The posterior abdominal region contains several important structures. The lumbar vertebrae and sacrum form the bony framework in the midline. The psoas major and minor muscles cover the sides of the lumbar vertebrae and attach to the femur. The quadratus lumborum muscles fill the space between rib 12 and the iliac crest laterally. The suprarenal glands are located superior to each kidney within the perinephric fat. Major blood vessels include the abdominal aorta, which bifurcates into the common iliac arteries at L4, and the inferior vena cava, which returns blood to the heart. Nerves in the region include the sympathetic trunks and splanchnic
posterior abdominal wall is most important chapter in undergraduate curriculum.After read the above presentation you have to able describe about posterior abdominal wall structures like Muscles ,Bony part and Ligamental part. Then nervous innervation of Lumbarplexus and Autonomic nervous system of posterior abdominal wall including sympathetic chain
Abdominal anatomical and symptoms and symptoms and Marasmus of the fetus first and symptoms to the signs on a verification dsujŝkkkllllllllljnvvvhĵjbvvghhjjĵkķkkkkkkkkkkkllķ
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Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
3. Bones
Lumbar vertebrae and the sacrum
• Projecting into the midline of the posterior abdominal area are the
bodies of the five lumbar vertebrae
• The prominence of these structures in this region is due to the
secondary curvature (a forward convexity)
• The lumbar vertebrae can be distinguished from cervical and thoracic
vertebrae because of their size
4. Bones
Ribs
• Superiorly, ribs XI and XII complete the bony framework of the
posterior abdominal wall
• These ribs are unique in that they do not articulate with the sternum
or other ribs
• They have a single articular facets on their heads, and they do not
have necks or tubercles
• Rib XI is posterior to the superior part of the left kidney, and rib XII is
posterior to the superior part of both kidneys
6. Muscles
• Muscles forming the medial, lateral, inferior, and superior boundaries
of the posterior abdominal region
• Medially are the psoas major and minor muscles, laterally is the
quadratus lumborum muscle, inferiorly is the iliacus muscle, and
superiorly is the diaphragm
Psoas major and minor
• Cover the anterolateral surface of the bodies of the lumbar vertebrae,
• Each of these muscles arises from the bodies of vertebra TXII and all
five lumbar vertebrae
7. Muscles
• Associated with the psoas major muscle is the psoas minor muscle,
which is sometimes absent
• Lying on the surface of the psoas major, this slender muscle arises
from vertebrae TXII and LI and the intervening intervertebral disc
• Its long tendon inserts into the pectineal line of the pelvic brim and
the iliopubic eminence.
Quadratus lumborum
• Fill the space between rib XII and the iliac crest
• They are overlapped medially by the psoas major muscles
• Along their lateral borders are the transversus abdominis muscles
9. Muscles
• Each quadratus lumborum muscle arises from the transverse process
of vertebra LV
• The muscle attaches superiorly to the transverse process of the first
four lumbar vertebrae and the inferior border of rib XII.
Iliacus
• Inferiorly, an iliacus muscle fills the iliac fossa on each side
• The muscle passes inferiorly, joins with the psoas major muscle, and
attaches to the lesser trochanter of the femur
• As they pass into the thigh, these combined muscles are referred to
as the iliopsoas muscle
12. Viscera
Suprarenal glands
• Associated with the superior pole of each kidney
• They consist of an outer cortex and an inner medulla.
• The right gland is shaped like a pyramid, whereas the left gland is
semilunar in shape and the larger of the two.
• They are surrounded by the perinephric fat
• Enclosed in the renal fascia, though a thin septum separates each
gland from its associated kidney
14. Vasculature
Abdominal aorta
• Begins at the aortic hiatus of the diaphragm as a midline structure at
approximately the lower level of vertebra TXII
• At vertebra LIV it divides into the right and left common iliac arteries.
• This bifurcation can be visualized on the anterior abdominal wall as a
point approximately 2.5 cm below the umbilicus or even with a line
extending between the highest points of the iliac crest.
• As the abdominal aorta passes through the posterior abdominal
region, the prevertebral plexus of nerves and ganglia covers its
anterior surface
17. Inferior vena cava
• Returns blood from all structures below the diaphragm to the right atrium
of the heart
• Formed when the two common iliac veins come together at the level of
vertebra LV, just to the right of midline
• It ascends through the posterior abdominal region anterior to the vertebral
column immediately to the right of the abdominal aorta
• Leaves the abdomen by piercing the central tendon of the diaphragm at
the level of vertebra TVIII
• Tributaries include the: 1.common iliac veins, 2. lumbar veins, 3. right
testicular or ovarian vein, 4. renal veins,5. right suprarenal vein, 6. inferior
phrenic veins, and 7. hepatic veins
21. Nervous system in the posterior abdominal
region
• Several important components of the nervous system are in the
posterior abdominal region.
