Cataracts  Symptoms: increase in lens opacity  Peripheral to nuclear  Causes/Risk Factors:  UV light/free radicals  Glycation  Corticosteroids  Diabetes
  • 43. Cataract  What is it?  Clouding of the eye’s lens that causes loss of vision.
  • 44.  Who is at higher risk?  Most cataract are related to aging  Other risk factors • Diabetes • Smoking • Exposure to sunlight Cataract
  • 45. Same scene as viewed by a person with cataract Normal vision Cataract
  • 46.  Symptoms  Cloudy or blurred vision.  Colors that may not appear as bright as they once did.  Glare.  Poor night vision. Cataract
  • 47.  Treatment options  Glasses  Better lighting  Surgery Cataract
  • 48.  What can you do?  Eat a healthy diet.  Wear sunglasses and a brimmed hat when outdoors.  Don’t smoke. Cataract
  • 50.  What is it?  A group of eye diseases that can damage the optic nerve in the eye.  Glaucoma can develop in one or both eyes.  Primary open-angle glaucoma is the most common form. Glaucoma
  • 51.  Who is at higher risk?  African Americans over age 40.  Everyone over the age of 60, especially Mexican Americans.  People with a family history of glaucoma. Glaucoma
  • 52. Same scene as viewed by a person with glaucoma Normal vision Glaucoma
  • 53.  Symptoms  No early warning signs or symptoms  No pain  Loss of side vision  Treatment options  Medications, usually eye drops  Laser or conventional surgery Glaucoma
  • 54.  What can you do?  People at higher risk should get a comprehensive dilated eye exam every one to two years or as instructed by your eye care professional. Glaucoma
  • 56. Age-Related Macular Degeneration (AMD)  What is it?  Common among people aged 60 or older.  Can damage the macula, which is needed for sharp, detailed central vision.
  • 57.  Who is at higher risk?  The greatest risk factor is age.  Other risk factors  Smoking.  Family history.  Obesity.  Race. Caucasians are more likely to lose vision from AMD. Age-Related Macular Degeneration (AMD)
  • 58. Same scene as viewed by a person with AMD Normal vision Age-Related Macular Degeneration (AMD)
  • 59.  Symptoms  No pain.  Blurred vision.  Drusen (can only be seen by an eye care professional). Age-Related Macular Degeneration (AMD)
  • 61.
  • 62.  Treatment options  Age-Related Eye Disease Study (AREDS) special vitamins/minerals supplement formulation.  Laser surgery.  Eye injections.  Photodynamic therapy. Age-Related Macular Degeneration (AMD)
  • 63.  What can you do?  Eat a healthy diet  Don’t smoke, or stop smoking  Maintain normal blood pressure  Maintain a healthy weight  Exercise Age-Related Macular Degeneration (AMD)
  • 65.  What is it?  A group of eye problems associated with diabetes.  Diabetic retinopathy is a leading cause of vision loss and blindness. Diabetic Retinopthy
  • 66.  Who is at higher risk?  People with diabetes.  The longer someone has diabetes, the more likely it is he or she will get diabetic retinopathy. Diabetic Retinopthy
  • 67. Same scene as viewed by a person with diabetic retinopathy Normal vision Diabetic Retinopthy
  • 68. Diabetic Eye Disease  Symptoms  No early warning signs or symptoms  Early detection and timely treatment can reduce the risk of vision loss.  Treatment options  Laser treatment  Surgery
  • 69. Diabetic Eye Disease  What can you do?  Control your ABCs - A1C, blood pressure, and cholesterol.  Take your medications as directed.  Maintain a healthy weight.  Exercise.  Don’t smoke.  Have a dilated eye exam at least once a year.
  • 70. Dry Eye  What is it?  The eye does not produce tears properly.  Tears evaporate too quickly.  Inflammation of the surface of the eye may occur along with dry eye.
  • 71.  Who is at higher risk?  Women often experience dry eye more than men.  Dry eye can occur at any age.  Older adults frequently experience dryness of the eyes. Dry Eye
  • 72.  Symptoms  Stinging or burning of the eye.  Feeling as if sand or grit is in the eye.  Episodes of excess tears following dry eye periods.  A stringy discharge from the eye.  Pain and redness of the eye.  Episodes of blurred vision. Dry Eye
  • 73.  Symptoms  Heavy eyelids.  Decreased tearing or inability to shed tears when crying.  Uncomfortable contact lenses.  Decreased tolerance to any activity that requires prolonged visual attention.  Eye fatigue. Dry Eye
  • 74.  Treatment options  Using artificial tears, prescription eye drops, gels, gel inserts, and ointments.  Wearing glasses or sunglasses.  Getting punctal plugs. Dry Eye
  • 75.  What can you do?  Use an air cleaner to filter dust  Avoid dry conditions  Use lubricating eye drops  Visit an eye care professional Dry Eye
  • 76. Low Vision Aids (Treatment Option In Old Age)
  • 78.  What is it?  A visual impairment that is not corrected by standard eyeglasses, contact lenses, medication, or surgery.  It interferes with the ability to perform everyday activities. Low Vision
  • 79.  Who is at higher risk?  People with eye disease.  Old aged people.  Some people develop vision loss after eye injuries or from birth defects. Low Vision
  • 80.  Treatment options  Vision rehabilitation.  What can you do?  See a specialist in low vision.  Talk to your eye care professional about vision rehabilitation.  Use low vision devices. Low Vision