• The sympathetic trunks and associated splanchnic nerves,
• The plexus of nerves and ganglia associated with the abdominal
aorta,
• And the lumbar plexus of nerves.
The pedicles are short and stocky, the transverse processes are long and slender, and the spinous processes are large and stubby
The vertebral bodies are massive and progressively increase in size from vertebra LI to LV
The articular processes are large and oriented medially and laterally, which promotes flexion and extension in this part of the vertebral column
Between each lumbar vertebra is an intervertebral disc, which completes this part of the midline boundary of the posterior abdominal wall
Also, rib XII serves as a point of attachment for numerous muscles and ligaments
Passing inferiorly along the pelvic brim, each muscle continues into the anterior thigh, under the inguinal ligament, to attach to the lesser trochanter of the femur
The psoas major muscle flexes the thigh at the hip joint when the trunk is stabilized and flexes the trunk against gravity when the body is supine. It is innervated by anterior rami of nerves L1 to L3
Diaphragm
Superiorly, the diaphragm forms the boundary of the posterior abdominal region
This musculotendinous sheet also separates the abdominal cavity from the thoracic cavity.
Structurally, the diaphragm consists of a central tendinous part into which the circumferentially arranged muscle fibers attach anchored to the lumbar vertebrae by musculotendinous crura, which blend with the anterior longitudinal ligament of the vertebral column
The crura are connected across the midline by a tendinous arch (the median arcuate ligament), which passes anterior to the aorta
Lateral to the crura, a second tendinous arch is formed by the fascia covering the upper part of the psoas major muscle. This is the medial arcuate ligament, which is attached medially to the sides of vertebrae LI and LII and laterally to the transverse process of vertebra LI
A third tendinous arch, the lateral arcuate ligament, is formed by a thickening in the fascia that covers the quadratus lumborum
Anterior to the right suprarenal gland is part of the right lobe of the liver and the inferior vena cava, whereas anterior to the left suprarenal gland is part of the stomach, pancreas, and, on occasion, the spleen. Parts of the diaphragm are posterior to both glands
Suprarenal vasculature
The arterial supply to the suprarenal glands is extensive and arises from three primary sources
As the bilateral inferior phrenic arteries pass upward from the abdominal aorta to the diaphragm, they give off multiple branches (superior suprarenal arteries) to the suprarenal glands.
A middle branch (middle suprarenal artery) to the suprarenal glands usually arises directly from the abdominal aorta.
Inferior branches (inferior suprarenal arteries) from the renal arteries pass upward to the suprarenal glands
In contrast to this multiple arterial supply is the venous drainage, which usually consists of a single vein leaving the hilum of each gland (suprarenal vein)
mainly innervated by preganglionic sympathetic fibers from spinal levels T8-L1
Branches of the abdominal aorta can be classified as:
Visceral branches supplying organs, posterior branches, or terminal branches
The paired visceral branches of the abdominal aorta (Fig. 4.164) include: the middle suprarenal arteries, the renal arteries, the testicular or ovarian arteries
Posterior branches: inferior phrenic arteries, the lumbar arteries, and the median sacral artery
Branches of the abdominal aorta can be classified as:
Visceral branches supplying organs, posterior branches, or terminal branches
The paired visceral branches of the abdominal aorta (Fig. 4.164) include: the middle suprarenal arteries, the renal arteries, the testicular or ovarian arteries
Posterior branches: inferior phrenic arteries, the lumbar arteries, and the median sacral artery
During its course, the anterior surface of the inferior vena cava is crossed by the right common iliac artery, the root of the mesentery, the right testicular or ovarian artery, the inferior part of the duodenum, the head of the pancreas, the superior part of the duodenum, the bile duct, the portal vein, and the liver, which overlaps and on occasion completely surrounds the vena cava
Lymphatic drainage from most deep structures and regions of the body below the diaphragm converges mainly on collections of lymph nodes and vessels associated with the major blood vessels of the posterior abdominal region
The lymph then predominantly drains into the thoracic duct
The sympathetic trunks pass through the posterior abdominal region anterolateral to the lumbar vertebral bodies, before continuing across the sacral promontory and into the pelvic cavity
lumbar splanchnic nerves (Fig. 4.169). These components of the nervous system pass from the sympathetic trunks to the plexus of nerves and ganglia associated with the abdominal aorta Usually two to four lumbar splanchnic nerves carry preganglionic sympathetic fibers and visceral afferent fibers
The abdominal prevertebral plexus is a network of nerve fibers surrounding the abdominal aorta. It extends from the aortic hiatus of the diaphragm to the bifurcation of the aorta into the right and left common iliac arteries. Along its route, it is subdivided into smaller, named plexuses
celiac plexus
the abdominal aortic plexus
superior hypogastric plexus